Cognitive and Behavioral Neurology最新文献_第5页

Predictive Ability of Frontal Assessment Battery for Cognitive Improvement After Shunt Surgery in Individuals With Idiopathic Normal Pressure Hydrocephalus. 额叶评估电池对特发性常压脑积水患者分流术后认知改善的预测能力。

IF 1.3 4区医学

Cognitive and Behavioral Neurology Pub Date : 2023-12-01 DOI: 10.1097/WNN.0000000000000350

Yuki Asahara, Machiko Suda, Shusaku Omoto, Kazushige Kobayashi, Masamichi Atsuchi, Hiroyasu Nagashima, Masahiko Suzuki

{"title":"Predictive Ability of Frontal Assessment Battery for Cognitive Improvement After Shunt Surgery in Individuals With Idiopathic Normal Pressure Hydrocephalus.","authors":"Yuki Asahara, Machiko Suda, Shusaku Omoto, Kazushige Kobayashi, Masamichi Atsuchi, Hiroyasu Nagashima, Masahiko Suzuki","doi":"10.1097/WNN.0000000000000350","DOIUrl":"10.1097/WNN.0000000000000350","url":null,"abstract":"Background: The predictive ability of the Frontal Assessment Battery (FAB) for postoperative cognitive improvement in idiopathic normal pressure hydrocephalus (iNPH) is unstudied.Objective: To compare the predictive ability of the FAB and the Mini-Mental State Examination (MMSE) for postoperative cognitive improvement in individuals with iNPH after shunt surgery.Method: We retrospectively reviewed the medical records of individuals with iNPH who had shunt surgery between January 2016 and October 2018. Individuals had completed the tap test and clinical evaluations (FAB, MMSE, Timed Up and Go [TUG]) both before and 24-48 hours after CSF tapping and after surgery. We excluded individuals without complete clinical evaluations and those with shunt surgery performed >6 months after CSF tapping. Factors associated with postoperative FAB and MMSE improvement as per the 2011 iNPH guidelines were extracted using univariate and multivariate logistic regression analyses. Independent variables were baseline FAB and MMSE scores, FAB and MMSE score changes and TUG amelioration rate after CSF tapping, Evans index, age, and days from CSF tapping to surgery and from surgery to postoperative assessment.Results: The mean number of days from CSF tapping to surgery and from surgery to postoperative assessment were 77.5 (SD = 36.0) and 42.0 (SD = 14.5), respectively. Logistic regression analyses showed significant associations in the univariate analyses of postoperative FAB improvement with baseline FAB scores ( P = 0.043) and with FAB score changes after CSF tapping ( P = 0.047).Conclusion: The FAB may help predict postoperative cognitive improvement after shunt surgery better than the MMSE.","PeriodicalId":50671,"journal":{"name":"Cognitive and Behavioral Neurology","volume":" ","pages":"228-236"},"PeriodicalIF":1.3,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9920823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development of a Speech-based Composite Score for Remotely Quantifying Language Changes in Frontotemporal Dementia. 开发一种基于语音的复合评分，用于远程量化额颞叶痴呆患者的语言变化。

IF 1.3 4区医学

Cognitive and Behavioral Neurology Pub Date : 2023-12-01 DOI: 10.1097/WNN.0000000000000356

Jessica Robin, Mengdan Xu, Liam D Kaufman, William Simpson, Stella McCaughey, Nadine Tatton, Charles Wolfus, Michael Ward

