International Journal of Eating Disorders最新文献

{"title":"Medical Comorbidities, Nutritional Markers, and Cardiovascular Risk Markers in Youth With ARFID","authors":"Helen Burton-Murray,&nbsp;Aluma Chovel Sella,&nbsp;Julia E. Gydus,&nbsp;Micaela Atkins,&nbsp;Lilian P. Palmer,&nbsp;Megan C. Kuhnle,&nbsp;Kendra R. Becker,&nbsp;Lauren E. Breithaupt,&nbsp;Kathryn S. Brigham,&nbsp;Anna Aulinas,&nbsp;Kyle Staller,&nbsp;Kamryn T. Eddy,&nbsp;Madhusmita Misra,&nbsp;Nadia Micali,&nbsp;Jennifer J. Thomas,&nbsp;Elizabeth A. Lawson","doi":"10.1002/eat.24243","DOIUrl":"10.1002/eat.24243","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>Avoidant/restrictive food intake disorder (ARFID) is common among populations with nutrition-related medical conditions. Less is known about the medical comorbidity/complication frequencies in youth with ARFID. We evaluated the medical comorbidities and metabolic/nutritional markers among female and male youth with full/subthreshold ARFID across the weight spectrum compared with healthy controls (HC).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Method</h3>\u0000 \u0000 <p>In youth with full/subthreshold ARFID (<i>n</i> = 100; 49% female) and HC (<i>n</i> = 58; 78% female), we assessed self-reported medical comorbidities via clinician interview and explored abnormalities in metabolic (lipid panel and high-sensitive C-reactive protein [hs-CRP]) and nutritional (25[OH] vitamin D, vitamin B12, and folate) markers.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Youth with ARFID, compared with HC, were over 10 times as likely to have self-reported gastrointestinal conditions (37% vs. 3%; OR = 21.2; 95% CI = 6.2–112.1) and over two times as likely to have self-reported immune-mediated conditions (42% vs. 24%; OR = 2.3; 95% CI = 1.1–4.9). ARFID, compared with HC, had a four to five times higher frequency of elevated triglycerides (28% vs. 12%; OR = 4.0; 95% CI = 1.7–10.5) and hs-CRP (17% vs. 4%; OR = 5.0; 95% CI = 1.4–27.0) levels.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Discussion</h3>\u0000 \u0000 <p>Self-reported gastrointestinal and certain immune comorbidities were common in ARFID, suggestive of possible bidirectional risk/maintenance factors. Elevated cardiovascular risk markers in ARFID may be a consequence of limited dietary variety marked by high carbohydrate and sugar intake.</p>\u0000 </section>\u0000 </div>","PeriodicalId":51067,"journal":{"name":"International Journal of Eating Disorders","volume":"57 11","pages":"2167-2175"},"PeriodicalIF":4.7,"publicationDate":"2024-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141472320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}