Clinica Terapeutica最新文献

{"title":"HDL cholesterol as a predictor of cardiovascular risk factors and glycaemic control: a cross-sectional observational study.","authors":"S V Hegde, K S Rashmi, R Kandimalla, P P Shetty, G V Bernhardt, S M Kotian, B Ashwith, Y K Hebbar","doi":"10.7417/CT.2025.5263","DOIUrl":"10.7417/CT.2025.5263","url":null,"abstract":"<p><strong>Background: </strong>HDL-cholesterol is unanimously called good chole-sterol for its atheroprotective role. Lately, studies have shown a strong alliance between HDL-cholesterol levels, cardiovascular disease and diabetes mellitus. With this, present study aims to explore the prevalence of both high and low HDL-cholesterol levels in study population, and its association with lipid profile, fasting blood sugar, post prandial blood sugar and glycated haemoglobin levels.</p><p><strong>Methods: </strong>This cross-sectional observational study, encompassing 2080 patients, endeavors to conduct a comprehensive SWOT analysis elucidating the diagnostic and prognostic efficacy of HDL-cholesterol levels, with a specific focus on hyperalphalipoproteinemia, in the context of cardiovascular disease and diabetes mellitus. The study meticulously categorized 746 patients into two distinct groups: those with HDL-cholesterol levels below 40 mg/dL (n = 709) and those with levels surpassing 80 mg/dL (n = 37).</p><p><strong>Results: </strong>The study showed a comparatively low prevalence of hyperalphalipoproteinemia. Nonetheless, the study findings vindicate the concept of the detrimental effect of high levels of HDL choleste-rol on cardiovascular outcomes. Hyperalphalipoproteinemia patients showed significant difference compared to the individuals with low HDL-cholesterol presenting elevated levels of total cholesterol. High triglyceride and VLDL were seen in patients with low HDL cholesterol. Both groups revealed a high LDL-cholesterol without any significant difference. However, both the categories demonstrated almost similar disparity in the glycemic parameters to be specific FBS, PPBS, HbA1c with no significant difference.</p><p><strong>Conclusions: </strong>High HDL-cholesterol levels are equally perilous as that of their lower levels. Hence both low & high HDL-cholesterol serves as predictor of cardiovascular risk factors and glycemic control.</p>","PeriodicalId":50686,"journal":{"name":"Clinica Terapeutica","volume":"176 5","pages":"544-549"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145139204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Value of FilmArray Pneumonia Panel plus in Managing Nosocomial Respiratory Infections in Hospitalized Patients: Cross-sectional study.","authors":"Omima Sayed Mohammed, Abdulmabod Omar, Mohammad AbdElhameed Alwaseef, Hatem Mohamed Newishy, Medhat Ali Salah Abd Elghaffar, Zeinab Adawy, Mahmoud Ahmed Arfa, Tarek Abualkasem Abualwafa Mohammed, Mohamed Abd Elrahman Abd Elkader Elbakery, Usama Abdalla, Hanem Mohamed Badawy, Mohammad Abd Elhalem Abd El Razik, Huda Ali Abdalrahim Alzubir, Fawzia A Sharaf, Bothayna I Saleh, Abdullah Mustafa Ibrahim Gaafar, Bassam Abdellatif Mahmoud Elsayed, Esam M Shawky, Mohamed Mahmoud Abdelfattah Abdelrahman, Mai Mosad Morsy, Mohamed Mounir Ahmed Rizk, Nahla Mohammed Eldeeb, Ahmed Rizk Elkholy, Wageih Salem ElNaghy, Ola A Elshora, Hossam M Farid El-Zamek, Ahmed R I Ali, Mohamed Basiouny Yahia, Fatma Ibrahim Ismail Mayah, Ahmed M Ewis, Eid Mohammed, Ahmed Atef Ganna, Esraa El-Sayed AbdelMaksoud Elmahdy","doi":"10.7417/CT.2025.5276","DOIUrl":"10.7417/CT.2025.5276","url":null,"abstract":"<p><strong>Background: </strong>The traditional reliance on slow culture-based diagnostics often leads to delays in targeted therapy and the overuse of broad-spectrum antibiotics, aggravating the problem of antimicrobial resistance.</p><p><strong>Aim: </strong>To compare the BioFire, FilmArray Pneumonia Panel plus (FA-PneumobioMérieux) assay with a conventional diagnostic tools, including culture and VITEK 2 (bioMérieux), to identify microorganisms in critically ill patients (severe pulmonary infection) to get the best results within a short period.</p><p><strong>Methods: </strong>An observational, comparative cross-sectional, hospital-based investigation was carried out at the microbiology unit of the clinical pathology department of Alazhar University hospitals. Lower respiratory tract samples were collected from patients with hospital-acquired pneumonia and ICU admissions. Conventional culture was carried out for all specimens. Susceptibility testing was performed on all specimens using the VITEK 2 system (bioMérieux). The BioFire FA-Pneumo assay was conducted according to the manufacturer's instructions.