Clinical Anatomy最新文献_第5页

Mechanisms of cerebrospinal fluid secretion by the choroid plexus epithelium: Application to various intracranial pathologies. 脉络丛上皮分泌脑脊液的机制：在各种颅内病变中的应用。

IF 2.4 4区医学

Clinical Anatomy Pub Date : 2024-06-19 DOI: 10.1002/ca.24199

Laura Øllegaard Johnsen, Kathrine Abildskov Friis, Maria Kirstine Møller-Madsen, Helle Hasager Damkier

{"title":"Mechanisms of cerebrospinal fluid secretion by the choroid plexus epithelium: Application to various intracranial pathologies.","authors":"Laura Øllegaard Johnsen, Kathrine Abildskov Friis, Maria Kirstine Møller-Madsen, Helle Hasager Damkier","doi":"10.1002/ca.24199","DOIUrl":"https://doi.org/10.1002/ca.24199","url":null,"abstract":"The choroid plexus (CP) is a small yet highly active epithelial tissue located in the ventricles of the brain. It secretes most of the CSF that envelops the brain and spinal cord. The epithelial cells of the CP have a high fluid secretion rate and differ from many other secretory epithelia in the organization of several key ion transporters. One striking difference is the luminal location of, for example, the vital Na+-K+-ATPase. In recent years, there has been a renewed focus on the role of ion transporters in CP secretion. Several studies have indicated that increased membrane transport activity is implicated in disorders such as hydrocephalus, idiopathic intracranial hypertension, and posthemorrhagic sequelae. The importance of the CP membrane transporters in regulating the composition of the CSF has also been a focus in research in recent years, particularly as a regulator of breathing and hemodynamic parameters such as blood pressure. This review focuses on the role of the fundamental ion transporters involved in CSF secretion and its ion composition. It gives a brief overview of the established factors and controversies concerning ion transporters, and finally discusses future perspectives related to the role of these transporters in the CP epithelium.","PeriodicalId":50687,"journal":{"name":"Clinical Anatomy","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141421793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Validity of an ultrasound device to measure bone mineral density. 测量骨矿物质密度的超声波设备的有效性。

IF 2.4 4区医学

Clinical Anatomy Pub Date : 2024-06-15 DOI: 10.1002/ca.24187

Jessica L Puranda, Chris M Edwards, Vinicius M R Weber, Mohamed Aboudlal, Kevin Semeniuk, Kristi B Adamo

{"title":"Validity of an ultrasound device to measure bone mineral density.","authors":"Jessica L Puranda, Chris M Edwards, Vinicius M R Weber, Mohamed Aboudlal, Kevin Semeniuk, Kristi B Adamo","doi":"10.1002/ca.24187","DOIUrl":"https://doi.org/10.1002/ca.24187","url":null,"abstract":"This study aims to examine the validity and reliability of the UltraScan650™, a portable ultrasound device, used to measure BMD at the 1/3rd radius position. Fifty-two female first responders and healthcare providers were assessed using DXA (forearm, femur, lumbar, and total body) and the UltraScan650™. Fat and lean mass were also assessed using the DXA. Pearson correlations, Bland-Altman plots, t-tests, and linear regressions were used to assess validity. Intra-class correlation (ICC) coefficients were used to assess reliability. Inter-rater reliability and repeatability were good (ICC = 0.896 [0.818; 0.942], p < 0.001) and excellent (ICC = 0.917 [0.785; 0.989], p < 0.001), respectively. BMD as measured by the UltraScan650™ was weakly correlated to the DXA (r = 0.382 [0.121; 0.593], p = 0.0052). Bland-Altman plots revealed that the UltraScan650™ underestimated BMD (-0.0569 g/cm2), this was confirmed with a significant paired t-test (p < 0.001). A linear regression was performed (0.4744 × UltraScan650™ + 0.4170) to provide more information as to the issue of agreement. Bland-Altman plots revealed a negligible bias, supported by a paired t-test (p = 0.9978). Pearson's correlation revealed a significant relationship (r = -0.771 [-0.862; -0.631], p < 0.0001) between adjusted UltraScan650™-DXA and the average of the two scans (i.e., adjusted UltraScan650™ and DXA), suggesting a proportional constant error and proportional constant variability in measurements of BMD from the UltraScan650™. The UltraScan650™ is not a valid alternative to DXA for diagnostic purposes; however, the UltraScan650™ could be used as a screening tool in the clinical and research setting given the linear transformation is employed.","PeriodicalId":50687,"journal":{"name":"Clinical Anatomy","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141321844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical anatomy of the coronary venous system and relevance to retrograde cardioplegia and cardiac electrophysiological interventions. 冠状静脉系统的临床解剖以及与逆行性心脏麻痹和心脏电生理干预的相关性。

