The Discovery of the Pericytes: A Historical Note.

IF 2.3 4区医学 Q1 ANATOMY & MORPHOLOGY

Clinical Anatomy Pub Date : 2025-05-10 DOI:10.1002/ca.24291

Domenico Ribatti

引用次数: 0

Abstract

Pericytes are adventitial cells located within the basement membranes of capillaries and post-capillary venules. Because they have multiple cytoplasmic processes and distinctive cytoskeletal elements, and envelope endothelial cells, pericytes are considered cells that stabilize the vessel wall, controlling endothelial cell proliferation and thereby the growth of new capillaries. Several molecules are involved in controlling and modulating the interactions between pericytes and endothelial cells, such as platelet-derived growth factor beta (PDGFβ), transforming growth factor beta (TGFβ), and angiopoietins (Angs).

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周细胞的发现：一个历史笔记。

周细胞是位于毛细血管基底膜和毛细血管后小静脉内的外体层细胞。由于周细胞具有多个细胞质过程和独特的细胞骨架元件，以及包膜内皮细胞，因此周细胞被认为是稳定血管壁的细胞，控制内皮细胞的增殖，从而控制新毛细血管的生长。一些分子参与控制和调节周细胞和内皮细胞之间的相互作用，如血小板衍生生长因子β (PDGFβ)、转化生长因子β (TGFβ)和血管生成素（Angs）。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical Anatomy 医学-解剖学与形态学

CiteScore

5.50

自引率

12.50%

发文量

154

审稿时长

3 months

期刊介绍： Clinical Anatomy is the Official Journal of the American Association of Clinical Anatomists and the British Association of Clinical Anatomists. The goal of Clinical Anatomy is to provide a medium for the exchange of current information between anatomists and clinicians. This journal embraces anatomy in all its aspects as applied to medical practice. Furthermore, the journal assists physicians and other health care providers in keeping abreast of new methodologies for patient management and informs educators of new developments in clinical anatomy and teaching techniques. Clinical Anatomy publishes original and review articles of scientific, clinical, and educational interest. Papers covering the application of anatomic principles to the solution of clinical problems and/or the application of clinical observations to expand anatomic knowledge are welcomed.