{"title":"Regulation of Fatty Acid Metabolism Defines Distinct Molecular Subtypes in Stomach Adenocarcinoma: Implications for Tumor Microenvironment and Precision Therapeutics","authors":"Yuntong Zhang , Qi Xie , Youhui Wang , Lin Wang","doi":"10.1016/j.amepre.2025.107873","DOIUrl":"10.1016/j.amepre.2025.107873","url":null,"abstract":"<div><h3>Introduction</h3><div>Stomach adenocarcinoma (STAD) is a major global gastrointestinal malignancy, significantly impacting morbidity and mortality rates worldwide. Advances in lipidomics and metabolomics shed light on fatty acid metabolism's role in various malignancies, including STAD. However, the specific influence of fatty acid metabolism-related genes (FAMGs) on STAD's therapeutic response remains unclear.</div></div><div><h3>Methods</h3><div>This work merged high-dimensional datasets from TCGA and GEO to assess FAMGs' predictive value in STAD. These datasets encompassed molecular variables (mRNAsi, genomic mutations, CNV, TMB), enabling the construction of a robust predictive model via Lasso regression. Co-expression network analysis delineated FAMGs' functional roles and therapeutic implications.</div></div><div><h3>Results</h3><div>FAMGs were consistently overexpressed in high-risk STAD, suggesting their potential as prognostic biomarkers. High-risk groups displayed enrichment in immunological and tumor-associated pathways. Candidate genes (APOD, FLRT2, MMRN1, CD36) surfaced as potential contributors to STAD's oncogenic basis. Immunological processes and m6a gene expression varied across risk strata, emphasizing divergent prognostic trajectories. The predictive model showed strong associations with genomic features and drug susceptibility profiles.</div></div><div><h3>Discussion</h3><div>FAMGs play a crucial role in STAD pathogenesis and clinical course. The derived FAMG signature serves as a potent prognostic tool and paves the way for targeted therapeutic research in STAD.</div></div>","PeriodicalId":50805,"journal":{"name":"American Journal of Preventive Medicine","volume":"69 2","pages":"Article 107873"},"PeriodicalIF":4.5,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144723406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Efficacy of Laparoscopic Surgery with Choledochoscopic Transcystic Approach for Gallbladder and Common Bile Duct Stones","authors":"Xiuhan Jiang , Saihua Li , Jianfa Zhang, Peng Li","doi":"10.1016/j.amepre.2025.107899","DOIUrl":"10.1016/j.amepre.2025.107899","url":null,"abstract":"<div><h3>Background and Objective</h3><div>Current treatments for gallbladder stones with common bile duct stones (CBDS) include laparoscopic common bile duct exploration (LCBDE) and ERCP with laparoscopic cholecystectomy (ERCP+LC). However, LCBDE often requires T-tube drainage or primary suture, altering biliary anatomy, while ERCP+LC risks Oddi sphincter dysfunction. This study utilized cystic duct-based stone extraction to avoid bile duct injury and sphincter incision. To evaluate laparoscopic transcystic choledochoscopic stone removal (LT-CBDE) for cholecystolithiasis with CBDS and its clinical efficacy.</div></div><div><h3>Subjects and Methods</h3><div>From 2019 to 2024, 560 patients at Yellow River Sanmenxia Hospital were divided into LT-CBDE (n=280) and LCBDE with primary suture (n=280) groups. Outcomes included stone clearance, bile leakage, choledochoscopy duration, suture time, blood loss, and hospital stay.</div></div><div><h3>Results</h3><div>LT-CBDE showed no significant difference in postoperative residual stone rate compared to LCBDE (0.7% vs. 0.4%, <em>p</em>=0.563) but demonstrated superior outcomes: significantly lower bile leakage incidence (0.7% vs. 13.6%, <em>p</em><0.001), reduced biliary suturing time (4.6 ± 1.4 vs. 6.4 ± 1.1 min, <em>p</em><0.05), shorter postoperative hospitalization (2.9 ± 1.4 vs. 7.0 ± 1.4 days, <em>p</em>< 0.05), and lower hospitalization costs (7,425 ± 858 vs. 15,033 ± 573 RMB, <em>p</em><0.05). Technical proficiency correlated with further optimization of operative efficiency and clinical outcomes.</div></div><div><h3>Conclusions</h3><div>Laparoscopic common bile duct exploration via the cystic duct approach is an effective method for treating common bile duct stones. By strengthening health education, promoting healthy lifestyles, and implementing early screening and intervention, we can effectively reduce the disease burden of common bile duct stones and achieve a shift from \"treating disease\" to \"preventing disease.\" Deepening the concept of preventive medicine can further reduce disease incidence and improve population health outcomes.