Current Opinion in Ophthalmology最新文献_第10页

Refractive cataract surgery. 屈光白内障手术。

IF 3.7 2区医学

Current Opinion in Ophthalmology Pub Date : 2024-01-01 Epub Date: 2023-11-14 DOI: 10.1097/ICU.0000000000001005

Rhea Narang, Ashvin Agarwal

引用次数: 0

Cataract surgery after corneal refractive surgery: preoperative considerations and management. 角膜屈光手术后白内障手术:术前注意事项及处理。

IF 3.7 2区医学

Current Opinion in Ophthalmology Pub Date : 2024-01-01 Epub Date: 2023-11-14 DOI: 10.1097/ICU.0000000000001006

Darren S J Ting, Damien Gatinel, Marcus Ang

{"title":"Cataract surgery after corneal refractive surgery: preoperative considerations and management.","authors":"Darren S J Ting, Damien Gatinel, Marcus Ang","doi":"10.1097/ICU.0000000000001006","DOIUrl":"10.1097/ICU.0000000000001006","url":null,"abstract":"Purpose of review: Corneal refractive surgery (CRS) is one of the most popular eye procedures, with more than 40 million cases performed globally. As CRS-treated patients age and develop cataract, the number of cases that require additional preoperative considerations and management will increase around the world. Thus, we provide an up-to-date, concise overview of the considerations and outcomes of cataract surgery in eyes with previous CRS, including surface ablation, laser in-situ keratomileusis (LASIK), and small-incision lenticule extraction (SMILE).Recent findings: Challenges associated with accurate biometry in eyes with CRS have been mitigated recently through total keratometry, ray tracing, intraoperative aberrometry, and machine learning assisted intraocular lens (IOL) power calculation formulas to improve prediction. Emerging studies have highlighted the superior performance of ray tracing and/or total keratometry-based formulas for IOL power calculation in eyes with previous SMILE. Dry eye remains a common side effect after cataract surgery, especially in eyes with CRS, though the risk appears to be lower after SMILE than LASIK (in the short-term). Recent presbyopia-correcting IOL designs such as extended depth of focus (EDOF) IOLs may be suitable in carefully selected eyes with previous CRS.Summary: Ophthalmologists will increasingly face challenges associated with the surgical management of cataract in patients with prior CRS. Careful preoperative assessment of the ocular surface, appropriate use of IOL power calculation formulas, and strategies for presbyopia correction are key to achieve good clinical and refractive outcomes and patient satisfaction. Recent advances in CRS techniques, such as SMILE, may pose new challenges for such eyes in the future.","PeriodicalId":50604,"journal":{"name":"Current Opinion in Ophthalmology","volume":" ","pages":"4-10"},"PeriodicalIF":3.7,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"92157248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Outcomes and predictive factors in multifocal and extended depth of focus intraocular lens implantation. 多焦点和扩大焦点深度人工晶状体植入的结果和预测因素。

IF 3.7 2区医学

Current Opinion in Ophthalmology Pub Date : 2024-01-01 Epub Date: 2023-11-01 DOI: 10.1097/ICU.0000000000001013

