Current Opinion in Ophthalmology最新文献

Editorial introduction.

IF 3 2区医学

Current Opinion in Ophthalmology Pub Date : 2025-03-01 Epub Date: 2025-02-02 DOI: 10.1097/ICU.0000000000001114

引用次数: 0

Implications of myopia in diagnosis and screening of open angle glaucoma. 近视在开角型青光眼诊断和筛查中的意义。

IF 3 2区医学

Current Opinion in Ophthalmology Pub Date : 2025-03-01 Epub Date: 2024-12-23 DOI: 10.1097/ICU.0000000000001116

Aiko Iwase, Makoto Araie

{"title":"Implications of myopia in diagnosis and screening of open angle glaucoma.","authors":"Aiko Iwase, Makoto Araie","doi":"10.1097/ICU.0000000000001116","DOIUrl":"10.1097/ICU.0000000000001116","url":null,"abstract":"Purpose of review: Rapid increase in the prevalence of myopia has been documented worldwide. Myopia, especially high myopia, is not only an important risk factor for having open angle glaucoma (OAG), but also has a strong linking with the progression of OAG. Since myopic axial length (AXL) elongation is associated with nonglaucomatous optic nerve head (ONH) and visual field abnormalities, myopia poses a challenge in differential diagnosis of OAG. This review provides an overview of literature studying relationships between myopic AXL-elongation and diagnosis and prognosis of OAG, and functional and structural changes in the eye.Recent findings: Studies using optical coherence tomography (OCT), OCT-angiography, those using standard automated perimetry (SAP), other perimetric or electrophysiological methods showed dose-dependent effects of myopic AXL elongation on the structural changes in the ONH and parapapillary tissues, and functional abnormalities of an eye. Large cohort studies showed approximately one quarter of eyes with nonpathologic high myopia were complicated with various patterns of visual field defects including glaucoma-like ones.Summary: Findings of cross-sectional and longitudinal studies obtained using various fundus imaging devices must be integrated to perimetric results to improve differential diagnosis of OAG in myopic eyes, in which artificial intelligence technology may be useful.","PeriodicalId":50604,"journal":{"name":"Current Opinion in Ophthalmology","volume":" ","pages":"107-114"},"PeriodicalIF":3.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142869787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Lifestyle modifications and environmental risk factors for glaucoma. 青光眼的生活方式改变和环境风险因素。

IF 3 2区医学

Current Opinion in Ophthalmology Pub Date : 2025-03-01 Epub Date: 2024-10-23 DOI: 10.1097/ICU.0000000000001098

Abdelrahman M Elhusseiny, Ahmad A Aref

{"title":"Lifestyle modifications and environmental risk factors for glaucoma.","authors":"Abdelrahman M Elhusseiny, Ahmad A Aref","doi":"10.1097/ICU.0000000000001098","DOIUrl":"10.1097/ICU.0000000000001098","url":null,"abstract":"Purpose of review: To summarize recent evidence about the association between different lifestyle modifications and environmental risk factors and glaucoma.Recent findings: Incorporating moderate exercise into the routine of glaucoma patients may help slow the progression of the condition. However, caution should be taken when using swim goggles, and it may be advisable to avoid certain yoga positions and heavy weight-lifting exercises, as they have been linked to intraocular pressure (IOP) spikes and potential risks for glaucoma patients. Various relaxation techniques may lower IOP. The evidence remains inconclusive about the association between vitamins intake and glaucoma. Dietary nitric oxide has been associated with a lower risk of glaucoma. Higher smoking intensity has been linked to faster visual field decline and retinal nerve fiber layer thinning. Additionally, there is currently insufficient evidence to support the use of marijuana in managing glaucoma, with side effects outweighing the proposed benefits. A significant association has been found between air pollutants and ganglion cell layer thinning, as well as a greater burden of glaucoma.Summary: Lifestyle and environmental factors are increasingly recognized as significant contributors to glaucoma development and progression. These modifications should be integrated into a comprehensive treatment approach alongside medications or surgical interventions.","PeriodicalId":50604,"journal":{"name":"Current Opinion in Ophthalmology","volume":" ","pages":"115-121"},"PeriodicalIF":3.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142512327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Overlap syndrome: a case series and literature review of concurrent pigment dispersion and pseudoexfoliation syndromes. 重叠综合征：并发色素分散和假性剥脱综合征的病例系列和文献综述。

