烟雾病和烟雾综合征：来自印度尼西亚多中心私立医院的病例系列

IF 0.7 4区医学 Q4 NEUROSCIENCES

Neurocirugia Pub Date : 2025-05-01 DOI:10.1016/j.neucir.2024.10.012

Rusli Muljadi , Koesbandono , Teodorus Alfons Pratama , Gilbert Sterling Octavius

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引用次数: 0

摘要

背景烟雾病（MMD）和烟雾综合征（MMS）在印度尼西亚被认为是罕见的，没有任何适当的流行病学数据支持这一说法。因此，本病例系列旨在从印度尼西亚一家多中心私立医院的角度评估所有烟雾病和MMS病例。方法对2019年1月至2023年12月的图片存档和通信系统（PACS）数据进行描述性分析。纳入标准包括所有符合烟雾病和/或MMS放射学标准的患者，而仅接受脑非对比计算机断层扫描（CT）扫描的患者被排除在外。结果2019年至2023年共有58,905次独特的MRI扫描。该队列包括8名女性和2名男性，中位年龄为37岁（7-65岁）。3例可能为烟雾病。其中MMD 6例，MMS 1例。因此，四年的患病率约为每10万次扫描11.9例。在确诊的Moya-Moya病例中，大多数（4/7）是缺血性亚型，其次是癫痫（脑电图显示脑电波减慢）和TIA各1例。最常见的症状是四肢无力（N = 7），其次是头痛（N = 5）。4例患者接受手术治疗，其中3例为颞上动脉至大脑中动脉（STA-MCA）搭桥手术，1例为脑-硬膜-肌-动脉-颅周合并症（EDMAPS）。结论印度尼西亚烟雾病和MMS的确诊病例较少，可能表明印度尼西亚烟雾病和MMS的患病率较低，也可能表明这些病例的诊断不足。

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Moyamoya disease and moyamoya syndrome: A case series from multicentre private hospitals in Indonesia

Background

Moyamoya disease (MMD) and moyamoya syndrome (MMS) are considered rare in Indonesia, without any proper epidemiological data backing this claim. Hence, this case series aims to assess all MMD and MMS cases from the perspective of a multicentre private hospital in Indonesia.

Methods

This is a descriptive analysis using data from the picture archiving and communication system (PACS) from January 2019 to December 2023. The inclusion criteria included all patients who fulfilled the radiological criteria for MMD and/or MMS, while patients who only underwent brain non-contrast computed tomography (CT) scans were excluded.

Results

There are 58,905 unique MRI scans from 2019 to 2023. The cohort comprises 8 females and 2 males, with a median age of 37 (7–65) years old. Three cases are probable MMD. with six MMD cases and one MMS case. Therefore, the prevalence rate for the four years is approximately 11.9 cases per 100,000 scans. Out of the confirmed Moya-Moya cases, the majority (4/7) are ischemic subtypes, followed by epileptic (electroencephalography shows slowing brain waves) and TIA in one case each. The most common presenting symptom is weakness in the extremity (N = 7), followed by headache (N = 5). Four patients underwent operative procedures, with three of them being superior temporal artery to middle cerebral artery (STA-MCA) bypass procedures and one of them being encephalo-duro-myo-arterio-pericraniosynangiosis (EDMAPS).

Conclusion

The paucity of confirmed cases either points towards the low prevalence of MMD and MMS in Indonesia or the underdiagnosis of these cases.

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来源期刊

Neurocirugia 医学-神经科学

CiteScore

1.30

自引率

0.00%

发文量

审稿时长

60 days

期刊介绍： Neurocirugía is the official Journal of the Spanish Society of Neurosurgery (SENEC). It is published every 2 months (6 issues per year). Neurocirugía will consider for publication, original clinical and experimental scientific works associated with neurosurgery and other related neurological sciences. All manuscripts are submitted for review by experts in the field (peer review) and are carried out anonymously (double blind). The Journal accepts works written in Spanish or English.