Agnieszka Pochrzęst-Motyczyńska, Jarosław Pinkas, Urszula Religioni, Janusz Ostrowski
{"title":"Development of telemedicine in Poland - organizational, ethical and communication challenges.","authors":"Agnieszka Pochrzęst-Motyczyńska, Jarosław Pinkas, Urszula Religioni, Janusz Ostrowski","doi":"10.26444/aaem/192793","DOIUrl":"https://doi.org/10.26444/aaem/192793","url":null,"abstract":"<p><strong>Introduction and objective: </strong>We are witnessing a revolution in the field of telemedicine, which has begun to be used in every medical specialty. The aim of the review is to identify and summarise ethical and communication challenges related to the development of telemedicine in Poland.</p><p><strong>Review methods: </strong>Scientific articles found in the electronic databases PubMed and ScienceDirect were analyzed using key words: telemedicine; Distance Counseling; e-Health Service and Digital Health Technology. Guidelines of the World Health Organization (WHO), the American Telemedicine Association (ATA) and the General Medical Council (GMC) were taken into account. Data is presented on e-services of the Ministry of Health, the E-Health Centre and National Health Fund.</p><p><strong>Brief description of the state of knowledge: </strong>According to data from the National Health Fund, since 2020, the percentage of online consultation provided in Primary Health Care and Specialist Outpatient Care has been decreasing. In Poland, the potential resulting from the development of e-services is still untapped. The introduction of e-prescription and e-referral is convenient for the patient and staff, but does not have a health effect.</p><p><strong>Summary: </strong>In order to improve the efficiency of the health care system, it is necessary to focus on the further development of new e-services. It is worth introducing solutions that allow the use of medical data and test results to relieve the patient of the burden of transferring medical records to subsequent doctors. It is necessary to develop a standard for the provision of teleconsultations in order to eliminate pathological prescription issuance through online platforms providing consultations. Remote provision of medical services also requires further development of the digital competences of both staff and patients.</p>","PeriodicalId":50970,"journal":{"name":"Annals of Agricultural and Environmental Medicine","volume":"32 1","pages":"59-65"},"PeriodicalIF":1.3,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143755802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tomasz Wiśniowski, Jarosław Bryda, Justyna Domosud, Sławomir Jan Wątroba
{"title":"Extracellular matrix metalloproteinases in pathophysiology, diagnostics and treatment of renal cell carcinoma - current state of knowledge and future perspectives.","authors":"Tomasz Wiśniowski, Jarosław Bryda, Justyna Domosud, Sławomir Jan Wątroba","doi":"10.26444/aaem/192555","DOIUrl":"https://doi.org/10.26444/aaem/192555","url":null,"abstract":"<p><strong>Introduction and objective: </strong>Despite a significant improvement in the diagnosis and treatment of renal cell carcinoma over the past two decades, this cancer still remains one of the most lethal urological neoplasms.</p><p><strong>Review methods: </strong>Databases were searched using the keywords: 'RCC', 'MMP', 'TIMP', 'signaling pathway', and 'pathophysiological'. The titles of these entries were analyzed to assess complementarity, obtaining 721 entries. Relevance was then assessed by analyzing the abstracts, and 387 entries were selected. Based on criteria such as number of citations, research methods, sample size and representativeness, 248 references were finally selected. Finally, 181 items were included in the literature.</p><p><strong>Brief description of the state of knowledge: </strong>Extracellular matrix metalloproteinases plays an important role in the remodeling of the extracellular matrix. They participate in the initiation and regulation of inflammatory and carcinogenic processes.</p><p><strong>Summary: </strong>The analysis of available literature shows that, from a biochemical point of view, the most important influence on the development of renal cell carcinoma and the formation of metastases is the imbalance between the activity of metalloproteinases and the concentration of their tissue inhibitors. Hope for the future lies in monoclonal antibodies used to selectively block individual metalloproteinases, which may be of particula importance in highly vascularized tumours, which undoubtedly include renal cell carcinoma. Additionally, assessment of metalloproteinases activity could assist in selecting patients for surgical treatment or active surveillance.</p>","PeriodicalId":50970,"journal":{"name":"Annals of Agricultural and Environmental Medicine","volume":"32 1","pages":"27-45"},"PeriodicalIF":1.3,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143755805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Piotr Adamczuk, Konrad Jamka, Hubert Bojar, Joanna Szala-Rycaj, Aleksandra Szewczyk, Krzysztof Bogumił Sawicki, Grzegorz Raszewski
