Clinica Terapeutica最新文献

{"title":"Physiotherapy rehabilitation in chronic low back pain.","authors":"Aida Zotaj, Rajmonda Milloshi, Selda Sokoli, Elda Cani, Enri Kaçi","doi":"10.7417/CT.2026.2103","DOIUrl":"10.7417/CT.2026.2103","url":null,"abstract":"<p><strong>Abstract: </strong>The aim of this study was to evaluate the effectiveness of Transfer of Energy Capacitive and Resistive (TECAR) therapy in combination with massage therapy for the treatment of chronic low back pain. Particular attention was given to assessing the impact of this innovative approach - based on the principle of capacitive and resistive electrical transfer - on tissue regeneration, inflammation reduction, pain relief, as well as the stimulation of blood circulation and metabolic processes. The study involved 35 patients aged 30 to 80 years who had suffered from chronic low back pain for more than 12 weeks. The visual analogue scale for pain and the Roland-Morris Disability Questionnaire were used to assess the outcomes. A comparison between traditional rehabilitation using massage therapy alone and a combination of Tecar therapy and massage therapy revealed that the innovative approach produced significantly better results compared to conventional treatment methods. Patients undergoing rehabilitation with Tecar therapy reported a reduction in pain severity from \"severe\" to \"moderate\" and a decrease in disability levels, as measured by the Roland-Morris questionnaire. Tecar therapy is an innovative physiotherapy method that utilises a high-frequency electromagnetic field to activate natural processes of tissue repair, alleviate pain, and reduce inflammation. The method is based on the stimulation of energy exchange between the electrodes of the device, which directly affects the patient's tissues. This study confirms that Tecar therapy, in combination with massage therapy, is an effective method for the rehabilitation of patients with chronic low back pain, enabling rapid functional recovery and pain reduction.</p>","PeriodicalId":50686,"journal":{"name":"Clinica Terapeutica","volume":"177 5","pages":"1040-1048"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148851698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Beyond Exposure: A Comprehensive Vision for Healthcare Worker Protection.","authors":"Fabiola Del Parco","doi":"10.7417/CT.2026.2101","DOIUrl":"10.7417/CT.2026.2101","url":null,"abstract":"<p><strong>Abstract: </strong>The protection of healthcare workers (HCWs) requires an integrated approach addressing both traditional occupational hazards and psychosocial challenges. The COVID-19 pandemic demonstrated that HCW safety cannot rely solely on infection prevention but must also consider work-related stress, burnout, and organisational determinants of well-being. Contact tracing supported the prevention of SARS-CoV-2 transmission, while validated tools such as the Mini-Z questionnaire enabled the assessment of stress and burnout. Evidence highlights the association between occupational stress and poorer health-related quality of life, supporting the need for comprehensive strategies. The Total Worker Health® framework integrates occupational safety, health promotion, and organisational well-being, combining individual interventions with organisational measures. A multidimensional approach based on surveillance, assessment, and evidence-based interventions is essential to promote resilient healthcare systems and sustainable working conditions.</p>","PeriodicalId":50686,"journal":{"name":"Clinica Terapeutica","volume":"177 5","pages":"1025-1027"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148851893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"From Infection Control to Healthcare System Resilience: Lessons Learned from SARS-CoV-2 Research in Healthcare Workers.","authors":"Nunzia Naddeo, Gaia Faraci","doi":"10.7417/CT.2026.2125","DOIUrl":"10.7417/CT.2026.2125","url":null,"abstract":"<p><strong>Abstract: </strong>The COVID-19 pandemic placed unprecedented pressure on healthcare systems and exposed healthcare workers (HCWs) to biological hazards, organizational pressures, and psychological strain. Evidence generated during the emergency shows that HCW protection cannot rely on isolated measures, but requires an integrated framework combining epidemiological surveillance, contact tracing, infection prevention and control, vaccination, occupational health, and workforce support. Contact tracing helped identify occupational exposures and clarify how duration, proximity, and inadequate use of personal protective equipment jointly shaped infection risk. Subsequent studies of reinfection showed that susceptibility reflected the interaction of viral circulation, individual immunity, and vaccination status. Vaccination reduced the