Cognitive and Behavioral Neurology最新文献_第2页

Promoting Growth in Behavioral Neurology: A Path Forward. 促进行为神经学的发展：前进之路。

IF 1.4 4区医学

Cognitive and Behavioral Neurology Pub Date : 2024-06-01 DOI: 10.1097/WNN.0000000000000368

James R Bateman, Sylvia Josephy-Hernandez, Liana G Apostolova, Sheldon Benjamin, A M Barrett, Bradley F Boeve, Andrew E Budson, Zeina Chemali, Chi-Ying R Lin, Kirk R Daffner, Michael D Geschwind, Kenneth M Heilman, Argye E Hillis, Samantha K Holden, Michael S Jaffee, Isaiah Kletenik, Marissa Natelson Love, Lauren R Moo, Victoria S Pelak, Daniel Z Press, Liliana Ramirez-Gomez, Howie J Rosen, Jeremy D Schmahmann, Sanjeev N Vaishnavi, Charles C Windon, Roy H Hamilton, David L Perez

{"title":"Promoting Growth in Behavioral Neurology: A Path Forward.","authors":"James R Bateman, Sylvia Josephy-Hernandez, Liana G Apostolova, Sheldon Benjamin, A M Barrett, Bradley F Boeve, Andrew E Budson, Zeina Chemali, Chi-Ying R Lin, Kirk R Daffner, Michael D Geschwind, Kenneth M Heilman, Argye E Hillis, Samantha K Holden, Michael S Jaffee, Isaiah Kletenik, Marissa Natelson Love, Lauren R Moo, Victoria S Pelak, Daniel Z Press, Liliana Ramirez-Gomez, Howie J Rosen, Jeremy D Schmahmann, Sanjeev N Vaishnavi, Charles C Windon, Roy H Hamilton, David L Perez","doi":"10.1097/WNN.0000000000000368","DOIUrl":"10.1097/WNN.0000000000000368","url":null,"abstract":"Behavioral neurology & neuropsychiatry (BNNP) is a field that seeks to understand brain-behavior relationships, including fundamental brain organization principles and the many ways that brain structures and connectivity can be disrupted, leading to abnormalities of behavior, cognition, emotion, perception, and social cognition. In North America, BNNP has existed as an integrated subspecialty through the United Council for Neurologic Subspecialties since 2006. Nonetheless, the number of behavioral neurologists across academic medical centers and community settings is not keeping pace with increasing clinical and research demand. In this commentary, we provide a brief history of BNNP followed by an outline of the current challenges and opportunities for BNNP from the behavioral neurologist's perspective across clinical, research, and educational spheres. We provide a practical guide for promoting BNNP and addressing the shortage of behavioral neurologists to facilitate the continued growth and development of the subspecialty. We also urge a greater commitment to recruit trainees from diverse backgrounds so as to dismantle persistent obstacles that hinder inclusivity in BNNP-efforts that will further enhance the growth and impact of the subspecialty. With rapidly expanding diagnostic and therapeutic approaches across a range of conditions at the intersection of neurology and psychiatry, BNNP is well positioned to attract new trainees and expand its reach across clinical, research, and educational activities.","PeriodicalId":50671,"journal":{"name":"Cognitive and Behavioral Neurology","volume":" ","pages":"49-56"},"PeriodicalIF":1.4,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140877847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Investigating the Link Between Subjective Depth Perception Deficits and Objective Stereoscopic Vision Deficits in Individuals With Acquired Brain Injury. 研究后天性脑损伤患者主观深度知觉缺陷与客观立体视觉缺陷之间的联系。

IF 1.3 4区医学

Cognitive and Behavioral Neurology Pub Date : 2024-06-01 DOI: 10.1097/WNN.0000000000000369

Michitaka Funayama, Tomohito Hojo, Yoshitaka Nakagawa, Shin Kurose, Akihiro Koreki

