{"title":"Moyamoya disease and moyamoya syndrome: A case series from multicentre private hospitals in Indonesia","authors":"Rusli Muljadi , Koesbandono , Teodorus Alfons Pratama , Gilbert Sterling Octavius","doi":"10.1016/j.neucir.2024.10.012","DOIUrl":"10.1016/j.neucir.2024.10.012","url":null,"abstract":"<div><h3>Background</h3><div>Moyamoya disease (MMD) and moyamoya syndrome (MMS) are considered rare in Indonesia, without any proper epidemiological data backing this claim. Hence, this case series aims to assess all MMD and MMS cases from the perspective of a multicentre private hospital in Indonesia.</div></div><div><h3>Methods</h3><div>This is a descriptive analysis using data from the picture archiving and communication system (PACS) from January 2019 to December 2023. The inclusion criteria included all patients who fulfilled the radiological criteria for MMD and/or MMS, while patients who only underwent brain non-contrast computed tomography (CT) scans were excluded.</div></div><div><h3>Results</h3><div>There are 58,905 unique MRI scans from 2019 to 2023. The cohort comprises 8 females and 2 males, with a median age of 37 (7–65) years old. Three cases are probable MMD. with six MMD cases and one MMS case. Therefore, the prevalence rate for the four years is approximately 11.9 cases per 100,000 scans. Out of the confirmed Moya-Moya cases, the majority (4/7) are ischemic subtypes, followed by epileptic (electroencephalography shows slowing brain waves) and TIA in one case each. The most common presenting symptom is weakness in the extremity (N = 7), followed by headache (N = 5). Four patients underwent operative procedures, with three of them being superior temporal artery to middle cerebral artery (STA-MCA) bypass procedures and one of them being encephalo-duro-myo-arterio-pericraniosynangiosis (EDMAPS).</div></div><div><h3>Conclusion</h3><div>The paucity of confirmed cases either points towards the low prevalence of MMD and MMS in Indonesia or the underdiagnosis of these cases.</div></div>","PeriodicalId":51145,"journal":{"name":"Neurocirugia","volume":"36 3","pages":"Pages 151-160"},"PeriodicalIF":0.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143895895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NeurocirugiaPub Date : 2025-05-01DOI: 10.1016/j.neucir.2024.11.004
Marlon Manuel Ortiz Machín, Omar López Arbolay, Carlos Roberto Vargas Gálvez
{"title":"Consideraciones diagnósticas de los tumores de la región selar según su geometría de crecimiento vectorial","authors":"Marlon Manuel Ortiz Machín, Omar López Arbolay, Carlos Roberto Vargas Gálvez","doi":"10.1016/j.neucir.2024.11.004","DOIUrl":"10.1016/j.neucir.2024.11.004","url":null,"abstract":"<div><h3>Introduction</h3><div>Sellar and parasellar tumors are frequent lesions in neurosurgical practice, highlighting pituitary adenomas, craniopharyngiomas, and sellar tubercle meningiomas. The clinical manifestations are similar, however; There are imaging aspects that differentiate them.</div></div><div><h3>Objective</h3><div>Show imaging aspects of tumors in the sellar and parasellar region that guide their histopathological diagnosis.</div></div><div><h3>Method</h3><div>A descriptive, longitudinal and prospective study was carried out that included 200 patients from the Hermanos Ameijeiras Hospital, of which 120 had a histopathological diagnosis of pituitary adenoma, 50 of craniopharyngioma and 30 of sellar tubercle meningioma. The variations in the displacement of the point of the anterior communicating arterial complex and in the premammillary angle were analyzed by means of a cerebral nuclear magnetic resonance study. For data analysis, absolute and relative frequencies were used as summary measures.</div></div><div><h3>Results</h3><div>A cephalic displacement of the anterior communicating arterial complex was evident in the craniopharyngiomas, of 10 -11.9<!--> <!-->mm (84.0%); in pituitary macroadenomas, 12-14<!--> <!-->mm (78.3%); and in sellar tubercle meningioma, ≥ 14 (86.6%) mm. When evaluating the premammillary angle, pituitary adenomas were identified between 85°-95° (73.3%); in craniopharyngiomas, <<!--> <!-->85° (90.0%); and in meningiomas of the sellar tubercle, between 85-95° (86.6%).</div></div><div><h3>Conclusions</h3><div>The present study allows us to identify imaging characteristics in sellar and parasellar tumors that guide with high certainty the histopathological diagnosis and thus establish a more effective treatment.</div></div>","PeriodicalId":51145,"journal":{"name":"Neurocirugia","volume":"36 3","pages":"Pages 179-184"},"PeriodicalIF":0.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143895898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NeurocirugiaPub Date : 2025-05-01DOI: 10.1016/j.neucir.2024.10.006
Alejandro Augusto Ortega Rodriguez, Santiago Nicolás Valbuena Dussan, José Luís Caro Cardera, Jordi de Manuel-Rimbau Muñoz
