Cognitive Affective & Behavioral Neuroscience最新文献

{"title":"Pre-choice midbrain fluctuations affect self-control in food choice: A functional magnetic resonance imaging (fMRI) study.","authors":"Jakub Skałbania, Łukasz Tanajewski, Marcin Furtak, Todd A Hare, Marek Wypych","doi":"10.3758/s13415-024-01231-7","DOIUrl":"10.3758/s13415-024-01231-7","url":null,"abstract":"<p><p>Recent studies have shown that spontaneous pre-stimulus fluctuations in brain activity affect higher-order cognitive processes, including risky decision-making, cognitive flexibility, and aesthetic judgments. However, there is currently no direct evidence to suggest that pre-choice activity influences value-based decisions that require self-control. We examined the impact of fluctuations in pre-choice activity in key regions of the reward system on self-control in food choice. In the functional magnetic resonance imaging (fMRI) scanner, 49 participants made 120 food choices that required self-control in high and low working memory load conditions. The task was designed to ensure that participants were cognitively engaged and not thinking about upcoming choices. We defined self-control success as choosing a food item that was healthier over one that was tastier. The brain regions of interest (ROIs) were the ventral tegmental area (VTA), putamen, nucleus accumbens (NAc), and caudate nucleus. For each participant and condition, we calculated the mean activity in the 3-s interval preceding the presentation of food stimuli in successful and failed self-control trials. These activities were then used as predictors of self-control success in a fixed-effects logistic regression model. The results indicate that increased pre-choice VTA activity was linked to a higher probability of self-control success in a subsequent food-choice task within the low-load condition, but not in the high-load condition. We posit that pre-choice fluctuations in VTA activity change the reference point for immediate (taste) reward evaluation, which may explain our finding. This suggests that the neural context of decisions may be a key factor influencing human behavior.</p>","PeriodicalId":50672,"journal":{"name":"Cognitive Affective & Behavioral Neuroscience","volume":" ","pages":"387-401"},"PeriodicalIF":2.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11906498/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142394952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Social network size, empathy, and white matter: A diffusion tensor imaging (DTI) study.","authors":"Apoorva Veerareddy, Huihua Fang, Nooshin Safari, Pengfei Xu, Frank Krueger","doi":"10.3758/s13415-024-01225-5","DOIUrl":"10.3758/s13415-024-01225-5","url":null,"abstract":"<p><p>Social networks are fundamental for social interactions, with the social brain hypothesis positing that the size of the neocortex evolved to meet social demands. However, the role of fractional anisotropy (FA) in white matter (WM) tracts relevant to mentalizing, empathy, and social networks remains unclear. In this study, we investigated the relationships between FA in brain regions associated with social cognition (superior longitudinal fasciculus (SLF), cingulum (CING), uncinate fasciculus, inferior fronto-occipital fasciculus), social network characteristics (diversity, size, complexity), and empathy (cognitive, affective). We employed diffusion tensor imaging, tract-based spatial statistics, and mediation analyses to examine these associations. Our findings revealed that increased social network size was positively correlated with FA in the left SLF. Further, our mediation analysis showed that lower FA in left CING was associated with increased social network size, mediated by cognitive empathy. In summary, our findings suggest that WM tracts involved in social cognition play distinct roles in social network size and empathy, potentially implicating affective brain regions. In conclusion, our findings offer new perspectives on the cognitive mechanisms involved in understanding others' mental states and experiencing empathy within supportive social networks, with potential implications for understanding individual differences in social behavior and mental health.</p>","PeriodicalId":50672,"journal":{"name":"Cognitive Affective & Behavioral Neuroscience","volume":" ","pages":"471-487"},"PeriodicalIF":2.