Clinical Biomechanics最新文献

{"title":"Understanding load distribution in high tibial osteotomies: An inverse Discrete Element Analysis approach","authors":"A. Van Oevelen ,&nbsp;K. Duquesne ,&nbsp;M. Huys ,&nbsp;A. Burssens ,&nbsp;A. Chevalier ,&nbsp;G. Steenackers ,&nbsp;E. Audenaert","doi":"10.1016/j.clinbiomech.2026.106748","DOIUrl":"10.1016/j.clinbiomech.2026.106748","url":null,"abstract":"<div><h3>Background</h3><div>With up to 40% of knee osteotomies yielding suboptimal results, improved preoperative planning is needed. This study aimed to develop an inverse Discrete Element Analysis (iDEA) approach to calculate and compare patient-specific pressure patterns against traditional clinical metrics, pre- and postoperatively.</div></div><div><h3>Methods</h3><div>Eight varus knee osteotomy patients and eight matched controls were analyzed. Personalized knee geometries were generated from Weight-Bearing Computed Tomography (WBCT) scans using Statistical Shape Modeling. Automated angular measurements were conducted and Joint Space Widths (JSW) were calculated as the Euclidean distance between the femoral and tibial bones. The iDEA approach calculated preoperative, postoperative and control pressure patterns. Group comparisons utilized one-way ANOVA or Kruskal-Wallis testing, depending on normality. A Spearman rank test was performed to assess the correlation between changes in joint space width and mean stress distribution.</div></div><div><h3>Findings</h3><div>The preoperative group showed significant differences compared to the controls across all angular measurements (Hip-Knee-Ankle angle (HKA): <em>p</em> &lt; 0.001, Joint Line Conversion Angle: p &lt; 0.001, lateral Proximal Tibial Angle: <em>p</em> = 0.044) and the medial-to-lateral JSW ratio (<em>p</em> = 0.017). Postoperatively, only the HKA remained significantly different from controls (p = 0.044). Pressure calculations revealed significantly higher peak stress ratios preoperatively than in controls (<em>p</em> = 0.029). Two subjects showed postoperative worsening of JSW and pressure patterns while angular measurements improved. JSW increases were correlated with decreases in mean stress (correlation coefficient = −0.54,<em>p</em> = 0.033).</div></div><div><h3>Interpretation</h3><div>The iDEA approach quantified intra-articular pressure distributions and revealed a general normalization trend postoperatively, supporting the effectiveness of knee osteotomy. The identification of postoperative deteriorations not captured by traditional metrics, underscores the added value of the iDEA framework.</div></div>","PeriodicalId":50992,"journal":{"name":"Clinical Biomechanics","volume":"133 ","pages":"Article 106748"},"PeriodicalIF":1.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145986735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Distance-related changes in gait parameters during uneven-surface walking in people with stroke versus healthy controls: A cross-sectional analysis","authors":"Yasuhiro Inui ,&nbsp;Naomichi Mizuta ,&nbsp;Yuta Terasawa ,&nbsp;Tomoya Tanaka ,&nbsp;Naruhito Hasui ,&nbsp;Kazuki Hayashida ,&nbsp;Yuki Nishi ,&nbsp;Shu Morioka","doi":"10.1016/j.clinbiomech.2026.106747","DOIUrl":"10.1016/j.clinbiomech.2026.106747","url":null,"abstract":"<div><h3>Background</h3><div>People with Stroke (PwS) struggle with walking outdoors, especially on uneven surfaces, which limits their social participation. Distance-related changes on uneven surfaces remain unclear. We compared these changes between PwS and healthy controls (HC).</div></div><div><h3>Methods</h3><div>Nineteen PwS and 19 HC walked four laps on a 10-m uneven surface. Gait speed, root mean square of trunk acceleration (stability), maximum joint angles, electromyography (EMG) amplitude, and instantaneous mean frequency (IMNF) were measured. Linear mixed models were used to compare gait-parameter changes across laps.</div></div><div><h3>Findings</h3><div>No group × lap interaction was detected for gait speed, stability, stance-phase hip extension, or swing-phase knee flexion. An interaction was observed for ankle dorsiflexion during initial contact (<em>p</em> = 0.036; decreased across laps in PwS). For EMG amplitude, tibialis anterior during initial contact showed an interaction (<em>p</em> = 0.036; increased only in HC). Regarding IMNF, gluteus medius showed a group main effect during mid-stance (<em>p</em> &lt; 0.001; higher in PwS) and an interaction during terminal stance (p = 0.036; decreased only in PwS); during mid-swing, group main effects were observed for rectus femoris (<em>p</em> = 0.044), biceps femoris (<em>p</em> = 0.011), and gluteus medius (<em>p</em> = 0.023), with higher IMNF in PwS.