Noropsikiyatri Arsivi-Archives of Neuropsychiatry最新文献

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Turkish Validity and Reliability of Multidimensional Assessment of Interoceptive Awareness in Youth. 青年内感受意识多维度评估的土耳其语效度和信度。
IF 1 4区 医学
Noropsikiyatri Arsivi-Archives of Neuropsychiatry Pub Date : 2025-06-10 eCollection Date: 2025-01-01 DOI: 10.29399/npa.28855
Merve Onat, Dilek Konuksever, Hanife Avcı, Bahri Erdi Tanış, Esra Çöp, Gülser Şenses Dinç, Eda Özaydın
{"title":"Turkish Validity and Reliability of Multidimensional Assessment of Interoceptive Awareness in Youth.","authors":"Merve Onat, Dilek Konuksever, Hanife Avcı, Bahri Erdi Tanış, Esra Çöp, Gülser Şenses Dinç, Eda Özaydın","doi":"10.29399/npa.28855","DOIUrl":"10.29399/npa.28855","url":null,"abstract":"<p><strong>Introduction: </strong>Interoceptive awareness is defined as the processing of internal bodily signals and one's tendency to perceive these signals. In our study, it is aimed to conduct Turkish adaptation, reliability, and validity analysis of the Multidimensional Assessment of Interoceptive Awareness in Youth (MAIA-Y).</p><p><strong>Methods: </strong>275 young people between the ages of 11-17 participated in our study. Confirmatory factor analysis (CFA) was applied to confirm the factor structure of the Turkish version of MAIA-Y (MAIA-YT). Divergent validity was evaluated with Pearson correlation matrix plot. Internal consistency was determined using the \"Cronbach's alpha\" value. Paired sample t test or Wilcoxon test, Spearman's Correlation Coefficient, Intraclass Correlation Coefficient (ICC) value and Bland-Altman graphical approach were used to evaluate test-retest reliability. The significance value was set at a p-value of <0.05.</p><p><strong>Results: </strong>In our study, the fit measures are determined as χ<sup>2</sup>/df=1.612, CFI=0.898, GFI=0.869, TLI=0.882, IFI=0.901 and RMSEA=0.047, according to CFA. In accordance with the Pearson correlation matrix plot, there is a negative relationship between MAIA-YT subscales and State-Trait Anxiety Inventory for Children. The Cronbach's alpha coefficients for internal consistency were found to be between 0.303-0.792 for the subscales of MAIA-YT and 0.793 for the whole scale, and in general the MAIA-YT was found to have reliable internal consistency. Intraclass correlation coefficients for test-retest reliability were found between 0.515-0.731. According to the Bland Altman graphs, the agreement between the test-retest results was found to be at a reliable level.</p><p><strong>Conclusion: </strong>The MAIA-YT is a valid and reliable instrument for evaluation of interoceptive awareness in Turkish adolescents.</p>","PeriodicalId":51142,"journal":{"name":"Noropsikiyatri Arsivi-Archives of Neuropsychiatry","volume":"62 2","pages":"164-171"},"PeriodicalIF":1.0,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12205379/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144530997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Effect of Psychological Resilience on Treatment Compliance and Functionality in Patients with Bipolar Disorder. 心理弹性对双相情感障碍患者治疗依从性和功能的影响。
IF 1 4区 医学
Noropsikiyatri Arsivi-Archives of Neuropsychiatry Pub Date : 2025-06-10 eCollection Date: 2025-01-01 DOI: 10.29399/npa.28766
Mehmet Baltacıoğlu, Meltem Puşuroğlu
{"title":"The Effect of Psychological Resilience on Treatment Compliance and Functionality in Patients with Bipolar Disorder.","authors":"Mehmet Baltacıoğlu, Meltem Puşuroğlu","doi":"10.29399/npa.28766","DOIUrl":"10.29399/npa.28766","url":null,"abstract":"<p><strong>Introduction: </strong>Bipolar disorder (BD) is a serious psychiatric disorder that is common worldwide, and it is characterized by depressive and manic or hypomanic episodes. This study aimed to investigate the effect of psychological resilience on treatment adherence and functionality in patients diagnosed with BD.</p><p><strong>Methods: </strong>The sample of the study consisted of a total of 111 patients, 56 women and 55 men, who were followed up with a diagnosis of BD. A Sociodemographic and Clinical Characteristics Form, the Young Mania Rating Scale (YMRS), the Hamilton Depression Rating Scale (HDRS), the Resilience Scale for Adults (RSA), the Functioning Assessment Short Test (FAST), and the Morisky Medication Adherence Scale (MMAS) were used as data collection tools.