</div></div>","PeriodicalId":50805,"journal":{"name":"American Journal of Preventive Medicine","volume":"69 2","pages":"Article 107899"},"PeriodicalIF":4.5,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144723421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Practical Research on the Promotion of College Students' Physical and Mental Health Through the Integration of Tai Chi and Traditional Chinese Medicine Theory","authors":"Fei Yang, Yanfang Dong","doi":"10.1016/j.amepre.2025.107901","DOIUrl":"10.1016/j.amepre.2025.107901","url":null,"abstract":"<div><h3>Background</h3><div>Contemporary university students are facing increasing academic and employment pressures, leading to prominent psychological issues such as anxiety and emotional instability, which has sparked concern over interventions for physical and mental health. Tai Chi, a traditional Chinese exercise, emphasizes harmony between the mind and body. Through slow and deliberate movements combined with breath regulation, it is believed to contribute to the improvement of physical and mental health.</div></div><div><h3>Subjects and Methods</h3><div>This study employed a randomized controlled trial, who were divided into an experimental group and a control group, each consisting of 50 participants. Data was collected through standardized questionnaires, body composition tests, and cardiopulmonary function assessments. Mental health evaluations were conducted using the GAD-7 and CD-RISC scales, with SPSS utilized for statistical analysis of pre-and post-intervention results.</div></div><div><h3>Results</h3><div>The study found that the Tai Chi group demonstrated significant improvements in both physical and mental health. Positive changes were observed in body composition indicators, and cardiopulmonary function indicators also showed improvement. The benefits in terms of mental health were evident, with a significant reduction in anxiety levels and a marked increase in psychological resilience.</div></div><div><h3>Conclusions</h3><div>This study, integrating traditional Chinese medicine theory, Tai Chi provides a holistic approach to addressing health challenges, capable of reducing anxiety, enhancing psychological resilience, and improving physical fitness. It underscores the potential of Tai Chi as a tool in fostering a healthy campus culture and offers theoretical and practical references for promoting the health of college students through traditional wellness practices in the future.</div></div>","PeriodicalId":50805,"journal":{"name":"American Journal of Preventive Medicine","volume":"69 2","pages":"Article 107901"},"PeriodicalIF":4.5,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144723123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Relationship between Contrast-Enhanced Ultrasound Characteristics of Carotid Plaques, Carotid Stenosis Severity, and Transient Ischemic Attack","authors":"Bohan Liu","doi":"10.1016/j.amepre.2025.107902","DOIUrl":"10.1016/j.amepre.2025.107902","url":null,"abstract":"<div><h3>Introduction</h3><div>To investigate the correlation between contrast-enhanced ultrasound (CEUS) characteristics of carotid plaques, degree of carotid stenosis, and transient ischemic attack (TIA), and to establish a risk stratification model based on a preventive medicine framework for guiding clinical interventions.</div></div><div><h3>Method</h3><div>A retrospective study was conducted on 112 patients with carotid atherosclerosis from January 2020 to June 2023, categorized into mild (<50%), moderate (50%-70%), and severe (>70%) stenosis groups. CEUS was used to evaluate plaque enhancement patterns (homogeneous/heterogeneous) and intraplaque neovascularization grades (0-III). Associations with stenosis severity and TIA incidence were analyzed by integrating preventive medicine risk factors (blood pressure, lipid levels, smoking history).</div></div><div><h3>Results</h3><div>The severe stenosis group showed significantly higher proportions of heterogeneous enhancement (78.3% vs. 42.1%) and grade III neovascularization (65.2% vs. 15.8%) compared to the mild group (P<0.01). Multivariate logistic regression identified heterogeneous enhancement (OR=3.12, 95%CI 1.45-6.71) and grade III neovascularization (OR=4.85, 95%CI 2.33-10.09) as independent risk factors for TIA. ROC analysis demonstrated that combining CEUS parameters with preventive medicine indicators (Framingham Risk Score) improved the AUC for TIA prediction to 0.91 (sensitivity 86.7%, specificity 83.2%).</div></div><div><h3>Discussion</h3><div>CEUS characteristics effectively assess carotid plaque vulnerability and correlate with stenosis severity and TIA occurrence, providing imaging evidence for early clinical intervention. The established \"imaging-clinical\" risk stratification model (low, intermediate, high risk) provides guidance for preventive medicine practice.</div></div>","PeriodicalId":50805,"journal":{"name":"American Journal of Preventive Medicine","volume":"69 2","pages":"Article 107902"},"PeriodicalIF":4.5,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144723133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Construction of Rural Public Health Service Systems and Evaluation of Infectious Disease Prevention Effectiveness","authors":"Xiaofang Li","doi":"10.1016/j.amepre.2025.107900","DOIUrl":"10.1016/j.amepre.2025.107900","url":null,"abstract":"<div><h3>Introduction</h3><div>To investigate pathways for public health service system development and assess epidemic prevention efficacy in rural areas, integrating dual perspectives of regional development and public health demands.