</div></div><div><h3>Interpretation</h3><div>PwS maintained gait speed and stability, increasing distances on uneven surfaces, showing adaptations comparable to HC. PwS did not sufficiently augment tibialis anterior amplitude, accompanied by reduced ankle dorsiflexion and limited shock absorption. Elevated IMNF indicates greater motor-unit recruitment contributing to the maintenance of joint angles, whereas gluteus medius IMNF declined during terminal stance, suggesting fatigue. Overall, adaptation was present but limited, with a risk of fatigue.</div></div>","PeriodicalId":50992,"journal":{"name":"Clinical Biomechanics","volume":"133 ","pages":"Article 106747"},"PeriodicalIF":1.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146013209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Standing anterior pelvic tilt is correlated with the proximal femur shape of individuals with cam morphology","authors":"Seth J. Kussow ,&nbsp;Rich J. Lisonbee ,&nbsp;Bergen Braun ,&nbsp;Jared L. Zitnay ,&nbsp;Megan K. Mills ,&nbsp;Stephen K. Aoki ,&nbsp;Travis G. Maak ,&nbsp;Penny R. Atkins ,&nbsp;Andrew E. Anderson","doi":"10.1016/j.clinbiomech.2026.106767","DOIUrl":"10.1016/j.clinbiomech.2026.106767","url":null,"abstract":"<div><h3>Background</h3><div>Spinopelvic morphology and alignment have been theorized to play a role in causing femoroacetabular impingement syndrome symptoms in individuals with cam morphology. However, prior studies have used hip morphological and alignment measurements that are interdependent, limiting understanding of form-function relationships.</div></div><div><h3>Methods</h3><div>Statistical shape modeling and biplane videoradiography were used for accurate, 3D assessment of femur and pelvis morphology and in vivo standing hip and pelvis orientation among individuals with and without cam morphology and impingement symptoms. Group differences in standing posture and shape were assessed, along with correlations between shape and posture.</div></div><div><h3>Findings</h3><div>Patients stood with less anterior pelvic tilt and greater hip extension than asymptomatic individuals without cam morphology. A more patient-like proximal femur shape was correlated with less anterior pelvic tilt. Asymptomatic individuals with cam morphology showed no standing posture differences but had a unique pelvic shape featuring an internally rotated ilium. Further, femur and pelvis anatomical features, primarily describing changes at hip-crossing muscle attachment sites and the sacroiliac region, showed significant associations with hip and pelvis orientation in the sagittal and frontal planes.</div></div><div><h3>Interpretation</h3><div>Patients with symptomatic impingement due to cam morphology may preemptively adopt less anterior pelvic tilt to enable functional hip range of motion. The associations between shape and standing posture may identify patients best suited for treatment involving pelvic posture modification. Results support further investigation of hip crossing muscle characteristics and spinopelvic alignment during dynamic activities to strengthen understanding of the underlying mechanisms responsible for symptoms in patients with femoroacetabular impingement syndrome.</div></div>","PeriodicalId":50992,"journal":{"name":"Clinical Biomechanics","volume":"133 ","pages":"Article 106767"},"PeriodicalIF":1.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146047357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A novel method for screening diabetic peripheral neuropathy using fused surface electromyogram signal and mechanomyography signal","authors":"Yanbin Guo ,&nbsp;Mingyue Wang ,&nbsp;Guoping Wang ,&nbsp;Wenxuan Sun ,&nbsp;Xiao-Jian Han ,&nbsp;Lingjuan Li ,&nbsp;Xin-Hui Qu ,&nbsp;Zibo Feng","doi":"10.1016/j.clinbiomech.2025.106737","DOIUrl":"10.1016/j.clinbiomech.2025.106737","url":null,"abstract":"<div><h3>Background</h3><div>Diabetes peripheral neuropathy (DPN), one of the most common complications in people with diabetes, can seriously undermine their quality of life. Early detection and treatment of DPN is of great significance to the diabetes population. Nerve conduction studies, the gold standard for diagnosing DPN, causes substantial discomfort for people and requires specialized personnel and expensive equipment, making it challenging to implement as a mass screening tool for DPN.</div></div><div><h3>Methods</h3><div>Here, a novel, non-invasive and convenient screening method for DPN is proposed. In the proposed method, surface electromyography and mechanomyography data are acquired in a non-invasive and painless manner from people’ dorsalis pedis muscles. The acquired data are then processed by means of downsampling, motion data extraction, and subsequently converted into images, which are utilized for diagnosing DPN or non-DPN by a convolutional neural network.