</p><p><strong>Results: </strong>A significant negative relationship was found between the RSA scores and FAST scores of the patients (r<sub>s</sub>=-0.762; p<0.001). It was observed that resilience predicted functionality and treatment adherence. It was determined that each 1-unit increase in RSA scores caused a 0.021unit decrease in functionality scores (p<0.001). It was observed that each 1-unit increase in RSA total scores increased the probability of good treatment adherence by 1.336 times (p<0.001).</p><p><strong>Conclusion: </strong>In our study, it was observed that high psychological resilience had positive effects on functionality and treatment adherence in patients with BD.</p>","PeriodicalId":51142,"journal":{"name":"Noropsikiyatri Arsivi-Archives of Neuropsychiatry","volume":"62 2","pages":"136-144"},"PeriodicalIF":1.0,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12205383/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144530995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intrinsic Functional Connectivity Patterns of The Object-Selective Visual Areas. 对象选择性视觉区域的内在功能连接模式。
IF 1 4区 医学
Noropsikiyatri Arsivi-Archives of Neuropsychiatry Pub Date : 2025-06-08 eCollection Date: 2025-01-01 DOI: 10.29399/npa.28795
Ulaş Ay, Tamer Demiralp
{"title":"Intrinsic Functional Connectivity Patterns of The Object-Selective Visual Areas.","authors":"Ulaş Ay, Tamer Demiralp","doi":"10.29399/npa.28795","DOIUrl":"10.29399/npa.28795","url":null,"abstract":"<p><strong>Introduction: </strong>It has been shown by numerous investigations that the occipitotemporal area has a particular object perception area called the lateral occipital complex, which is composed of lateral occipital (LO) and posterior fusiform (pF) cortices. The aim of this study is to examine the intrinsic functional connectivity (iFC) patterns of the object-selective LO and pF regions in order to shed light on the underlying neural mechanisms of object recognition.</p><p><strong>Methods: </strong>15 healthy participants were included in the study. A standard localizer task was used to identify LO and pF regions. Magnetic resonance imaging (MRI) data were collected using two different imaging protocols: high-resolution anatomical image and functional MRI (fMRI) data. Data preprocessing steps were carried out in accordance with standard procedures. After determining the LO and pF regions with activation analyses on the task-based fMRI data, the iFCs of these regions were investigated with functional connectivity analyses carried out on the resting-state fMRI recording.</p><p><strong>Results: </strong>iFC analyzes revealed that LO and pF regions have different connectivity patterns. Lateral occipital had a widely distributed connectivity network, whereas pF showed a more localized connectivity pattern. Lateral occipital had more extensive occipitotemporal, occipitoparietal and motor connections compared to pF. In contrast to this distribution pattern, the connections of the right and left LO were generally concentrated on the ipsilateral sides, while the connections of the pF were bilateral.</p><p><strong>Conclusion: </strong>The results of the study revealed complex iFC patterns of the LO and pF differentiating their functional roles in object perception/recognition. While the pF revealed bilaterally distributed iFC along the ventral visual stream, the extensive and lateralized iFC of the LO suggests its role in integrating visual information including object-related attention and action recognition.</p>","PeriodicalId":51142,"journal":{"name":"Noropsikiyatri Arsivi-Archives of Neuropsychiatry","volume":"62 2","pages":"100-108"},"PeriodicalIF":1.0,"publicationDate":"2025-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12205391/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144530938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Case of Distal Hereditary Motor Neuropathy with HSPB1 Mutation in Coexistence with Myotonia and Myopathy. 远端遗传性运动神经病伴HSPB1突变并发肌强直和肌病1例。
IF 1 4区 医学
Noropsikiyatri Arsivi-Archives of Neuropsychiatry Pub Date : 2025-06-08 eCollection Date: 2025-01-01 DOI: 10.29399/npa.28654
Handan Uzunçakmak-Uyanık, Ersin Tan, Çağrı Mesut Temuçin
