American Journal of Preventive Medicine最新文献

{"title":"AI-Assisted Painting Analysis for Early Alzheimer’s Screening: A Multicenter Validation Study","authors":"Jingjing Wang","doi":"10.1016/j.amepre.2025.107921","DOIUrl":"10.1016/j.amepre.2025.107921","url":null,"abstract":"<div><h3>Introduction</h3><div>To develop an AI-driven tool for early Alzheimer’s disease (AD) screening using digital painting analysis, aiming to address population health challenges through non-invasive, cost-effective risk stratification.</div></div><div><h3>Method</h3><div>A multicenter cohort of 320 participants (160 AD patients, 160 age-matched controls) completed neuropsychological assessments and digital freehand drawings on a digitizing tablet. A CNN-based AI model extracted 384 features from stroke patterns, color distribution, and temporal dynamics. Key discriminative features (reduced color diversity, fragmented lines) were validated against cognitive decline (MMSE scores) and longitudinal progression (n=80). Ethical compliance ensured anonymized data processing under GDPR/HIPAA.</div></div><div><h3>Results</h3><div>The AI model achieved 92% sensitivity and 85% specificity in identifying early-stage AD, outperforming traditional cognitive tests (e.g., MMSE). Reduced color diversity (AUC=0.87) and repetitive geometric motifs (p=0.003) emerged as robust predictors. Longitudinal data revealed progressive feature deterioration (r=0.71) linked to cognitive decline.</div></div><div><h3>Discussion</h3><div>This AI tool enables population-wide AD risk screening, aligning with preventive healthcare goals by facilitating early intervention. Its scalability and non-invasive nature support integration into routine health assessments, reducing the burden of undetected AD and advancing public health strategies for aging populations.</div></div>","PeriodicalId":50805,"journal":{"name":"American Journal of Preventive Medicine","volume":"69 2","pages":"Article 107921"},"PeriodicalIF":4.5,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144723423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Impact of Virtual Reality Technology on Delirium, Sleep Quality, and Negative Emotions in Critically Ill Patients in the ICU","authors":"Liang Guo,&nbsp;Jingqi Zhang","doi":"10.1016/j.amepre.2025.107907","DOIUrl":"10.1016/j.amepre.2025.107907","url":null,"abstract":"<div><h3>Introduction</h3><div>To investigate the effects of virtual reality technology on delirium, sleep quality, and negative emotions in critically ill patients in the intensive care unit (ICU), with the aim of assessing its potential application in clinical nursing</div></div><div><h3>Method</h3><div>A cohort of critically ill patients in the ICU underwent virtual reality interventions, which included immersive virtual environment experiences designed to alleviate patient anxiety and discomfort. Pre- and post-intervention assessments were conducted using the delirium assessment scale, the Pittsburgh Sleep Quality Index (PSQI), and a negative emotion scale to compare changes and quantify the effects of virtual reality technology.</div></div><div><h3>Results</h3><div>Following the intervention, the incidence of delirium significantly decreased, with patients’ scores on the delirium assessment scale showing a notable decline compared to pre-intervention levels (P&lt;0.05), indicating a positive effect of virtual reality interventions in the prevention of delirium. In terms of sleep quality, patients demonstrated significant improvements in PSQI scores post-intervention (P&lt;0.01), reflecting the effectiveness of virtual reality technology in enhancing sleep quality. Additionally, scores on the negative emotion scale also significantly decreased (P&lt;0.01), indicating a substantial alleviation of patients’ anxiety and depressive symptoms.</div></div><div><h3>Discussion</h3><div>Virtual reality technology exhibits significant intervention effects in the nursing care of critically ill patients in the ICU, effectively reducing the incidence of delirium, improving sleep quality, and mitigating negative emotions. This technology offers an innovative psychological intervention approach for critically ill patients, demonstrating promising clinical application prospects that warrant further promotion and research in future nursing practice.