Clinical Biomechanics最新文献

{"title":"Cognitive-motor dual task to reveal gait impairments in multiple sclerosis patients at an early stage: A systematic review","authors":"David Péron ,&nbsp;Sébastien Leteneur ,&nbsp;Bruno Lenne ,&nbsp;Ghassan Ido ,&nbsp;Cécile Donzé ,&nbsp;Franck Barbier ,&nbsp;Caroline Massot","doi":"10.1016/j.clinbiomech.2024.106300","DOIUrl":"10.1016/j.clinbiomech.2024.106300","url":null,"abstract":"<div><h3>Background</h3><p>Multiple sclerosis can cause locomotor and cognitive impairments even at lower levels of disability, which can impact daily life. The cognitive-motor dual task is commonly used to assess everyday locomotion. Thus, this study aimed to examine the effect of cognitive-motor dual tasks on gait parameters among patients with multiple sclerosis in the early disease stages and to determine whether dual tasks could be used as a clinical test to detect locomotion impairments.</p></div><div><h3>Methods</h3><p>A systematic search of five databases was conducted in May 2024. The population of interest was patients with multiple sclerosis with an Expanded Disability Status Scale score of 4 or less. The following outcome measures were examined: spatiotemporal and kinematic parameters. The Newcastle–Ottawa Scale was used to assess the quality of the studies.</p></div><div><h3>Findings</h3><p>Eleven studies including 270 patients with multiple sclerosis and 221 healthy controls. Three spatiotemporal parameters were modified both in patients with multiple sclerosis and healthy controls during dual-task performance: gait speed, stride length and the double support phase. No spatiotemporal parameter was affected during dual-task performance in patients with multiple sclerosis alone.</p></div><div><h3>Interpretation</h3><p>Dual-task performance could be useful for assessing gait impairments in patients with multiple sclerosis provided that assessments and protocols are standardized. Nevertheless, the spatiotemporal parameters did not allow discrimination between patients with multiple sclerosis at an early stage and healthy controls. Three-dimensional gait analysis during dual-task performance could be a useful approach for detecting early gait impairments in patients with multiple sclerosis, assessing their progression and adjusting rehabilitation programs.</p></div>","PeriodicalId":50992,"journal":{"name":"Clinical Biomechanics","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0268003324001323/pdfft?md5=895b1e1f06285b2cd86720f005d51112&pid=1-s2.0-S0268003324001323-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141604418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Age- and Parkinson-related differences in trunk and lower-limb muscle activation during four balance tasks: A case-control pilot study","authors":"Jérôme Bouchard-Tremblay ,&nbsp;Michael Théberge ,&nbsp;Tamami Ayoub ,&nbsp;Gabrielle Martel-Brosseau ,&nbsp;Marie-Pier Levasseur-Ouellet ,&nbsp;Maxim Tremblay ,&nbsp;Alexandra Houde-Thibeault ,&nbsp;Enafa Anais Wotto ,&nbsp;Fernando Rezende Carezolli ,&nbsp;Luc J. Hébert ,&nbsp;Rubens A. da Silva","doi":"10.1016/j.clinbiomech.2024.106298","DOIUrl":"10.1016/j.clinbiomech.2024.106298","url":null,"abstract":"<div><h3>Background</h3><p>Poor postural control has been reported in people with Parkinson's disease, which could be explained by the changes in muscular activation patterns related to antigravitational muscles. This study aims to measure the muscle activation of antigravitational muscles during balance tasks in individuals, with and without Parkinson's.</p></div><div><h3>Methods</h3><p>Sixteen (16) participants (9 with Parkinson's), aged ≥65 yrs., performed 2 × 30-s trials of 4 balance tasks (bipodal and semi-tandem opened eyes and closed eyes) on a force platform (center of pressure measurement); while surface electromyography measurements were obtained bilaterally on the multifidus at L5, biceps femoris and medialis gastrocnemius. Electromyography amplitude analysis was processed by the Root Mean Square (250 ms window epochs) and normalized by the peak of activation during the balance task, to determine each muscle's activity level.</p></div><div><h3>Findings</h3><p>The Parkinson's group reported lower muscle activation than control across tasks (in mean for multifidus = 8%, biceps femoris = 16%, gastrocnemius = 7%), although not statistically significant. Parkinson's reported significantly poorer postural control than control, mainly for the center of pressure sway ellipse area (<em>p</em> = 0.016) from challenge balance tasks such as semi-tandem.</p></div><div><h3>Interpretation</h3><p>Poor postural control was confirmed in the Parkinson's group, but not significantly associated by the changes from muscle activation of trunk and lower limbs, during balance performance.