{"title":"Investigating the Link Between Subjective Depth Perception Deficits and Objective Stereoscopic Vision Deficits in Individuals With Acquired Brain Injury.","authors":"Michitaka Funayama, Tomohito Hojo, Yoshitaka Nakagawa, Shin Kurose, Akihiro Koreki","doi":"10.1097/WNN.0000000000000369","DOIUrl":"10.1097/WNN.0000000000000369","url":null,"abstract":"Individuals with acquired brain injury have reported subjective complaints of depth perception deficits, but few have undergone objective assessments to confirm these deficits. As a result, the literature currently lacks reports detailing the correlation between subjective depth perception deficits and objective stereoscopic vision deficits in individuals with acquired brain injury, particularly those cases that are characterized by a clearly defined lesion. To investigate this relationship, we recruited three individuals with acquired brain injury who experienced depth perception deficits and related difficulties in their daily lives. We had them take neurologic, ophthalmological, and neuropsychological examinations. We also had them take two types of stereoscopic vision tests: a Howard-Dolman-type stereoscopic vision test and the Topcon New Objective Stereo Test. Then, we compared the results with those of two control groups: a group with damage to the right hemisphere of the brain and a group of healthy controls. Performance on the two stereoscopic vision tests was severely impaired in the three patients. One of the patients also presented with cerebral diplopia. We identified the potential neural basis of these deficits in the cuneus and the posterior section of the superior parietal lobule, which play a role in vergence fusion and are located in the caudal region of the dorso-dorsal visual pathway, which is known to be crucial not only for visual spatial perception, but also for reaching, grasping, and making hand postures in the further course of that pathway.","PeriodicalId":50671,"journal":{"name":"Cognitive and Behavioral Neurology","volume":" ","pages":"82-95"},"PeriodicalIF":1.3,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140872466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Pilot Study of the Convergent and Discriminant Validity of the Dutch Version of the Parametric Go/No-Go Task. 荷兰语版 "去/不去 "参数任务的收敛性和区分性试点研究。

IF 1.4 4区医学

Cognitive and Behavioral Neurology Pub Date : 2024-06-01 DOI: 10.1097/WNN.0000000000000363

Joan E van Horn, Anna van der Schoot, Julia Wilpert, Hessel J Engelbregt, Nico Brand

{"title":"A Pilot Study of the Convergent and Discriminant Validity of the Dutch Version of the Parametric Go/No-Go Task.","authors":"Joan E van Horn, Anna van der Schoot, Julia Wilpert, Hessel J Engelbregt, Nico Brand","doi":"10.1097/WNN.0000000000000363","DOIUrl":"10.1097/WNN.0000000000000363","url":null,"abstract":"Background: The parametric go/no-go (PGNG) task is a computerized task that is designed to measure cognitive flexibility, response inhibition, and working memory. The PGNG task has been shown to measure core executive functions (EFs) in a psychometrically sound, brief, and ecologically valid manner.Objective: To analyze the psychometric properties of the Dutch version of the PGNG task in a convenience sample of nonclinical adults.Method: The sample consisted of 74 highly educated adults, with an average age of 36 years. Forty-two participants completed test battery A to investigate the task's convergent validity; 36 participants completed test battery B to investigate the task's discriminant validity. The results were analyzed using a repeated-measures ANOVA, Friedman's test, paired-samples t test, and correlation analyses.Results: Level 3 of the PGNG task places increased demands on sustained attention, response inhibition, and set-shifting. Several moderate correlations between level 3 and a complex EFs measure supported the convergent validity of this level of the PGNG task. The convergent validity of levels 1 and 2 was not supported. No significant correlations were found between PGNG levels and non-EF tests, supporting discriminant validity.Conclusion: Our study included a rather homogenous sample of highly educated participants, which might explain the convergent validity of level 3 of the Dutch version of the PGNG task. Hence, to overcome these potentially confounding factors, the Dutch version of the PGNG task should be investigated in a larger and more heterogeneous population in terms of age and educational level.","PeriodicalId":50671,"journal":{"name":"Cognitive and Behavioral Neurology","volume":" ","pages":"62-72"},"PeriodicalIF":1.4,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138488973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Barriers to the use of Methylphenidate in Pediatric Neuro-oncology Services. 儿童神经肿瘤服务中使用哌甲酯的障碍。

IF 1.4 4区医学

Cognitive and Behavioral Neurology Pub Date : 2024-06-01 DOI: 10.1097/WNN.0000000000000357