{"title":"The effect of the antioxidant N-acetylcysteine on cholinesterase activity in the brain and blood during Pirimiphos methyl poisoning in the course of treatment with atropine alone, and with atropine and obidoxime.","authors":"Piotr Adamczuk, Konrad Jamka, Hubert Bojar, Joanna Szala-Rycaj, Aleksandra Szewczyk, Krzysztof Bogumił Sawicki, Grzegorz Raszewski","doi":"10.26444/aaem/199716","DOIUrl":"https://doi.org/10.26444/aaem/199716","url":null,"abstract":"<p><strong>Introduction and objective: </strong>The antioxidant N-acetylcysteine (NAC) may help in the treatment of organophosphates poisoning, including Pirymiphos methyl (PM). However, there is no information on the effect of NAC on target cholinesterases during the core treatment with atropine and obidoxime after acute and chronic exposure to PM. The impact was investigated of NAC on the functional status of target cholinesterases in the brain and blood during treatment with atropine (ATR) and/or obidoxime (OBID) in PM-induced toxicity.</p><p><strong>Material and methods: </strong>All experiments were performed on Male Swiss mice. The animals were intoxicated with PM and treated with OBID and/or ATR with or without and NAC, in various combinations (with 2-3 drugs) used simultaneously after intoxication. Total acetylcholinesterase activity (AChE) in brain and blood and plasma butyrylcholinesterase activity (BChE) were monitored at 2 and 72 h after intoxication. Enzyme activity was determined using Ellman's colorimetric method.</p><p><strong>Results: </strong>The applied therapies with OBID, ATR and NAC in various configurations significantly reactivated PM-inhibited AChE in the brain and erythrocytes and the BChE in the plasma. The benefits of NAC administration in combination with ATR and/or OBID therapy have also been reported to restore AChE activity in the brain. NAC may reduce the dose of ATR in the treatment of PM poisoning.</p><p><strong>Conclusions: </strong>Adjunctive treatment offered by NAC can reduce or prevent the deleterious effects against PM-induced toxicity. Therefore, NAC remains a strong candidate for adjunct treatment for OP-poisoning, including PM, although additional preclinical and clinical studies are needed.</p>","PeriodicalId":50970,"journal":{"name":"Annals of Agricultural and Environmental Medicine","volume":"32 1","pages":"116-121"},"PeriodicalIF":1.3,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143754921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Diagnostic values of trimethylamine (TMA) and trimethylamine N-oxide (TMAO) in the prediction of gestational diabetes mellitus - a systematic review and meta-analysis.","authors":"Monika Tomaszewska, Michal Pruc, Damian Swieczkowski, Stepan Feduniw, Zuzanna Gaca, Lukasz Jankowski, Magdalena Florek-Luszczki, Lukasz Szarpak, Halla Kaminska","doi":"10.26444/aaem/197072","DOIUrl":"https://doi.org/10.26444/aaem/197072","url":null,"abstract":"<p><strong>Introduction and objective: </strong>Gestational diabetes mellitus (GDM) is a growing concern for public health, affecting approximately 20% of pregnancies globally. This underscores an urgent need for improved diagnostic and management strategies. This study examines the relationship between trimethylamine N-oxide (TMAO) and its precursor trimethylamine (TMA) levels and GDM, aiming to deepen our understanding of GDM's pathophysiology and identify novel therapeutic targets.</p><p><strong>Material and methods: </strong>The meta-analysis adhered to the Preferred Reporting Items for Systematic Reviews and Meta-analysis (PRISMA) guidelines. The PubMed, Scopus, Web of Science, and the Cochrane Library electronic databases were comprehensively searched up to 11 July 2024.</p><p><strong>Results: </strong>The analysis included five studies, encompassing a total of 1,726 participants. The studies reported TMAO levels among GDM and non-GDM patients. The reported TMAO levels among GDM and non-GDM patients were 57.66 ± 42.2 and 47.94 ± 30.86, respectively (SMD = -0.49; 95%CI: -2.69 to 1.71; p = 0.66). However, TMA levels in the GDM group (224.28 ± 39.88) were statistically higher than in the non-GDM group (124.05 ± 21.93; SMD = 3.11; 95%CI: 2.84 to 3.37; p<0.001).</p><p><strong>Conclusions: </strong>The best available evidence indicates that while TMA levels are significantly increased in GDM, TMAO does not seem to have a diagnostic role in gestational diabetes mellitus. More prospective trials evaluating TMA and TMAO values among pregnant women with gestational diabetes mellitus are required.</p>","PeriodicalId":50970,"journal":{"name":"Annals of Agricultural and Environmental Medicine","volume":"32 1","pages":"111-115"},"PeriodicalIF":1.3,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143755803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Beata Fiecek, Tomasz Szewczyk, Grażyna Lewandowska, Tomasz Chmielewski