</p></div>","PeriodicalId":50992,"journal":{"name":"Clinical Biomechanics","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S026800332400130X/pdfft?md5=909f1b8e472df497399ff12564738d48&pid=1-s2.0-S026800332400130X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141472362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biomechanical testing of a computationally optimized far cortical locking plate versus traditional implants for distal femur fracture repair","authors":"Pawel Brzozowski ,&nbsp;Clayton Inculet ,&nbsp;Emil H. Schemitsch ,&nbsp;Radovan Zdero","doi":"10.1016/j.clinbiomech.2024.106296","DOIUrl":"10.1016/j.clinbiomech.2024.106296","url":null,"abstract":"<div><h3>Background</h3><p>This study experimentally validated a computationally optimized screw number and screw distribution far cortical locking distal femur fracture plate and compared the results to traditional implants.</p></div><div><h3>Methods</h3><p>24 artificial femurs were osteotomized with a 10 mm fracture gap 60 mm proximal to the intercondylar notch. Three fixation constructs were used. (i) Standard locking plates secured with three far cortical locking screws inserted according to a previously optimized distribution in the femur shaft (<em>n</em> = 8). (ii) Standard locking plates secured with four standard locking screws inserted in alternating plate holes in the femur shaft (n = 8). (iii) Retrograde intramedullary nail secured proximally with one anterior-posterior screw and distally with two oblique screws (n = 8). Axial hip forces (700 and 2800 N) were applied while measuring axial interfragmentary motion, shear interfragmentary motion, and overall stiffness.</p></div><div><h3>Findings</h3><p>Experimental far cortical locking plate results compared well to published computational findings. Far cortical locking femurs contained the highest axial motion within the potential ideal range of 0.2–1 mm and a sheer-to-axial motion ratio &lt; 1.6 at toe-touch weight-bearing (700 N). At full weight-bearing (2800 N), Standard locking-plated femurs had the only axial motion within 0.2–1 mm but had an excess shear-to-axial motion ratio. Nail-implanted femurs underperformed at both forces.</p></div><div><h3>Interpretation</h3><p>For toe-touch weight-bearing, the far cortical locking construct provided optimal biomechanics to allow moderate motion, which has been suggested to encourage early callus formation. Conversely, at full weight-bearing, the standard locking construct offered the biomechanical advantage on fracture motion.</p></div>","PeriodicalId":50992,"journal":{"name":"Clinical Biomechanics","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141472363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of three-dimensional femur and tibia postures on the parameters of standing long-leg radiographs for osteoarthritic knees in elderly female subjects","authors":"Kazutaka Otani ,&nbsp;Takashi Sato ,&nbsp;Koichi Kobayashi ,&nbsp;Tomoharu Mochizuki ,&nbsp;Osamu Tanifuji ,&nbsp;Ryota Katsumi ,&nbsp;Hiroyuki Kawashima","doi":"10.1016/j.clinbiomech.2024.106297","DOIUrl":"https://doi.org/10.1016/j.clinbiomech.2024.106297","url":null,"abstract":"<div><h3>Background</h3><p>Long-leg frontal radiographs of the lower extremities are used to assess knee osteoarthritis. Given the three-dimensional (3D) nature of alignment changes in osteoarthritis, postural alterations in the femur and tibia extend beyond the coronal plane (in-plane) to include the transverse and sagittal planes (out-of-plane). This study investigates the impact of these out-of-plane factors on in-plane knee alignment parameters observed in frontal radiographs.</p></div><div><h3>Methods</h3><p>A total of 97 osteoarthritic knees in women were examined. Using a 3D-to-two-dimensional (2D) image matching technique, we evaluated the 3D postures of the femur and tibia in the standing position as viewed from frontal radiographs in the world coordinate system. Statistical analyses were conducted to explore associations between these 3D postures and 2D alignment parameters obtained from frontal radiographs under identical conditions.</p></div><div><h3>Findings</h3><p>The femur exhibited a medial inclination of 2.7°, a posterior inclination of 3.9°, and an internal rotation of 4.2°, whereas the tibia showed a lateral inclination of 6.4°, an anterior inclination of 6.7°, and an internal rotation of 6.7°. Both coronal and rotational postures of femur and tibia influenced the hip-knee-ankle angle, mechanical axis percentage, and medial proximal tibial angle. However, only coronal factors of tibia impacted tibial joint line obliquity relative to the floor.</p></div><div><h3>Interpretation</h3><p>Attention should be paid to the potential impact of the out-of-plane postures of the femur and tibia on parameters assessed in plain frontal radiographs of the lower extremities.