International Journal of Eating Disorders最新文献

{"title":"Assessing Severity in Anorexia Nervosa Using Alternative Criteria to the DSM-5 in a Cross-Sectional Study.","authors":"Esther Henriet, Joanna Norton, Maude Seneque, Laurent Maimoun, Philippe Courtet, Sébastien Guillaume","doi":"10.1002/eat.24542","DOIUrl":"https://doi.org/10.1002/eat.24542","url":null,"abstract":"<p><strong>Objective: </strong>This study compared overvaluation of weight and shape (OWS), drive for thinness (DT), and their combination (OWS-DT) as alternative severity classifications for anorexia nervosa (AN) to the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) severity classification.</p><p><strong>Method: </strong>312 AN treatment-seeking outpatients (mean age = 26.8, SD = 10.2, mean body mass index = 17.3, SD = 2.4) were classified using BMI-based DSM-5 criteria (mild/moderate/severe/extreme), OWS (no/yes), DT (no/yes), and OWS-DT combination (neither/one or the other/both). These classifications were evaluated based on associations with clinical and functional severity indicators, including psychiatric comorbidities, psychopathology via the Eating Disorder Examination Questionnaire and the Eating Disorder Inventory, functional impairment via the Eating Disorders Quality-of-Life Questionnaire and Work-and-Social Adjustment Scale, and biological markers.</p><p><strong>Results: </strong>OWS and DT separately were strongly and positively associated with psychiatric comorbidities, psychopathology, and functional impairment. Severity increased across OWS-DT groups, distinguishing mild (neither), moderate (mainly OWS), and severe (both OWS and DT). DT rarely appeared without OWS. DSM-5 classification alone had limited clinical relevance, primarily reflecting restriction of energy intake. No significant differences emerged across severity classifications for biological markers.</p><p><strong>Discussion: </strong>Findings offer limited support for DSM-5 severity criteria alone. OWS and DT showed clearer clinical utility, with the OWS-DT combination more effectively identifying severity. A stepwise model-screening for OWS followed by DT assessment-may best capture severity in clinical settings.</p>","PeriodicalId":51067,"journal":{"name":"International Journal of Eating Disorders","volume":" ","pages":""},"PeriodicalIF":4.3,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145030888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Issue Information: Editorial Board & Table of Contents","authors":"","doi":"10.1002/eat.24544","DOIUrl":"https://doi.org/10.1002/eat.24544","url":null,"abstract":"","PeriodicalId":51067,"journal":{"name":"International Journal of Eating Disorders","volume":"58 9","pages":"1607-1608"},"PeriodicalIF":4.3,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/eat.24544","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145037563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Light and Shadow of Smartphone Applications for Eating Disorders: Commentary on Cruz et al. (2025).","authors":"Silvia Cerea","doi":"10.1002/eat.24536","DOIUrl":"https://doi.org/10.1002/eat.24536","url":null,"abstract":"<p><p>Smartphone applications (apps) represent promising tools to overcome common barriers to treatment in individuals within the Eating Disorders (EDs) spectrum, thanks to their constant availability and cost-effectiveness. In this context, Cruz et al. (2025) conducted the first meta-analysis of randomized controlled trials (RCTs) evaluating the efficacy of app-based interventions for EDs. Their findings provided evidence supporting the use of app-based interventions over control conditions in reducing ED symptoms and risk factors, although effect sizes were generally small. Despite these promising findings, caution is needed due to methodological concerns in the included trials, such as limited sample diversity, inconsistent follow-up durations, and the frequent use of waitlist controls. Notably, no significant effects were observed for key ED dimensions such as body dissatisfaction/disturbance and drive for thinness, pointing to the need for interventions grounded in robust body image theory and frameworks. Furthermore, the current evidence does not adequately address the efficacy of these apps across different populations, including adolescents, gender-diverse individuals, and those from varied racial, ethnic, and socioeconomic backgrounds. To maximize the clinical utility of these tools, future research should prioritize methodologically rigorous trials, adopt inclusive and intersectional frameworks, and expand evaluative outcomes beyond symptom reduction to include multiple indicators of psychological flourishing. These directions are essential to unlock the full potential of app-based interventions for EDs across diverse populations.