IF 3 2区医学

Current Opinion in Ophthalmology Pub Date : 2025-03-01 Epub Date: 2024-11-07 DOI: 10.1097/ICU.0000000000001107

Pooja Shah, Srinath Soundararajan, David Fleischman

{"title":"Overlap syndrome: a case series and literature review of concurrent pigment dispersion and pseudoexfoliation syndromes.","authors":"Pooja Shah, Srinath Soundararajan, David Fleischman","doi":"10.1097/ICU.0000000000001107","DOIUrl":"10.1097/ICU.0000000000001107","url":null,"abstract":"Purpose of review: The purpose of this review is to present two cases of overlap syndrome, or concurrent pigment dispersion syndrome and pseudoexfoliation syndrome. The summary of existing literature highlights the importance of accurate diagnosis and potential treatment options of overlap syndrome.Recent findings: The cases describe two patients with overlap syndrome and resulting progressive glaucoma. The condition tends to present after age 50 years old, with presence of both pseudoexfoliative material and pigment dispersion signs. The pigment dispersion syndrome may be quiescent at the time of pseudoexfoliation onset and may have gone undiagnosed. This form of glaucoma poses challenges in controlling intraocular pressure and may progress rapidly, often requiring surgical intervention.Summary: This paper reviews the common examination findings of pigment dispersion syndrome and pseudoexfoliation, which may aid clinicians in the diagnosis of the rare condition, overlap syndrome. The connection between the two conditions remains unclear, though studies of possible genetic associations are underway. The two-hit theory, or initial damage to the trabecular meshwork increasing susceptibility to future damage, is plausible given the severe nature of the condition. Though definitive conclusions regarding treatment strategies and outcomes of overlap syndrome are lacking, increased awareness, diagnosis, and study of the condition may help guide the management of overlap syndrome.","PeriodicalId":50604,"journal":{"name":"Current Opinion in Ophthalmology","volume":" ","pages":"122-129"},"PeriodicalIF":3.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142607464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

New treatments for glaucoma. 青光眼的新疗法。

IF 3 2区医学

Current Opinion in Ophthalmology Pub Date : 2025-03-01 Epub Date: 2025-01-09 DOI: 10.1097/ICU.0000000000001110

Anthony P Mai, Tanner J Ferguson, Nathan Radcliffe

{"title":"New treatments for glaucoma.","authors":"Anthony P Mai, Tanner J Ferguson, Nathan Radcliffe","doi":"10.1097/ICU.0000000000001110","DOIUrl":"10.1097/ICU.0000000000001110","url":null,"abstract":"Purpose of review: This review highlights new Federal Drug Administration (FDA) approved glaucoma treatments to familiarize providers with immediately available options.Recent findings: New FDA-approved treatments include the bimatoprost implant, travoprost implant, direct selective laser trabeculoplasty (DSLT), and ocular pressure adjusting pump. The bimatoprost implant is approved for a single administration with effects lasting for about 1 year, as opposed to the nearly 3-year effect for the travoprost implant. Meanwhile, the DSLT lowers intraocular pressure (IOP) by applying a laser through the limbus within 2 s. Lastly, the ocular pressure adjusting pump is a noninvasive, nonpharmaceutical device that lowers IOP with negative pressure within a pair of goggles. Not only do these modalities lower IOP, but they also improve the patient experience by reducing drop burden, decreasing laser duration, or lowering side effects. Although the list of therapies still in development is extensive, another two promising devices under review include a supraciliary stent and an adjustable aqueous tube shunt.Summary: Glaucoma treatment has considerably evolved over the last decade with the introduction of novel topical medications, minimally invasive glaucoma surgeries, sustained-release drug delivery systems, and wearable devices. This expansion in glaucoma has enabled more patient-centric decision-making regarding treatment.","PeriodicalId":50604,"journal":{"name":"Current Opinion in Ophthalmology","volume":" ","pages":"135-139"},"PeriodicalIF":3.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142958354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Reporting outcomes of minimally invasive glaucoma surgery. 报告微创青光眼手术的结果。

IF 3 2区医学

Current Opinion in Ophthalmology Pub Date : 2025-03-01 Epub Date: 2024-10-28 DOI: 10.1097/ICU.0000000000001100