{"title":"<i>Borrelia miyamotoi</i> DNA in a patient suspected of Lyme borreliosis.","authors":"Beata Fiecek, Tomasz Szewczyk, Grażyna Lewandowska, Tomasz Chmielewski","doi":"10.26444/aaem/191046","DOIUrl":"https://doi.org/10.26444/aaem/191046","url":null,"abstract":"<p><p><b>Introduction and Objective</b>. Manifestations of infection caused by <i>Borrelia miyamotoi</i> can mimic highly variable symptoms of Lyme borreliosis. The aim of the study was to detect DNA from <i>B. miyamotoi</i> samples from patients with suspected neuroborreliosis. <b>Materials and Method</b>. Samples of blood serum and cerebrospinal fluid (CSF) were collected from 133 patients. Diagnosis was established by the detection of specific antibodies to <i>Borrelia burgdorferi</i> sensu lato (s.l.) with ELISA and immunoblot. All Borrelia-positive samples were tested by nested PCR for the <i>B. miyamotoi</i> and <i>B. burgdorferi</i> s.l. DNA. <b>Results</b>. <i>B. miyamotoi</i> DNA was detected in the CSF of one (0.8%) patient. DNA of <i>B. burgdorferi</i> s.l. was not found in any samples. <b>Conclusions</b>. Detection of the <i>B. miyamotoi</i> in patients with central nervous system infections expand the development of knowledge on infections caused by Borrelia spirochetes.</p>","PeriodicalId":50970,"journal":{"name":"Annals of Agricultural and Environmental Medicine","volume":"32 1","pages":"142-145"},"PeriodicalIF":1.3,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143755822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Attitudes of Poles and Belarusians towards older people - a cross-cultural study.","authors":"Jacek Łukasiewicz, Wiesław Kowalski, Maria Malm","doi":"10.26444/aaem/193620","DOIUrl":"https://doi.org/10.26444/aaem/193620","url":null,"abstract":"<p><strong>Introduction and objective: </strong>Attitudes toward seniors are indicators of the quality of relations in society. Nationality and place of residence may be the factors that differentiate these attitudes. The aim of the study was to discover whether there are differences in attitudes towards seniors depending on the place of residence and nationality, with reference to Poland-Belarus.</p><p><strong>Material and methods: </strong>The study included a group of 881 people (527 Poles and 354 Belarusians) with the variable of place of residence. The Scale of Attitudes Toward Seniors (SPWS) developed by J. Lukasiewicz and W. Kowalski was used.</p><p><strong>Results: </strong>Poles scored significantly higher than Belarusians on the Respect and Support scale - 4.60 ± 0.59 versus 4.39 ± 0.64 (p<0.001), as well as on the Rejection and Misunderstanding scale - 3.62 ± 0.66 versus 3.45 ± 0.63 (p<0.001). In contrast, on the Social Distance scale, Belarusians had average scores of 2.91 ± 0.56, which were significantly higher than those of Poles (p<0.001). Two-factor ANOVA also showed statistically significant differences on the Respect and Support scale, taking into consideration nationality (p=0.005) and place of residence (p<0.001), as well as in the Rejection and Misunderstanding scale by nationality (p=0.001). There were no statistically significant differences in the Rejection and Misunderstanding scale by place of residence (p=0.664).</p><p><strong>Conclusions: </strong>Improving the quality of life and standards of care for the elderly is conducive to shaping positive attitudes between generations. Cultural patterns, such as the image of the family and ways of communication in intergenerational relationships, are important for building the correct image of older people and their role in society. Awareness of the changes that occur in old age may be important for shaping the positive image of seniors among the young generation.</p>","PeriodicalId":50970,"journal":{"name":"Annals of Agricultural and Environmental Medicine","volume":"32 1","pages":"127-132"},"PeriodicalIF":1.3,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143755801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Joanna Błajda, Marta Kopańska, Edyta Małgorzata Barnaś