</div></div>","PeriodicalId":50805,"journal":{"name":"American Journal of Preventive Medicine","volume":"69 2","pages":"Article 107907"},"PeriodicalIF":4.5,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144723487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integrating Health Prevention, Health Education and Healthy Development: Innovative approaches to Building a Health System","authors":"Juan Yu","doi":"10.1016/j.amepre.2025.107880","DOIUrl":"10.1016/j.amepre.2025.107880","url":null,"abstract":"<div><h3>Background</h3><div>Aiming to explore the importance of integrating health prevention, health education and healthy development, this study analyzes four major positions: healthy living, health literacy, health maintenance and health monitoring through a literature review, and proposes strategies for building a health system. The study pointed out that integrating approaches should be centered on the “question” to enhance the health prevention of the research and incorporate it into the evaluation criteria of integrating approaches. This study helps researchers to shift from spontaneity to integrating, to conduct more insightful and relevant integrating approaches, and to promote the diversification of health improvement.</div></div><div><h3>Subjects and approaches</h3><div>The integrating approaches of post-positivist aapproach, hermeneutic aapproach, phenomenological aapproach and social constructionist aapproach, grounded theory and narrative research are adopted. Through in-depth interviews with interviewees' health education and health development, who were asked about their specific feelings and coping styles of health early warning and public health. Finally, the health ssystem are builded and integrating approaches are innovated.</div></div><div><h3>Results</h3><div>During the development of modern health science, scientific health takes the scientific nature of approaches and tools as a criterion. In order to improve the validity of research in social practice and guide the researchers from spontaneity to problem-solving in their choice of disease prevention.</div></div><div><h3>Conclusions</h3><div>The integrating approaches embody a progression from theoretical derivation and health prevention toward public health. The multiple approaches which combine health equity and health maintenance, and break the limitations of traditional integrating, to open up a new path for personalized health intervention.</div></div>","PeriodicalId":50805,"journal":{"name":"American Journal of Preventive Medicine","volume":"69 2","pages":"Article 107880"},"PeriodicalIF":4.5,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144723411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Healthy Living and Design Research Hot Spots and Trend Analysis","authors":"Yajun Zhao","doi":"10.1016/j.amepre.2025.107898","DOIUrl":"10.1016/j.amepre.2025.107898","url":null,"abstract":"<div><h3>Introduction</h3><div>This study systematically examines research trends in the intersection of healthy living and design from 2014 to 2024, focusing on key themes and developments.</div></div><div><h3>Method</h3><div>A detailed analysis was conducted on the research trends at the intersection of healthy living and design over a decade. Using the WOS database, relevant literature was selected and visualized using CiteSpace. Research methods include keyword co-occurrence to identify core themes of healthy living, central analysis to assess the impact of specific studies, analysis of international research networks to understand global research partnerships, and checking highly cited literature to determine the greatest contribution to healthy living and design.</div></div><div><h3>Results</h3><div>The analysis shows that \"sports activities,\" \"design,\" and \"health\" are core themes in the fields of healthy living and design, widely discussed in both academia and practice and widely recognized for their importance. Furthermore, as people's demands for quality of life rise, emerging topics such as \"green spaces\" and \"urban environments\" are gaining increasing attention and importance, reflecting a pursuit of sustainable and environmentally friendly lifestyles. In the field of international research, the United States, China, and the United Kingdom have made particularly significant contributions to healthy living and design, showcasing their research capabilities and the increasing frequency and activity of international cooperation in this area.</div></div><div><h3>Discussion</h3><div>The study highlights the evolving focus within healthy living and design research, reflecting a growing interest in environmental and urban factors. The identified key countries and their collaborative efforts underscore the global nature of this research area.