IF 2.4 4区医学

Clinical Anatomy Pub Date : 2024-06-12 DOI: 10.1002/ca.24195

Emeka Blessius Kesieme, Keith Gunn Buchan

引用次数: 0

The conceptus and its parts: ontogenetic recapitulation in early human development 概念体及其组成部分：人类早期发育的遗传再现。

IF 2.3 4区医学

Clinical Anatomy Pub Date : 2024-06-12 DOI: 10.1002/ca.24194

Brian Freeman

{"title":"The conceptus and its parts: ontogenetic recapitulation in early human development","authors":"Brian Freeman","doi":"10.1002/ca.24194","DOIUrl":"10.1002/ca.24194","url":null,"abstract":"Our understanding of the processes of human development that occur during and just after implantation is still incomplete. The anatomical studies by Erich Blechschmidt (1904–1992) at the University of Göttingen demonstrate the uniqueness and beauty of the early stages of individual human development or ontogeny. The interpretations of human embryology by Blechschmidt offer a simple unifying hypothesis: metabolic and biomechanical events are repeated, and this can be described as an ontogenetic recapitulation. This commentary provides a rationale for using some older terms and introducing new ones in the description of early human development. The product of conception is a conceptus; the outer part of the conceptus is the ectoblast and everything inside is the endoblast; the endocyst arises in the endoblast when the future amniotic fluid is forming. The human embryo arises from the innermost part of the endocyst. Terms such as morula, gastrula, and cyema, which are imported from zoology and ignore the role of the zona pellucida and constrained fluid compartments in the conceptus, can be avoided.","PeriodicalId":50687,"journal":{"name":"Clinical Anatomy","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ca.24194","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141312155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Upper end of the central canal of the human spinal cord: Quantitative anatomical study and 3D modeling. 人类脊髓中央管上端：定量解剖学研究和三维建模。

IF 2.4 4区医学

Clinical Anatomy Pub Date : 2024-06-11 DOI: 10.1002/ca.24196

Etienne Lefevre, Megane Le Quang, Guillaume Chotard, Steven Knafo, Pierre Mengelle, Yanis Taupin, Dominique Liguoro, Vincent Jecko, Jean-Rodolphe Vignes, Paul Roblot

{"title":"Upper end of the central canal of the human spinal cord: Quantitative anatomical study and 3D modeling.","authors":"Etienne Lefevre, Megane Le Quang, Guillaume Chotard, Steven Knafo, Pierre Mengelle, Yanis Taupin, Dominique Liguoro, Vincent Jecko, Jean-Rodolphe Vignes, Paul Roblot","doi":"10.1002/ca.24196","DOIUrl":"https://doi.org/10.1002/ca.24196","url":null,"abstract":"The upper end of the central canal of the human spinal cord has been repeatedly implicated in the pathogenesis of various diseases, yet its precise normal position in the medulla oblongata and upper cervical spinal cord remains unclear. The purpose of this study is to describe the anatomy of the upper end of the central canal with quantitative measurements and a three-dimensional (3D) model. Seven formalin-embalmed human brainstems were included, and the central canal was identified in serial axial histological sections using epithelial membrane antigen antibody staining. Measurements included the distances between the central canal (CC) and the anterior medullary fissure (AMF) and the posterior medullary sulcus (PMS). The surface and perimeter of the CC and the spinal cord were calculated, and its anterior-posterior and maximum lateral lengths were measured for 3D modeling. The upper end of the CC was identified in six specimens, extending from the apertura canalis centralis (ACC) to its final position in the cervical cord. Positioned on the midline, it reaches its final location approximately 15 mm below the obex. No specimen showed canal dilatation, focal stenosis, or evidence of syringomyelia. At 21 mm under the ACC in the cervical cord, the median distance from the CC to the AMF was 3.14 (2.54-3.15) mm and from the CC to the PMS was 5.19 (4.52-5.43) mm, with a progressive shift from the posterior limit to the anterior third of the cervical spinal cord. The median area of the CC was consistently less than 0.1 mm2. The upper end of the CC originates at the ACC, in the posterior part of the MO, and reaches its normal position in the anterior third of the cervical spinal cord less than 2 cm below the obex. Establishing the normal position of the upper end of this canal is crucial for understanding its possible involvement in cranio-cervical junction pathologies.","PeriodicalId":50687,"journal":{"name":"Clinical Anatomy","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141302071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Superficial retrocalcaneal bursae and nerves: From anatomy to ultrasound-guided procedures. 踝后浅滑囊和神经：从解剖学到超声引导手术。