{"title":"A Case of Distal Hereditary Motor Neuropathy with HSPB1 Mutation in Coexistence with Myotonia and Myopathy.","authors":"Handan Uzunçakmak-Uyanık, Ersin Tan, Çağrı Mesut Temuçin","doi":"10.29399/npa.28654","DOIUrl":"10.29399/npa.28654","url":null,"abstract":"<p><p>Distal hereditary motor neuropathies (dHMNs), also named as distal spinal muscular atrophy, are a group of disorders that cause degeneration of motor nerves. Currently, only 15% to 32.5% of patients with dHMN have been genetically identified. The most common cause of dHMNs gene mutations is HSPB1 mutation. In HSPB1 mutation, which is also one of the myopathogens via satellite cell pathology, dHMNS may coexist with neuromuscular junction disorder, motor neuron disease, satellite cell dysfunction and therefore myopathic findings. No case of myopathy and myotonia with HSPB1 mutation has been reported in the literature yet. We present a case with electrophysiologic findings in HSPB1 mutation by discussing the possible mechanisms underlying myotonic discharges and myopathic findings.</p>","PeriodicalId":51142,"journal":{"name":"Noropsikiyatri Arsivi-Archives of Neuropsychiatry","volume":"62 2","pages":"205-206"},"PeriodicalIF":1.0,"publicationDate":"2025-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12205387/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144530933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Parietal Cortex Volume and Functions in Major Depression and Bipolar Disorder: A Cloud-Based Magnetic Resonans Imaging Study. 重度抑郁症和双相情感障碍的顶叶皮质体积和功能:基于云的磁共振成像研究。
IF 1 4区 医学
Noropsikiyatri Arsivi-Archives of Neuropsychiatry Pub Date : 2025-02-26 eCollection Date: 2024-01-01 DOI: 10.29399/npa.28253
Fatma Kiliç, Fatma Kartal, Mehmet Fatih Erbay, Rıfat Karlidağ
{"title":"Parietal Cortex Volume and Functions in Major Depression and Bipolar Disorder: A Cloud-Based Magnetic Resonans Imaging Study.","authors":"Fatma Kiliç, Fatma Kartal, Mehmet Fatih Erbay, Rıfat Karlidağ","doi":"10.29399/npa.28253","DOIUrl":"10.29399/npa.28253","url":null,"abstract":"<p><strong>Introduction: </strong>The present study aimed to compare the Parietal Lobe (PL) volumes and Cancellation Test (CT) performances of euthymic patients with Bipolar Disorder-1 (BD) and Major Depressive Disorder (MDD), and healthy controls.</p><p><strong>Methods: </strong>The present study included 63 participants in three groups; two patient groups in remission involving patients with BD and MDD diagnosed according to DSM-5 and a control group with healthy individuals. Sociodemographic Data Form, CT, and Hand Preference Questionnaire were applied to all participants. Participant PL volumes were measured with the Cloud-Based Brain Magnetic Resonance Image Segmentation - Parcellation System.</p><p><strong>Results: </strong>Both patient groups exhibited lower PL volume when compared to the control group, and there was no difference between the patient groups based on PL volume. It was determined that MDD and BB patients scored less in the CT when compared to the control group. There was a weak correlation between right and left PL volumes and CT performances.</p><p><strong>Conclusion: </strong>The present study findings demonstrated that BD and MDD patients in remission exhibited lower PL volume and CT performance when compared to healthy controls, emphasizing that PL could be structurally and functionally significant in the pathophysiology of mood disorders.</p>","PeriodicalId":51142,"journal":{"name":"Noropsikiyatri Arsivi-Archives of Neuropsychiatry","volume":"14 1","pages":"47-54"},"PeriodicalIF":1.0,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10943943/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85241498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Autoimmune Etiologies with The Potential to Transform Psychiatric Practice: Experiences from a Neuropsychiatry Unit. 自身免疫性病因与潜在的转变精神病学实践:经验从神经精神病学单位。
IF 1 4区 医学
Noropsikiyatri Arsivi-Archives of Neuropsychiatry Pub Date : 2025-02-20 eCollection Date: 2025-01-01 DOI: 10.29399/npa.29053
Rifat Serav İlhan, Berker Duman
{"title":"Autoimmune Etiologies with The Potential to Transform Psychiatric Practice: Experiences from a Neuropsychiatry Unit.","authors":"Rifat Serav İlhan, Berker Duman","doi":"10.29399/npa.29053","DOIUrl":"10.29399/npa.29053","url":null,"abstract":"","PeriodicalId":51142,"journal":{"name":"Noropsikiyatri Arsivi-Archives of Neuropsychiatry","volume":"62 1","pages":"1-2"},"PeriodicalIF":1.0,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11877387/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143568708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Role of Resolvin D1 in Indicating Chronic Inflammation and Axonal Damage in Bipolar Disorder: A Comparative Study of Manic and Depressive Episodes. Resolvin D1在双相情感障碍慢性炎症和轴突损伤中的指示作用:躁狂和抑郁发作的比较研究