{"title":"Cord compression due to atypical T-cell lymphoma from paraspinal soft tissue: Report of a case","authors":"Alejandro Augusto Ortega Rodriguez, Santiago Nicolás Valbuena Dussan, José Luís Caro Cardera, Jordi de Manuel-Rimbau Muñoz","doi":"10.1016/j.neucir.2024.10.006","DOIUrl":"10.1016/j.neucir.2024.10.006","url":null,"abstract":"<div><div>During lymphoma’s natural history of disease, 5–10% of cases may develop Central Nervous affectation. We present the case of a 57-years-old man with less than 24 h of onset symptoms of paraparesis, lower limb hypoesthesia and sphincter dysfunction who was operated due to dorsal tumor with epidural component which caused severe cord compression. Pathological analysis concluded atypical T-cell lymphoblastic lymphoma, a rare subtype of lymphoma which accounts 1%−2% of all Non-Hodgkin Lymphomas. Our case was particularly aggressive and atypical due to its origin in paraspinal soft tissue. Despite specific treatment, the patient presented an early epidural relapse, frequent in this lymphoma subtype.</div></div>","PeriodicalId":51145,"journal":{"name":"Neurocirugia","volume":"36 3","pages":"Pages 199-203"},"PeriodicalIF":0.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143895900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NeurocirugiaPub Date : 2025-05-01DOI: 10.1016/j.neucir.2024.11.002
Adrián Fernández García, Carlos Alberto Rodríguez Arias, Estefanía Utiel Monsálvez, Herbert Daniel Jiménez Zapata
{"title":"Trigeminal neuralgia secondary to minor size lesion, anatomical considerations and pathophysiology","authors":"Adrián Fernández García, Carlos Alberto Rodríguez Arias, Estefanía Utiel Monsálvez, Herbert Daniel Jiménez Zapata","doi":"10.1016/j.neucir.2024.11.002","DOIUrl":"10.1016/j.neucir.2024.11.002","url":null,"abstract":"<div><div>Trigeminal neuralgia is a well-characterized disorder of high prevalence among the current population. It may be caused, among many other causes, by a tumor which contacts with the trigeminal nerve, often of large volume. We present the case of a middle-aged woman without any remarkable medical background who suffered a trigeminal neuralgia caused by a subcentimeter tumor which appeared to be a meningioma. Some small tumors like this one may be symptomatic whereas larger ones will not. We discuss the pathogenesis and characterization of the trigeminal neuralgia in such cases proposing some mechanisms that could be involved in the development of a secondary neuralgia.</div></div>","PeriodicalId":51145,"journal":{"name":"Neurocirugia","volume":"36 3","pages":"Pages 204-207"},"PeriodicalIF":0.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143895901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NeurocirugiaPub Date : 2025-05-01DOI: 10.1016/j.neucir.2024.09.001
Kim Hoang , Jeffrey Santos , Areg Grigorian , Lourdes Swentek , Hansen Bow , Jeffry Nahmias
{"title":"Mortality risk factors for adult trauma patients treated with halo brace for cervical spine fracture","authors":"Kim Hoang , Jeffrey Santos , Areg Grigorian , Lourdes Swentek , Hansen Bow , Jeffry Nahmias","doi":"10.1016/j.neucir.2024.09.001","DOIUrl":"10.1016/j.neucir.2024.09.001","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>Halo braces treat upper cervical spine fractures and serve as the most rigid form of external immobilization. Recently, halo braces have lost favor due to known complications and advances in surgical stabilization. This study aims to determine the contemporary incidence for use of halo braces and identify risk factors associated with mortality in trauma patients undergoing halo brace for cervical spine fractures.</div></div><div><h3>Materials and methods</h3><div>The 2017–2019 Trauma Quality Improvement Program Database was queried for patients ≥18 years-old with a cervical spine fracture undergoing halo brace. Patients sustaining penetrating trauma and severe torso injuries (abbreviated injury scale >3 for the abdomen or thorax) were excluded. Bivariate and multivariable logistic regression analyses were performed.</div></div><div><h3>Results</h3><div>From 144,434 patients with a cervical spine fracture, 272 (0.2%) underwent halo brace and 14 (5%) of these died. Those who died were older (73.5 vs. 53 years-old, p = 0.011) and had higher rates of hypertension (78.6% vs 33.1%, p < 0.001) and chronic kidney disease (14.3% vs. 1.2%, p < 0.001). Glasgow Coma Scale ≤8 (46.2% vs. 8.2%, p < 0.001) and cervical spinal cord injury (71.4% vs. 21.3%, p < 0.001) were more common in patients who died. In addition, those who died more often sustained respiratory complications (7.1% vs. 0.4%, p = 0.004) and sepsis (7.1% vs. 0.4%, p = 0.004). On multivariable logistic regression analysis, only Glasgow Coma Scale ≤8 (OR 19.77, 3.04–128.45, p = 0.002) was associated with increased mortality.</div></div><div><h3>Conclusions</h3><div>Only 5% of cervical spine fracture patients undergoing halo brace died. Respiratory complications and sepsis were more common in those who died. On multivariable analysis only Glasgow Coma Scale ≤8 remained an independent associated risk factor for mortality.</div></div>","PeriodicalId":51145,"journal":{"name":"Neurocirugia","volume":"36 3","pages":"Pages 145-150"},"PeriodicalIF":0.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143896041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}