Annales De Pathologie最新文献

{"title":"Réseau RENAPE : vers une meilleure équité d’accès aux soins et à l’expertise pour les patients atteints de cancers rares du péritoine","authors":"","doi":"10.1016/j.annpat.2024.05.003","DOIUrl":"10.1016/j.annpat.2024.05.003","url":null,"abstract":"<div><p>Crée en 2010, avec le soutien de l’Institut national du cancer et de la direction générale de l’offre de soins, le Réseau national de prise en charge des tumeurs rares du péritoine (RENAPE) s’est progressivement structuré et densifié et a permis d’optimiser les filières de soins impliquées dans le traitement des cancers rares du péritoine. Au sein du réseau, le groupe RENA-PATH s’est lui aussi développé en répondant à sa mission d’expertise diagnostique anatomopathologique, mais aussi en s’interfacant avec le groupe MESOPATH. Par ailleurs, les groupes RENAPE et RENA-PATH ont participé à la diffusion de bonnes pratiques en s’intégrant en 2019 au Thesaurus National de Cancérologie Digestive (TNCD) et en participant à de nombreux enseignements de formation post-universitaire. Cet article a pour but de rappeler de façon synthétique, les missions de RENAPE et RENA-PATH, notamment l’équité d’accès à l’expertise, et de souligner leur évolution.</p></div><div><p>Since its creation in 2010, the progressive structuration of the RENAPE network (Réseau national de prise en charge des tumeurs rares du péritoine) supported by the “Institut national du cancer” and the “Direction générale de l’offre de soins”, allowed the optimization of the healthcare system involved in the management of the rare cancers of the peritoneum. In this setting, the RENA-PATH group has also been reinforced, notably by its recognized diagnostic expertise in pathology and its interface with the MESOPATH group. Moreover RENAPE and RENA-PATH led to guidelines diffusion through the integration, in 2019, to the ``Thesaurus National de Cancérologie Digestive'' (TNCD) and to post-university medical education programs. The aim of this article is to highlight the missions of the RENAPE and RENA-PATH, notably the equity in terms of expertise, access to the networks and their improvement in the management of peritoneal diseases.</p></div>","PeriodicalId":50969,"journal":{"name":"Annales De Pathologie","volume":"44 4","pages":"Pages 291-295"},"PeriodicalIF":0.5,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141263229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Histoséminaire biopsies péritonéales tumorales. Cas no 2","authors":"","doi":"10.1016/j.annpat.2024.06.004","DOIUrl":"10.1016/j.annpat.2024.06.004","url":null,"abstract":"","PeriodicalId":50969,"journal":{"name":"Annales De Pathologie","volume":"44 4","pages":"Pages 245-251"},"PeriodicalIF":0.5,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141545429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Cutaneous adnexal tumours: Development and synthesis of diagnostic fusion genes].","authors":"Thibault Kervarrec, Maxime Battistella, Nicolas Macagno","doi":"10.1016/j.annpat.2024.05.002","DOIUrl":"https://doi.org/10.1016/j.annpat.2024.05.002","url":null,"abstract":"<p><p>Cutaneous adnexal tumours are a heterogeneous group of epithelial lesions that includes tumours with follicular, sudoral and/or sebaceous differentiation, or even several combined lines of differentiation. Over the last few years, molecular analysis of these lesions has allowed to identify specific molecular events responsible for tumour development in an increasing number of tumour types. Like other rare neoplasms, such as soft tissue tumours, adnexal tumours display fusion genes resulting from chromosomal translocations that may be specific for the diagnosis if molecular data are properly integrated in the clinical and morphological setting. Molecular testing of adnexal tumours is valuable as it allows to strengthen the robustness of the diagnosis for a group of tumours displaying a wide morphological spectrum. It has allowed to refine the diagnostic criteria and to develop increasingly specific diagnostic immunostainings. Finally, molecular testing has been responsible for the identification of new entities or morphological subtypes of previously known entities. The aim of this review is to provide an update on cutaneous adnexal tumours associated with fusion genes and to evaluate the impact of molecular data on the diagnosis of these lesions.</p>","PeriodicalId":50969,"journal":{"name":"Annales De Pathologie","volume":" ","pages":""},"PeriodicalIF":0.5,"publicationDate":"2024-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141263214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[About a case of primary laryngeal mucosal melanoma in a patient with medical history of oropharyngeal squamous carcinoma].","authors":"Alice Michaut, Guillaume Clair, Edouard Hanau, Julia Ratour, Ollivier Laccoureye, Cécile Badoual","doi":"10.1016/j.annpat.2024.04.017","DOIUrl":"https://doi.org/10.1016/j.annpat.2024.04.017","url":null,"abstract":"<p><strong>Introduction: </strong>Primary laryngeal mucosal melanoma is a rare tumour with a poor prognosis. Its often difficult diagnosis should rule out laryngeal metastatic localization of cutaneous melanoma.