clinical impact of SARS-CoV-2 and supported service continuity, although uptake depended on trust, communication, and management of adverse event concerns. The pandemic also highlighted substantial economic consequences and a high burden of psychological distress and burnout among HCWs. Building on this evidence, future preparedness should translate these lessons into permanent, adaptable infrastructure rather than temporary emergency arrangements, integrating interoperable, AI-assisted surveillance capable of combining occupational, diagnostic, vaccination, and genomic data to detect emerging risks early, while ensuring robust data governance and human oversight. Equally central is the need to address long-term workforce vulnerabilities, including Long COVID, attrition, and burnout, through early identification, rehabilitation, flexible return-to-work models, and sustained psychosocial support. Achieving this requires structured multidisciplinary collaboration among occupational medicine, infection control, epidemiology, mental health, and digital health specialists, moving from fragmented infection-control protocols to an integrated, proactive, and learning-oriented preparedness strategy. Protecting HCWs is therefore not only an occupational safety priority but a foundational prerequisite for safe, equitable, and sustainable healthcare delivery during future infectious threats.</p>","PeriodicalId":50686,"journal":{"name":"Clinica Terapeutica","volume":"177 5","pages":"1234-1237"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148851868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Hidden Cost of Sports Injuries: A Medico-Legal Perspective on Performance, Career and Contracts.","authors":"Giuseppe Basile, Luca Bianco Prevot, Michela Basile, Livio Pietro Tronconi","doi":"10.7417/CT.2026.2100","DOIUrl":"10.7417/CT.2026.2100","url":null,"abstract":"<p><strong>Abstract: </strong>The medico-legal assessment of sports injuries in professional athletes continues to rely on tools designed for an entirely different context. Permanent impairment tables measure the reduction in overall individual function, but not the loss of competitive performance, the reduction in expected athletic lifespan, or the impact on contracts and earnings. In this Editorial we argue that closing this gap does not require new, ad hoc composite indices, but a more rigorous and systematic integration of approaches already validated in the sports medicine and rehabilitation literature: objective quantification of the return-to-sport (RTS) deficit, obtained by comparing validated sport-specific functional and performance outcome measures recorded before and after injury; structured documentation of the rehabilitation pathway, including objective RTS criteria, time-to-RTS, and the psychological readiness to compete; and an evidence-based estimate of the economic and contractual impact, grounded in objective performance-analytics data rather than presumptive percentages. The integration of these indices with clinical-orthopaedic assessment may allow a more accurate definition of \"functional-professional\" damage in athletes, with significant implications for insurance, legal, and medico-legal practice. The aim is to promote a new multidisciplinary assessment model capable of bridging the traditional distinction between biological damage and economic loss, providing a more realistic and equitable measure of the consequences of sports trauma on athletes' careers.</p>","PeriodicalId":50686,"journal":{"name":"Clinica Terapeutica","volume":"177 5","pages":"1023-1024"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148851855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative study between contrast enhanced mammography and breast MRI in local pre-operative staging of invasive lobular carcinoma: A cross-sectional study.","authors":"Micheal Saber Nan Georgy, Randa Hossein Abdallah, Ahmed Gamal-Eldin Othman, Rana Mamdouh Naeim, Nermeen Nasry Halim Keriakos","doi":"10.7417/CT.2026.2122","DOIUrl":"10.7417/CT.2026.2122","url":null,"abstract":"<p><strong>Background: </strong>Invasive lobular carcinoma (ILC) is the second most common subtype of breast cancer and is often difficult to detect and accurately stage because of its infiltrative growth pattern, multifocality, multicentricity, and potential bilaterality. Accurate preoperative assessment of disease extent is essential for optimal surgical planning. Breast magnetic resonance imaging (MRI) is considered the reference imaging modality for staging breast cancer, while contrast-enhanced mammography (CEM) has emerged as a promising alternative with improved accessibility and lower cost.