</p>","PeriodicalId":51067,"journal":{"name":"International Journal of Eating Disorders","volume":" ","pages":""},"PeriodicalIF":4.3,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145024760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Conducting Eating Disorder Research in the Era of Generative AI: Researcher Perspectives and Guidelines From the International Journal of Eating Disorders.","authors":"Jake Linardon, Jennifer J Thomas, Scott J Crow, Ata Ghaderi, Anja Hilbert, Kelly L Klump, Tracey D Wade, B Timothy Walsh, Ruth Weissman","doi":"10.1002/eat.24543","DOIUrl":"https://doi.org/10.1002/eat.24543","url":null,"abstract":"<p><strong>Objectives: </strong>Generative Artificial Intelligence (AI) could transform how science is conducted, supporting researchers with writing, coding, peer review, and evidence synthesis. However, it is not yet known how eating disorder researchers utilize generative AI, and uncertainty remains regarding its safe, ethical, and transparent use. The Executive Committee of the International Journal of Eating Disorders disseminated a survey for eating disorder researchers investigating their practices and perspectives on generative AI, with the goal of informing guidelines on appropriate AI use for authors, reviewers, and editors.</p><p><strong>Method: </strong>A survey was distributed globally via eating disorder organizations, professional networks, and individual researchers. Researchers (N = 158) of various career stages completed the survey.</p><p><strong>Results: </strong>Nearly three-quarters (70%) reported using generative AI for research, most commonly for proofreading written work or coding support. Nine in 10 took steps to verify AI-generated output, and 1 in 3 disclosed their use of AI. Only 21% reported using AI for peer review, typically in a limited capacity (e.g., proofreading), and always with full human oversight. Authors were comfortable for editors to use AI to support administrative tasks (i.e., selecting reviewers, detecting plagiarism). However, many participants acknowledged key drawbacks of generative AI, including concerns about inaccurate outputs, ethical issues such as plagiarism, the potential for reduced critical thinking, and anticipated negative impacts on the future of eating disorder research.</p><p><strong>Conclusion: </strong>These insights informed the development of field-specific guidelines to support authors, reviewers, and editors in the appropriate use of generative AI in eating disorder research and publishing.</p>","PeriodicalId":51067,"journal":{"name":"International Journal of Eating Disorders","volume":" ","pages":""},"PeriodicalIF":4.3,"publicationDate":"2025-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145016584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Toward a Genetic Signature of Resistance to Activity-Based Anorexia in Striatal Projecting Cortical Neurons.","authors":"K Huang, M A Magateshvaren Saras, K Conn, E Greaves, F Reed, S Tyagi, H Munguba, C J Foldi","doi":"10.1002/eat.24538","DOIUrl":"https://doi.org/10.1002/eat.24538","url":null,"abstract":"<p><strong>Objective: </strong>Converging evidence from neuroimaging studies and genome-wide association study (GWAS) suggests the involvement of prefrontal cortex (PFC) and striatum dysfunction in the pathophysiology of anorexia nervosa (AN). However, identifying the causal role of circuit-specific genes in the development of the AN-like phenotype remains challenging and requires the combination of novel molecular tools and preclinical models.</p><p><strong>Methods: </strong>We used the activity-based anorexia (ABA) rat model in combination with a novel viral-based translating ribosome affinity purification (TRAP) technique to identify transcriptional differences within a specific neural pathway that we have previously demonstrated to mediate pathological weight loss in ABA rats (i.e., medial PFC neurons that project to the nucleus accumbens shell). We compared actively transcribed genes in rats susceptible to weight loss to the subpopulation of rats resistant to weight loss under the same experimental conditions.</p><p><strong>Results: </strong>We reveal 1424 differentially expressed genes between Susceptible and Resistant rats, highlighting important transcriptional changes associated with ABA within this pathway. The changes observed were independent of current calorie deficit and associated with metabolic, mitochondrial, and neural functions. Further, we show that genes upregulated in Resistant rats were involved in mitochondrial function, while downregulated genes were associated with cytoskeletal, postsynaptic, and axonal functions, supporting the hypothesis that hyperexcitability of cortico-striatal circuit function is a critical mediator of pathological weight loss in ABA.</p><p><strong>Discussion: </strong>These findings represent an essential first step in understanding how circuit-specific gene expression patterns may contribute to susceptibility to ABA and provide potential molecular targets for manipulation in this animal model of AN.</p><p><strong>Public significance: </strong>This study identifies specific brain gene activity patterns that may explain why some individuals are more vulnerable to extreme weight loss, as seen in AN. Using an advanced molecular technique in a well-established animal model, key differences in a neural pathway linked to cognitive control were observed. These findings pave the way for more targeted treatments that could prevent or reverse this dangerous condition.</p>","PeriodicalId":51067,"journal":{"name":"International Journal of Eating Disorders","volume":" ","pages":""},"PeriodicalIF":4.3,"publicationDate":"2025-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145006866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of Remote Family Education and Support Program for Parents of Adolescents With Eating Disorders Based on Interpersonal Psychotherapy: A Randomized Controlled Trial.","authors":"Fujika Katsuki, Hanayo Sawada, Yuka Kawasaki, Masaki Kondo, Atsurou Yamada, Norio Watanabe","doi":"10.1002/eat.24541","DOIUrl":"https://doi.org/10.1002/eat.24541","url":null,"abstract":"<p><strong>Objective: </strong>Given the frequent conflict between parents and adolescents with eating disorders, we aimed to develop a remote family education and support program (rFESP) for parents based on the principles of interpersonal psychotherapy (IPT) and investigate its effect on promoting effective communication at home.