IF 2.4 4区医学

Clinical Anatomy Pub Date : 2024-06-11 DOI: 10.1002/ca.24193

Vincenzo Ricci, Ke-Vin Chang, Ondřej Naňka, Levent Özçakar

{"title":"Superficial retrocalcaneal bursae and nerves: From anatomy to ultrasound-guided procedures.","authors":"Vincenzo Ricci, Ke-Vin Chang, Ondřej Naňka, Levent Özçakar","doi":"10.1002/ca.24193","DOIUrl":"https://doi.org/10.1002/ca.24193","url":null,"abstract":"The pertinent literature widely describes ultrasound-guided procedures targeting the retrocalcaneal bursa and the tendon tissue to manage insertional Achilles tendinopathy. Synovial bursae and cutaneous nerves of the superficial retrocalcaneal pad are often overlooked pain generators and are poorly considered by clinicians and surgeons. A layer-by-layer dissection of the superficial soft tissues in the retrocalcaneal region of two fresh frozen cadavers was matched with historical anatomical tables of the textbook Traite d'Anatomie Topographique Avec Applications Médico-Chirurgicales (1909 by Testut and Jacob). An accurate and detailed description of the superficial retrocalcaneal pad with its synovial bursae and cutaneous nerves was provided. Cadaveric dissections confirmed the compartmentalized architecture of the superficial retrocalcaneal fat pad and its histological continuum with the superficial lamina of the crural fascia. Superficial synovial tissue islands have been demonstrated on the posterior aspect of the Achilles tendon in one cadaver and on the posterolateral surface of the tendon in the other one. Digitalization of the original anatomical tables of the textbook Traite d'Anatomie Topographique Avec Applications Médico-Chirurgicales (1909 by Testut and Jacob) showed five potential locations of the superficial calcaneal bursa and a superficial retrocalcaneal nerve plexus within the Achilles tendon-fat pad interface. In clinical practice, in addition to the previously described interventions regarding the retrocalcaneal bursa and the tendon tissue, ultrasound-guided procedures targeting the synovial and neural tissues of the superficial retrocalcaneal pad should be considered to optimize the management of insertional Achilles tendinopathy.","PeriodicalId":50687,"journal":{"name":"Clinical Anatomy","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141302070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Anatomical evaluation of the superficial medial collateral ligament distal tibial attachment of the knee. 膝关节浅内侧副韧带胫骨远端附着处的解剖学评估。

IF 2.4 4区医学

Clinical Anatomy Pub Date : 2024-06-06 DOI: 10.1002/ca.24192

Keishiro Kikuchi, Kosuke Tabuchi, Seiichi Inoue, Akihiro Yamashita, Shotaro Kinouchi, Ryuki Hashida, Joe Iwanaga, Koichi Watanabe, R Shane Tubbs, Takahiro Okawa, Koji Hiraoka

{"title":"Anatomical evaluation of the superficial medial collateral ligament distal tibial attachment of the knee.","authors":"Keishiro Kikuchi, Kosuke Tabuchi, Seiichi Inoue, Akihiro Yamashita, Shotaro Kinouchi, Ryuki Hashida, Joe Iwanaga, Koichi Watanabe, R Shane Tubbs, Takahiro Okawa, Koji Hiraoka","doi":"10.1002/ca.24192","DOIUrl":"https://doi.org/10.1002/ca.24192","url":null,"abstract":"This study aimed to evaluate the superficial medial collateral ligament distal tibial attachment (sMCL-dTA) morphologically and morphometrically. Seventeen unpaired formalin-fixed cadaveric knees were used. The sMCL was divided into anterior and posterior sections in the paracoronal plane along the midline of the sMCL. The distance from the medial edge of the tibial plateau and the joint line to the proximal margin, center, and distal margin of the sMCL-dTA and the length of the sMCL-dTA were measured in the anterior section, respectively. The sMCL-dTA was histologically observed in the posterior section with hematoxylin and eosin and Masson's trichrome staining. The distance from the medial edge of the tibial plateauto the proximal margin, center, and distal margin of the sMCL-dTA were 38.1 ± 4.2, 49.7 ± 4.4, and 61.5 ± 5.1 mm, respectively. The perpendicular distance from the joint line to the proximal margin, center, and distal margin of the sMCL-dTA were 36.1 ± 4.0, 47.4 ± 4.2, and 59.1 ± 4.8 mm, respectively. The length of the sMCL-dTA was 23.6 ± 3.2 mm. Histologically, the sMCL-dTA was formed by two layers of collagen fibers: the unidirectional fibrous layer and the multidirectional fibrous layer. The respective thicknesses of the two layers both decreased distally. The anatomical location, the length, and the attachment morphology of sMCL-dTA have been clarified using human cadaveric knees. Anatomical data in the present study contribute to the quality of surgery associated with sMCL-dTA.","PeriodicalId":50687,"journal":{"name":"Clinical Anatomy","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141285212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

