青光眼的新疗法。

IF 3 2区 医学 Q1 OPHTHALMOLOGY
Anthony P Mai, Tanner J Ferguson, Nathan Radcliffe
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引用次数: 0

摘要

综述目的:本综述强调了美国联邦药物管理局(FDA)批准的新的青光眼治疗方法,以使提供者熟悉立即可用的选择。最新发现:fda批准的新疗法包括比马前列素植入物、曲伏前列素植入物、直接选择性激光小梁成形术(DSLT)和眼压调节泵。比马前列素植入物被批准为单次给药,效果持续约1年,而曲伏前列素植入物的效果持续近3年。同时,DSLT通过在2秒内通过角膜缘照射激光来降低眼压。最后,眼压调节泵是一种无创、非药物装置,可在一副护目镜内以负压降低眼压。这些方法不仅可以降低IOP,而且还可以通过减少眼压、缩短激光持续时间或降低副作用来改善患者的体验。尽管仍在开发的治疗方法有很多,但另外两种有前景的设备正在审查中,包括辅助支架和可调节的水管分流器。摘要:青光眼的治疗在过去十年中有了很大的发展,引入了新的局部药物,微创青光眼手术,缓释药物输送系统和可穿戴设备。青光眼的扩大使得治疗决策更加以患者为中心。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
New treatments for glaucoma.

Purpose of review: This review highlights new Federal Drug Administration (FDA) approved glaucoma treatments to familiarize providers with immediately available options.

Recent findings: New FDA-approved treatments include the bimatoprost implant, travoprost implant, direct selective laser trabeculoplasty (DSLT), and ocular pressure adjusting pump. The bimatoprost implant is approved for a single administration with effects lasting for about 1 year, as opposed to the nearly 3-year effect for the travoprost implant. Meanwhile, the DSLT lowers intraocular pressure (IOP) by applying a laser through the limbus within 2 s. Lastly, the ocular pressure adjusting pump is a noninvasive, nonpharmaceutical device that lowers IOP with negative pressure within a pair of goggles. Not only do these modalities lower IOP, but they also improve the patient experience by reducing drop burden, decreasing laser duration, or lowering side effects. Although the list of therapies still in development is extensive, another two promising devices under review include a supraciliary stent and an adjustable aqueous tube shunt.

Summary: Glaucoma treatment has considerably evolved over the last decade with the introduction of novel topical medications, minimally invasive glaucoma surgeries, sustained-release drug delivery systems, and wearable devices. This expansion in glaucoma has enabled more patient-centric decision-making regarding treatment.

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来源期刊
CiteScore
6.80
自引率
5.40%
发文量
120
审稿时长
6-12 weeks
期刊介绍: Current Opinion in Ophthalmology is an indispensable resource featuring key up-to-date and important advances in the field from around the world. With renowned guest editors for each section, every bimonthly issue of Current Opinion in Ophthalmology delivers a fresh insight into topics such as glaucoma, refractive surgery and corneal and external disorders. With ten sections in total, the journal provides a convenient and thorough review of the field and will be of interest to researchers, clinicians and other healthcare professionals alike.
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