</p><p><strong>Objective: </strong>To compare the performance of contrast-enhanced mammography and breast MRI in the local preoperative staging of invasive lobular carcinoma and to evaluate their agreement with histopathological findings regarding lesion size, lesion number, multifocal-multicentric disease, and laterality.</p><p><strong>Methods: </strong>This cross-sectional study was conducted over 18 months and included 39 female patients with histopathologically confirmed invasive lobular carcinoma. Twenty-four patients underwent CEM and 27 underwent breast MRI, with 12 patients undergoing both examinations. Imaging findings were compared with postoperative histopathological results, which served as the reference standard. Agreement regarding lesion number, size of the largest lesion, multifocal-multicentric disease, and laterality was assessed using appropriate statistical analyses.</p><p><strong>Results: </strong>MRI demonstrated excellent agreement with pathology for lesion size classification (96.3%, κ=0.924), with high sensitivity (93.75%) and specificity (100%). In contrast, CEM significantly overestimated lesion size and showed moderate agreement (66.67%, κ=0.356), despite high sensitivity (90.91%). Both modalities showed strong performance in detecting multifocal-multicentric disease, with MRI demonstrating higher sensitivity (94.74%) and CEM higher specificity (100%). For laterality assessment, MRI achieved perfect agreement with pathology (100%), while CEM demonstrated excellent agreement (95.83%). Overall, MRI showed the closest concordance with pathological findings.</p><p><strong>Conclusions: </strong>Both CEM and MRI are effective imaging modalities for preoperative staging of invasive lobular carcinoma. MRI provides superior accuracy in assessing tumor size and disease extent and remains the preferred staging modality. However, CEM offers excellent performance in evaluating multifocality, multicentricity, and laterality, making it a valuable alternative when MRI is unavailable or contraindicated.</p>","PeriodicalId":50686,"journal":{"name":"Clinica Terapeutica","volume":"177 5","pages":"1201-1207"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148851953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dexamethasone Versus Dexmedetomidine as Adjuncts to Serratus Anterior Plane Block for Postoperative Analgesia After Modified Radical Mastectomy: A Randomized Clinical Trial.","authors":"Warda Demerdash Khalifa Ali, Elsayed M Elkarta, Mohammed El Sayed Abdel Hameed, Khaled Asem Allam, Gamal Eldin Adel Abdelhameed, Mohammed Abdulgadir Ageel, Mohamed Mahmoud Abdelfattah Abdelrahman, Murad Barakat, Ahmed Ibrahim Ali Sharaf, Ibrahim Hassaan, Abdallah Elzeiny, Eslam Abdelfattah, Raafat Mady, Zain Akhtar, Ahmed Shaaban","doi":"10.7417/CT.2026.2098","DOIUrl":"10.7417/CT.2026.2098","url":null,"abstract":"<p><strong>Background: </strong>Serratus anterior plane block (SAPB) is widely used for postoperative analgesia following modified radical mastectomy (MRM). Adjuvant drugs such as dexamethasone and dexmedetomidine may enhance its efficacy.</p><p><strong>Objective: </strong>To compare the analgesic efficacy of dexamethasone versus dexmedetomidine as adjuncts to SAPB in patients undergoing MRM.</p><p><strong>Methods: </strong>This randomized clinical study included 126 female patients undergoing MRM, allocated into two equal groups: dexamethasone (DXA) and dexmedetomidine (DMX). Outcomes included postoperative pain scores, analgesic consumption, sedation level, adverse effects, and recovery parameters.</p><p><strong>Results: </strong>The DXA group demonstrated significantly lower postoperative pain scores at all time points (p < 0.05), prolonged time to first rescue analgesia, reduced opioid consumption, shorter hospital stay, and lower chronic pain scores. Early postoperative sedation scores were higher in the DXA group but without clinical significance. No significant differences were observed in adverse effects between groups.</p><p><strong>Conclusion: </strong>Dexamethasone is superior to dexmedetomidine as an adjunct to SAPB in MRM, providing prolonged analgesia and improved recovery outcomes.</p>","PeriodicalId":50686,"journal":{"name":"Clinica Terapeutica","volume":"177 5","pages":"1009-1016"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148851860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The association of duration of yoga practice on the cognitive and psychological variables.","authors":"Das Anwesha, B Shetty Sneha, K Bhagyalakshmi, Arun Kumar Nayanatara, N Anupama","doi":"10.7417/CT.2026.2107","DOIUrl":"10.7417/CT.2026.2107","url":null,"abstract":"<p><strong>Purpose: </strong>Yoga is a holistic practice that integrating asanas, pranayama, and meditation promoting physical, psychological, and cognitive well-being. Long-term practice of yoga has been associated with various beneficial effects. However, the influence of the duration of yoga practice on cognitive and psychological outcomes remains inadequately understood.