Current Opinion in Ophthalmology最新文献_第5页

IF 3 2区医学

Current Opinion in Ophthalmology Pub Date : 2025-03-01 Epub Date: 2025-01-09 DOI: 10.1097/ICU.0000000000001110

Anthony P Mai, Tanner J Ferguson, Nathan Radcliffe

{"title":"New treatments for glaucoma.","authors":"Anthony P Mai, Tanner J Ferguson, Nathan Radcliffe","doi":"10.1097/ICU.0000000000001110","DOIUrl":"10.1097/ICU.0000000000001110","url":null,"abstract":"Purpose of review: This review highlights new Federal Drug Administration (FDA) approved glaucoma treatments to familiarize providers with immediately available options.Recent findings: New FDA-approved treatments include the bimatoprost implant, travoprost implant, direct selective laser trabeculoplasty (DSLT), and ocular pressure adjusting pump. The bimatoprost implant is approved for a single administration with effects lasting for about 1 year, as opposed to the nearly 3-year effect for the travoprost implant. Meanwhile, the DSLT lowers intraocular pressure (IOP) by applying a laser through the limbus within 2 s. Lastly, the ocular pressure adjusting pump is a noninvasive, nonpharmaceutical device that lowers IOP with negative pressure within a pair of goggles. Not only do these modalities lower IOP, but they also improve the patient experience by reducing drop burden, decreasing laser duration, or lowering side effects. Although the list of therapies still in development is extensive, another two promising devices under review include a supraciliary stent and an adjustable aqueous tube shunt.Summary: Glaucoma treatment has considerably evolved over the last decade with the introduction of novel topical medications, minimally invasive glaucoma surgeries, sustained-release drug delivery systems, and wearable devices. This expansion in glaucoma has enabled more patient-centric decision-making regarding treatment.","PeriodicalId":50604,"journal":{"name":"Current Opinion in Ophthalmology","volume":" ","pages":"135-139"},"PeriodicalIF":3.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142958354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Overlap syndrome: a case series and literature review of concurrent pigment dispersion and pseudoexfoliation syndromes. 重叠综合征：并发色素分散和假性剥脱综合征的病例系列和文献综述。

IF 3 2区医学

Current Opinion in Ophthalmology Pub Date : 2025-03-01 Epub Date: 2024-11-07 DOI: 10.1097/ICU.0000000000001107

Pooja Shah, Srinath Soundararajan, David Fleischman

{"title":"Overlap syndrome: a case series and literature review of concurrent pigment dispersion and pseudoexfoliation syndromes.","authors":"Pooja Shah, Srinath Soundararajan, David Fleischman","doi":"10.1097/ICU.0000000000001107","DOIUrl":"10.1097/ICU.0000000000001107","url":null,"abstract":"Purpose of review: The purpose of this review is to present two cases of overlap syndrome, or concurrent pigment dispersion syndrome and pseudoexfoliation syndrome. The summary of existing literature highlights the importance of accurate diagnosis and potential treatment options of overlap syndrome.Recent findings: The cases describe two patients with overlap syndrome and resulting progressive glaucoma. The condition tends to present after age 50 years old, with presence of both pseudoexfoliative material and pigment dispersion signs. The pigment dispersion syndrome may be quiescent at the time of pseudoexfoliation onset and may have gone undiagnosed. This form of glaucoma poses challenges in controlling intraocular pressure and may progress rapidly, often requiring surgical intervention.Summary: This paper reviews the common examination findings of pigment dispersion syndrome and pseudoexfoliation, which may aid clinicians in the diagnosis of the rare condition, overlap syndrome. The connection between the two conditions remains unclear, though studies of possible genetic associations are underway. The two-hit theory, or initial damage to the trabecular meshwork increasing susceptibility to future damage, is plausible given the severe nature of the condition. Though definitive conclusions regarding treatment strategies and outcomes of overlap syndrome are lacking, increased awareness, diagnosis, and study of the condition may help guide the management of overlap syndrome.","PeriodicalId":50604,"journal":{"name":"Current Opinion in Ophthalmology","volume":" ","pages":"122-129"},"PeriodicalIF":3.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142607464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Reporting outcomes of minimally invasive glaucoma surgery. 报告微创青光眼手术的结果。

IF 3 2区医学

Current Opinion in Ophthalmology Pub Date : 2025-03-01 Epub Date: 2024-10-28 DOI: 10.1097/ICU.0000000000001100