</div></div><div><h3>Method</h3><div>A multidimensional evaluation framework covering 24 rural demonstration sites was established through integration of cross-sectional data and spatiotemporal panel data. The Analytic Hierarchy Process (AHP) was employed to determine health resource allocation priorities, while the Spatial Durbin Model was utilized to elucidate spatial correlation characteristics of disease transmission.</div></div><div><h3>Results</h3><div>A 10% enhancement in public health system completeness reduced incidence rates by 6.8-9.2% (95% CI: 5.4-11.3). Key driving factors included graded diagnosis and treatment coverage (β=0.412), digital surveillance response timeliness (β=0.357), and interdepartmental coordination efficiency (β=0.285). Spatial econometric analysis revealed that one standard deviation increase in medical accessibility decreased neighborhood incidence by 0.37 standard deviations (Moran’s I=0.216, p<0.05), with tourist flow threshold (>38,000 persons/month) demonstrating negative regulatory effects (γ=-0.154).</div></div><div><h3>Discussion</h3><div>This study proposes establishing early warning mechanisms and intelligent surveillance systems, coupled with dynamic health resource-regional demand alignment strategies, to effectively enhance rural public health resilience and develop replicable prevention models.</div></div>","PeriodicalId":50805,"journal":{"name":"American Journal of Preventive Medicine","volume":"69 2","pages":"Article 107900"},"PeriodicalIF":4.5,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144723176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Impact of Distribution Contract Types on the Adoption of Blockchain Strategies by Competitive Brand Sellers in the Field of Public Health","authors":"Zemin Luo, Min Bao, Jingpei Ma, Yujuan Gao","doi":"10.1016/j.amepre.2025.107881","DOIUrl":"10.1016/j.amepre.2025.107881","url":null,"abstract":"<div><h3>Introduction</h3><div>This research delves into the transformative role of blockchain technology within a dual-channel supply chain framework, emphasizing its influence on enhancing product transparency in the public health domain. By ensuring the traceability and authenticity of health-related products, blockchain can significantly alter the pricing dynamics for brand manufacturers. The study explores how increased transparency can lead to more informed consumer choices, potentially affecting demand patterns and, consequently, the pricing strategies adopted by brand sellers. Ultimately, the research aims to understand how these pricing adjustments impact the overall profitability and market position of these sellers within the public health sector.</div></div><div><h3>Method</h3><div>This research uses a model consisting of a platform and upstream brand sellers, focusing on public health products. It analyzes the cost-effectiveness of brand sellers adopting blockchain technology in two channels: direct sales and platform sales, as well as the choice of public health products between two sales models: wholesale and agency.</div></div><div><h3>Results</h3><div>The study finds that in the field of public health, the cost of adopting blockchain technology has a significant impact on the decision-making of brand sellers. Under low-cost conditions, brand sellers tend to adopt blockchain to improve the transparency of public health products, which can not only attract health-conscious consumers but also increase market share and enhance brand image. The level of on-chain costs also affects the choice of brand sellers between wholesale and agency models, as well as the pricing strategy of public health products. Under the wholesale model, lower retail prices and higher demand help to increase the profits of brand sellers in public health products.</div></div><div><h3>Discussion</h3><div>We found that the type of distribution contract has a profound impact on the adoption of blockchain strategies by competitive brand sellers in the field of public health. Brand sellers need to choose appropriate sales models and blockchain application strategies based on their own situations and market environments to enhance the transparency of public health products, attract consumers, increase market share, and improve brand image. At the same time, governments and relevant institutions should also actively promote the application and development of blockchain technology in the field of public health to ensure public health and safety.