</p><p><strong>Method: </strong>This study was aimed to assess the impact of the duration of yoga practice on cognitive and psychological variables.</p><p><strong>Objectives: </strong>To evaluate the relationship between the duration of yoga practice and cognitive function and to assess its association with psychological variables.</p><p><strong>Methods: </strong>This cross-sectional study was conducted among 100 healthy yoga practitioners. Participants were divided into two groups: those practicing yoga for less than 6 months ( n=50) and those practicing for more than 6 months (n=50), with a minimum practice of 30 minutes per day for at least 4 days per week. Cognitive function , Perceived stress scale and Happiness Index Questionnaire.</p><p><strong>Results: </strong>The mean ages of participants in the <6 months and >6 months yoga practice groups were 34.43 ± 3.74 and 35.93 ± 4.49 years, respectively. Participants practicing yoga for more than 6 months showed better performance on the letter cancellation test and Digit span test, along with lower perceived stress and higher happiness scores compared with those practicing for less than 6 months (P< 0.05).</p><p><strong>Conclusion: </strong>Long-term regular yoga practice is associated with improved cognitive performance, reduced perceived stress, and enhanced psychological well-being, suggesting its potential role in promoting neurocognitive and mental health.</p>","PeriodicalId":50686,"journal":{"name":"Clinica Terapeutica","volume":"177 5","pages":"1074-1078"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148851687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Six-Month Outcomes of Ahmed Glaucoma Valve Implantation Using a Patch Graft-Free Scleral Tunnel Technique in Eyes with Refractory Glaucoma: A prospective, non-comparative interventional study.","authors":"Thi Uyen Duyen Nguyen, Kim Thanh Doan, Bao Giang Kim","doi":"10.7417/CT.2026.2095","DOIUrl":"10.7417/CT.2026.2095","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate early 6-month outcomes of Ahmed glaucoma valve implantation using a patch graft-free scleral tunnel technique in eyes with refractory glaucoma.</p><p><strong>Methods: </strong>This prospective, non-comparative interventional case series included 35 eyes of 35 patients with refractory glaucoma who underwent Ahmed FP7 valve implantation using a patch graft-free scleral tunnel technique at Ho Chi Minh City Eye Hospital from February 2025 to March 2026. Intraocular pressure (IOP), visual acuity (VA), number of glaucoma medications, and complications were assessed on postoperative day 1, week 1, month 1, month 3, and month 6.</p><p><strong>Results: </strong>Mean IOP decreased from 33.54 ± 9.28 mmHg preoperatively to 16.33 ± 5.00 mmHg at 6 months (p < 0.001), corresponding to a mean IOP reduction of 49.3%. The mean number of glaucoma medications decreased from 3.80 ± 0.41 to 1.09 ± 1.09 (p < 0.001). The overall success rate was 91.4%, including 40.0% complete success and 51.4% qualified success. No tube exposure was observed.</p><p><strong>Conclusion: </strong>Ahmed glaucoma valve implantation using a patch graft-free scleral tunnel technique provided adequate IOP control, a high 6-month success rate, and no tube exposure in this cohort. This technique may be a useful alternative when patch graft materials are unavailable.</p>","PeriodicalId":50686,"journal":{"name":"Clinica Terapeutica","volume":"177 5","pages":"987-991"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148851706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Thyroid Cancer Management in Contemporary Practice: A Systematic Review and Meta-Analysis of Diagnostic Pathways, Surgical Strategies, Airway Challenges, and Mediastinal Extension.","authors":"Ahmed Farouk Ibrahim Koraitim, Mahmoud Mostafa Mohamed, Mohammad Abd Elhameed Alwaseef, Abduallah Mawkili, Hesham A Abdesalam, Jalal H Abu Halimah, Khaled Asem Allam, Ahmed Abd Alrahman Mahmoud Ibrahim, Hossam Salah El-Sayed Ibrahim, Sherif Mohsen Mohamed Elsayed Abdelaziz, Mohamad Adel Abdalgaleel, Murad Barakat, Samantha Georgette Bukas, Abdulmabod Omar, Mohamed Adel Mobasher","doi":"10.7417/CT.2026.2130","DOIUrl":"10.7417/CT.2026.2130","url":null,"abstract":"<p><strong>Background: </strong>Thyroid cancer is the most common endocrine malignancy worldwide, with a clinically significant subset of patients presenting with locally advanced disease involving the trachea, recurrent laryngeal nerve, esophagus, and superior mediastinum. However, evidence describing the integrated burden of diagnostic limitations, airway complications, surgical outcomes, and mediastinal involvement remains fragmented across small and heterogeneous studies.