Matthew De la Paz, Linda M Tsai

{"title":"Outcomes and predictive factors in multifocal and extended depth of focus intraocular lens implantation.","authors":"Matthew De la Paz, Linda M Tsai","doi":"10.1097/ICU.0000000000001013","DOIUrl":"10.1097/ICU.0000000000001013","url":null,"abstract":"Purpose of review: Options for addressing presbyopia with intraocular lens (IOL) implantation have become more varied and sophisticated. We reviewed recent literature on multifocal and extended depth of focus (EDOF) IOLs in order to provide insight on their respective advantages, with emphasis on the visual outcomes of each design.Recent findings: Increased patient age, spectral domain optical coherence tomography (SD-OCT) abnormalities, abnormal optical axis measurements, and better preoperative visual acuity have been implicated as predictors of worse postoperative vision or visual quality in multifocal IOLs. Despite differences in objective outcomes, patient-reported outcomes such as satisfaction are consistently similar between multifocal and EDOF IOLs. EDOFs may have slightly lower rates of spectacle independence than trifocals, but there is more support for their use in the setting of with other ocular conditions.Summary: Multifocal and EDOF IOLs are both viable options for patients who wish to preserve near vision. Given their similar objective performance in many aspects, enabling patients to make informed decisions based on their expectations and visual requirements is critical to postoperative satisfaction. Evidence for advanced technology IOL implantation in pediatric patients remains inconclusive.","PeriodicalId":50604,"journal":{"name":"Current Opinion in Ophthalmology","volume":" ","pages":"28-33"},"PeriodicalIF":3.7,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71428710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Online intraocular lens calculation. 在线人工晶状体计算。

IF 3.7 2区医学

Current Opinion in Ophthalmology Pub Date : 2024-01-01 Epub Date: 2023-11-03 DOI: 10.1097/ICU.0000000000001014

Dante Buonsanti, Miguel Raimundo, Oliver Findl

引用次数: 0

Immediately sequential bilateral cataract surgery. 立即连续进行双侧白内障手术。

IF 3.7 2区医学

Current Opinion in Ophthalmology Pub Date : 2024-01-01 Epub Date: 2023-10-19 DOI: 10.1097/ICU.0000000000001003

Ali Nowrouzi, Jorge L Alió

{"title":"Immediately sequential bilateral cataract surgery.","authors":"Ali Nowrouzi, Jorge L Alió","doi":"10.1097/ICU.0000000000001003","DOIUrl":"10.1097/ICU.0000000000001003","url":null,"abstract":"Purpose of review: This review aims to clarify the advantages and disadvantages of immediately sequential bilateral cataract surgery (ISBCS) based on recent studies, illustrate the safety of this approach, the cost-effectiveness, and present the importance of inclusion protocols for the best results.Recent findings: In recent studies, the authors found no evidence of an increased risk of bilateral devastating complications such as endophthalmitis with ISBCS based on descriptive evidence compared to delayed sequential bilateral cataract surgery (DSBCS). Furthermore, recent studies on cost analyses showed that ISBCS resulted in fewer costs and significant cost savings to third-party payers, patients, and society compared to DSBCS.Summary: The ISBCS surgical approach decreases hospital visits, reduces costs, and provides rapid visual rehabilitation and neuro adaptation. The risk of bilateral simultaneous complications is now recognized to be very rare with intracameral antibiotics and compliance with correct protocols. With new generations of optical biometry and lens calculation formulas, refractive surprises are occasional for normal eyes. However, refractive surprise is controversial, especially in the implantation of presbyopia correction intra-ocular lenses, which must be evaluated carefully in the ISBCS approach.","PeriodicalId":50604,"journal":{"name":"Current Opinion in Ophthalmology","volume":"35 1","pages":"17-22"},"PeriodicalIF":3.7,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139933993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Oxidative stress and antioxidants in cataract development. 白内障发生过程中的氧化应激和抗氧化剂。

IF 3.7 2区医学

Current Opinion in Ophthalmology Pub Date : 2024-01-01 Epub Date: 2023-10-26 DOI: 10.1097/ICU.0000000000001009