</p></div>","PeriodicalId":50992,"journal":{"name":"Clinical Biomechanics","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0268003324001293/pdfft?md5=38865dd6424cec2d7364ec702fdabc13&pid=1-s2.0-S0268003324001293-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141486393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prolonged quadriceps latency during gait early after anterior cruciate ligament injury predicts radiographic knee osteoarthritis 6-years after anterior cruciate ligament reconstruction","authors":"Naoaki Ito ,&nbsp;Jacob J. Capin ,&nbsp;Elanna K. Arhos ,&nbsp;Elizabeth Wellsandt ,&nbsp;Ryan T. Pohlig ,&nbsp;Thomas S. Buchanan ,&nbsp;Lynn Snyder-Mackler","doi":"10.1016/j.clinbiomech.2024.106301","DOIUrl":"10.1016/j.clinbiomech.2024.106301","url":null,"abstract":"<div><h3>Background</h3><p>The purpose was to explore quadriceps electromechanical function (quadriceps latency) during gait after anterior cruciate ligament injury as a predictor for radiographic knee osteoarthritis 6-years after anterior cruciate ligament reconstruction. Change in latency after preoperative physical therapy was also examined.</p></div><div><h3>Methods</h3><p>Quadriceps latency (time between peak knee moment and quadriceps electromyography) was calculated <em>before preoperative physical therapy</em> (2.4 [0.5–7.5] months after anterior cruciate ligament injury) and <em>after preoperative physical therapy</em> in 24 athletes. Participants were dichotomized into osteoarthritis (Kellgren and Lawrence grade ≥ 2) and non-osteoarthritis groups at 6-years. Forward selection logistic regression was performed using z-score normalized quadriceps latency and demographics. A 2 × 2 repeated measure ANOVA was performed for quadriceps latency between groups before and after preoperative physical therapy.</p></div><div><h3>Findings</h3><p>Quadriceps latency <em>before preoperative physical therapy</em> was the only predictor of 6-year radiographic osteoarthritis (<em>p</em> = 0.014, odds ratio [95% confidence interval] = 5.859 [1.435–23.924]). Time by group interaction was observed for quadriceps latency (<em>p</em> = 0.039, η²<em>p</em> = 0.179). In the osteoarthritis group, latency may reduce after training (<em>before preoperative physical therapy</em> = 115.7 ± 20.6 ms, <em>after preoperative physical therapy</em> = 99.5 ± 24.0 ms, <em>p</em> = 0.082).</p></div><div><h3>Interpretation</h3><p>Prolonged latency after anterior cruciate ligament injury may predict post-traumatic knee osteoarthritis 6-years after anterior cruciate ligament reconstruction. Latency may shorten with preoperative physical therapy, yet athletes still moved on to develop osteoarthritis. Quadriceps function may need intervention immediately following anterior cruciate ligament injury for prevention of post-traumatic knee osteoarthritis.</p></div>","PeriodicalId":50992,"journal":{"name":"Clinical Biomechanics","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141472364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Kinematic upper limb analysis outperforms electromyography at grading the severity of dystonia in children with cerebral palsy","authors":"Melissa Gar Yee Louey ,&nbsp;Adrienne Harvey ,&nbsp;Elyse Passmore ,&nbsp;David Grayden ,&nbsp;Morgan Sangeux","doi":"10.1016/j.clinbiomech.2024.106295","DOIUrl":"https://doi.org/10.1016/j.clinbiomech.2024.106295","url":null,"abstract":"<div><h3>Background</h3><p>Severity of dyskinesia in children with cerebral palsy is often assessed using observation-based clinical tools. Instrumented methods to objectively measure dyskinesia have been proposed to improve assessment accuracy and reliability. Here, we investigated the technique and movement features that were most suitable to objectively measure the severity of dystonia in children with cerebral palsy.</p></div><div><h3>Methods</h3><p>A prospective observational study was conducted with 12 participants with cerebral palsy with a predominant motor type of dyskinesia, spasticity, or mixed dyskinesia/spasticity who had upper limb involvement (mean age: 12.6 years, range: 6.7–18.2 years). Kinematic and electromyography data were collected bilaterally during three upper limb tasks. Spearman rank correlations of kinematic or electromyography features were calculated against dystonia severity, quantified by the Dyskinesia Impairment Scale.</p></div><div><h3>Findings</h3><p>Kinematic features were more influential compared to electromyography features at grading the severity of dystonia in children with cerebral palsy. Kinematic measures quantifying jerkiness of volitional movement during an upper limb task with a reaching component performed best (|r_s| = 0.78–0.9, <em>p</em> &lt; 0.001).</p></div><div><h3>Interpretation</h3><p>This study provides guidance on the types of data, features of movement, and activity protocols that instrumented methods should focus on when objectively measuring the severity of dystonia in children with cerebral palsy.