IF 1 4区 医学
Noropsikiyatri Arsivi-Archives of Neuropsychiatry Pub Date : 2025-02-20 eCollection Date: 2025-01-01 DOI: 10.29399/npa.28891
Burcu Kök Kendirlioğlu, Özge Yüksel Öksüz, Tevfik Kalelioğlu, Şule Sözen, Pelin Ünalan Özperçin, Refik Cihnioğlu, Nesrin Karamustafalıoğlu
{"title":"The Role of Resolvin D1 in Indicating Chronic Inflammation and Axonal Damage in Bipolar Disorder: A Comparative Study of Manic and Depressive Episodes.","authors":"Burcu Kök Kendirlioğlu, Özge Yüksel Öksüz, Tevfik Kalelioğlu, Şule Sözen, Pelin Ünalan Özperçin, Refik Cihnioğlu, Nesrin Karamustafalıoğlu","doi":"10.29399/npa.28891","DOIUrl":"10.29399/npa.28891","url":null,"abstract":"<p><strong>Introduction: </strong>Bipolar disorder (BD) is a chronic disorder associated with significant psychiatric morbidity and disability. Recent research has linked inflammatory processes to the pathology of BD. Resolvin D1 (RvD1), an anti-inflammatory molecule derived from eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), has been shown to inhibit apoptosis and neuroinflammation, and promote neurogenesis. This study aims to determine changes in serum RvD1 levels between acute episode and euthymic periods in patients with BD and their association with inflammatory and metabolic syndrome (MetS) parameters.</p><p><strong>Methods: </strong>This prospective clinical study was conducted with patients diagnosed with BD-I according to SCID-5. Patients whose serum RvD1 levels were assessed during manic and depressive episodes in the previous study were invited to return to the study after at least 8 weeks, when they had reached the euthymic period. Blood samples for RvD1, C-reactive protein (CRP), and hemogram tests were collected during both acute episodes and remission periods.</p><p><strong>Results: </strong>The study included 32 patients in manic episodes, 27 in depressive episodes, and 41 healthy controls, with no significant age difference among the groups. RvD1 levels decreased significantly from manic episodes to complete remission period (p=0.017, z=-2.391) during follow-up. The decrease from depression to remission was not statistically significant. Serum RvD1 levels in patients with depressive episodes in remission remained high in the control group (p=0.581, z=-0.553). During the follow-up period, white blood cell (p=0.009, z=-2.606) and neutrophil (p=0.007, z=-2.693) in mania period and CRP values in depression period (p=0.004, z=-2.880) were found to have decreased statistically.</p><p><strong>Conclusions: </strong>The study indicates that serum RvD1 levels are elevated during manic and depressive episodes in BD patients compared to healthy controls and decrease significantly during the remission period in patients with manic episode. We propose the potential utility of RvD1 as a diagnostic marker for identifying manic and depressive states. We can assume that there is an inflammatory process in BD in which RvD1 also plays a role. Further research is needed to explore the therapeutic potential of targeting RvD1 pathways in BD treatment.</p>","PeriodicalId":51142,"journal":{"name":"Noropsikiyatri Arsivi-Archives of Neuropsychiatry","volume":"62 1","pages":"3-10"},"PeriodicalIF":1.0,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11877384/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143568688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
CADASIL Syndrome Presenting as Obsessive-Compulsive Disorder: A Case Report. 表现为强迫症的 CADASIL 综合征:病例报告。
IF 1 4区 医学
Noropsikiyatri Arsivi-Archives of Neuropsychiatry Pub Date : 2025-02-20 eCollection Date: 2025-01-01 DOI: 10.29399/npa.28683
Derya Canlı, Mesut Keskin