</div></div><div><h3>Findings</h3><div>The proposed method is developed based on actual data from 167 people with diabetes. After 4-fold cross validation of the method, the mean accuracy, sensitivity and specificity are evaluated to be 96.15 %, 91.39 % and 98.78 % with variances of 0.003 %, 0.017 % and 0.00014 %, respectively. Furthermore, the method is preliminary tested on 21 people with diabetes, resulting in accuracy, sensitivity and specificity of 95.48 %, 90.91 % and 98.88 %, respectively. Notably, the screening process for a single diabetic using this method can be completed in under 10 min. The results above demonstrate the efficacy of the method in diagnosing DPN.</div></div><div><h3>Interpretation</h3><div>The proposed method has the considerable potential for noninvasive and convenient screening of DPN without requiring professionals or expensive equipment.</div></div>","PeriodicalId":50992,"journal":{"name":"Clinical Biomechanics","volume":"132 ","pages":"Article 106737"},"PeriodicalIF":1.4,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145776296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Load distribution between the radius and ulna through the forearm interosseous membrane: Effects of elbow flexion and Varus–Valgus alignment","authors":"Takahiro Yamazaki,&nbsp;Yusuke Matsuura,&nbsp;Takashi Nomoto,&nbsp;Seiji Ohtori,&nbsp;Takane Suzuki","doi":"10.1016/j.clinbiomech.2025.106742","DOIUrl":"10.1016/j.clinbiomech.2025.106742","url":null,"abstract":"<div><h3>Background</h3><div>The forearm interosseous membrane helps distribute load between the radius and ulna, yet the combined influence of elbow flexion and varus–valgus alignment on load transfer remains unclear. This study aimed to quantify interosseous membrane-mediated load transfer across elbow flexion angles under varus and valgus loading.</div></div><div><h3>Methods</h3><div>Seven fresh-frozen cadaveric forearms were tested using a custom setup with tension/compression force sensors mounted to record loads transmitted through the radius and ulna. Specimens were positioned at multiple elbow flexion angles within 0–90° under controlled varus and valgus loading. The interosseous membrane load-transfer rate was calculated from synchronized force data, and conditions were compared statistically (Wilcoxon signed-rank test).</div></div><div><h3>Findings</h3><div>The interosseous membrane load-transfer rate was significantly greater under varus than valgus loading (mean ± SD: 24.4 ± 14.8 % vs 10.1 ± 7.9 %, <em>p</em> &lt; 0.001). Across the tested elbow flexion angles, flexion had no significant effect on the load-transfer rate in either alignment condition.</div></div><div><h3>Interpretation</h3><div>Within the tested range, varus–valgus alignment, rather than elbow flexion angle, primarily determines the magnitude of interosseous membrane -mediated load transfer. These findings provide biomechanical insight relevant to understanding injury mechanisms and may inform alignment considerations during rehabilitation or immobilization.</div></div>","PeriodicalId":50992,"journal":{"name":"Clinical Biomechanics","volume":"132 ","pages":"Article 106742"},"PeriodicalIF":1.4,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145791000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Postural control in individuals with mental disorders: A systematic review and META-analysis","authors":"Carla Emilia Rossato ,&nbsp;Aline Josiane Waclawovsky ,&nbsp;Gabriela dos Santos de Souza ,&nbsp;Debora Tornquist ,&nbsp;Carlos Bolli Mota ,&nbsp;Aron Ferreira da Silveira ,&nbsp;Felipe Barreto Schuch","doi":"10.1016/j.clinbiomech.2025.106741","DOIUrl":"10.1016/j.clinbiomech.2025.106741","url":null,"abstract":"<div><div>Background: Some evidence suggests that people with mental disorders presents postural balances, but there is a scarcity of meta-analyses summarizing the evidence comparing posture of people with mental disorders with paired controls. Objectives: The aim of this study was to summarize the evidence comparing postural balance between individuals with mental disorders and healthy controls. Methods: We searched databases (PubMed, PsycINFO, Embase, SportDiscus and Web of Science) from inception until June 3, 2025, for studies comparing postural balance, assessed by center of pressure (COP), in people with and without mental disorders. The primary outcome was the COP in different axes (X and Y), assessed under