</p><p><strong>Results: </strong>Out of 60 patients with pneumonia 90% of specimens were sputum samples. For all examined pathogens, there was no statistically significant difference between the detection rates of Multiplex PCR and Vitek methods (P-value >0.05). The most prevalent resistant gene detected by Multiplex PCR was gene (blaNDM-1 ), found in 23.3% (n=14) of the samples, followed by OXA-48-like, which was found in 15% (n=9) of the samples. The detection of CTX-, CTX-M, KPC, mecA/C, and MREJ, VIM resistant genes were at lower frequencies.</p><p><strong>Conclusion: </strong>The FilmArray Pneumonia Panel Plus (FA-Pneumo) is a rapid molecular diagnostic tool designed to overcome the limitations of conventional methods by quickly identifying a broad range of pathogens and resistance genes. The capability of FA-Pneumo to rapidly identify both pathogens and key resistance genes provides a significant advantage for clinical decision-making.</p>","PeriodicalId":50686,"journal":{"name":"Clinica Terapeutica","volume":"176 5","pages":"645-650"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145138915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Medico legal consideration about the follow-up in multiple sclerosis: enhanced or non enhanced MRI?","authors":"M Salducci, V Martines, M S Simonelli","doi":"10.7417/CT.2025.5281","DOIUrl":"10.7417/CT.2025.5281","url":null,"abstract":"<p><strong>Background: </strong>Scientific literature supports that, in cases of multiple sclerosis, follow-up for clinically stable patients can be performed with an non-enhanced magnetic resonance examination (MRI). One of the reasons for applying the contrast medium protocol, even in cronic patients, is the fear of legal disputes.</p><p><strong>Objectives: </strong>Our objective is to to analyze the risks of performing a non-enhanced MRI control test. In multiple sclerosis (MS) cronic patients, the control test monitors the evolution of the disease. The MRI show the evolution of the disease represented by the appearance of new lesions or the extension in size of already known lesions.</p><p><strong>Results: </strong>The only situation where the use of contrast medium can provide further information not deducible from the baseline examination is the reactivation of one or more lesions already present without the appearance of new lesions. This situation is extremely rare. Furthermore, the interval between one check-up to the next is time that isn't significant with respect to the evolution of a chronic disease even if a therapy is modified or started late.</p><p><strong>Conclusion: </strong>The fear of incurring legal disputes related to the failure to administer contrast medium has no reason to influence the professional choices of radiologists.</p>","PeriodicalId":50686,"journal":{"name":"Clinica Terapeutica","volume":"176 5","pages":"675-677"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145139265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"MR Elastography of Pituitary Macroadenomas with Intraoperative and Immunofluorescence correlation: A Feasibility study along with Literature Review.","authors":"Anjali Raj, Sameer Peer, Varun Aggarwal, Nishant Chakravorty, Pooja Singh, Amit Narang, Paramdeep Singh","doi":"10.7417/CT.2025.5278","DOIUrl":"https://doi.org/10.7417/CT.2025.5278","url":null,"abstract":"<p><strong>Background: </strong>Pituitary adenomas (PA) are a prevalent type of intracranial space-occupying lesions (SOLs). Most pituitary tumours exhibit soft consistency, and some of them show firm or hard characteristics. Therefore, it is important to discern the preoperative consistency of these tumours to select appropriate surgical interventions to reduce the likelihood of residual or recurrent disease. Magnetic resonance elastography (MRE) presents a promising novel technique for assessing the preoperative consistency of adenomas. This study investigated MRE's potential utility in determining preoperative tumour consistency in PAs.</p><p><strong>Method: </strong>This prospective study included cases of pituitary macroadenomas (PMA) (size > 2 cm). Preoperative measurements of tumour stiffness using MRE were conducted. Neurosurgeons were blindfolded to radiological MRE tumour consistency and graded tumour consistency during surgery that was documented in operative notes. A correlation between the preoperative MRE tumour consistency to surgical consistency and collagen I & III values on immunofluorescence was done.