</div></div>","PeriodicalId":50805,"journal":{"name":"American Journal of Preventive Medicine","volume":"69 2","pages":"Article 107881"},"PeriodicalIF":4.5,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144723349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Low-Carbon Transit-Oriented Development and Active Transportation Modes: A Mixed-Methods Study on Mitigating Urban Heat Island Effects and Heat-Related Diseases","authors":"Jingyi Wang , Ting Yang , Haowen Xu , Zhiqiang Wu","doi":"10.1016/j.amepre.2025.107926","DOIUrl":"10.1016/j.amepre.2025.107926","url":null,"abstract":"<div><h3>Introduction</h3><div>To evaluate the impact of low-carbon transit-oriented development (TOD) and active transportation modes (e.g., cycling, walking) on urban heat island (UHI) mitigation and the prevention of heat-related diseases in densely populated areas.</div></div><div><h3>Method</h3><div>A mixed-methods approach combined land use data, meteorological records, and health surveys across 12 neighborhoods in a metropolitan area. Thermal infrared imaging and geographic information systems (GIS) assessed UHI intensity (ΔT = urban-l rural temperature difference). Heat-related illness incidence (e.g., heatstroke, dehydration) was analyzed via hospital admissions (2018–2023). Intervention scenarios simulated TOD strategies (e.g., green corridors, expanded bike lanes) using ENVI-met modeling. Community engagement surveys (n=400 residents) evaluated behavioral shifts in mobility patterns and thermal comfort perceptions.</div></div><div><h3>Results</h3><div>Neighborhoods with TOD infrastructure showed 1.8–2.3°C lower ΔT compared to conventional zones (p<0.01). Increased active transportation usage correlated with a 37% reduction in heat-related hospitalizations (adjusted OR=0.63, 95% CI: 0.51–0.78). Green corridor implementation reduced surface temperatures by 2.1°C (p<0.05) and enhanced pedestrian thermal comfort. Survey data indicated 68% of residents adopted heat-mitigating behaviors (e.g., hydration, shaded routes) post-intervention.</div></div><div><h3>Discussion</h3><div>Integrating low-carbon TOD with active transportation significantly reduces UHI effects and heat-related disease risks. These findings support preventive public health strategies by promoting urban designs that combine thermal comfort, emission reductions, and equitable health outcomes. Policymakers should prioritize TOD-expanded green spaces and safe cycling networks to mitigate climate-health synergies in vulnerable populations.</div></div>","PeriodicalId":50805,"journal":{"name":"American Journal of Preventive Medicine","volume":"69 2","pages":"Article 107926"},"PeriodicalIF":4.5,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144723291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cabergoline Impairs Neural Network Efficiency: EEG-Based Evidence from Machine Learning Analysis and Preventive Implications for Cognitive Decline","authors":"Puyu Zhou , Junjie Wang , Jiazheng Duan","doi":"10.1016/j.amepre.2025.107885","DOIUrl":"10.1016/j.amepre.2025.107885","url":null,"abstract":"<div><h3>Objective</h3><div>This study investigates the effects of the D2 receptor agonist cabergoline on neural activity associated with Visual-Spatial Working Memory (VSWM), aiming to enhance understanding of pharmacological modulation of cognitive functions and explore its potential implications for preventive medicine, particularly in cognitive health preservation.</div></div><div><h3>Subjects and Methods</h3><div>This study uses the OpenNeuro public dataset, which includes data from 27 healthy adults who received either cabergoline or a placebo. Electroencephalography (EEG) data were analyzed to extract key neural network features, such as Power Spectral Density (PSD), Phase Locking Value (PLV), and small-world network properties. Machine learning techniques, including Recursive Feature Elimination (RFE) and random forest classifiers, were applied to assess the impact of cabergoline on neural efficiency and synchronization.</div></div><div><h3>Results</h3><div>The results indicate significant changes in neural signal synchronicity and brain network efficiency following cabergoline administration, with the PLV matrix showing the most notable effect. The drug appears to disrupt neural synchronization, potentially impairing VSWM capacity. The random forest model achieved 99% test accuracy, indicating robust classification of the drug's effects on cognitive performance.</div></div><div><h3>Conclusions</h3><div>This study provides new insights into the neural mechanisms of D2 receptor agonists like cabergoline, revealing potential implications for cognitive health. These findings contribute to the development of cognitive health management strategies, offering valuable guidance for early detection and intervention in cognitive decline, particularly in aging or neurodegenerative conditions, with broader applications in preventive medicine.</div></div>","PeriodicalId":50805,"journal":{"name":"American Journal of Preventive Medicine","volume":"69 2","pages":"Article 107885"},"PeriodicalIF":4.5,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144723312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kian Deng Tye , Xiaoyi Liu , Chan Huang , Chen Li , Chaoli Wu , Junlue Lin , Yongjin Yu , Xinzi Lin