Naomi E Gutkind, Steven J Gedde

{"title":"Reporting outcomes of minimally invasive glaucoma surgery.","authors":"Naomi E Gutkind, Steven J Gedde","doi":"10.1097/ICU.0000000000001100","DOIUrl":"10.1097/ICU.0000000000001100","url":null,"abstract":"Purpose of review: This review presents guidelines for designing studies and reporting efficacy and safety outcomes in minimally invasive glaucoma surgery (MIGS) research.Recent findings: Adherence to reporting guidelines in MIGS studies is crucial for providers and patients to appraise surgical options. Recent guidelines have outlined appropriate methodology, efficacy outcomes, and safety reporting, so that study results are presented in an interpretable and uniform manner.Summary: MIGS are changing the glaucoma treatment paradigm by offering safer, less invasive alternatives to traditional filtering surgery. However, inconsistent reporting of outcomes in MIGS trials hampers comparison and clinical decision-making. Recent guidelines have aimed to highlight appropriate methodology and encourage standardization in reporting outcomes to improve the quality of MIGS literature. Key considerations include defining baseline intraocular pressure, reporting standardized demographic data, using consistent endpoints, presenting standardized figures, evaluating medication use, and documenting adverse events. By adhering to these guidelines, MIGS trials can offer clearer insights into surgical outcomes, aiding both surgeons and patients in treatment decisions.","PeriodicalId":50604,"journal":{"name":"Current Opinion in Ophthalmology","volume":" ","pages":"140-145"},"PeriodicalIF":3.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142523531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diagnosing glaucoma progression with optical coherence tomography. 利用光学相干断层扫描诊断青光眼进展。

IF 3 2区医学

Current Opinion in Ophthalmology Pub Date : 2025-03-01 Epub Date: 2024-11-07 DOI: 10.1097/ICU.0000000000001106

Laura D Palmer, Atalie C Thompson, Sanjay Asrani

{"title":"Diagnosing glaucoma progression with optical coherence tomography.","authors":"Laura D Palmer, Atalie C Thompson, Sanjay Asrani","doi":"10.1097/ICU.0000000000001106","DOIUrl":"10.1097/ICU.0000000000001106","url":null,"abstract":"Purpose of review: Optical coherence tomography (OCT) is a widely used tool to diagnose and monitor glaucoma by objectively measuring the ganglion cell layer and the retinal nerve fiber layer (RNFL) thickness. The presence of RNFL thinning raises suspicion for glaucoma progression. Therefore, this review aims to discuss current approaches to using OCT for detecting glaucomatous change, limitations, and recent advancements.Recent findings: Previously established approaches to determining glaucomatous progression on OCT include quantitative and qualitative methods. The most common quantitative methods include event-based and trend-based analysis. Decreasing RNFL thickness or loss of the ganglion cell layer are indicative of glaucomatous changes. However, interpretation of OCT scans is strongly impacted by artifacts, which can be because of epiretinal membrane or posterior vitreous detachment. Race and aging also may impact interpretation of RNFL progression. More recent research focuses on loss of the RNFL because of the effects of systemic conditions. Given the limitations in the current approaches, recent advancements indicate a promising role for artificial intelligence in determining true glaucomatous progression.Summary: This review highlights current approaches to identifying glaucoma progression on OCT, limitations to these approaches, and the potential role for artificial intelligence.","PeriodicalId":50604,"journal":{"name":"Current Opinion in Ophthalmology","volume":" ","pages":"130-134"},"PeriodicalIF":3.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142607463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Is minimally invasive glaucoma surgery killing trabeculectomies? 微创青光眼手术会杀死小梁切除术吗？

IF 3 2区医学

Current Opinion in Ophthalmology Pub Date : 2025-03-01 Epub Date: 2024-11-13 DOI: 10.1097/ICU.0000000000001108

Seng Chee Loon, Bryan Chin Hou Ang, Andrew White

引用次数: 0

Minimally invasive glaucoma surgery in angle closure. 微创青光眼闭角手术。

IF 3 2区医学

Current Opinion in Ophthalmology Pub Date : 2025-03-01 Epub Date: 2024-12-18 DOI: 10.1097/ICU.0000000000001117

Nicole Shu-Wen Chan, Chelvin C A Sng

引用次数: 0

Clinical pearls from glaucoma clinical trials: a case-based approach. 青光眼临床试验的临床珍珠：基于病例的方法。