Naomi E Gutkind, Steven J Gedde

{"title":"Reporting outcomes of minimally invasive glaucoma surgery.","authors":"Naomi E Gutkind, Steven J Gedde","doi":"10.1097/ICU.0000000000001100","DOIUrl":"10.1097/ICU.0000000000001100","url":null,"abstract":"Purpose of review: This review presents guidelines for designing studies and reporting efficacy and safety outcomes in minimally invasive glaucoma surgery (MIGS) research.Recent findings: Adherence to reporting guidelines in MIGS studies is crucial for providers and patients to appraise surgical options. Recent guidelines have outlined appropriate methodology, efficacy outcomes, and safety reporting, so that study results are presented in an interpretable and uniform manner.Summary: MIGS are changing the glaucoma treatment paradigm by offering safer, less invasive alternatives to traditional filtering surgery. However, inconsistent reporting of outcomes in MIGS trials hampers comparison and clinical decision-making. Recent guidelines have aimed to highlight appropriate methodology and encourage standardization in reporting outcomes to improve the quality of MIGS literature. Key considerations include defining baseline intraocular pressure, reporting standardized demographic data, using consistent endpoints, presenting standardized figures, evaluating medication use, and documenting adverse events. By adhering to these guidelines, MIGS trials can offer clearer insights into surgical outcomes, aiding both surgeons and patients in treatment decisions.","PeriodicalId":50604,"journal":{"name":"Current Opinion in Ophthalmology","volume":" ","pages":"140-145"},"PeriodicalIF":3.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142523531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diagnosing glaucoma progression with optical coherence tomography. 利用光学相干断层扫描诊断青光眼进展。

IF 3 2区医学

Current Opinion in Ophthalmology Pub Date : 2025-03-01 Epub Date: 2024-11-07 DOI: 10.1097/ICU.0000000000001106

Laura D Palmer, Atalie C Thompson, Sanjay Asrani

{"title":"Diagnosing glaucoma progression with optical coherence tomography.","authors":"Laura D Palmer, Atalie C Thompson, Sanjay Asrani","doi":"10.1097/ICU.0000000000001106","DOIUrl":"10.1097/ICU.0000000000001106","url":null,"abstract":"Purpose of review: Optical coherence tomography (OCT) is a widely used tool to diagnose and monitor glaucoma by objectively measuring the ganglion cell layer and the retinal nerve fiber layer (RNFL) thickness. The presence of RNFL thinning raises suspicion for glaucoma progression. Therefore, this review aims to discuss current approaches to using OCT for detecting glaucomatous change, limitations, and recent advancements.Recent findings: Previously established approaches to determining glaucomatous progression on OCT include quantitative and qualitative methods. The most common quantitative methods include event-based and trend-based analysis. Decreasing RNFL thickness or loss of the ganglion cell layer are indicative of glaucomatous changes. However, interpretation of OCT scans is strongly impacted by artifacts, which can be because of epiretinal membrane or posterior vitreous detachment. Race and aging also may impact interpretation of RNFL progression. More recent research focuses on loss of the RNFL because of the effects of systemic conditions. Given the limitations in the current approaches, recent advancements indicate a promising role for artificial intelligence in determining true glaucomatous progression.Summary: This review highlights current approaches to identifying glaucoma progression on OCT, limitations to these approaches, and the potential role for artificial intelligence.","PeriodicalId":50604,"journal":{"name":"Current Opinion in Ophthalmology","volume":" ","pages":"130-134"},"PeriodicalIF":3.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142607463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Is minimally invasive glaucoma surgery killing trabeculectomies? 微创青光眼手术会杀死小梁切除术吗？

IF 3 2区医学

Current Opinion in Ophthalmology Pub Date : 2025-03-01 Epub Date: 2024-11-13 DOI: 10.1097/ICU.0000000000001108

Seng Chee Loon, Bryan Chin Hou Ang, Andrew White

引用次数: 0

Minimally invasive glaucoma surgery in angle closure. 微创青光眼闭角手术。

IF 3 2区医学

Current Opinion in Ophthalmology Pub Date : 2025-03-01 Epub Date: 2024-12-18 DOI: 10.1097/ICU.0000000000001117

Nicole Shu-Wen Chan, Chelvin C A Sng

引用次数: 0

Clinical pearls from glaucoma clinical trials: a case-based approach. 青光眼临床试验的临床珍珠：基于病例的方法。

IF 3 2区医学

Current Opinion in Ophthalmology Pub Date : 2025-03-01 Epub Date: 2024-11-20 DOI: 10.1097/ICU.0000000000001113