{"title":"The Effect of Probiotic Supplementation During Pregnancy on Gut Microbiome Colonization of Newborns","authors":"Kian Deng Tye , Xiaoyi Liu , Chan Huang , Chen Li , Chaoli Wu , Junlue Lin , Yongjin Yu , Xinzi Lin","doi":"10.1016/j.amepre.2025.107888","DOIUrl":"10.1016/j.amepre.2025.107888","url":null,"abstract":"<div><h3>Introduction</h3><div>Probiotics are live microorganisms that may enhance or restore gut microbiota. They are often recommended during pregnancy and infancy for potential benefits, but evidence is inconclusive. This study aimed to investigate probiotic supplementation’s effects on maternal and infant gut and milk microbiota and its link to nutrient intake during pregnancy.</div></div><div><h3>Method</h3><div>We recruited 23 pregnant women and their infants, assigning them to probiotic or control groups. Probiotic effects were evaluated through fecal and milk microbiota analysis via 16S rRNA gene sequencing. Nutrient intake data were collected to assess differences linked to probiotics. Key microbiota diversity and richness were analyzed using linear discriminant analysis effect size (LEfSe) and weighted gene co-expression network analysis (WGCNA) to explore associations with diet and sample characteristics. Predictive microbial pathway characteristics were identified using time series analysis, random forest algorithms, and logistic regression models.</div></div><div><h3>Results</h3><div>The groups had no significant differences in nutrient intake, and gut and milk microbiota richness and diversity remained unchanged. LEfSe identified key genera differing between groups, likely due to probiotic intake. WGCNA found microbiota modules linked to dietary intake and sampling conditions. Analysis also revealed predictive genus clusters affected by probiotics, showing substantial predictive capability.</div></div><div><h3>Conclusion</h3><div>This study suggests a potential link between probiotic supplementation and changes in maternal and infant microbiota, offering insights into health resilience during pregnancy. These results highlight the complex interactions between probiotics, diet, and microbiota, suggesting that probiotics may support maternal and infant health.</div></div>","PeriodicalId":50805,"journal":{"name":"American Journal of Preventive Medicine","volume":"69 2","pages":"Article 107888"},"PeriodicalIF":4.5,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144723315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Research Progress on Occupational Stress of Weightlifting Coaches","authors":"Daoye Lu, Xiangui Bu","doi":"10.1016/j.amepre.2025.107915","DOIUrl":"10.1016/j.amepre.2025.107915","url":null,"abstract":"<div><h3>Introduction</h3><div>This study aims to comprehensively review current research on occupational stress experienced by weightlifting coaches, emphasizing the primary sources of stress, its impacts, coping mechanisms, and effective intervention strategies. Recognizing occupational stress is crucial for enhancing coaches’ mental health, professional efficacy, and overall athlete performance.</div></div><div><h3>Method</h3><div>A systematic literature review was conducted, covering qualitative and quantitative studies published over the past two decades. Electronic databases including PubMed, PsycINFO, and SPORTDiscus were systematically searched using keywords such as “weightlifting coaches,” “occupational stress,” “job burnout,” and “coaching pressure.” Relevant literature was selected, analyzed, and synthesized to provide a comprehensive understanding of the topic.</div></div><div><h3>Results</h3><div>Key findings of this review include: (1) primary stressors such as performance pressures, administrative duties, interpersonal conflicts, and difficulty maintaining work-life balance significantly impact weightlifting coaches; (2) chronic stress often leads to burnout, manifesting as emotional exhaustion, depersonalization, and reduced professional satisfaction, consequently impairing coaching effectiveness and negatively influencing athlete performance; (3) coaches frequently employ coping strategies including seeking social support, physical activity, and mindfulness practices, though individual outcomes vary widely; and (4) organizational interventions, notably professional development, workload management, counseling services, and fostering supportive work environments, have been consistently effective in reducing occupational stress.</div></div><div><h3>Discussion</h3><div>Occupational stress remains a critical issue for weightlifting coaches, necessitating integrated individual and organizational approaches. Future studies should explore tailored, evidence-based interventions, quantify their effectiveness, and examine the long-term implications of stress to sustainably improve coaches’ health, job satisfaction, and athlete success.</div></div>","PeriodicalId":50805,"journal":{"name":"American Journal of Preventive Medicine","volume":"69 2","pages":"Article 107915"},"PeriodicalIF":4.5,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144723356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}