Annual Review of Clinical Psychology最新文献_第10页

Stress and Psychiatric Disorders: The Role of Mitochondria. 应激与精神疾病:线粒体的作用。

IF 18.4 1区心理学

Annual Review of Clinical Psychology Pub Date : 2020-05-07 Epub Date: 2020-02-24 DOI: 10.1146/annurev-clinpsy-082719-104030

Teresa E Daniels, Elizabeth M Olsen, Audrey R Tyrka

{"title":"Stress and Psychiatric Disorders: The Role of Mitochondria.","authors":"Teresa E Daniels, Elizabeth M Olsen, Audrey R Tyrka","doi":"10.1146/annurev-clinpsy-082719-104030","DOIUrl":"https://doi.org/10.1146/annurev-clinpsy-082719-104030","url":null,"abstract":"In seeking to understand mental health and disease, it is fundamental to identify the biological substrates that draw together the experiences and physiological processes that underlie observed psychological changes. Mitochondria are subcellular organelles best known for their central role in energetics, producing adenosine triphosphate to power most cellular processes. Converging lines of evidence indicate that mitochondria play a key role in the biological embedding of adversity. Preclinical research documents the effects of stress exposure on mitochondrial structure and function, and recent human research suggests alterations constituting recalibrations, both adaptive and nonadaptive. Current research suggests dynamic relationships among stress exposure, neuroendocrine signaling, inflammation, and mitochondrial function. These complex relationships are implicated in disease risk, and their elucidation may inform prevention and treatment of stress- and trauma-related disorders. We review and evaluate the evidence for mitochondrial dysfunction as a consequence of stress exposure and as a contributing factor to psychiatric disease.","PeriodicalId":50755,"journal":{"name":"Annual Review of Clinical Psychology","volume":null,"pages":null},"PeriodicalIF":18.4,"publicationDate":"2020-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1146/annurev-clinpsy-082719-104030","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37672399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 46

Risk and Resilience in Minority Youth Populations. 少数民族青年人口的风险和复原力。

IF 18.4 1区心理学

Annual Review of Clinical Psychology Pub Date : 2020-05-07 DOI: 10.1146/annurev-clinpsy-071119-115839

Amy K Marks, G Alice Woolverton, Cynthia García Coll

引用次数: 25

Conceptualization, History, and Future of the Paraphilias. 释义、历史和未来。

IF 18.4 1区心理学

Annual Review of Clinical Psychology Pub Date : 2020-05-07 Epub Date: 2020-02-05 DOI: 10.1146/annurev-clinpsy-050718-095548

Charles Moser, Peggy J Kleinplatz

引用次数: 13

Epigenetics, Development, and Psychopathology. 表观遗传学、发育和精神病理学。

IF 18.4 1区心理学

Annual Review of Clinical Psychology Pub Date : 2020-05-07 Epub Date: 2020-02-21 DOI: 10.1146/annurev-clinpsy-050718-095530

Kieran J O'Donnell, Michael J Meaney

引用次数: 35

Social Safety Theory: A Biologically Based Evolutionary Perspective on Life Stress, Health, and Behavior. 社会安全理论：从生物学的进化角度看生活压力、健康和行为。

IF 18.4 1区心理学

Annual Review of Clinical Psychology Pub Date : 2020-05-07 Epub Date: 2020-03-06 DOI: 10.1146/annurev-clinpsy-032816-045159

George M Slavich

{"title":"Social Safety Theory: A Biologically Based Evolutionary Perspective on Life Stress, Health, and Behavior.","authors":"George M Slavich","doi":"10.1146/annurev-clinpsy-032816-045159","DOIUrl":"10.1146/annurev-clinpsy-032816-045159","url":null,"abstract":"Social Safety Theory hypothesizes that developing and maintaining friendly social bonds is a fundamental organizing principle of human behavior and that threats to social safety are a critical feature of psychological stressors that increase risk for disease. Central to this formulation is the fact that the human brain and immune system are principally designed to keep the body biologically safe, which they do by continually monitoring and responding to social, physical, and microbial threats in the environment. Because situations involving social conflict, isolation, devaluation, rejection, and exclusion historically increased risk for physical injury and infection, anticipatory neural-immune reactivity to social threat was likely highly conserved. This neurocognitive and immunologic ability for humans to symbolically represent and respond to potentially dangerous social situations is ultimately critical for survival. When sustained, however, this multilevel biological threat response can increase individuals' risk for viral infections and several inflammation-related disease conditions that dominate present-day morbidity and mortality.","PeriodicalId":50755,"journal":{"name":"Annual Review of Clinical Psychology","volume":null,"pages":null},"PeriodicalIF":18.4,"publicationDate":"2020-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7213777/pdf/nihms-1578206.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37711751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Personalized Models of Psychopathology. 精神病理学的个性化模型。

IF 18.4 1区心理学

Annual Review of Clinical Psychology Pub Date : 2019-09-26 DOI: 10.31234/osf.io/6hqzj