</div></div>","PeriodicalId":50805,"journal":{"name":"American Journal of Preventive Medicine","volume":"69 2","pages":"Article 107898"},"PeriodicalIF":4.5,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144723420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Comparative Study on the Transformation Pathways of Public Health Systems in China, the United States, and South Korea from an International Perspective","authors":"Wei Ding ,&nbsp;Huiwen Guo ,&nbsp;Tao Wang ,&nbsp;Joohan Ryoo ,&nbsp;Hailin Zhu ,&nbsp;Chunyan Ji","doi":"10.1016/j.amepre.2025.107930","DOIUrl":"10.1016/j.amepre.2025.107930","url":null,"abstract":"<div><h3>Objective</h3><div>This study aims to systematically analyze the pathway differences in the transformation of public health systems from crisis response-oriented to health governance-oriented models in China, the United States, and South Korea through an international comparative perspective. It focuses on revealing the impact mechanism of institutional adaptability on public health governance effectiveness, providing theoretical references and practical insights for the global transformation of public health systems.</div></div><div><h3>Subjects and Methods</h3><div>(1) Institutional Design: China’s restructuring of the \"central-local\" governance framework, the U.S.’s community health governance innovation under federalism, and South Korea’s revision of the National Health Insurance Act; (2) Practical Pathways: China’s integration of the Patriotic Health Campaign with grassroots service upgrades, the U.S.’s risk prediction models developed through collaboration between the Centers for Disease Control and Prevention (CDC) and commercial insurers, and South Korea’s digital upgrading of the \"Epidemic Control Tower\"; (3) Common Logic: Extraction of institutional adaptability characteristics in the transformations of all three countries through policy text analysis and governance effectiveness evaluation.</div></div><div><h3>Results</h3><div>(1) China integrates vertical management with regularized health promotion to upgrade grassroots public health capabilities, transitioning from \"passive epidemic response\" to \"proactive health management\"; (2) the U.S. optimizes resource allocation through market-driven mechanisms and community governance innovation, leveraging social capital to bridge healthcare gaps; (3) South Korea establishes a legislation-driven \"digital-prevention\" ecosystem, integrating epidemic data with chronic disease management to achieve lifelong health coverage.</div></div><div><h3>Conclusions</h3><div>Institutional adaptability—enhancing administrative efficiency, activating market mechanisms, and breakthroughs in technological innovation—has effectively resolved challenges in public health systems.</div></div>","PeriodicalId":50805,"journal":{"name":"American Journal of Preventive Medicine","volume":"69 2","pages":"Article 107930"},"PeriodicalIF":4.5,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144723295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integrating Preventive Medicine and Sports Rehabilitation: A Network Meta-analysis of Optimal Strategies for Chronic Ankle Instability Management in Active Populations","authors":"Ping Lu ,&nbsp;Feilong Li ,&nbsp;Liangqiu Lu ,&nbsp;Fangbo Li","doi":"10.1016/j.amepre.2025.107876","DOIUrl":"10.1016/j.amepre.2025.107876","url":null,"abstract":"<div><h3>Objective</h3><div>Chronic ankle instability (CAI) poses a major public health challenge, increasing the risk of recurrent injury and long-term musculoskeletal degeneration. This study evaluates rehabilitation interventions for CAI patients from a preventive medicine perspective, aiming to identify the best strategies for rehabilitation and prevention of recurrent instability and reduce the healthcare burden associated with CAI-related disability.</div></div><div><h3>Methods</h3><div>This study systematically analyzed eligible randomized controlled trials from multiple databases including Web of Science, focusing on interventions with the potential to prevent CAI recurrence. The methodological quality of the included studies was assessed using the Cochrane Risk of Bias Tool. Network meta-analysis was performed using STATA 15.1 software.</div></div><div><h3>Results</h3><div>Several interventions, including Graston instrument-assisted soft tissue mobilization combined with dynamic balance training and comprehensive strength and balance training, showed significant improvements in SEBT scores in patients with CAI. Instability devices and balance board training showed good results in improving Foot and Ankle Ability Measure (FAAM) scores, directly supporting preventive rehabilitation by restoring functional ability.</div></div><div><h3>Conclusion</h3><div>Among the 15 interventions studied, Graston instrument-assisted soft tissue mobilization combined with dynamic balance training was identified as the best intervention to improve SEBT scores in patients with CAI, providing a theoretical basis for healthcare systems to develop appropriate prevention programs. However, the strength of these conclusions should be interpreted with caution due to limitations and potential biases of the primary studies. Further high-quality randomized controlled trials are needed to confirm these findings and develop evidence-based recommendations for the rehabilitation and prevention of CAI.