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142362457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"How interoceptive sensibility moderates decision-making: an fMRI study of neuroforecasting mobile games engagement.","authors":"Ying-Chun Chen, Yun-Hsin Huang, Pai-He Hsiao, Nai-Shing Yen","doi":"10.3758/s13415-024-01238-0","DOIUrl":"10.3758/s13415-024-01238-0","url":null,"abstract":"<p><p>Neuroscientists in decision science have advanced an affect-integration-motivation (AIM) framework, demonstrating that neural activity associated with positive affect or value integration can predict individual and aggregate choice. Given that individuals with higher interoceptive sensibility (IS) have tendency to engage their bodily sensations and thus exhibit a more coherent pattern between their neural, affective, and behavioral measures, we investigated how IS may interact with the affective/integrative components for predicting individual and aggregate choice. Thus, we 1) explored neural underpinnings of individual choice, affective ratings, aggregate outcomes, 2) examined how the above-mentioned measures predict individual and aggregate choices on mobile games, and 3) tested the moderation effect of IS by comparing the differences in how these measures perform in prediction models between subgroups of IS. Neuroimaging results showed that individual choice associated with NAcc activity, aggregate download rate tracked by regions in salience network, and revenue additionally tracked by regions in motor tendency and attention regulation. Affective ratings and AIns activity predicted individual download choice; mPFC activity forecasted aggregate download rate, and positive arousal forecasted aggregate revenue. As hypothesized, the high IS group displayed coherent correlations between affective ratings, individual choice, and neural measures. More importantly, at the aggregate level, mPFC activity (integrative component), forecasted aggregate download rate above and beyond ratings and individual choice in the high IS group, with this prediction significantly stronger compared with the low IS group. These findings extend the AIM framework by shedding light on the influence of interoceptive sensibility on the neurobehavioral mechanisms underlying human decision-making.</p>","PeriodicalId":50672,"journal":{"name":"Cognitive Affective & Behavioral Neuroscience","volume":" ","pages":"415-433"},"PeriodicalIF":2.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142802989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Low emotional contagious behavior induces PTSD susceptibility in observers and is related to the regulation of oxytocin receptor in mice.","authors":"Yang Liu, Yuan Gao, Zhidong Ma, Qingge Zhang, Ruiqiang Sun, Ling Wang, Sishun Zhao, Changjiang Li, Bo Lian, Hongwei Sun, Lin Sun","doi":"10.3758/s13415-024-01244-2","DOIUrl":"10.3758/s13415-024-01244-2","url":null,"abstract":"<p><strong>Background: </strong>Post-traumatic stress disorder (PTSD) is a serious psychiatric disorder that occurs after an individual has witnessed or experienced a major traumatic event. Emotional contagion seems to play an important role in witnessing trauma, highlighting the importance of understanding the neurobiological consequences of psychological or emotional stress and its impact on the individual's mental health. Therefore, understanding the relationship between emotional contagion and PTSD susceptibility and the abnormal neurobiological and behavioral changes behind it could help find effective molecular treatment targets.</p><p><strong>Methods: </strong>The formalin pain test was used to distinguish the level of emotional contagion in observer mice, dividing them into quartiles according to their pain response. The upper and lower quartiles were the emotional contagion-prone (ECP) and -resistant (ECR) groups, respectively. The vicarious social defeat stress (VSDS) procedure was used to establish PTSD models in mice with various emotional contagion levels when witnessing stress. Open field, elevated plus maze, social interaction test, and forced swimming test were used to examine PTSD-like symptoms. Changes in the medial prefrontal cortex (mPFC) mRNA expression of brain-derived neurotrophic factor (BDNF) and oxytocin receptor (OTR) were detected by qPCR, and their protein levels were analyzed by Western blot and immunofluorescence staining.</p><p><strong>Results: </strong>The formalin pain test induced emotional contagion behaviors in mice between the ECP and ECR levels. The VSDS procedure resulted in PTSD symptoms in mice; mice in the lowest quartile were characterized by high levels of anxiety, depression, and social avoidance behaviors, such as decreased autonomous activity and residence time in the open field test or open arms position and increased immobility time and social avoidance behavior. These were accompanied by reduced OTR and BDNF protein expression levels and fluorescence intensity, as well as reduced OTR and BDNF mRNA levels in the mPFC.