</p><p><strong>Results: </strong>Nine patients were included in the study, with a mean age of 52±9.6 years. Eight of the nine patients underwent Endoscopic Trans-Nasal Trans-Sphenoidal (TNTS) surgery, and one underwent craniotomy. Based on surgical tumour consistency, six patients were categorized as soft, and three as firm. The mean MRE value was 1.99±0.53 (1.33-3.23) kPa. A Comparison between surgical tumour consistency and MRE showed moderate agreement with a Cohen's Kappa value of 0.769. The comparison of MRE values with collagen I showed a weak positive correlation (Pearson correlation value = 0.417), while the correlation with collagen III demonstrated a positive correlation (Pearson correlation value = 0.556).</p><p><strong>Conclusion: </strong>MRE can help in the pre-operative prediction of the consistency of the pituitary macroadenomas with a moderate degree of agreement between pre-operative MRE and operative characterization of tumour consistency by the surgeons.</p>","PeriodicalId":50686,"journal":{"name":"Clinica Terapeutica","volume":"176 5","pages":"655-664"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145139220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Popularity of heated-tobacco products and e-cigarettes among medical school students in Rome, Italy: factors associated with use and attitudes towards quitting.","authors":"M S Milella, A Sansone, S Basili, A K Ferketich, G La Torre, G Battaglia, M C Grassi","doi":"10.7417/CT.2025.5271","DOIUrl":"10.7417/CT.2025.5271","url":null,"abstract":"<p><strong>Background: </strong>Future health-care providers will counsel and deliver interventions on nicotine dependence based on their own perceptions and behaviors. The present study aims to assess changes in prevalence of use of nicotine-containing products and attitudes towards quitting use among medical students.</p><p><strong>Methods: </strong>A cross-sectional survey was performed during academic years 2019-2020 and 2021-2022 (total n=1949). Multivariable regression was conducted to examine factors associated with current product used.</p><p><strong>Results: </strong>Prevalence of current exclusive use of heated tobacco products significantly increased (from 3.1% to 6.6%), also in dual use with traditional cigarettes (from 0.6% to 1.9%). Exclusive use of traditional cigarettes declined (from 14.5% to 11.4%). Female students were more likely to currently use heated tobacco products. Knowledge in tobacco dependence and severity of dependence were also associated with use of newer tobacco products. Intentions to quit using in the near future remained low across academic years (≈30%), independently from product used.</p><p><strong>Conclusions: </strong>The results indicate a rapid switch towards newer tobacco products and potential gender-related risk factors for the use of heated-tobacco products. Implementation of up-to-date medical school training on nicotine dependence and on new nicotine-containing products is warranted, to educate future health promoters and prevent tobacco-related harm.</p>","PeriodicalId":50686,"journal":{"name":"Clinica Terapeutica","volume":"176 5","pages":"601-608"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145138917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Periprosthetic Hip Infections: the possible role of ultrasonography.","authors":"L Di Sante, F Agostini, D De Meo, A Savina, M Conti, A Fisicaro, G Iudicelli, A Altarocca, M Mangone, M Paoloni","doi":"10.7417/CT.2025.5269","DOIUrl":"10.7417/CT.2025.5269","url":null,"abstract":"<p><strong>Background: </strong>Periprosthetic joint infections (PJI) of the hip represent a severe and debilitating complication following hip arthroplasty, associated with significant morbidity and healthcare costs. The early diagnosis of PJI is challenging due to its nonspecific clinical signs and symptoms, often overlapping with non-infectious conditions.</p><p><strong>Methods: </strong>Our study was conducted on 30 patients with periprosthetic hip infections to analyze specific ultrasonographic patterns. Ultrasound examinations were performed by experienced sonographers, blinded to patient clinical and laboratory data. The assessment included joint effusion, periprosthetic fluid collections, synovial thickening, fistulous tracts, and hyperemia using Doppler imaging, correlated with laboratory markers, such as C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), D-dimer and white blood cell count (WBC).