</p><p><strong>Objectives: </strong>This study aimed to systematically evaluate and quantitatively synthesize evidence on diagnostic performance, perioperative airway management, surgical outcomes, and mediastinal extension in thyroid cancer, with emphasis on locally advanced and complex disease reported between January 2021 and January 2026.</p><p><strong>Methods: </strong>A systematic review and meta-analysis were conducted in accordance with PRISMA 2020 guidelines and the MOOSE framework. PubMed/MEDLINE, Scopus, Web of Science, Cochrane Library, and Embase were searched. Studies reporting surgical outcomes, airway complications, mediastinal extension, recurrent laryngeal nerve injury, and imaging diagnostic accuracy in thyroid cancer were included. Secondary systematic reviews and meta-analyses were excluded from quantitative pooling to avoid data duplication. Risk of bias was assessed using the Newcastle-Ottawa Scale and Cochrane RoB 2 tool where applicable. Random-effects meta-analyses were performed using the DerSimonian-Laird method.</p><p><strong>Results: </strong>Eleven primary studies published between 2021 and 2026, comprising 6,142 patients, were included. The pooled incidence of difficult airway was 9.4% (95% CI: 6.1-14.2%; I² = 61.3%), while overall surgical morbidity was 21.3% (95% CI: 16.8-26.5%; I² = 72.6%). Tracheal invasion was present in 28.7% (95% CI: 21.4-37.3%) of locally advanced cases. Mediastinal extension requiring thoracic surgical access occurred in 18.3% (95% CI: 12.7-25.7%) of retrosternal cases. Recurrent laryngeal nerve injury ranged from 2.8% to 5.9% (transient) and 0.5% to 1.4% (permanent) across studies. Computed tomography demonstrated a pooled sensitivity of 61.4% and specificity of 90.8% for tracheal invasion detection.</p><p><strong>Conclusion: </strong>This meta-analysis provides the most comprehensive and up-to-date quantitative synthesis of surgical complexity in thyroid cancer across diagnostic, airway, surgical, and mediastinal domains. Locally advanced disease is consistently associated with increased rates of difficult airway management, tracheal invasion, and requirement for thoracic surgical access, highlighting its substantially elevated perioperative risk profile. These findings underscore the importance of structured multidisciplinary preoperative assessment, advanced airway planning, and the routine use of intraoperative neuromonitoring in high-risk cases to optimise surgical safety and outcomes.</p>","PeriodicalId":50686,"journal":{"name":"Clinica Terapeutica","volume":"177 5","pages":"1281-1298"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148851837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic Performance of Coronary CT Angiography versus Invasive Coronary Angiography in Patients Undergoing Percutaneous Coronary Intervention: A Cross-Sectional Study.","authors":"Duc Ha Hoang, Thu Phuong Hoang, Thi Hanh Vu, Thi Phuong Linh Hoang","doi":"10.7417/CT.2026.2114","DOIUrl":"10.7417/CT.2026.2114","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to describe the diagnostic value of coronary computed tomography angiography (CCTA) compared with invasive coronary angiography (ICA) in patients with coronary artery disease.</p><p><strong>Methods: </strong>A cross-sectional descriptive study was conducted using retrospective data. Non-probability sampling was applied, including all eligible patients who met the inclusion criteria during the study period from January 2022 to December 2024 at Hai Phong International General Hospital. Study Equipment: A 128-slice CT scanner (Revolution CT, GE Healthcare, USA) and a digital subtraction angiography (DSA) system for invasive coronary angiography (Philips, Netherlands) were utilized.</p><p><strong>Results: </strong>A total of 52 patients were included, with a mean age of 71.65 ± 9.5 years. For the diagnosis of >70% stenosis of the right coronary artery (RCA), CCTA demonstrated a sensitivity of 91.3% and a specificity of 24.1% (p = 0.379). For >70% stenosis of the left anterior descending artery (LAD), CCTA showed a sensitivity of 80% and a specificity of 63.6% (p = 0.001). For >70% stenosis of the left circumflex artery (LCx), CCTA yielded a sensitivity of 20.0% and a specificity of 89.1% (p = 0.005).</p><p><strong>Conclusion: </strong>CCTA is a non-invasive technique with shorter acquisition time and lower cost compared to invasive coronary angiography. Advances in CT technology have progressively improved diagnostic performance, thereby supporting more accurate and appropriate therapeutic decision-making.</p>","PeriodicalId":50686,"journal":{"name":"Clinica Terapeutica","volume":"177 5","pages":"1131-1135"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148851939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}