Ethan Chervonski MD, MPH , Elan Pelegri MS , Franzenith De La Calle MS, RD , Soumik Mandal PhD , Claire A. Graves MD , Doreen Colella RN, MSN , Arielle Elmaleh-Sachs MD, MS , Jacalyn Nay RN, MHL, CCM , Isaac Dapkins MD , Antoinette Schoenthaler EdD, MA
{"title":"Cardiovascular Health Markers With Remote Team-Based Hypertension Management in a Safety-Net Population","authors":"Ethan Chervonski MD, MPH , Elan Pelegri MS , Franzenith De La Calle MS, RD , Soumik Mandal PhD , Claire A. Graves MD , Doreen Colella RN, MSN , Arielle Elmaleh-Sachs MD, MS , Jacalyn Nay RN, MHL, CCM , Isaac Dapkins MD , Antoinette Schoenthaler EdD, MA","doi":"10.1016/j.amepre.2025.108031","DOIUrl":null,"url":null,"abstract":"<div><h3>Introduction</h3><div>The impact of remote patient monitoring for hypertension on cardiovascular health remains ill defined. This study characterized the association between a remote patient monitoring, team-based hypertension intervention and cardiovascular health markers.</div></div><div><h3>Methods</h3><div>This retrospective, single-arm cohort study included patients with uncontrolled hypertension enrolled from February 2022 to July 2024 in the ALTA trial (clinicaltrials.gov NCT03713515) at 5 safety-net practices. The ALTA intervention involves remote patient monitoring supported by a virtual clinic managed by a nurse practitioner, a registered nurse, and a community health worker. Demographics, ALTA utilization, and cardiovascular health markers (blood pressure, lipids, glycemic indicators, BMI, and smoking history) at baseline and 12 months were collected. The 5 cardiovascular health markers were scored (0=poor, 1=intermediate, 2=ideal) and summed into a cardiovascular health score. The primary endpoint was a change in the 12-month cardiovascular health score among patients with a baseline score of ≤7. Secondary endpoints included changes in individual non-blood pressure markers among patients with baseline derangements.</div></div><div><h3>Results</h3><div>Among the 568 included patients (mean age: 56 years), most were female, non-Hispanic Black, and English-speaking individuals. Nurse practitioner visits were more common among females (<em>p</em>=0.04), with no other demographics predicting ALTA utilization. The cardiovascular health score improved from 4.5 to 5.2 (<em>n</em>=196, <em>p</em><0.001), independent of ALTA utilization. Total cholesterol (<em>n</em>=86, <em>p</em><0.001), low-density lipoprotein (<em>n</em>=128, <em>p</em><0.001), and triglyceride levels (<em>n</em>=51, <em>p</em>=0.004) also improved. Hemoglobin A<sub>1c</sub> (<em>n</em>=195) dropped among patients with ≥1 nurse practitioner visit (<em>p</em>=0.02). Fasting glucose (<em>n</em>=135) and BMI (<em>n</em>=289) decreased in the highest tertile of nurse practitioner visits (<em>p</em>=0.03) and remote patient monitoring (<em>p</em>=0.02), respectively. Finally, 4 of 27 patients quit smoking.</div></div><div><h3>Conclusions</h3><div>Remote patient monitoring with team-based support was associated with cardiovascular health improvements. However, benefits may depend on the intervention’s utilization.</div></div>","PeriodicalId":50805,"journal":{"name":"American Journal of Preventive Medicine","volume":"69 5","pages":"Article 108031"},"PeriodicalIF":4.5000,"publicationDate":"2025-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"American Journal of Preventive Medicine","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0749379725005082","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
引用次数: 0
Abstract
Introduction
The impact of remote patient monitoring for hypertension on cardiovascular health remains ill defined. This study characterized the association between a remote patient monitoring, team-based hypertension intervention and cardiovascular health markers.
Methods
This retrospective, single-arm cohort study included patients with uncontrolled hypertension enrolled from February 2022 to July 2024 in the ALTA trial (clinicaltrials.gov NCT03713515) at 5 safety-net practices. The ALTA intervention involves remote patient monitoring supported by a virtual clinic managed by a nurse practitioner, a registered nurse, and a community health worker. Demographics, ALTA utilization, and cardiovascular health markers (blood pressure, lipids, glycemic indicators, BMI, and smoking history) at baseline and 12 months were collected. The 5 cardiovascular health markers were scored (0=poor, 1=intermediate, 2=ideal) and summed into a cardiovascular health score. The primary endpoint was a change in the 12-month cardiovascular health score among patients with a baseline score of ≤7. Secondary endpoints included changes in individual non-blood pressure markers among patients with baseline derangements.
Results
Among the 568 included patients (mean age: 56 years), most were female, non-Hispanic Black, and English-speaking individuals. Nurse practitioner visits were more common among females (p=0.04), with no other demographics predicting ALTA utilization. The cardiovascular health score improved from 4.5 to 5.2 (n=196, p<0.001), independent of ALTA utilization. Total cholesterol (n=86, p<0.001), low-density lipoprotein (n=128, p<0.001), and triglyceride levels (n=51, p=0.004) also improved. Hemoglobin A1c (n=195) dropped among patients with ≥1 nurse practitioner visit (p=0.02). Fasting glucose (n=135) and BMI (n=289) decreased in the highest tertile of nurse practitioner visits (p=0.03) and remote patient monitoring (p=0.02), respectively. Finally, 4 of 27 patients quit smoking.
Conclusions
Remote patient monitoring with team-based support was associated with cardiovascular health improvements. However, benefits may depend on the intervention’s utilization.
期刊介绍:
The American Journal of Preventive Medicine is the official journal of the American College of Preventive Medicine and the Association for Prevention Teaching and Research. It publishes articles in the areas of prevention research, teaching, practice and policy. Original research is published on interventions aimed at the prevention of chronic and acute disease and the promotion of individual and community health.
Of particular emphasis are papers that address the primary and secondary prevention of important clinical, behavioral and public health issues such as injury and violence, infectious disease, women''s health, smoking, sedentary behaviors and physical activity, nutrition, diabetes, obesity, and substance use disorders. Papers also address educational initiatives aimed at improving the ability of health professionals to provide effective clinical prevention and public health services. Papers on health services research pertinent to prevention and public health are also published. The journal also publishes official policy statements from the two co-sponsoring organizations, review articles, media reviews, and editorials. Finally, the journal periodically publishes supplements and special theme issues devoted to areas of current interest to the prevention community.