“Anatomie noe question is absolutely necessary to a Chirurgen” "解剖学对外科医师来说是绝对必要的"。

IF 2.4 4区医学

Clinical Anatomy Pub Date : 2024-06-06 DOI: 10.1002/ca.24189

R. Shane Tubbs

引用次数: 0

Facilitating active learning of sectional anatomy with technology-enhanced small-group tasks: Assessment of knowledge gains, technology usability, and students' perceptions 通过技术强化的小组任务促进主动学习剖面解剖学：对知识收获、技术可用性和学生看法的评估。

IF 2.3 4区医学

Clinical Anatomy Pub Date : 2024-06-06 DOI: 10.1002/ca.24190

Guilherme R. B. C. Fonseca, George L. Tipoe, Fraide A. Ganotice Jr

{"title":"Facilitating active learning of sectional anatomy with technology-enhanced small-group tasks: Assessment of knowledge gains, technology usability, and students' perceptions","authors":"Guilherme R. B. C. Fonseca, George L. Tipoe, Fraide A. Ganotice Jr","doi":"10.1002/ca.24190","DOIUrl":"10.1002/ca.24190","url":null,"abstract":"Learning 2D sectional anatomy facilitates the comprehension of 3D anatomical structures, anatomical relationships, and radiological anatomy. However, the efficacy of technology-enhanced collaborative instructional activities in sectional anatomy remains unclear, especially if theoretical frameworks, namely the Cognitive Theory of Multimedia Learning (CTML), are applied in instructional design. Thus, this study compared the educational impact of distinct 45-min-long technology-enhanced collaborative learning tasks in sectional anatomy. A sample of 115 first-year medical students was randomly divided into three experimental groups that used different supporting technologies to learn the sectional anatomy of the chest: IMAIOS e-learning platform and Microsoft Surface Hub (n = 37); anatomage table (n = 38); anatomage table with CTML-based presets (n = 40). Prelearning and postlearning tests revealed that significant knowledge gains in sectional anatomy were obtained by all groups even though no inter-group differences were found. Moreover, a five-point Likert scale questionnaire showed that the learning session was highly valued by all participants and that users of the anatomage with CTML-based presets reported higher enjoyment than users of the IMAIOS system (mean difference = 0.400; p = 0.037). In addition, students using the IMAIOS system and the anatomage with CTML-based presets provided System Usability Scale (SUS) scores of 67.64 and 67.69, respectively, reaching the benchmark of usability. By contrast, students using the anatomage table without presets awarded a SUS score of 64.14. These results suggest that the integration of multimedia technologies in anatomy teaching and learning should be grounded on CTML principles of instructional design. Otherwise, students' perceptions of ed-tech usability are potentially hindered.","PeriodicalId":50687,"journal":{"name":"Clinical Anatomy","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ca.24190","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141285213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Enhancing students' agency in learning anatomy vocabulary with a formative intervention design 利用形成性干预设计增强学生学习解剖学词汇的主动性。

IF 2.3 4区医学

Clinical Anatomy Pub Date : 2024-05-29 DOI: 10.1002/ca.24188

Helen E. Ritchie, Hongzhi Yang, Elizabeth Hegedus

{"title":"Enhancing students' agency in learning anatomy vocabulary with a formative intervention design","authors":"Helen E. Ritchie, Hongzhi Yang, Elizabeth Hegedus","doi":"10.1002/ca.24188","DOIUrl":"10.1002/ca.24188","url":null,"abstract":"One of the major challenges for health science students is the rapid acquisition of a new vocabulary in anatomy comprising several hundred new words. Research has shown that vocabulary learning can be improved when students are directed to vocabulary strategies. This paper reported a study with a formative intervention design inspired by Vygotsky's method of double stimulation. In this design, the students were put in a structured situation that invited them to identify the challenges in learning anatomy and then provided them with active guidance and a range of anatomy vocabulary learning strategies that scaffolded them to work out a solution to the challenge and develop their individualized anatomy learning resources. The data were collected from surveys, pre and postquiz results, and group discussion transcripts. The results revealed students perceived one of the main challenges in learning anatomy was learning, memorizing, and remembering many new words. A key finding in our study was that the formative intervention enhanced students' agency in creating resources for learning anatomy vocabulary. In addition, the development of their understanding showed a recursive form: from concrete experiences to abstract concepts and then to concrete new practices.","PeriodicalId":50687,"journal":{"name":"Clinical Anatomy","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ca.24188","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141161279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0