</p></div>","PeriodicalId":50992,"journal":{"name":"Clinical Biomechanics","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141486395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of stroboscopic visual disruption on static stability measures in anterior cruciate ligament reconstructed individuals","authors":"Nathan J. Robey ,&nbsp;Otto Buchholz ,&nbsp;Shane P. Murphy ,&nbsp;Gary D. Heise","doi":"10.1016/j.clinbiomech.2024.106299","DOIUrl":"10.1016/j.clinbiomech.2024.106299","url":null,"abstract":"<div><h3>Background</h3><p>Those who undergo ACL reconstruction are at an increased risk of suffering a second ACL injury. A suggested rationale for the increased injury risk is sensory reweighting to the visual system to compensate for a lack of somatosensory information from the knee. Understanding this proposed visual reliance may help clinicians improve return to sport outcomes and reduce the risk of a subsequent ACL injury.</p></div><div><h3>Methods</h3><p>Thirteen ACL reconstructed individuals and thirteen matched controls completed two common static postural control assessments under three different visual conditions; eyes open, low visual disruption, and high visual disruption. Center of pressure data was collected for 30 s using force plates. Static postural stability was evaluated using the following: 1) root mean square distance, 2) mean velocity, 3) sway area, and 4) mean frequency.</p></div><div><h3>Findings</h3><p>No significant interactions between group and vision were observed. Significant differences between groups were observed for mean frequency in the double-limb stance (<em>p</em> &lt; .05). Additionally, significant differences were observed for visual conditions in both double-limb (mean velocity; p &lt; .05) and single-limb stances (root mean square distance, mean velocity, sway area, and mean frequency; p &lt; .05).</p></div><div><h3>Interpretation</h3><p>The findings of the current study suggest that ACL reconstructed individuals, who are at least two years removed from surgery, do not rely on visual information to a greater extent than controls during static postural stability assessments. Stroboscopic glasses may be a cost-effective alternative for rehabilitation purposes compared to the traditional binary eyes open vs. eyes closed methods.</p></div>","PeriodicalId":50992,"journal":{"name":"Clinical Biomechanics","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141472365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Changes in functional characteristics of heel fat pad with age","authors":"Toshihiro Maemichi ,&nbsp;Masatomo Matsumoto ,&nbsp;Takumi Okunuki ,&nbsp;Tsukasa Kumai","doi":"10.1016/j.clinbiomech.2024.106294","DOIUrl":"https://doi.org/10.1016/j.clinbiomech.2024.106294","url":null,"abstract":"<div><h3>Background</h3><p>This study aimed to investigate age-related changes in the heel fat pad's microchamber and macrochamber layers, particularly focusing on load-induced alterations. Understanding these changes is crucial for elucidating age-related differences in foot mechanics and their potential implications for mobility and comfort.</p></div><div><h3>Methods</h3><p>Fifty-five healthy individuals were divided into three age groups: young adults (≤29 years), middle-aged adults (30–44 years), and elderly individuals (≥45 years). Ultrasonic imaging was utilized to measure the thickness of the heel fat pad's microchamber and macrochamber layers under varying load conditions. Thickness, percentage changes, and ratios of load-induced thickness changes were calculated to assess age-related differences.</p></div><div><h3>Findings</h3><p>Under no-load conditions, both microchamber and macrochamber layers of the heel fat pad were significantly thicker in middle-aged and elderly individuals than in young adults. When load was applied middle-aged and elderly participants exhibited smaller changes in the macrochamber layer and larger changes in the microchamber layer compared to young adults.</p></div><div><h3>Interpretation</h3><p>Our findings suggest that age influences the structural characteristics and response of the heel fat pad to mechanical loading. Thicker heel fat pad layers in middle-aged and elderly individuals under no-load conditions may reflect age-related changes in fat distribution or composition. Moreover, differences in load-induced thickness changes indicate altered mechanical properties with age, potentially affecting shock absorption and overall foot function. Understanding these age-related variations can help develop interventions aimed at preserving foot health and mobility across the lifespan.