</p><p><strong>Results: </strong>The most frequently observed ultrasonographic patterns associated with PJI were intra- and peri-articular tracts (80%), and joint effusion (73.33%), with supra-fascial effusion (60%) and sub-fascial effusion (56.67%). Doppler ultrasound revealed prosthetic hyperemia in 50% of patients and tissue hyperemia in 20%. Elevated CRP and ESR levels were present in 80% and 93.33% of patients, respectively. Indicative WBC count were found on the entirety of the examined sample and indicative D-dimer levels were present in 83.33% of patients.</p><p><strong>Conclusions: </strong>Ultrasonography, enhanced by Doppler imaging, is a valuable diagnostic modality for assessing periprosthetic joint infections of the hip. The presence of intra- and peri-articular tracts and joint effusion were the most consistent findings. Integrating ultra-sonographic findings with laboratory tests is crucial for the accurate and timely diagnosis of PJI, and further multicenter studies are required to standardize its use and improve its clinical applicability.</p>","PeriodicalId":50686,"journal":{"name":"Clinica Terapeutica","volume":"176 5","pages":"582-589"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145138993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Hypothyroidism on Lipid Profile and Liver Enzymes: Implications In Non-Alcoholic Fatty Liver Disease.","authors":"S V Hegde, A S K Bhattam, A Sequeira, R Kandimalla, C Siripuram, S Konka, S Kumar, A Ignasimuthu, S S Suvarna, P P Shetty","doi":"10.7417/CT.2025.5272","DOIUrl":"10.7417/CT.2025.5272","url":null,"abstract":"<p><strong>Background: </strong>Hypothyroidism is known to affect lipid metabolism, and its association with non-alcoholic fatty liver disease (NAFLD) is of growing interest. This study aimed to evaluate the effects of hypothyroidism on lipid profiles and liver enzymes, with a particular focus on the implications for NAFLD.</p><p><strong>Methods: </strong>A case-control study was conducted with 74 participants, including 44 hypothyroid patients (22 with overt hypothyroidism and 22 with subclinical hypothyroidism) and 30 healthy controls. Participants were aged 20-65 years, and a detailed clinical history was obtained to exclude comorbid conditions such as diabetes, liver disorders, alcohol consumption, and acute inflammatory diseases. Waist circumference, BMI, and blood pressure were measured, and venous blood samples were drawn for analysis. Thyroid hormones (TSH, T3, T4) were measured using enzyme-linked fluorescent assays, while lipid profile (cholesterol, triglycerides) and liver enzymes (ALT, AST, ALP) were assessed using an automated clinical analyzer. Statistical analysis included ANOVA, post-hoc tests, and correlation analysis.</p><p><strong>Results: </strong>Significant differences were observed in TSH levels between the groups (p < 0.001), with the overt hypothyroid group showing the highest mean TSH. BMI was higher in the hypothyroid groups compared to controls, but the difference was not statistically significant (p = 0.065). Cholesterol levels were significantly elevated in both the overt and subclinical hypothyroid groups (p = 0.032), with post-hoc analysis revealing significant differences between the overt hypothyroid group and controls (p = 0.016). No significant differences were found in triglyceride levels across groups (p = 0.191). Outlier analysis of TSH levels revealed several extreme values in the overt hypothyroid group, reflecting more severe thyroid dysfunction. Correlation analysis showed a weak positive correlation between TSH and BMI (r = 0.18, p = 0.044), while no significant correlations were observed between TSH and age, or BMI and age.</p><p><strong>Conclusion: </strong>Hypothyroidism, particularly overt hypothyroidism, is associated with altered lipid metabolism and higher cholesterol levels. These changes may contribute to an increased risk of NAFLD in individuals with thyroid dysfunction.