</p><p><strong>Case presentation: </strong>We report a case of primary laryngeal mucosal melanoma diagnosed in a 65-year-old man, treated 6 years previously with radio-chemotherapy and surgery for squamous cell carcinoma of the right lateral oropharyngeal region. The definitive diagnosis of primary laryngeal mucosal melanoma was made on the resection specimen, whereas the initial biopsy of the epilaryngeal mass discovered during the patient's surveillance had concluded that it was a laryngeal recurrence of the known squamous cell carcinoma.</p><p><strong>Discussion: </strong>Through this case, we propose to remind the main characteristics and the diagnostic pitfalls of these tumours.</p>","PeriodicalId":50969,"journal":{"name":"Annales De Pathologie","volume":" ","pages":""},"PeriodicalIF":0.5,"publicationDate":"2024-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141263212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synovialosarcome primitif du rein : si tout était déjà dans les urines pyéliques ?","authors":"Fidélia Da Silva ,&nbsp;Géraldine Saada-Sebag ,&nbsp;Anne Mc Leer ,&nbsp;Catherine Meilhac-Fournier ,&nbsp;Séverine Valmary-Degano ,&nbsp;Diane Giovannini","doi":"10.1016/j.annpat.2023.12.002","DOIUrl":"10.1016/j.annpat.2023.12.002","url":null,"abstract":"<div><p>Le synovialosarcome est une tumeur mésenchymateuse maligne de l’adulte jeune, qui survient dans les tissus mous profonds, en particulier autour des grosses articulations. Lorsqu’il survient dans des sites plus inhabituels, il peut représenter alors un défi diagnostique important. Nous rapportons le cas d’une adolescente de 19 ans prise en charge pour une masse pyélique dont la cytologie urinaire pyélique faite simultanément à une biopsie pyélique s’est avérée être un élément d’orientation non négligeable et parfaitement concordant avec l’aspect histopathologique de la masse pyélique après néphrectomie. Nous rapportons ici le premier cas de synovialosarcome rénal documenté dans des urines pyéliques.</p></div><div><p>Synovialosarcoma is a malignant mesenchymal tumor of young adults that occurs in the deep soft tissues, particularly around large joints. When it occurs in more unusual sites, it could present a significant diagnostic challenge. In this case, a 19-year-old girl was treated for a pyloric mass. A pyelic urine cytology performed simultaneously with a pyloric biopsy proved to be a significant element of orientation and perfectly concordant with the histopathological aspect of the pyelic mass after nephrectomy. We report here the first case of renal synovialosarcoma documented in pyelic urine.</p></div>","PeriodicalId":50969,"journal":{"name":"Annales De Pathologie","volume":"44 3","pages":"Pages 204-209"},"PeriodicalIF":0.5,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139717970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Un « lâcher de ballons » faussement inquiétant !","authors":"Arnault Tauziède-Espariat ,&nbsp;Bertrand Grand ,&nbsp;Ali Benali ,&nbsp;Marie Georges ,&nbsp;Thomas Rialland ,&nbsp;Odette Georges","doi":"10.1016/j.annpat.2024.02.008","DOIUrl":"10.1016/j.annpat.2024.02.008","url":null,"abstract":"","PeriodicalId":50969,"journal":{"name":"Annales De Pathologie","volume":"44 3","pages":"Pages 218-221"},"PeriodicalIF":0.5,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140050964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"La version 2022 du Système de Paris : quoi de neuf ?","authors":"Monique Courtade-Saïdi","doi":"10.1016/j.annpat.2023.12.010","DOIUrl":"10.1016/j.annpat.2023.12.010","url":null,"abstract":"<div><p>La deuxième version du Système de Paris pour rapporter la cytologie urinaire a été publiée en 2022. Elle fait suite à la première version de 2016 qui a connu un grand succès et été largement adoptée par de nombreux cytopathologistes de différents pays. Ainsi, de nombreuses publications utilisant le Système de Paris ont permis d’affiner les critères et d’en discuter les limites. L’accent est mis sur la pertinence de la cytologie urinaire pour la détection du carcinome urothélial de haut grade, mais pas pour celui de bas grade qui ne présente que peu d’anomalies cytologiques. Ainsi, le chapitre individualisant les néoplasmes urothéliaux de bas grade a été supprimé, ces derniers ont été inclus dans la catégorie négative pour le carcinome urothélial de haut grade. Le risque de malignité est remplacé par le risque de carcinome urothélial de haut grade, seul détectable de façon fiable en cytologie. Un nouveau chapitre a été consacré aux tumeurs urothéliales du haut appareil. Enfin, les pièges liés à la dégénérescence cellulaire sont discutés pour chacune des catégories. Le risque de carcinome urothélial de haut grade associé à chaque catégorie va faciliter la communication avec le clinicien et la prise en charge des patients.