{"title":"Analysis of Google Trends reflecting interest of Internet users in topics related to breast cancer and its prevention in Poland, 2013-2023.","authors":"Joanna Błajda, Marta Kopańska, Edyta Małgorzata Barnaś","doi":"10.26444/aaem/190672","DOIUrl":"https://doi.org/10.26444/aaem/190672","url":null,"abstract":"<p><strong>Introduction and objective: </strong>Breast cancer is the most commonly diagnosed cancer in women, both in Poland and globally. Despite the increasing incidence of breast cancer and the increase in research on Google Trends, there is little research on the application of this tool regarding oncology topics using key words in Polish. There is also a lack of research that focuses explicitly on breast cancer and prevention key words, which creates a need to fill this gap. The aim of the study is to analyse trends in Internet user interest in breast cancer and prevention in Poland between 2013-2023, based on the Google Trends tool.</p><p><strong>Material and methods: </strong>An analysis of search terms used by Polish Internet users for topics related to breast cancer and prevention in 2013-2023, using the Google Trends tool.</p><p><strong>Results: </strong>Significant changes in the interest of Polish Internet users in selected issues related to breast cancer and its prevention in Poland between 2013 and 2023 were demonstrated. A clear decrease in interest in the key words was noted in the initial period of the COVID-19 pandemic.</p><p><strong>Conclusions: </strong>A clear upward trend was shown between 2013-2023 in Poland in interest in the key words: 'mammography', 'breast ultrasound', 'breast examination', 'MRI', and 'breast biopsy'. The lowest interest for 9 of the 14 key words was recorded in April 2020 at the start of the COVID-19 pandemic. For 7 of the 14 key words, the highest interest (100 on the GT scale) was recorded in the month of October. Google Trends can be used to track public interest in breast cancer and screening in real time.</p>","PeriodicalId":50970,"journal":{"name":"Annals of Agricultural and Environmental Medicine","volume":"32 1","pages":"79-84"},"PeriodicalIF":1.3,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143755827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marek Mazurek, Natalia Lehman, Filip Stoma, Gabriela Czaja, Agata Banach, Bożena Jarosz, Radosław Rola
{"title":"How 5-ALA enlightens neurosurgery - results of a single centre study on high-grade gliomas.","authors":"Marek Mazurek, Natalia Lehman, Filip Stoma, Gabriela Czaja, Agata Banach, Bożena Jarosz, Radosław Rola","doi":"10.26444/aaem/194075","DOIUrl":"https://doi.org/10.26444/aaem/194075","url":null,"abstract":"<p><strong>Introduction and objective: </strong>This study aims to assess the effectiveness of the use of intraoperative fluorescence with 5-ALA on the scope on the resection and the results of the treatment of patients. Despite the continuous development of new oncological treatments, surgical resection remains the basis for treating high-grade gliomas. For this reason, methods are introduced to facilitate the removal of the tumour in a maximally complete and safe manner for the patient.</p><p><strong>Material and methods: </strong>The effects were examined of intraoperative fluorescence using 5-aminolevulinic acid (5-ALA). The volumetric extent of resection and the outcome of 39 cases of patients with high-grade gliomas operated on using intraoperative fluorescence were compared with 5-ALA and patients undergoing resection using a white-light microscope.</p><p><strong>Results: </strong>The use of 5-ALA during the procedure increased the extent of resection compared to procedures under white light: - 96.14% vs. 90.69%. Interestingly, when focused on recurrent high-grade gliomas, better results were observed for the white-light group. There was also an improvement in the overall survival (OS) of patients operated on with 5-ALA (p=0.0485). OS for the study group was 9.97 months compared to 6.40 months for the control group.</p><p><strong>Conclusions: </strong>Based on the observations, the use of 5-ALA in surgery for high-grade gliomas allows for an increase in the extent of resection performed and an improvement in patient prognosis. Moreover, the use of 5-ALA shows better results for primary tumours when compared to recurrent ones (p<0.0001 for primary gliomas).</p>","PeriodicalId":50970,"journal":{"name":"Annals of Agricultural and Environmental Medicine","volume":"32 1","pages":"133-141"},"PeriodicalIF":1.3,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143755807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Konstantyn Babov, Alona Kysylevska, Alexander Plakida, Lidia Elżbieta Sierpińska, Iryna Zabolotna, Sergey Gushcha