</p>","PeriodicalId":50686,"journal":{"name":"Clinica Terapeutica","volume":"176 5","pages":"609-615"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145139284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"History of biomechanical orthodontics in Italy.","authors":"M A A Karaboue, A Ballini, M E Bizzoca, G Capolongo, L Nigro, C Cagnano, S Florio, S M Marchesiello, E Mascolo, A Cutaio, C Consorte, C De Carlo Chimienti, G V Lacasella","doi":"10.7417/CT.2025.5277","DOIUrl":"10.7417/CT.2025.5277","url":null,"abstract":"<p><strong>Abstract: </strong>From the anatomical studies of Renaissance artists to the advent of modern orthodontic biomechanics, the Italian contribution to orthodontics reflects a rich history of innovation and scientific insight. This review traces the historical development of biomechanical principles in Italian orthodontics, highlighting major figures such as Edmondo Muzj and Domenico Arnone. Beginning with early cephalometric and biometric explorations in the early 20th century, it covers the evolution of diagnostic tools, the influence of international techniques like the Begg method, and the institutional milestones that shaped the field. Italy's interdisciplinary approach, incorporating anthropometry, biomechanics, and aesthetics, continues to inform clinical orthodontic practice today.</p>","PeriodicalId":50686,"journal":{"name":"Clinica Terapeutica","volume":"176 5","pages":"651-654"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145139292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Art of Observation - How Art Enhances Healthcare Professionals' Skills.","authors":"V Ferrara, P Pozzilli, L De Gara, T Mancuso, G La Torre, M Guarino","doi":"10.7417/CT.2025.5280","DOIUrl":"https://doi.org/10.7417/CT.2025.5280","url":null,"abstract":"<p><strong>Abstract: </strong>On November 20-21, 2024, Campus Bio-Medico University of Rome hosted Italy's first International Forum dedicated to the integration of the humanities, particularly visual arts, into medical, nursing, and healthcare education. An expanding body of scientific evidence confirms that art plays a crucial role in health education: enhancing caregivers' skills, strengthening the patient-caregiver relationship, enriching therapeutic pathways, and promoting overall well-being, thus reducing the risk of stress and burnout.</p>","PeriodicalId":50686,"journal":{"name":"Clinica Terapeutica","volume":"176 5","pages":"672-674"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145138981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mobile device based educational support for breast feeding technique in multigravida mothers improved exclusive breast feeding practice during the COVID-19 pandemic -A facility based single-Blind, Parallel-Randomised, Controlled Trial.","authors":"Keerthi Raj, Nitin Joseph, Suchetha S Rao, Nutan Kamath","doi":"10.7417/CT.2025.5262","DOIUrl":"https://doi.org/10.7417/CT.2025.5262","url":null,"abstract":"<p><strong>Background: </strong>COVID 19 pandemic disrupted the daily life for pregnant women, and maternity care services. During the lockdown, social isolation rendered one to one support difficult and there has been a rapid switch to the access of the support provided remotely including in the domains of breastfeeding support. We aimed to assess the breastfeeding behaviour following education through a video on breastfeeding techniques using smartphones.</p><p><strong>Methods: </strong>A facility-based randomized controlled trial enrolled 144 multigravida postnatal mothers in a community maternity centre. The Intervention group was educated antenatally with a video on breastfeeding techniques and shared to the mother's smartphone through \"Whatsapp application\". All mothers received education with ongoing public health programs. Breastfeeding self-confidence assessed by the breastfeeding self-efficacy scale short form (BSES-SF) and breast-feeding technique by Bristol breastfeeding assessment tool (BBAT) was assessed in both groups 24 -48 hours postpartum. Infant feeding practice was recorded telephonically at two, four and six months.</p><p><strong>Results: </strong>BSES-SF scores improved in both groups post-intervention.There was no statistically significant difference in breastfeeding technique assessed by the BBAT, post intervention. In the intervention group, the exclusive breast-feeding (EBF) rates at the end of two, four, and six months were significantly higher and mothers were 2.64 times more likely to exclusively breastfeed.</p><p><strong>Conclusion: </strong>Video-based health education in the peripartum period and self-reinforcement through availability of educational material on their smartphones improved the EBF rate.</p>","PeriodicalId":50686,"journal":{"name":"Clinica Terapeutica","volume":"176 5","pages":"537-543"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145139218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}