</p></div><div><p>The second version of the Paris System for reporting urine cytology was published in 2022. It follows the first version of 2016, which was very successful and widely adopted by many cytopathologists from different countries. Thus, numerous publications using the Paris System have made possible to refine the criteria as well as discussing the limits. The diagnostic accuracy of urinary cytology is high for detection of high-grade urothelial carcinoma, but not for low-grade carcinoma where there are few cytological abnormalities. So, the chapter individualizing low-grade urothelial neoplasms was deleted; the latter were included in the category “negative for high-grade urothelial carcinoma”. Indeed, the risk of malignancy is replaced by the risk of high-grade urothelial carcinoma. A new chapter has been devoted to urothelial tumors of the upper tract. Finally, the pitfalls linked to cellular degeneration are discussed for each category. The risk of high-grade malignancy associated with each category will help communication with the clinician and help patient care.</p></div>","PeriodicalId":50969,"journal":{"name":"Annales De Pathologie","volume":"44 3","pages":"Pages 188-194"},"PeriodicalIF":0.5,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139503108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Revue de presse","authors":"Audrey Rousseau","doi":"10.1016/j.annpat.2024.04.002","DOIUrl":"10.1016/j.annpat.2024.04.002","url":null,"abstract":"","PeriodicalId":50969,"journal":{"name":"Annales De Pathologie","volume":"44 3","pages":"Pages 156-158"},"PeriodicalIF":0.5,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140760424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Un carcinome basocellulaire avec différenciation myoépithéliale","authors":"Claire David,&nbsp;Antoine Taillandier,&nbsp;Paul-Louis Chantreau,&nbsp;Rémy Kerdraon,&nbsp;Flore Delalande,&nbsp;Patrick Michenet","doi":"10.1016/j.annpat.2024.02.004","DOIUrl":"10.1016/j.annpat.2024.02.004","url":null,"abstract":"","PeriodicalId":50969,"journal":{"name":"Annales De Pathologie","volume":"44 3","pages":"Pages 215-217"},"PeriodicalIF":0.5,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140050965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tumeurs des glandes salivaires : OMS 2022 et au-delà","authors":"Charles Lépine","doi":"10.1016/j.annpat.2024.02.005","DOIUrl":"10.1016/j.annpat.2024.02.005","url":null,"abstract":"<div><p>En 2022, la 5^e édition de la classification des tumeurs de la tête et du cou a été publiée en ligne par l’OMS. Dans le chapitre des glandes salivaires, on trouve tout d’abord une nouvelle entité bénigne : le kératocystome. L’adénose sclérosante polykystique a été reconnue comme tumorale et s’appelle désormais l’adénome sclérosant polykystique. L’adénome des canaux striés a maintenant son propre chapitre. Enfin, il a également été intégré un nouveau variant d’adénome pléomorphe « adénome canaliculaire-like ». Du côté des tumeurs malignes des glandes salivaires, il est maintenant souligné les doutes sur la réelle existence du carcinome oncocytaire, qui a donc été reclassé dans les entités émergentes. Deux nouvelles entités malignes ont également fait leur apparition : l’adénocarcinome microsécrétoire et l’adénocarcinome sclérosant microkystique. Enfin, l’adénocarcinome mucineux primitif des glandes salivaires a été reconnu comme entité à part entière.</p></div><div><p>In 2022, the 5th edition of the WHO classification of Head and Neck tumors was published online. In the salivary gland chapter, a new benign entity, the keratocystoma, was introduced. The sclerosing polycystic adenosis has been recognized as tumoral and is now termed sclerosing polycystic adenoma. The striated duct adenoma now has its own dedicated chapter. Additionally, a new variant of pleomorphic adenoma, termed “canalicular adenoma-like,” has been incorporated. Regarding malignant tumors of the salivary glands, significant doubts now exist regarding the actual existence of oncocytic carcinoma, which has been reclassified among emerging entities. Two new malignant entities have also emerged: microsecretory adenocarcinoma and microcystic sclerosing adenocarcinoma. Finally, primary mucinous adenocarcinoma of the salivary glands has been acknowledged as a distinct entity.</p></div>","PeriodicalId":50969,"journal":{"name":"Annales De Pathologie","volume":"44 3","pages":"Pages 175-182"},"PeriodicalIF":0.5,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0242649824000464/pdfft?md5=c70a943b7f2b6ef8718bcbc3e6143acc&pid=1-s2.0-S0242649824000464-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140050968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}