Amy M. Cohn PhD , Summer Frank-Pearce PhD , Hoda Elmasry MPH , Rachel L. Denlinger-Apte PhD, MPH , Ratnapriya Ghosh MHP , Eric C. Donny PhD , Andrea C. Villanti PhDMPH , Dorothy K. Hatsukami PhD , Delaney Dunn PhD , Riley Wyatt MS , Taylor G. Niznik BS , Michael A. Smith MS, MPH , Alexa Brown BS , Clark Gilford JR, MPH , Sarah E. Joslin BA , Madelyne Wilson BA , Sarah J. Ehlke PhD , Rachel N. Cassidy PhD
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引用次数: 0
Abstract
Introduction
The U.S. Food and Drug Administration proposed rulemaking to reduce cigarette nicotine content and ban menthol in cigarettes. Menthol is popular among young adults who smoke, although it is unclear how this group would respond if both policies were implemented.
Methods
A total of 112 young adults who smoke menthol cigarettes completed 3 visits that varied by cigarette smoked (2021–2024): usual brand menthol, menthol very-low-nicotine cigarette (0.3 mg nicotine/g tobacco), and nonmenthol very-low-nicotine cigarette. Very-low-nicotine cigarette flavor order was counterbalanced. Subjective response and smoking topography were assessed at each session as well as pre–post smoking measurements of expired carbon monoxide, cigarette weight, cardiovascular effects, nicotine withdrawal, and craving. Repeated-measures ANOVAs were used to examine differences in the outcomes across cigarette type.
Results
Total smoking duration, interpuff interval, and puff count were higher for usual brand than for both very-low-nicotine cigarette smoking. Interpuff interval was higher in menthol very-low-nicotine cigarette smoking than nonmenthol. Usual brand was more appealing than both very-low-nicotine cigarettes and led to greater increases in carbon monoxide and cardiovascular effects and decreased postsmoking cigarette weight and craving compared with both very-low-nicotine cigarettes. Menthol very-low-nicotine cigarettes produced more positive subjective responses, higher carbon monoxide, and lower postsmoking cigarette weight and craving than nonmenthol.
Conclusions
Participants preferred menthol over nonmenthol very-low-nicotine cigarettes, although very-low-nicotine cigarettes were less appealing than usual brand, overall. Despite similar topography across very-low-nicotine cigarette flavors, toxicant exposure and craving were greater and lower, respectively, after menthol than after nonmenthol very-low-nicotine cigarette smoking. Findings support the U.S. Food and Drug Administration’s proposals to ban menthol cigarettes and institute market-wide reductions in cigarette nicotine content.
期刊介绍:
The American Journal of Preventive Medicine is the official journal of the American College of Preventive Medicine and the Association for Prevention Teaching and Research. It publishes articles in the areas of prevention research, teaching, practice and policy. Original research is published on interventions aimed at the prevention of chronic and acute disease and the promotion of individual and community health.
Of particular emphasis are papers that address the primary and secondary prevention of important clinical, behavioral and public health issues such as injury and violence, infectious disease, women''s health, smoking, sedentary behaviors and physical activity, nutrition, diabetes, obesity, and substance use disorders. Papers also address educational initiatives aimed at improving the ability of health professionals to provide effective clinical prevention and public health services. Papers on health services research pertinent to prevention and public health are also published. The journal also publishes official policy statements from the two co-sponsoring organizations, review articles, media reviews, and editorials. Finally, the journal periodically publishes supplements and special theme issues devoted to areas of current interest to the prevention community.