</p><p><strong>Method: </strong>A clinical trial involving 67 parents of patients with adolescent eating disorders was conducted. Participants were randomly assigned to either the rFESP intervention group or the waiting control group. The intervention group received four rFESP sessions of 150 min each, conducted weekly over 4 weeks. Specifically, the primary outcome was the change in parents' active listening ability, as measured by the Active Listening Attitude Scale, while the secondary outcome was the change in the perception of social support and eating disorder symptoms evaluated by parents. Intention-to-treat analyses were conducted.</p><p><strong>Results: </strong>A statistically significant effect of rFESP was found on the Active Listening Attitude Scale at 8 weeks (mean difference: 3.68, 95% confidence interval: 1.89-5.48, p < 0.001). Similarly, the intervention group scored higher with regard to perceived social support (difference = 2.69, 95% confidence interval: 1.11-4.27, p < 0.001). No significant differences were found in eating disorder symptoms.</p><p><strong>Discussion: </strong>To the best of our knowledge, this is the first study to evaluate the effectiveness of an IPT-based program for parents of adolescents with eating disorders. These findings suggest that this type of intervention is effective, albeit indirect, and could be a new support method for adolescent patients and their parents.</p><p><strong>Trial registration: </strong>Clinical Trials.gov ID: NCT05840614.</p>","PeriodicalId":51067,"journal":{"name":"International Journal of Eating Disorders","volume":" ","pages":""},"PeriodicalIF":4.3,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144977402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Feasibility and Acceptability of Brief Behavioral Treatment for Insomnia After Eating Disorder Treatment: The TIRED Study.","authors":"Kara A Christensen Pacella, Angeline R Bottera, Kelsie T Forbush, Jaelin Isquith, Kyle De Young","doi":"10.1002/eat.24540","DOIUrl":"10.1002/eat.24540","url":null,"abstract":"<p><strong>Objective: </strong>The purpose of this pilot trial was to evaluate the novel use of Brief Behavioral Treatment for Insomnia (BBTI) for people with residual insomnia disorder following eating disorder (ED) treatment.</p><p><strong>Methods: </strong>Participants (N = 6) completed a multiple-baseline design study of BBTI. The primary outcome was insomnia severity, measured by the Insomnia Severity Index. Secondary outcomes included sleep efficiency and daytime fatigue. Exploratory outcomes were ED-related impairment and symptoms, anxiety symptoms, and depression symptoms.</p><p><strong>Results: </strong>BBTI reduced insomnia symptom severity from baseline to end of treatment. BBTI also resulted in improvements in sleep efficiency and reductions in daytime fatigue. ED-related and other psychopathology outcomes largely did not change.</p><p><strong>Discussion: </strong>BBTI showed preliminary evidence of efficacy, acceptability, and feasibility among people with residual insomnia following ED treatment. Future studies should use randomized controlled designs to better elicit the effects of BBTI on ED-related outcomes.</p>","PeriodicalId":51067,"journal":{"name":"International Journal of Eating Disorders","volume":" ","pages":""},"PeriodicalIF":4.3,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12462618/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144977478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"\"In Their Own Words\": A Qualitative Exploration of Lived Experience and Healthcare Professional Perspectives on Evaluating a Digital Intervention for Binge Eating.","authors":"Rebecca Murphy, Emma L Osborne, Nikki Newhouse, John Powell","doi":"10.1002/eat.24539","DOIUrl":"https://doi.org/10.1002/eat.24539","url":null,"abstract":"<p><strong>Objective: </strong>Eating disorders characterized by binge eating are prevalent yet under-recognized, limiting access to effective care. The digital, programme-led (self-help) version of Enhanced Cognitive Behavior Therapy (CBT-E) offers a potentially scalable treatment. This study gathered insights from individuals with lived experience of binge eating (LE) and healthcare professionals (HCPs) to inform the design of a randomized controlled trial evaluating the intervention's effectiveness and to support early-stage implementation planning.</p><p><strong>Method: </strong>Four focus groups were conducted with 20 participants (8 with LE, 12 HCPs). Discussions explored recruitment strategies, participant engagement, meaningful outcome measures, and barriers to implementation. Data were analyzed using thematic analysis.