</p><p><strong>Conclusions: </strong>Emotional contagion can induce PTSD-like behavior in mice that witnessed stress. Low emotional contagion behavior increased PTSD susceptibility in the observer mice and might be related to the regulation of their oxytocin receptors.</p>","PeriodicalId":50672,"journal":{"name":"Cognitive Affective & Behavioral Neuroscience","volume":" ","pages":"515-530"},"PeriodicalIF":2.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143025561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neural dynamics underlying coordination between training-induced habitual and goal-directed responses.","authors":"Mengyang He, Wen Wen, Douglas Hazel, Peyton Berning","doi":"10.3758/s13415-024-01242-4","DOIUrl":"10.3758/s13415-024-01242-4","url":null,"abstract":"<p><p>Understanding the neurocognitive mechanisms that govern the coordination of habitual and goal-directed behaviors is important, because impaired coordination will cause various behavioral disorders. However, inducing habitual responses in human beings through repetitive stimuli-response training in a laboratory setting is a challenge. Well-trained sports athletes, who have automatic perception-action associations toward expertise-related stimuli, provide a natural sample to address this critical knowledge gap. We recorded electroencephalograms (EEG) of well-trained sports athletes while they performed a Simon task with expertise-related stimuli. By manipulating the congruency between the location of expertise-related stimuli and the response hand, we dissociated automatic habitual response and goal-directed inhibition control. We observed a stronger behavioral congruency effect on expertise-related stimuli than neutral stimuli in sports athletes but not healthy controls. Furthermore, sports athletes exhibited larger response-locked lateralized readiness potentials and stronger frontocentral beta band (15-25 Hz) activity in the congruent condition than the incongruent condition, which indicate an enhanced response tendency toward expertise-related stimuli. In contrast, prominent mid-frontal theta (3-7 Hz) activity observed in the incongruent condition signaled the involvement of response inhibition. Additionally, lateralized readiness potentials amplitude and theta power showed significant correlation with performance efficiency. Taken together, these results suggest that sports athletes exhibit an enhanced coordination for expertise-related stimuli, involving automatic response preparation and proficient response inhibition through extensive training.</p>","PeriodicalId":50672,"journal":{"name":"Cognitive Affective & Behavioral Neuroscience","volume":" ","pages":"344-357"},"PeriodicalIF":2.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142787618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Brain activity associated with emotion regulation predicts individual differences in working memory ability.","authors":"Scarlett B Horner, Roshni Lulla, Helen Wu, Shruti Shaktivel, Anthony Vaccaro, Ellen Herschel, Leonardo Christov-Moore, Colin McDaniel, Jonas T Kaplan, Steven G Greening","doi":"10.3758/s13415-024-01232-6","DOIUrl":"10.3758/s13415-024-01232-6","url":null,"abstract":"<p><p>Previous behavioral research has found that working memory is associated with emotion regulation efficacy. However, there has been mixed evidence as to whether the neural mechanisms between emotion regulation and working memory overlap. The present study tested the prediction that individual differences on the working memory subtest of the Weschler Adult Intelligence Scale (WAIS-IV) could be predicted from the pattern of brain activity produced during emotion regulation in regions typically associated with working memory, such as the dorsal lateral prefrontal cortex (dlPFC). A total of 101 participants completed an emotion regulation fMRI task in which they either viewed or reappraised negative images. Participants also completed working memory test outside the scanner. A whole brain covariate analysis contrasting the reappraise negative and view negative BOLD response found that activity in the right dlPFC positively related to working memory ability. Moreover, a multivoxel pattern analysis approach using tenfold cross-validated support vector regression in regions-of-interest associated with working memory, including bilateral dlPFC, demonstrated that we could predict individual differences in working memory ability from the pattern of activity associated with emotion regulation. These findings support the idea that emotion regulation shares underlying cognitive processes and neural mechanisms with working memory, particularly in the dlPFC.