</p></div>","PeriodicalId":50992,"journal":{"name":"Clinical Biomechanics","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0268003324001268/pdfft?md5=2777ca5d99bea0f316bcf75c61dab80f&pid=1-s2.0-S0268003324001268-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141596651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of foot orientation modifications on knee joint biomechanics during daily activities in people with and without knee osteoarthritis","authors":"Yi Wan ,&nbsp;Polly McGuigan ,&nbsp;James Bilzon ,&nbsp;Logan Wade","doi":"10.1016/j.clinbiomech.2024.106287","DOIUrl":"https://doi.org/10.1016/j.clinbiomech.2024.106287","url":null,"abstract":"<div><h3>Background</h3><p>Altered gait could influence knee joint moment magnitudes and cumulative damage over time. Gait modifications have been shown to reduce knee loading in people with knee osteoarthritis during walking, although this has not been explored in multiple daily activities. Therefore, this study investigated the effect of different foot orientations on knee loading during multiple daily activities in people with and without knee osteoarthritis.</p></div><div><h3>Methods</h3><p>Thirty people with knee osteoarthritis and twenty-nine without (control) performed walking, stair ambulation and sit-to-stand across a range of foot progression angles (neutral, toe-in, toe-out and preferred). Peak knee adduction moment, knee adduction moment impulse and knee pain were compared across a continuous range of foot orientations, between activities, and groups.</p></div><div><h3>Findings</h3><p>Increased foot progression angle (more toe-in) reduced 1st peak knee adduction moment across all activities in both knee osteoarthritis and control (<em>P</em> &lt; 0.001). There was a greater reduction in knee adduction moment in the control group during walking and stair ambulation (<em>P</em> ≤ 0.006), where the knee osteoarthritis group already walked preferably less toe-out than the control group. Under preferred condition, stair descent had the greatest knee loading and knee pain compared to other activities.</p></div><div><h3>Interpretation</h3><p>Although increased foot progression angle (toward toe-in) appeared to be more effective in reducing knee loading for all activities, toe-in modification might not benefit stair ambulation. Future gait modification should likely be personalised to each patient considering the individual difference in preferred gait and knee alignment required to shift the loading medially or laterally.</p></div>","PeriodicalId":50992,"journal":{"name":"Clinical Biomechanics","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0268003324001190/pdfft?md5=2d933d8dcfdb7a80f3474ec7a64b9e6c&pid=1-s2.0-S0268003324001190-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141314185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gait classification of knee osteoarthritis patients using shoe-embedded internal measurement units sensor","authors":"Ahmed Raza ,&nbsp;Yusuke Sekiguchi ,&nbsp;Haruki Yaguchi ,&nbsp;Keita Honda ,&nbsp;Kenichiro Fukushi ,&nbsp;Chenhui Huang ,&nbsp;Kazuki Ihara ,&nbsp;Yoshitaka Nozaki ,&nbsp;Kentaro Nakahara ,&nbsp;Shin-Ichi Izumi ,&nbsp;Satoru Ebihara","doi":"10.1016/j.clinbiomech.2024.106285","DOIUrl":"10.1016/j.clinbiomech.2024.106285","url":null,"abstract":"<div><h3>Background</h3><p>Knee osteoarthritis negatively affects the gait of patients, especially that of elderly people. However, the assessment of wearable sensors in knee osteoarthritis patients has been under-researched. During clinical assessments, patients may change their gait patterns under the placebo effect, whereas wearable sensors can be used in any environment.</p></div><div><h3>Methods</h3><p>Sixty patients with knee osteoarthritis and 20 control subjects were included in the study. Wearing shoes with an IMU sensor embedded in the insoles, the participants were required to walk along a walkway. The sensor data were collected during the gait. To discriminate between healthy and knee osteoarthritis patients and to classify different subgroups of knee osteoarthritis patients (patients scheduled for surgery vs. patients not scheduled for surgery; bilateral knee osteoarthritis diagnosis vs. unilateral knee osteoarthritis diagnosis), we used a machine learning approach called the support vector machine. A total of 88 features were extracted and used for classification.</p></div><div><h3>Findings</h3><p>The patients vs. healthy participants were classified with 71% accuracy, 85% sensitivity, and 56% specificity. The “patients scheduled for surgery” vs. “patients not scheduled for surgery” were classified with 83% accuracy, 83% sensitivity, and 81% specificity. The bilateral knee osteoarthritis diagnosis vs. unilateral knee osteoarthritis diagnosis was classified with 81% accuracy, 75% sensitivity, and 79% specificity.</p></div><div><h3>Interpretation</h3><p>Gait analysis using wearable sensors and machine learning can discriminate between healthy and knee osteoarthritis patients and classify different subgroups with reasonable accuracy, sensitivity, and specificity. The proposed approach requires no complex gait factors and is not limited to controlled laboratory settings.</p></div>","PeriodicalId":50992,"journal":{"name":"Clinical Biomechanics","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141391993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}