</p><p><strong>Results: </strong>Two overarching themes were identified: (1) Reach People in Accessible and Supportive Ways, and (2) Be Open to Different Experiences of Progress. Participants emphasized inclusive recruitment and compassionate, hopeful messaging. Stigma and limited recognition of binge eating were cited as recruitment barriers in healthcare settings. Both groups recommended community and online platforms to enhance reach. Participants stressed the importance of outcomes beyond symptom reduction (e.g., emotional well-being) and qualitative methods to capture recovery narratives. Findings also highlighted implementation-relevant factors, including how interventions are framed and delivered, and how engagement can be optimized.</p><p><strong>Discussion: </strong>Perspectives from individuals with LE and HCPs support a person-centred trial aligned with the needs of those experiencing binge eating and those providing care, while considering both evaluative and implementation priorities. Findings inform strategies to enhance reach and understanding of digital intervention outcomes, contributing to trial designs that are consistent with real-world care and meaningful to participants.</p>","PeriodicalId":51067,"journal":{"name":"International Journal of Eating Disorders","volume":" ","pages":""},"PeriodicalIF":4.3,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144977812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"From Promise to Precision: Future Directions for Smartphone Application Eating Disorder Interventions-Commentary on Cruz et al. (2025).","authors":"Mariel Messer","doi":"10.1002/eat.24537","DOIUrl":"https://doi.org/10.1002/eat.24537","url":null,"abstract":"<p><p>Despite growing interest in smartphone applications (apps) as tools for eating disorder (ED) intervention, significant challenges remain in optimizing their utility and implementation. Cruz et al. conducted a meta-analysis of 14 trials examining smartphone app-based interventions for EDs, finding apps to effectively reduce numerous symptoms. While their findings highlight the promise of app-based interventions for symptom management, realizing their full potential will require a shift toward enhancing their potency, personalization, and flexible delivery. This commentary proposes three critical areas for future research in apps within the context of ED care. First, there is a pressing need to transition from static to adaptive systems that tailor support based on real-time, continuously collected active, passive, and metadata. Second, greater consideration should be given to how apps are best deployed, whether through established or novel models of care. Third, outcome variability points to a need for precision-focused research to better identify who benefits most from app-based interventions, ideally leveraging complex data-driven approaches that model clinical, behavioral, and engagement data. Together, these directions chart a pathway toward more intelligent, responsive, and equitable app-based tools for EDs.</p>","PeriodicalId":51067,"journal":{"name":"International Journal of Eating Disorders","volume":" ","pages":""},"PeriodicalIF":4.3,"publicationDate":"2025-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144977545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rigid Minds: The Role of Obsessive-Compulsive Personality Traits in Anorexia Nervosa.","authors":"Caroline E Touzeau, Alexandra Allam, Alexandra F Muratore, Evelyn Attia, Joanna E Steinglass","doi":"10.1002/eat.24532","DOIUrl":"10.1002/eat.24532","url":null,"abstract":"<p><strong>Objective: </strong>Restrictive eating behavior in anorexia nervosa (AN) is often characterized by rigidity, dichotomous thinking, and cognitive inflexibility. These traits are also central to obsessive-compulsive personality disorder (OCPD). The current study assessed whether OCPD traits among patients with AN were associated with the severity of illness or short-term treatment outcome.</p><p><strong>Method: </strong>Presence of OCPD traits were measured among hospitalized adults and adolescents as well as healthy peers (HC), using the Pathological Obsessive Compulsive Personality Scale (POPS). In addition to comparing groups, patients with AN were assessed before and after weight restoration treatment to examine changes with renourishment. Associations between POPS and other indices of clinical severity were tested.</p><p><strong>Results: </strong>POPS scores were significantly higher among AN (n = 208) than HC (n = 124) (Total: 173.2 ± 33.4 vs. 132.3 ± 32.6, t₃₃₀ = 10.9, p < 0.001), across all five domains (Rigidity, Emotional Overcontrol, Maladaptive Perfectionism, Reluctance to Delegate, Difficulty with Change). Among AN, higher POPS scores were positively associated with EDE-Q (r₁₉₅ = 0.29, p = < 0.001) and YBC-EDS scores (r₂₀₁ = 0.28, p = < 0.001). POPS scores did not change with weight restoration and were not significantly associated with treatment outcome.</p><p><strong>Discussion: </strong>OCPD personality traits were elevated among individuals with AN, though scores were lower than populations with OCPD. These traits did relate to illness severity, but not to treatment outcome. While these traits may merit attention in treatment, co-occurring OCPD may not be central to the kind of rigidity that perpetuates AN.</p>","PeriodicalId":51067,"journal":{"name":"International Journal of Eating Disorders","volume":" ","pages":""},"PeriodicalIF":4.3,"publicationDate":"2025-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12439244/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144977619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}