{"title":"Development of a Speech-based Composite Score for Remotely Quantifying Language Changes in Frontotemporal Dementia.","authors":"Jessica Robin, Mengdan Xu, Liam D Kaufman, William Simpson, Stella McCaughey, Nadine Tatton, Charles Wolfus, Michael Ward","doi":"10.1097/WNN.0000000000000356","DOIUrl":"10.1097/WNN.0000000000000356","url":null,"abstract":"Background: Changes to speech and language are common symptoms across different subtypes of frontotemporal dementia (FTD). These changes affect the ability to communicate, impacting everyday functions. Accurately assessing these changes may help clinicians to track disease progression and detect response to treatment.Objective: To determine which aspects of speech show significant change over time and to develop a novel composite score for tracking speech and language decline in individuals with FTD.Method: We recruited individuals with FTD to complete remote digital speech assessments based on a picture description task. Speech samples were analyzed to derive acoustic and linguistic measures of speech and language, which were tested for longitudinal change over the course of the study and were used to compute a novel composite score.Results: Thirty-six (16 F, 20 M; M age = 61.3 years) individuals were enrolled in the study, with 27 completing a follow-up assessment 12 months later. We identified eight variables reflecting different aspects of language that showed longitudinal decline in the FTD clinical syndrome subtypes and developed a novel composite score based on these variables. The resulting composite score demonstrated a significant effect of change over time, high test-retest reliability, and a correlation with standard scores on various other speech tasks.Conclusion: Remote digital speech assessments have the potential to characterize speech and language abilities in individuals with FTD, reducing the burden of clinical assessments while providing a novel measure of speech and language abilities that is sensitive to disease and relevant to everyday function.","PeriodicalId":50671,"journal":{"name":"Cognitive and Behavioral Neurology","volume":" ","pages":"237-248"},"PeriodicalIF":1.3,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10683975/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50163518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Why We Forget and How to Remember Better: The Science Behind Memory. 为什么我们会忘记以及如何更好地记住：记忆背后的科学。

IF 1.3 4区医学

Cognitive and Behavioral Neurology Pub Date : 2023-12-01 DOI: 10.1097/WNN.0000000000000351

Howard S Kirshner

引用次数: 0

Development of Self-made Gestures as an Adaptive Strategy for Communication in an Individual With Childhood Apraxia of Speech. 在儿童言语失调症个体中，发展自制手势作为一种适应性沟通策略。

IF 1.3 4区医学

Cognitive and Behavioral Neurology Pub Date : 2023-12-01 DOI: 10.1097/WNN.0000000000000354

Michitaka Funayama, Asuka Nakajima

{"title":"Development of Self-made Gestures as an Adaptive Strategy for Communication in an Individual With Childhood Apraxia of Speech.","authors":"Michitaka Funayama, Asuka Nakajima","doi":"10.1097/WNN.0000000000000354","DOIUrl":"10.1097/WNN.0000000000000354","url":null,"abstract":"Individuals with childhood apraxia of speech often exhibit greater difficulty with expressive language than with receptive language. As a result, they may benefit from alternative modes of communication. Here, we present a patient with childhood apraxia of speech who used pointing as a means of communication at age 2 ¼ years and self-made gestures at age 3½, when he had severe difficulties speaking in spite of probable normal comprehension abilities. His original gestures included not only word-level expressions, but also sentence-length ones. For example, when expressing \"I am going to bed,\" he pointed his index finger at himself (meaning I ) and then put both his hands together near his ear ( sleep ). When trying to convey the meaning of \"I enjoyed the meal and am leaving,\" he covered his mouth with his right hand ( delicious ), then joined both of his hands in front of himself ( finish ) and finally waved his hands ( goodbye ). These original gestures and pointing peaked at the age of 4 and then subsided and completely disappeared by the age of 7, when he was able to make himself understood to some extent with spoken words. The present case demonstrates an adaptive strategy for communication that might be an inherent competence for human beings.","PeriodicalId":50671,"journal":{"name":"Cognitive and Behavioral Neurology","volume":" ","pages":"249-258"},"PeriodicalIF":1.3,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41151570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Aranzio's Seahorse and the Search for Memory and Consciousness. 阿兰齐奥的海马和对记忆和意识的探索。

IF 1.4 4区医学

Cognitive and Behavioral Neurology Pub Date : 2023-12-01 DOI: 10.1097/WNN.0000000000000352

Howard S Kirshner

引用次数: 0

Physical Exercise and Serum BDNF Levels: Accounting for the Val66Met Polymorphism in Older Adults. 体育锻炼和血清BDNF水平:老年人Val66Met多态性的解释

IF 1.3 4区医学

Cognitive and Behavioral Neurology Pub Date : 2023-12-01 DOI: 10.1097/WNN.0000000000000349

Oda Bugge Kambestad, Kristine Sirevåg, Jelena Mrdalj, Anders Hovland, Trygve Bruun Endal, Eva Andersson, Trond Sjøbø, Silje Haukenes Stavestrand