</div></div>","PeriodicalId":50805,"journal":{"name":"American Journal of Preventive Medicine","volume":"69 2","pages":"Article 107876"},"PeriodicalIF":4.5,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144723174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prognostic Value of Combined Determination of NLR, PLR, CRP and IL-6 in Peripheral Blood for Adamyumab Treatment in Patients with Ankylosing Spondylitis","authors":"Meiqun Zhou","doi":"10.1016/j.amepre.2025.107913","DOIUrl":"10.1016/j.amepre.2025.107913","url":null,"abstract":"<div><h3>Introduction</h3><div>To evaluate the predictive value of combined determination of peripheral neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR), C-reactive protein (CRP) and interleukin-6 (IL-6) in the treatment of adamylizumab in patients with ankylosing spondylitis (AS).</div></div><div><h3>Method</h3><div>From January 2020 to May 2024, 60 patients with AS in our hospital were selected and treated with adalimumab for 12 weeks. The changes of NLR, PLR, CRP, IL-6 levels before and after treatment were compared, and the improvement of the disease was assessed by BASMI spinal activity, and the patients were divided into ineffective group (BASMI&gt;4 points) and effective group (BASMI≤4 points). The correlation between Spearman and BASMI was analyzed, and the predictive value was analyzed by ROC curve.</div></div><div><h3>Results</h3><div>After treatment, the scores of NLR, PLR, CRP, IL-6 and BASMI were decreased compared with those before treatment (P&lt;0.05). The levels of NLR, PLR, CRP and IL-6 were positively correlated with BASMI (P&lt;0.05). Before treatment, the indexes in the ineffective group were higher than those in the effective group (P&lt;0.05). The combined prediction AUC is 0.664.</div></div><div><h3>Discussion</h3><div>The combined determination of NLR, PLR, CRP and IL-6 in peripheral blood can predict the therapeutic effect of adalimumab in patients with AS.</div></div>","PeriodicalId":50805,"journal":{"name":"American Journal of Preventive Medicine","volume":"69 2","pages":"Article 107913"},"PeriodicalIF":4.5,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144723353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic Value of Neutrophil-to-Lymphocyte Ratio for Poor Prognosis of Intravenous Thrombolysis in Acute Cerebral Infarction: A Systematic Review and Meta-Analysis","authors":"Mujia Shi ,&nbsp;Ziqian Wang ,&nbsp;Xinyu Ren ,&nbsp;Rui Liu ,&nbsp;Bonan Hou","doi":"10.1016/j.amepre.2025.107911","DOIUrl":"10.1016/j.amepre.2025.107911","url":null,"abstract":"<div><h3>Introduction</h3><div>The aim of this study was to assess the diagnostic value of neutrophil-to-lymphocyte ratio (NLR) in predicting poor prognosis in cerebral infarction.</div></div><div><h3>Method</h3><div>We searched PubMed, Web of Science, Embase, CNKI, Wanfang database, China Biomedical Literature Database (SinoMed), VIP, and the Cochrane Library to systematically retrieve relevant literature. Diagnostic value was assessed using forest plots, sensitivity, specificity, positive likelihood ratios, negative likelihood ratios and diagnostic odds ratios, and publication bias was assessed using funnel plots.</div></div><div><h3>Results</h3><div>A total of 55 studies with 10,958 cases were included. Meta-analysis showed: Pre-thrombolysis NLR predicted poor prognosis with 0.70 sensitivity and 0.75 specificity. Post-thrombolysis NLR had 0.71 sensitivity and 0.72 specificity. Subgroup analysis showed no heterogeneity in pre-thrombolysis NLR for poor functional outcomes (ADL) and post-thrombolysis NLR for mortality and stroke-associated pneumonia (SAP). Sensitivity analysis confirmed result stability. Deeks’ funnel plot suggested no publication bias (P&lt;0.05).</div></div><div><h3>Discussion</h3><div>NLR has moderate diagnostic value in predicting the prognosis of AIS, and can provide reference for treatment decision-making and rehabilitation management of AIS. However, due to the limitations of the quantity, quality and sample size of the included studies, the above conclusions still need to be confirmed by more large-sample, multi-center prospective studies.</div></div>","PeriodicalId":50805,"journal":{"name":"American Journal of Preventive Medicine","volume":"69 2","pages":"Article 107911"},"PeriodicalIF":4.5,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144723426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Research on the Application of Sports Health Management Platforms in the Precise Analysis and Intervention of Medical Data","authors":"Min Zhang,&nbsp;Qingzhen Zhang","doi":"10.1016/j.amepre.2025.107892","DOIUrl":"10.1016/j.amepre.2025.107892","url":null,"abstract":"<div><h3>Introduction</h3><div>This study aims to investigate the application of exercise health management platforms in the precise analysis and intervention of medical data.