</p>","PeriodicalId":50672,"journal":{"name":"Cognitive Affective & Behavioral Neuroscience","volume":" ","pages":"329-343"},"PeriodicalIF":2.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142394950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Implementations of sign- and goal-tracking behavior in humans: A scoping review.","authors":"Michelle Heck, Nancy Durieux, Patrick Anselme, Etienne Quertemont","doi":"10.3758/s13415-024-01230-8","DOIUrl":"10.3758/s13415-024-01230-8","url":null,"abstract":"<p><p>Animal research has identified two major phenotypes in the tendency to attribute incentive salience to a reward-associated cue. Individuals called \"sign-trackers\" (STs) preferentially approach the cue, assigning both predictive and incentive values to it. In contrast, individuals called \"goal-trackers\" (GTs) preferentially approach the location of the upcoming reward, assigning only a predictive value to the cue. The ST/GT model has been shown to be relevant to understanding addiction vulnerability and other pathological behaviors in animals. Therefore, recent studies tried to implement this animal model in the human population. This scoping review aimed to identify and map evidence of human sign- and goal-tracking. Studies that explicitly measured human sign- and goal-tracking or related phenomena (e.g., attentional bias induced by reward-related cues), using paradigms in line with the animal model, were eligible for this review. We searched for published, unpublished, and gray literature (PhD theses, posters, conference papers) through the following databases: MEDLINE, Scopus, PsycINFO, Embase, OSF, and Google Scholar. The JBI scoping review methodology was adopted. Screening and extraction were carried out by three reviewers, in pairs. A total of 48 studies were identified. These studies used various experimental paradigms and used the term \"sign-tracking\" inconsistently, sometimes implicitly or not at all. We conclude that the literature on human sign-tracking is very heterogeneous on many levels. Overall, evidence supports the existence of sign- and goal-tracking behaviors in humans, although further validated research is crucially needed.</p>","PeriodicalId":50672,"journal":{"name":"Cognitive Affective & Behavioral Neuroscience","volume":" ","pages":"263-290"},"PeriodicalIF":2.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142577119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Caregiver or Playmate? Fathers' and mothers' brain responses to ball-play with children.","authors":"Dorukhan Açıl, Lara M C Puhlmann, Lars O White, Pascal Vrticka","doi":"10.3758/s13415-024-01237-1","DOIUrl":"10.3758/s13415-024-01237-1","url":null,"abstract":"<p><p>Parents and children often engage in joint play-a domain where mothers and fathers are thought to exhibit disparate behaviors and impact child development via distinct mechanisms. However, little is known about the neural substrates of mother-child and father-child play. In this fMRI study, we sampled the brain activation of parents of preschoolers (N = 88) during a novel event-related adaptation of the virtual ball-tossing game \"Cyberball.\" Mothers (N = 40) and fathers (N = 48) played \"Cyberball\" ostensibly with their own and an unrelated child, who consecutively included, excluded, and reincluded parents. We found that overall, exclusion yielded comparable neural activations in mothers and fathers associated with mentalizing, saliency, and emotion processing. We also observed a parent gender effect in several brain areas. While mothers exhibited increased reward- and attention-related activity during inclusion, fathers displayed increased mentalizing-related activity during exclusion. Furthermore, we tested parents' response to reinclusion, which revealed a selective decrease in reward-related activity. Finally, exploratory analyses showed that parental involvement was positively correlated with parental brain activity within attention- and mentalizing-related areas during inclusion, as opposed to other game phases, and that an anxious parenting style was associated with increased neural sensitivity for game events involving their own child. Overall, our study elucidates the common and distinct neural networks that mothers and fathers engage during play interactions with their children, supporting theories that postulate only a partial differentiation of paternal and maternal parenting systems.