multiple conditions (eyes open/close, feet apart/together). Random effects meta-analyses calculated the mean differences (MD) between groups Whenever relevant; heterogeneity was explored by meta-regression and subgroup analyses. The risk of bias of the included studies was assessed using the Newcastle-Ottawa scale (NOS). The protocol was registered with PROSPERO (CRD42024554769). Findings: 33 studies were included, totaling 2.601 participants (1.424 with mental disorders [mean age = 39.30 ± 10.54 years, 43.05 % women] and 1.177 controls [mean age = 39.68 ± 10.35, 50.44 % women]. People with mental disorders showed greater COP area sway in the feet apart and eyes open (<em>N</em> = 12, MD = 0.20, 95 %CI 0.07, 0.32, I² = 62.67) and eyes closed conditions (<em>N</em> = 8, MD = 0.42, 95 %CI 0.15, 0.69, I² = 59.10) compared to controls. The majority of studies (96.96 %) had a low or moderate risk of bias. Interpretation: Individuals with mental disorders show alterations in postural balance compared to healthy controls.</div></div>","PeriodicalId":50992,"journal":{"name":"Clinical Biomechanics","volume":"132 ","pages":"Article 106741"},"PeriodicalIF":1.4,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145840906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anterior talofibular ligament laxity restricts deep deltoid ligament strain in a cadaveric model of acquired planus 'The deep deltoid paradoxical intact sign'","authors":"Zhikai Li ,&nbsp;Gavin E. Jarvis ,&nbsp;Tobia Nava ,&nbsp;Zhiheng Li ,&nbsp;Luke Maxwell ,&nbsp;Cecilia Brassett ,&nbsp;Stephanie Potten ,&nbsp;Alan R. Norrish ,&nbsp;Chandra S. Pasapula","doi":"10.1016/j.clinbiomech.2025.106734","DOIUrl":"10.1016/j.clinbiomech.2025.106734","url":null,"abstract":"<div><h3>Background</h3><div>The Deep Deltoid Ligament (DDL) laxity development and subsequent rupture can occur in pes planus. Anteromedial drawer tests reveal reduced anteromedial anteroposterior (AP) ankle laxity with concurrent anterior talofibular ligament (ATFL) laxity. The paradoxical protection conferred by ATFL laxity to the DDL in progressive collapsing foot deformity (PCFD) warrants further investigation.</div></div><div><h3>Aims</h3><div>Investigate the effect of ATFL laxity on DDL laxity development in an experimental flat-foot model.</div></div><div><h3>Methods</h3><div>18 cadaveric feet were assigned to three experimental protocols: (1) control, (2) induced flat-foot, and (3) induced flat-foot with ATFL sectioned. The flat-foot model was induced by sectioning the plantar fascia, spring ligament (SL), and the plantar first tarsometatarsal ligament. Sectioning the SL due to the interconnectedness would result in defunctioning of the superficial deltoid. Positional markers were placed on the medial malleolus, fibula, and talus. Jig-mounted feet underwent 2000 loading cycles. Every 200 cycles, images were taken before and after antero-posterior force application and the markers used to determine anteromedial and anterolateral AP separation, modelled as a linear function of cycle number.</div></div><div><h3>Findings</h3><div>In ATFL-intact flat feet, antero-posterior force-induced anteromedial separation and thus DDL laxity increased by 3.45 ± 0.34 mm per 1000 cycles (mean ± SD), whereas in ATFL-sectioned and control feet, this was 0.64 ± 0.59 and 0.59 ± 0.32 mm per 1000 cycles respectively. Minimal cycle-induced change occurred in anterolateral separation in the three conditions. ATFL-sectioned feet had greater antero-posterior force-induced anterolateral separation (9.33 ± 1.42 mm) before cyclic loading than control (1.85 ± 0.85 mm) and ATFL-intact flat feet (1.85 ± 0.31 mm).</div></div><div><h3>Interpretation</h3><div>Sectioning ATFL in experimentally induced flat feet paradoxically reduces anteromedial separation/DDL laxity.</div></div>","PeriodicalId":50992,"journal":{"name":"Clinical Biomechanics","volume":"132 ","pages":"Article 106734"},"PeriodicalIF":1.4,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145926240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gait analysis and prediction in Parkinson's disease using rhythmic auditory stimulation: A data-driven approach with machine learning models","authors":"Jingyuan Lin","doi":"10.1016/j.clinbiomech.2025.106725","DOIUrl":"10.1016/j.clinbiomech.2025.106725","url":null,"abstract":"<div><h3>Background</h3><div>Gait disturbance is a core feature of Parkinson's disease (PD), contributing to mobility loss and fall risk. Rhythmic auditory stimulation (RAS) can improve gait, yet response varies across patients. This study evaluated RAS effects on gait and developed a model to predict responders.