{"title":"Physical Exercise and Serum BDNF Levels: Accounting for the Val66Met Polymorphism in Older Adults.","authors":"Oda Bugge Kambestad, Kristine Sirevåg, Jelena Mrdalj, Anders Hovland, Trygve Bruun Endal, Eva Andersson, Trond Sjøbø, Silje Haukenes Stavestrand","doi":"10.1097/WNN.0000000000000349","DOIUrl":"10.1097/WNN.0000000000000349","url":null,"abstract":"Background: Brain-derived neurotrophic factor (BDNF) expression, which can be measured in blood serum, has been found to increase with aerobic exercise. The link between BDNF level, physical exercise, and genetic status (Val66Met polymorphism) has not been well researched in older adults.Objective: To investigate the possible link between BDNF expression, acute aerobic exercise, and the Val66Met polymorphism in older adults.Method: Twenty-three healthy older adults participated in one session of acute aerobic exercise. Their serum BDNF levels were measured both at baseline and post exercise. Saliva samples were collected to identify each individual's genetic status.Results: At baseline, the individuals' mean serum BDNF level was 16.03 ng/mL (Val66Val = 15.89 ng/mL; Val66Met = 16.34 ng/mL); post exercise, the individuals' mean serum BDNF level was 16.81 ng/mL (Val66Val = 16.14 ng/mL; Val66Met = 18.34 ng/mL).Conclusion: One session of acute aerobic exercise significantly increased the individuals' mean serum BDNF level. Males had higher BDNF levels than females. There was a significant interaction between gender and BDNF expression post exercise and a significant between-group effect of gender. The Val66Met carriers had a more positive response to the acute aerobic exercise compared with the Val66Val carriers, although without a significant difference between the two groups.","PeriodicalId":50671,"journal":{"name":"Cognitive and Behavioral Neurology","volume":" ","pages":"219-227"},"PeriodicalIF":1.3,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10683974/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9751348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Toward a Unified Classification System for Brain-Mind Disorders: Putting Calls for Integrated Clinical Neuroscience Into Action. 建立大脑心智障碍的统一分类系统：将整合临床神经科学的呼吁付诸行动。

IF 1.3 4区医学

Cognitive and Behavioral Neurology Pub Date : 2023-12-01 DOI: 10.1097/WNN.0000000000000353

Michael P H Stanley, David A Silbersweig, David L Perez

{"title":"Toward a Unified Classification System for Brain-Mind Disorders: Putting Calls for Integrated Clinical Neuroscience Into Action.","authors":"Michael P H Stanley, David A Silbersweig, David L Perez","doi":"10.1097/WNN.0000000000000353","DOIUrl":"10.1097/WNN.0000000000000353","url":null,"abstract":"Dividing the brain-mind into the specialized fields of neurology and psychiatry has produced many granular advantages, but these silos have imposed barriers to comprehensively understanding and contextualizing the fundamentals governing mental life and its maladies. Scientific inquiry into these fundamentals cannot reach its full potential without interdigitating the boundaries of two specialties of the same organ for both scholarship and clinical practice. We propose that to truly integrate disorders of the brain and the mind for research and clinical care, we must carefully reexamine the classification of its disorders (nosology) as an instrument to develop a coherent pathological and psychological framework. We call on professional organizations from neurology, psychiatry, behavioral neurology, neuropsychiatry, neuropsychology, and other relevant subspecialties (eg, geriatric psychiatry) to convene a multidisciplinary task force to define the current classification principles of their subspecialties and work toward developing an integrated nosology. The effect of a shared classification system, which we acknowledge is a difficult proposition philosophically and politically, would have transformative potential across educational, clinical, scientific, programmatic, and sociocultural realms. If accomplished, this initiative would provide a definitive step toward reducing stigma (and promoting reimbursement parity) for the full spectrum of complex brain disorders (regardless of traditional neurologic vs psychiatric conceptualizations).","PeriodicalId":50671,"journal":{"name":"Cognitive and Behavioral Neurology","volume":" ","pages":"199-201"},"PeriodicalIF":1.3,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41137888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Why We Forget and How to Remember Better: The Science Behind Memory. 为什么我们会忘记以及如何更好地记住:记忆背后的科学。

IF 1.4 4区医学

Cognitive and Behavioral Neurology Pub Date : 2023-12-01 DOI: 10.1097/WNN.0000000000000351

Howard S Kirshner

引用次数: 0

Aranzio's Seahorse and the Search for Memory and Consciousness. 阿兰齐奥的海马和对记忆和意识的探索。

IF 1.3 4区医学

Cognitive and Behavioral Neurology Pub Date : 2023-12-01 DOI: 10.1097/WNN.0000000000000352

Howard S Kirshner

引用次数: 0

A History of Present Illness. 现病史。