Laura E Barna, In Young Chung, Lucy Q Shen

引用次数: 0

Foundation models in ophthalmology: opportunities and challenges. 眼科基础模式：机遇与挑战。

IF 3 2区医学

Current Opinion in Ophthalmology Pub Date : 2025-01-01 Epub Date: 2024-11-04 DOI: 10.1097/ICU.0000000000001091

Mertcan Sevgi, Eden Ruffell, Fares Antaki, Mark A Chia, Pearse A Keane

{"title":"Foundation models in ophthalmology: opportunities and challenges.","authors":"Mertcan Sevgi, Eden Ruffell, Fares Antaki, Mark A Chia, Pearse A Keane","doi":"10.1097/ICU.0000000000001091","DOIUrl":"10.1097/ICU.0000000000001091","url":null,"abstract":"Purpose of review: Last year marked the development of the first foundation model in ophthalmology, RETFound, setting the stage for generalizable medical artificial intelligence (GMAI) that can adapt to novel tasks. Additionally, rapid advancements in large language model (LLM) technology, including models such as GPT-4 and Gemini, have been tailored for medical specialization and evaluated on clinical scenarios with promising results. This review explores the opportunities and challenges for further advancements in these technologies.Recent findings: RETFound outperforms traditional deep learning models in specific tasks, even when only fine-tuned on small datasets. Additionally, LMMs like Med-Gemini and Medprompt GPT-4 perform better than out-of-the-box models for ophthalmology tasks. However, there is still a significant deficiency in ophthalmology-specific multimodal models. This gap is primarily due to the substantial computational resources required to train these models and the limitations of high-quality ophthalmology datasets.Summary: Overall, foundation models in ophthalmology present promising opportunities but face challenges, particularly the need for high-quality, standardized datasets for training and specialization. Although development has primarily focused on large language and vision models, the greatest opportunities lie in advancing large multimodal models, which can more closely mimic the capabilities of clinicians.","PeriodicalId":50604,"journal":{"name":"Current Opinion in Ophthalmology","volume":" ","pages":"90-98"},"PeriodicalIF":3.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11620320/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142331709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A comprehensive update on over the counter artificial tears. 全面更新非处方人工泪液。

IF 3 2区医学

Current Opinion in Ophthalmology Pub Date : 2025-01-01 Epub Date: 2024-11-08 DOI: 10.1097/ICU.0000000000001109

Lilla Simon, Brian A Murillo, Alfonso L Sabater

引用次数: 0

Global prevalence of cataract surgery. 白内障手术的全球患病率。

IF 3 2区医学

Current Opinion in Ophthalmology Pub Date : 2025-01-01 Epub Date: 2024-09-25 DOI: 10.1097/ICU.0000000000001092

Hassan Hashemi, Faezeh Fayaz, Alireza Hashemi, Mehdi Khabazkhoob

{"title":"Global prevalence of cataract surgery.","authors":"Hassan Hashemi, Faezeh Fayaz, Alireza Hashemi, Mehdi Khabazkhoob","doi":"10.1097/ICU.0000000000001092","DOIUrl":"https://doi.org/10.1097/ICU.0000000000001092","url":null,"abstract":"Purpose of review: The objective of this review article is to ascertain the global distribution of cataract surgery and evaluate the extent of its coverage in recent years.Recent findings: The cataract surgical rate (CSR) has been reported from 36 to 12 800 (per million population) across different countries. The average cataract surgical coverage (CSC) in the majority of countries was around 50% or lower. Additionally, in many countries, the efficient CSC (eCSC) deviates from the CSC, emphasizing the importance of attention to the quality of surgical procedures. Socioeconomic status and access to health services are key determinants in the distribution of cataract surgery. This procedure is more prevalent among older individuals, with a higher incidence among men and private insurances tend to cover a larger portion of cataract surgeries. The pandemic of COVID-19 has had a detrimental effect on cataract surgery rates in numerous countries.Summary: The rate of cataract surgery and its extent of coverage in certain countries is inadequate. The primary factor influencing the quantity and coverage of cataract surgeries is the economic status of the countries. Additionally, government support through insurance and the provision of appropriate healthcare services can contribute to an increase in cataract surgeries.","PeriodicalId":50604,"journal":{"name":"Current Opinion in Ophthalmology","volume":"36 1","pages":"10-17"},"PeriodicalIF":3.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142786378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0