Alexander J Hagan, Simon Bailey, Sarah J Verity

{"title":"Barriers to the use of Methylphenidate in Pediatric Neuro-oncology Services.","authors":"Alexander J Hagan, Simon Bailey, Sarah J Verity","doi":"10.1097/WNN.0000000000000357","DOIUrl":"10.1097/WNN.0000000000000357","url":null,"abstract":"Background: Survivors of childhood CNS tumors are at a significant risk of chronic and multifaceted neurocognitive late effects. Recent findings indicate the potential utility of methylphenidate in addressing neurocognitive and academic plateauing and improving quality-of-life outcomes in this clinical population. However, the prescription of methylphenidate in neuro-oncology services remains inconsistent.Objective: To explore the neurocognitive assessment and rehabilitative interventions (including the use of methylphenidate) offered to survivors of childhood CNS tumors within mainland UK.Method: We used a semi-structured questionnaire to gather qualitative data from clinical psychologists and neuropsychologists within National Health Service pediatric neuro-oncology principal treatment centers (PTCs) during May 2018. Thematic analytical methods were used to explore themes within the collected data.Results: Eleven (58%) of the 19 PTCs returned the completed questionnaire. Respondents reported inadequate resource of psychology in many pediatric neuro-oncology PTCs, which limited the provision of methylphenidate to a restricted proportion of the patient group (i.e., those with the most profound neurocognitive difficulties). Respondents reported an interest in exploring the utility of methylphenidate in their patient group yet described a lack of appropriate evidence of its efficacy. In addition, respondents highlighted the need for the provision of accessible research summaries and treatment protocols addressing the use of methylphenidate.Conclusion: We anticipate that national collaboration between clinicians and researchers working in the cancer survivorship field will support the advancement of interventions such as methylphenidate for the growing clinical population of survivors of childhood CNS tumors.","PeriodicalId":50671,"journal":{"name":"Cognitive and Behavioral Neurology","volume":" ","pages":"57-61"},"PeriodicalIF":1.4,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41172289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Consciousness: How Our Brains Turn Matter Into Meaning. 意识：我们的大脑如何将物质转化为意义。

IF 1.3 4区医学

Cognitive and Behavioral Neurology Pub Date : 2024-06-01 DOI: 10.1097/WNN.0000000000000367

Howard S Kirshner

引用次数: 0

The Covenant of Water. 《水的盟约》。

IF 1.4 4区医学

Cognitive and Behavioral Neurology Pub Date : 2024-03-01 DOI: 10.1097/WNN.0000000000000360

Howard S Kirshner

引用次数: 0

Progress in Primary Progressive Aphasia: A Review. 原发性进行性失语症的研究进展：综述。

IF 1.4 4区医学

Cognitive and Behavioral Neurology Pub Date : 2024-03-01 DOI: 10.1097/WNN.0000000000000365

Andrew Kertesz, Elizabeth Finger, David G Munoz

引用次数: 0

Poststroke Executive Function in Relation to White Matter Damage on Clinically Acquired CT Brain Imaging. 脑卒中后执行功能与临床CT脑成像白质损伤的关系。

IF 1.4 4区医学

Cognitive and Behavioral Neurology Pub Date : 2024-03-01 DOI: 10.1097/WNN.0000000000000355

Georgina Hobden, Margaret Jane Moore, Grant Mair, Sarah T Pendlebury, Nele Demeyere

{"title":"Poststroke Executive Function in Relation to White Matter Damage on Clinically Acquired CT Brain Imaging.","authors":"Georgina Hobden, Margaret Jane Moore, Grant Mair, Sarah T Pendlebury, Nele Demeyere","doi":"10.1097/WNN.0000000000000355","DOIUrl":"10.1097/WNN.0000000000000355","url":null,"abstract":"Background: Executive function (EF) impairments are prevalent post stroke and are associated with white matter (WM) damage on MRI. However, less is known about the relationship between poststroke EF and WM damage on CT imaging.Objective: To investigate the relationship between poststroke EF and WM damage associated with stroke lesions and WM hypointensities (WMHs) on clinically acquired CT imaging.Method: This study analyzed data from the Oxford Cognitive Screening Program, which recruited individuals aged ≥18 years with a confirmed stroke from an acute stroke unit. The individuals completed a follow-up assessment 6 months post stroke. We included individuals with a CT scan showing a visible stroke who completed follow-up EF assessment using the Oxford Cognitive Screen-Plus rule-finding task. We manually delineated stroke lesions and quantified then dichotomized WM damage caused by the stroke using the HCP-842 atlas. We visually rated then dichotomized WMHs using the Age-Related White Matter Changes Scale.Results: Among 87 stroke survivors (M age = 73.60 ± 11.75; 41 female; 61 ischemic stroke), multivariable linear regression showed that stroke damage to the medial lemniscus ( B = -8.86, P < 0.001) and the presence of WMHs ( B = -5.42, P = 0.005) were associated with poorer EF 6 months post stroke after adjusting for covariates including age and education.Conclusion: Poorer EF was associated with WM damage caused by stroke lesions and WMHs on CT. These results confirm the importance of WM integrity for EF post stroke and demonstrate the prognostic utility of CT-derived imaging markers for poststroke cognitive outcomes.","PeriodicalId":50671,"journal":{"name":"Cognitive and Behavioral Neurology","volume":" ","pages":"23-31"},"PeriodicalIF":1.4,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41156247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Barriers to Alzheimer Disease Clinical Trial Participation in a Minority Population. 少数群体参与阿尔茨海默病临床试验的障碍。