</div></div><div><h3>Methods</h3><div>Three hundred PD patients were enrolled and assigned to RAS or control groups. Gait data were collected with a 3D motion capture system and force plates, and baseline assessments included UPDRS-III and MoCA score. Clinical and gait features (stride length, speed, swing time, double support) were analyzed. Paired analyses compared pre- and post-RAS changes. Machine learning models (Random Forest, XGBoost, SVM) were trained on demographic and baseline gait data to predict RAS responsiveness, defined as improvement in gait speed and double support time.</div></div><div><h3>Findings</h3><div>Among the 171 patients in the RAS group, 116 (67.8 %) were identified as responders based on improvements in gait speed and double support time.The RAS group showed significant improvements in gait speed (+0.14 m/s), stride length (+0.10 m), and reductions in double support (−0.026 s) and variability (−0.012), all <em>p</em> &lt; 0.001. Among models, Random Forest classifier demonstrated the best balanced performance (AUC = 0.713, accuracy = 0.71, F1 = 0.64, recall = 0.87), outperforming SVM and XGBoost models. Feature importance highlighted UPDRS-III, stride length, MoCA score, and gait asymmetry as key predictors.</div></div><div><h3>Interpretation</h3><div>RAS significantly enhances gait performance in PD, though with individual variability. A data-driven machine learning framework enables reasonable prediction of responders, supporting personalized gait rehabilitation strategies in clinical practice.</div></div>","PeriodicalId":50992,"journal":{"name":"Clinical Biomechanics","volume":"132 ","pages":"Article 106725"},"PeriodicalIF":1.4,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145665407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A partial differential equation model of a novel treatment for chronic wound biofilm infections","authors":"Sandeep Shirgill ,&nbsp;Najida Begum ,&nbsp;Sarah A. Kuehne ,&nbsp;Gowsihan Poologasundarampillai ,&nbsp;Sara Jabbari ,&nbsp;John Ward","doi":"10.1016/j.clinbiomech.2025.106744","DOIUrl":"10.1016/j.clinbiomech.2025.106744","url":null,"abstract":"<div><h3>Background:</h3><div>Chronic wounds, such as pressure ulcers, venous leg ulcers, and diabetic foot ulcers, present a significant healthcare challenge due to their prolonged healing times and association with biofilm infections. This study introduces a mathematical model to investigate wound healing dynamics during the proliferative stage, focusing on chronic wound conditions characterised by poor vascularisation, clotting deficiencies, cellular senescence, and bacterial biofilms.</div></div><div><h3>Methods:</h3><div>The model examines the interactions between fibroblasts, keratinocytes, granulation tissue, nutrients, and signalling molecules under normal and impaired healing scenarios. The potential of bioactive glass fibres, doped with antimicrobial and wound healing ions, is also explored.</div></div><div><h3>Findings:</h3><div>Model results reflect the impairment of wound healing by biofilm infections, with larger bacterial populations leading to poorer outcomes. Simulations suggest that antimicrobial ions reduce bacterial populations and improve nutrient availability, supporting fibroblast and immune cell activity. Reapplication of bioactive glass fibres enhances ion concentrations, further promoting granulation tissue formation and wound closure under certain conditions.</div></div><div><h3>Interpretation:</h3><div>Results identify critical parameters that hinder healing in untreated wounds and demonstrate how bioactive glass fibre design can be optimised to enhance healing outcomes. This work provides a foundation for designing cost-effective treatments for chronic wounds, addressing a significant unmet clinical need.</div></div>","PeriodicalId":50992,"journal":{"name":"Clinical Biomechanics","volume":"132 ","pages":"Article 106744"},"PeriodicalIF":1.4,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145977172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to “Strain in vertebral artery during passive cervical range of motion and spinal manipulation therapy: A systematic review and meta-analysis” [Clinical Biomechanics 130 (2025) 106685]","authors":"Caroline Fagundes ,&nbsp;Felipe Coutinho Kullmann Duarte ,&nbsp;Walter Herzog","doi":"10.1016/j.clinbiomech.2025.106721","DOIUrl":"10.1016/j.clinbiomech.2025.106721","url":null,"abstract":"","PeriodicalId":50992,"journal":{"name":"Clinical Biomechanics","volume":"132 ","pages":"Article 106721"},"PeriodicalIF":1.4,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145727086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}