{"title":"CADASIL Syndrome Presenting as Obsessive-Compulsive Disorder: A Case Report.","authors":"Derya Canlı, Mesut Keskin","doi":"10.29399/npa.28683","DOIUrl":"10.29399/npa.28683","url":null,"abstract":"<p><p>Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL) is a small vessel disease. It is an autosomal dominant inherited disease caused by a mutation in the Notch3 gene. Clinically, it usually presents with recurrent transient ischemic attacks, strokes, vascular dementia, migraine with aura, cognitive impairments and psychiatric symptoms. Cranial MRI is the most useful imaging modality to demonstrate the characteristic radiological findings of CADASIL and gene analysis is the gold standard for diagnosis. Although the clinical manifestations are mainly neurological, CADASIL can also present with psychiatric disorders. Psychiatric disorders are one of the main clinical manifestations of the disease, with a prevalence rate ranging from 20 to 41%. Among psychiatric disorders, mood disorders are the most commonly reported, and other psychiatric diagnoses include psychotic disorders, anxiety disorders, adjustment disorder, personality disorders, behavioral disorders, substance dependence and abuse. In this case report, a paitent with CADASIL presenting with obsessive-compulsive disorder at a relatively young age will be presented.</p>","PeriodicalId":51142,"journal":{"name":"Noropsikiyatri Arsivi-Archives of Neuropsychiatry","volume":"62 1","pages":"90-93"},"PeriodicalIF":1.0,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11877385/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143568710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Idiopathic Parkinson's Disease and Neuro-ophthalmological Findings: A Study on Neurodegeneration in the Retinal Nerve Fiber Layer and Cognitive Functions. 特发性帕金森氏病和神经眼科的发现:视网膜神经纤维层神经变性和认知功能的研究。
IF 1 4区 医学
Noropsikiyatri Arsivi-Archives of Neuropsychiatry Pub Date : 2025-02-20 eCollection Date: 2025-01-01 DOI: 10.29399/npa.28670
Sibel Çekiç, Bilge Piri Çınar, Esra Acıman Demirel, Mehmet Orçun Akdemir, Ulufer Çelebi, Mustafa Açıkgöz, Hüseyin Tuğrul Atasoy
{"title":"Idiopathic Parkinson's Disease and Neuro-ophthalmological Findings: A Study on Neurodegeneration in the Retinal Nerve Fiber Layer and Cognitive Functions.","authors":"Sibel Çekiç, Bilge Piri Çınar, Esra Acıman Demirel, Mehmet Orçun Akdemir, Ulufer Çelebi, Mustafa Açıkgöz, Hüseyin Tuğrul Atasoy","doi":"10.29399/npa.28670","DOIUrl":"10.29399/npa.28670","url":null,"abstract":"<p><strong>Introduction: </strong>This study was designed to explore the relationship between retinal nerve fiber layer (RNFL) thickness and cognition in Idiopathic Parkinson's disease (IPD) patients without visual symptoms or diagnosis of dementia.</p><p><strong>Methods: </strong>Groups of patients with idiopathic Parkinson's disease and healthy controls were compared ophthalmologically using optical coherence tomography (OCT) and cognitively through neuropsychological tests.</p><p><strong>Results: </strong>The findings highlighted a pronounced RNFL thinning, especially in the right nasal inferior quadrant of IPD patients compared to the control group. Almost half (47%) of the subjects in the IPD group exhibited issues in one or multiple subcomponents of Addenbrooke's Cognitive Examination-Revised (ACE-R). At the same time, the study suggested that effects in the visuospatial domain may be associated with disease severity in IPD patients. However, the investigation could not establish a direct association between the severity or duration of the disease and OCT measurements. A correlation was observed between certain ACE-R scores and some RNFL quadrants.</p><p><strong>Conclusion: </strong>In conclusion, the inception phases of IPD are characterized by discernable visual pathologies and cognitive anomalies. The thinning of the RNFL, which can be identified through OCT, might serve as a pivotal tool for tracking the early progression of IPD and formulating intervention strategies. That being said, more comprehensive studies are essential to wholly understand OCT's role in the early diagnosis and monitoring of IPD.</p>","PeriodicalId":51142,"journal":{"name":"Noropsikiyatri Arsivi-Archives of Neuropsychiatry","volume":"62 1","pages":"77-83"},"PeriodicalIF":1.0,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11877375/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143568723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Decision Making, Emotion Recognition and Childhood Traumatic Experiences in Murder Convicts Imprisoned with Aggravated Life Sentence: A Prison Study. 谋杀犯加重无期徒刑监禁的决策、情绪识别与童年创伤经历:监狱研究。
IF 1 4区 医学
Noropsikiyatri Arsivi-Archives of Neuropsychiatry Pub Date : 2025-02-20 eCollection Date: 2025-01-01 DOI: 10.29399/npa.28778
Uğur Çıkrıkçılı, Elif Yıldırım, Seda Buker, Can Ger, Ozan Erözden, Hakan Gürvit, Bilgin Saydam
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