{"title":"The use of mineral waters in rehabilitating patients with coronavirus disease - a review.","authors":"Konstantyn Babov, Alona Kysylevska, Alexander Plakida, Lidia Elżbieta Sierpińska, Iryna Zabolotna, Sergey Gushcha","doi":"10.26444/aaem/196916","DOIUrl":"https://doi.org/10.26444/aaem/196916","url":null,"abstract":"<p><strong>Introduction and objective: </strong>The review aimed to consider evidence of the effectiveness of using mineral waters in the rehabilitation of patients who have had a coronavirus disease.</p><p><strong>Review methods: </strong>The study was registered on PROSPERO (CRD42023438740). Relevant studies were systematically reviewed, based on randomized controlled trials with meta-analysis that included at least one group receiving mineral waters (MW). General scientific papers and regulatory documents on health care in Ukraine, including rehabilitation and resort resources, and rehabilitation protocols after the coronavirus disease, were also used for the analysis. Search for articles and other scientific works published in English and Ukrainian from 1994 to 5 February 2023, was conducted in the following databases: Pubmed, Web of Science, and Scopus. Dual data abstraction, quality assessment, and strength of evidence was also performeds. The results were evaluated of using various mineral waters in the rehabilitation of patients with complications of COVID-19 disease.</p><p><strong>Brief description of the state of knowledge: </strong>Most of the studies (28%) are devoted to the use of mineral waters for complications of the respiratory system. 12% of papers were devoted to the pathology of the musculoskeletal system, 10% to chronic fatigue (asthenia), anxiety-depressive, and other neuropsychiatric disorders, 9% to еру cardiovascular system, and 8% to dermatological problems.</p><p><strong>Summary: </strong>Differentiated use of balneotherapy, considering the composition of MW, temperature, and the frequency of their application, allows for increasing the effectiveness of rehabilitation of post-Covid-19 complications of various organs and systems of the body.</p>","PeriodicalId":50970,"journal":{"name":"Annals of Agricultural and Environmental Medicine","volume":"32 1","pages":"20-26"},"PeriodicalIF":1.3,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143754922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Honey varieties vs metal and pesticide content - literature review and own research.","authors":"Małgorzata Gałczyńska, Renata Gamrat, Małgorzata Puc","doi":"10.26444/aaem/197247","DOIUrl":"https://doi.org/10.26444/aaem/197247","url":null,"abstract":"<p><strong>Introduction and objective: </strong>Although monofloral honeys are regarded as more valuable than multifloral types, they lack a clear uniform definition in European countries concerning the proportions of predominant pollen types. In addition, honey contains various secondary plant metabolites, enzymes and co-enzymes, which provide health-promoting properties; however, it can also accumulate heavy metals and pesticide residues.</p><p><strong>Review methods: </strong>A literature review was performed using the databases PubMed, Google Scholar concerning the content of metals in the soil, flower and bee pollen in varietal honey. Literature was collected on the influence of pesticides contained in honey on their impact on the human health. Own research selected three varieties of Polish monofloral honey (linden, black locust, rapeseed), which were analyzed using a spectrometer to determine the concentration Ca, Cu, Fe, K, Mg, Mn, Na, Zn.</p><p><strong>Brief description of the state of knowledge: </strong>Literature data indicate that a polluted or treated environment can contribute to the accumulation of <i>inter alia</i> heavy metals and pesticides in pollen, honey, beeswax, and the honeybee itself. Such contamination is influenced by various environmental factors, e.g. contaminants from the flower can be passed to the bee though contact with contaminated pollen and incorporated in honey. However, in the monofloral honeys analysed in this study, there were combinations of health-promoting elements that exert synergistic effects.</p><p><strong>Summary: </strong>The results obtained provide new qualitative and quantitative data on the composition and potential contamination of varietal honeys over the past 10 years, a period characterised by legislative changes aimed at reducing pesticide and metal contamination of terrestrial ecosystems.</p>","PeriodicalId":50970,"journal":{"name":"Annals of Agricultural and Environmental Medicine","volume":"32 1","pages":"9-19"},"PeriodicalIF":1.3,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143755806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}