</p>","PeriodicalId":50672,"journal":{"name":"Cognitive Affective & Behavioral Neuroscience","volume":" ","pages":"434-453"},"PeriodicalIF":2.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11906569/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142787607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Empathy and moral judgment: Systematic review and meta-analysis of ERP studies.","authors":"Youran Zhang, Zhiqiang Yan, Yiyi Wang, Yanjie Su","doi":"10.3758/s13415-025-01287-z","DOIUrl":"https://doi.org/10.3758/s13415-025-01287-z","url":null,"abstract":"<p><p>Although the bidirectional relationship between empathy and moral judgment has been extensively investigated, the underlying neural mechanisms remain elusive. The current study examined 19 event-related potential studies to explore the relationship between empathy and moral judgment, including 60 effect sizes. It was found that individuals with higher levels of empathy exhibited a significantly increased amplitude in the N2 component during moral judgment tasks when presented with moral versus immoral scenarios (r_N2 = 0.18, 95% confidence interval (CI) [0.04, 0.31], p = 0.010). However, the empathy response toward the target person is also influenced by the moral characteristics of the individual, as evidenced by the enhanced amplitude of P3 and LPP components in the empathic response toward high-moral individuals (r_P3 = 0.30, 95% CI [0.16, 0.42], p < 0.001; r_LPP = 0.16, 95% CI [0.04, 0.28], p = 0.011). These results suggest that the effect of empathy on moral judgment involves early attention allocation, while the influence of moral judgment on empathy likely involves top-down cognitive regulation. The findings of the present study reveal distinct neural processes between empathy and moral judgment, extending dual-process theories and aiding in developing programs for moral behavior and empathy intervention.</p>","PeriodicalId":50672,"journal":{"name":"Cognitive Affective & Behavioral Neuroscience","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143765693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anhedonia relates to reduced striatal reward anticipation in depression but not in schizophrenia or bipolar disorder: A transdiagnostic study.","authors":"Anna Daniels, Sarah A Wellan, Anne Beck, Susanne Erk, Carolin Wackerhagen, Nina Romanczuk-Seiferth, Kristina Schwarz, Janina I Schweiger, Andreas Meyer-Lindenberg, Andreas Heinz, Henrik Walter","doi":"10.3758/s13415-024-01261-1","DOIUrl":"10.3758/s13415-024-01261-1","url":null,"abstract":"<p><p>Anhedonia, i.e., the loss of pleasure or lack of reactivity to reward, is a core symptom of major psychiatric conditions. Altered reward processing in the striatum has been observed across mood and psychotic disorders, but whether anhedonia transdiagnostically contributes to these deficits remains unclear. We investigated associations between self-reported anhedonia and neural activation during reward anticipation and consumption across patients with schizophrenia (SZ), bipolar disorder (BD), major depressive disorder (MD), and healthy controls (HC). Using the Monetary Incentive Delay paradigm, we acquired functional magnetic resonance imaging data sets in 227 participants (18-65 years), including patients with SZ (n = 44), BD (n = 47), MD (n = 56), and HC (n = 80). To capture anhedonia, three items of the Symptom Checklist-90-R were entered into exploratory factor analysis, which resulted in a single anhedonia factor. Associations between anhedonia and neural activation were assessed within a striatal region-of-interest and exploratorily across the whole brain (p_FWE < .05). Self-reported anhedonia was high in MD, low in HC, and intermediate in SZ and BD. During reward anticipation, anhedonia correlated with reduced striatal activation; however, the correlation depended on diagnostic group. Specifically, the effect was driven by a negative relationship between anhedonia and dorsal striatal (putamen) activity within the MD group; for reward consumption, no correlations were found. Our results indicate that anticipatory anhedonia in MD may relate to reduced behavioral motivation via disrupted encoding of motor plans in the dorsal striatum. Future transdiagnostic research should stratify participants by anhedonia levels to achieve more homogeneous samples in terms of underlying neurobiology.</p>","PeriodicalId":50672,"journal":{"name":"Cognitive Affective & Behavioral Neuroscience","volume":" ","pages":"501-514"},"PeriodicalIF":2.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11906564/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143069389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}