IF 1.4 4区医学

Cognitive and Behavioral Neurology Pub Date : 2024-03-01 DOI: 10.1097/WNN.0000000000000359

Anson Y Lee, Julia R Jahansooz, Darrell Guittu, Rexton Suzuki, Lauren Pak, Kyle M Ishikawa, Connor Goo, John J Chen, Enrique Carrazana, Jason Viereck, Kore K Liow

{"title":"Barriers to Alzheimer Disease Clinical Trial Participation in a Minority Population.","authors":"Anson Y Lee, Julia R Jahansooz, Darrell Guittu, Rexton Suzuki, Lauren Pak, Kyle M Ishikawa, Connor Goo, John J Chen, Enrique Carrazana, Jason Viereck, Kore K Liow","doi":"10.1097/WNN.0000000000000359","DOIUrl":"10.1097/WNN.0000000000000359","url":null,"abstract":"Background: Alzheimer disease (AD), the most common neurodegenerative disorder in the United States, disproportionately burdens minority populations.Objective: To explore barriers to AD clinical trial participation by Asian and Native Hawaiian patients diagnosed with AD or mild cognitive impairment.Method: We surveyed 187 patients with a Mini-Mental State Examination score ≥14 between January 2022 and June 2022. The score cutoff for clinical trial eligibility was set by the institution. Individuals also completed a 15-question telephone survey that assessed demographics, barriers to clinical trial participation, and clinical trial improvement methods.Results: Forty-nine patients responded, with a response rate of 26%. Asian and Native Hawaiian patients were less likely than White patients to participate in AD trials. The main barrier to participation was a lack of information about AD trials. Providing additional information regarding AD trials to patients and family members were listed as the top two reasons patients would consider participating in a clinical trial.Conclusion: Insufficient information about AD clinical trials is the primary barrier to participation among Asian and Native Hawaiian patients, followed by difficulty coordinating transportation and, in the case of Asians, the time required for clinical trials. Increased outreach, education, and assistance with logistics in these populations should be pursued to improve rates of participation in clinical trials.","PeriodicalId":50671,"journal":{"name":"Cognitive and Behavioral Neurology","volume":" ","pages":"40-47"},"PeriodicalIF":1.4,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10948321/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50163517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cognitive Intra-individual Variability in the Laboratory Is Associated With Greater Executive Dysfunction in the Daily Lives of Older Adults With HIV. 实验室中的认知个体内变异性与艾滋病毒感染老年人日常生活中更大的执行功能障碍有关。

IF 1.4 4区医学

Cognitive and Behavioral Neurology Pub Date : 2024-03-01 DOI: 10.1097/WNN.0000000000000358

Natalie C Ridgely, Steven Paul Woods, Troy A Webber, Andrea I Mustafa, Darrian Evans

{"title":"Cognitive Intra-individual Variability in the Laboratory Is Associated With Greater Executive Dysfunction in the Daily Lives of Older Adults With HIV.","authors":"Natalie C Ridgely, Steven Paul Woods, Troy A Webber, Andrea I Mustafa, Darrian Evans","doi":"10.1097/WNN.0000000000000358","DOIUrl":"10.1097/WNN.0000000000000358","url":null,"abstract":"Background: Executive dysfunction, which is common among persons with HIV (PWH), can have an adverse impact on health behaviors and quality of life. Intra-individual variability (IIV) is a measure of within-person variability across cognitive tests that is higher in PWH and is thought to reflect cognitive dyscontrol.Objective: To assess whether cognitive IIV in the laboratory is associated with self-reported executive dysfunction in daily life among older PWH.Method: Participants included 71 PWH aged ≥50 years who completed six subtests from the Cogstate battery and two subscales from the Frontal Systems Behavior Scale (FrSBe; self-report version). Cognitive IIV was calculated from the Cogstate as the coefficient of variation derived from age-adjusted normative T scores.Results: Cognitive IIV as measured by the Cogstate showed a significant, positive, medium-sized association with current FrSBe ratings of executive dysfunction but not disinhibition.Conclusion: Higher cognitive IIV in the laboratory as measured by the Cogstate may be related to the expression of HIV-associated symptoms of executive dysfunction in daily life for older PWH.","PeriodicalId":50671,"journal":{"name":"Cognitive and Behavioral Neurology","volume":" ","pages":"32-39"},"PeriodicalIF":1.4,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10948322/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49693571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0