</div></div><div><h3>Method</h3><div>Multidimensional health data from diverse populations were collected, including physiological indicators, exercise habits, nutritional intake, and lifestyle information. Utilizing machine learning and statistical analysis methods, feature extraction was conducted to identify key factors associated with health risks, and predictive models were constructed to assess individual health status and potential risks.</div></div><div><h3>Results</h3><div>The exercise health management platform demonstrates significant advantages in data integration and analysis. Through real-time monitoring of users’ health data, the platform is capable of promptly identifying health risks and providing targeted intervention recommendations. Following the use of this platform, users experienced an average reduction of 3.5% in body mass index (BMI), a 12% improvement in cardiopulmonary function test scores, and a 15% enhancement in mental health ratings. In terms of chronic disease management, diabetic patients exhibited notable improvements in blood glucose control, with an average decrease of 1.2 percentage points in HbA1c levels, while the blood pressure control rate among hypertensive patients increased by 20%. Additionally, the platform developed personalized exercise plans and nutritional guidance tailored to users of different age groups and health conditions.</div></div><div><h3>Discussion</h3><div>The exercise health management platform facilitates real-time monitoring and assessment of individual health status through precise analysis. It shows promising applications in chronic disease management, health monitoring for the elderly, and interventions for special populations, effectively reducing healthcare costs and improving the accessibility and efficiency of health services.</div></div>","PeriodicalId":50805,"journal":{"name":"American Journal of Preventive Medicine","volume":"69 2","pages":"Article 107892"},"PeriodicalIF":4.5,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144723235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Physical Activity on the Gut Microbiota in Late Pregnancy","authors":"Kian Deng Tye ,&nbsp;XiaoYi Liu ,&nbsp;QiLian Long ,&nbsp;YongChuang Lin ,&nbsp;LuLu Wu ,&nbsp;XiaoMin Xiao ,&nbsp;Ping Yang","doi":"10.1016/j.amepre.2025.107896","DOIUrl":"10.1016/j.amepre.2025.107896","url":null,"abstract":"<div><h3>Introduction</h3><div>This investigation examined how moderate physical activity in late pregnancy affects gut microbiota using next-generation sequencing techniques, providing evidence of maternal benefits health.</div></div><div><h3>Method</h3><div>A prospective cohort study was conducted involving 23 pregnant women at 32 weeks of gestation. Fecal samples were subjected to 16S rDNA sequencing, and daily physical activity levels were recorded. Participants were stratified into two groups: T1 (≥30 minutes/day, consisting of 18 women) and T2 (&lt;30 minutes/day, consisting of 5 women). Bioinformatics methods were employed to analyze gut microbiota composition, diversity, and its correlation with physical activity levels.</div></div><div><h3>Results</h3><div>The dominant phyla identified in both groups included Firmicutes, Bacteroidetes, Actinomycetes, and Proteobacteria. Alpha diversity and principal coordinate analysis indicated no significant differences in microbial diversity. However, LEfSe analysis identified an enrichment of Christensenellaceae and Prevotella stercorea in group T2. The T1 group demonstrated a more complex and stable gut microbial network, illustrated by positive correlations among the microbes. Spearman analysis revealed significant associations between activity levels and specific gut microbes: sedentary behavior was correlated with Romboutsia (P = 0.033, R = -0.445) and Senegalimassilia (P = 0.043, R = -0.443); light-intensity activity with Phascolarctobacterium (P = 0.015, R = -0.500); and moderate-intensity activity with Parasutterella (P = 0.040, R = 0.432).</div></div><div><h3>Discussion</h3><div>Moderate physical activity during late pregnancy enhances the stability and complexity of gut microbiota, providing benefits for maternal health. Next-generation sequencing offers valuable insights into the relationship between exercise and gut microbiota in pregnant women.</div></div>","PeriodicalId":50805,"journal":{"name":"American Journal of Preventive Medicine","volume":"69 2","pages":"Article 107896"},"PeriodicalIF":4.5,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144723175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}