A. Wright, William C. Woods

{"title":"Personalized Models of Psychopathology.","authors":"A. Wright, William C. Woods","doi":"10.31234/osf.io/6hqzj","DOIUrl":"https://doi.org/10.31234/osf.io/6hqzj","url":null,"abstract":"The personalized approach to psychopathology conceptualizes mental disorder as a complex system of contextualized dynamic processes that is nontrivially specific to each individual, and it seeks to develop formal idiographic statistical models to represent these individual processes. Although the personalized approach draws on long-standing influences in clinical psychology, there has been an explosion of research in recent years following the development of intensive longitudinal data capture and statistical techniques that facilitate modeling of the dynamic processes of each individual's pathology. Advances are also making idiographic analyses scalable and generalizable. We review emerging research using the personalized approach in descriptive psychopathology, precision assessment, and treatment selection and tailoring, and we identify future challenges and areas in need of additional research. The personalized approach to psychopathology holds promise to resolve thorny diagnostic issues, generate novel insights, and improve the timing and efficacy of interventions. Expected final online publication date for the Annual Review of Clinical Psychology, Volume 16 is May 7, 2020. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.","PeriodicalId":50755,"journal":{"name":"Annual Review of Clinical Psychology","volume":null,"pages":null},"PeriodicalIF":18.4,"publicationDate":"2019-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47179853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 120

Estrogen, Stress, and Depression: Cognitive and Biological Interactions. 雌激素、压力和抑郁:认知和生物学的相互作用。

IF 18.4 1区心理学

Annual Review of Clinical Psychology Pub Date : 2019-05-07 Epub Date: 2019-02-20 DOI: 10.1146/annurev-clinpsy-050718-095557

Kimberly M Albert, Paul A Newhouse

引用次数: 90

The Role of Common Factors in Psychotherapy Outcomes. 常见因素在心理治疗结果中的作用。

IF 18.4 1区心理学

Annual Review of Clinical Psychology Pub Date : 2019-05-07 Epub Date: 2018-12-14 DOI: 10.1146/annurev-clinpsy-050718-095424

Pim Cuijpers, Mirjam Reijnders, Marcus J H Huibers

{"title":"The Role of Common Factors in Psychotherapy Outcomes.","authors":"Pim Cuijpers, Mirjam Reijnders, Marcus J H Huibers","doi":"10.1146/annurev-clinpsy-050718-095424","DOIUrl":"https://doi.org/10.1146/annurev-clinpsy-050718-095424","url":null,"abstract":"Psychotherapies may work through techniques that are specific to each therapy or through factors that all therapies have in common. Proponents of the common factors model often point to meta-analyses of comparative outcome studies that show all therapies have comparable effects. However, not all meta-analyses support the common factors model; the included studies often have several methodological problems; and there are alternative explanations for finding comparable outcomes. To date, research on the working mechanisms and mediators of therapies has always been correlational, and in order to establish that a mediator is indeed a causal factor in the recovery process of a patient, studies must show a temporal relationship between the mediator and an outcome, a dose-response association, evidence that no third variable causes changes in the mediator and the outcome, supportive experimental research, and have a strong theoretical framework. Currently, no common or specific factor meets these criteria and can be considered an empirically validated working mechanism. Therefore, it is still unknown whether therapies work through common or specific factors, or both.","PeriodicalId":50755,"journal":{"name":"Annual Review of Clinical Psychology","volume":null,"pages":null},"PeriodicalIF":18.4,"publicationDate":"2019-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1146/annurev-clinpsy-050718-095424","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36826234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 339

Abnormal Sleep Spindles, Memory Consolidation, and Schizophrenia. 异常睡眠纺锤波、记忆巩固和精神分裂症。

IF 18.4 1区心理学

Annual Review of Clinical Psychology Pub Date : 2019-05-07 Epub Date: 2019-02-20 DOI: 10.1146/annurev-clinpsy-050718-095754

Dara S Manoach, Robert Stickgold

{"title":"Abnormal Sleep Spindles, Memory Consolidation, and Schizophrenia.","authors":"Dara S Manoach, Robert Stickgold","doi":"10.1146/annurev-clinpsy-050718-095754","DOIUrl":"https://doi.org/10.1146/annurev-clinpsy-050718-095754","url":null,"abstract":"There is overwhelming evidence that sleep is crucial for memory consolidation. Patients with schizophrenia and their unaffected relatives have a specific deficit in sleep spindles, a defining oscillation of non-rapid eye movement (NREM) Stage 2 sleep that, in coordination with other NREM oscillations, mediate memory consolidation. In schizophrenia, the spindle deficit correlates with impaired sleep-dependent memory consolidation, positive symptoms, and abnormal thalamocortical connectivity. These relations point to dysfunction of the thalamic reticular nucleus (TRN), which generates spindles, gates the relay of sensory information to the cortex, and modulates thalamocortical communication. Genetic studies are beginning to provide clues to possible neurodevelopmental origins of TRN-mediated thalamocortical circuit dysfunction and to identify novel targets for treating the related memory deficits and symptoms. By forging empirical links in causal chains from risk genes to thalamocortical circuit dysfunction, spindle deficits, memory impairment, symptoms, and diagnosis, future research can advance our mechanistic understanding, treatment, and prevention of schizophrenia.","PeriodicalId":50755,"journal":{"name":"Annual Review of Clinical Psychology","volume":null,"pages":null},"PeriodicalIF":18.4,"publicationDate":"2019-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1146/annurev-clinpsy-050718-095754","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36983033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 85

Bifactor and Hierarchical Models: Specification, Inference, and Interpretation. 双因素和层次模型:规范、推理和解释。

IF 18.4 1区心理学

Annual Review of Clinical Psychology Pub Date : 2019-05-07 Epub Date: 2019-01-16 DOI: 10.1146/annurev-clinpsy-050718-095522

Kristian E Markon

引用次数: 115