Bryanna Lee, Natalie A Afshari, Peter X Shaw

{"title":"Oxidative stress and antioxidants in cataract development.","authors":"Bryanna Lee, Natalie A Afshari, Peter X Shaw","doi":"10.1097/ICU.0000000000001009","DOIUrl":"10.1097/ICU.0000000000001009","url":null,"abstract":"Purpose of review: Oxidative stress plays a central role in cataract pathogenesis, a leading cause of global blindness. This review delves into the role of oxidative stress in cataract development and key biomarkers - glutathione (GSH), superoxide dismutase (SOD), malondialdehyde (MDA), and 4-hydroxynonenal (4-HNE) - to clarify their functions and potential applications in predictive diagnostics and therapies.Recent findings: Antioxidants serve as pivotal markers in cataract pathogenesis. GSH affects the central lens due to factors such as enzyme depletion and altered connexin expression, impairing GSH diffusion. Age-related oxidative stress may hinder GSH transport via connexin channels or an internal microcirculation system. N-acetylcysteine, a GSH precursor, shows promise in mitigating lens opacity when applied topically. Additionally, SOD, particularly SOD1, correlates with increased cataract development and gel formulations have exhibited protective effects against posterior subscapular cataracts. Lastly, markers of lipid peroxidation, MDA and 4-HNE, have been shown to reflect disease severity. Studies suggest a potential link between 4-HNE and connexin channel modification, possibly contributing to reduced GSH levels.Summary: Oxidative stress is a significant contributor to cataract development, underscoring the importance of antioxidants in diagnosis and treatment. Notably, GSH depletion, SOD decline, and lipid peroxidation markers are pivotal factors in cataract pathogenesis, offering promising avenues for both diagnosis and therapeutic intervention.","PeriodicalId":50604,"journal":{"name":"Current Opinion in Ophthalmology","volume":" ","pages":"57-63"},"PeriodicalIF":3.7,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50163515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evidence-based management of optic neuritis. 视神经炎的循证治疗。

IF 3.7 2区医学

Current Opinion in Ophthalmology Pub Date : 2024-01-01 Epub Date: 2023-10-16 DOI: 10.1097/ICU.0000000000001007

Emilie Bergeron, Marc A Bouffard

{"title":"Evidence-based management of optic neuritis.","authors":"Emilie Bergeron, Marc A Bouffard","doi":"10.1097/ICU.0000000000001007","DOIUrl":"10.1097/ICU.0000000000001007","url":null,"abstract":"Purpose of review: Optic neuritis can result from several distinct causes, including multiple sclerosis (MS), neuromyelitis optica spectrum disorder (NMOSD), and myelin oligodendrocyte glycoprotein antibody disease (MOGAD), when not idiopathic. This review discusses evidence-based treatment approaches contingent upon each specific cause of optic neuritis.Recent findings: Current evidence highlights the need for prompt plasmapheresis as adjunct to intravenous methylprednisolone (IVMP) in patients with NMOSD-associated optic neuritis. Recent advances have included a proliferation of novel disease modifying therapies (DMTs) for long-term management of NMOSD and an understanding of how existing therapeutic options can be leveraged to optimally treat MOGAD.Summary: In acute idiopathic or MS-associated optic neuritis, IVMP hastens visual recovery, though it does not substantially affect final visual outcomes. IVMP and adjunctive plasmapheresis are beneficial in the treatment of NMOSD-associated optic neuritis, with a shorter time-to-treatment associated with a higher likelihood of recovery. The natural history of untreated MOGAD-associated optic neuritis is unclear but treatment with IVMP is near-universal given phenotypic similarities with NMOSD. Long-term immunosuppressive therapy is warranted in patients with NMOSD as well as in patients with MOGAD with poor visual recovery or recurrent attacks.","PeriodicalId":50604,"journal":{"name":"Current Opinion in Ophthalmology","volume":" ","pages":"73-82"},"PeriodicalIF":3.7,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41240592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Leber hereditary optic neuropathy gene therapy. Leber 遗传性视神经病变基因疗法。

IF 3.7 2区医学

Current Opinion in Ophthalmology Pub Date : 2023-12-21 DOI: 10.1097/icu.0000000000001028

Byron L Lam

引用次数: 0

Genes as drugs for glaucoma: latest advances. 基因作为治疗青光眼的药物：最新进展。

IF 3.7 2区医学

Current Opinion in Ophthalmology Pub Date : 2023-12-21 DOI: 10.1097/icu.0000000000001025

Teresa Borrás, Michelle Stepankoff, John Danias

引用次数: 0

Glaucoma surgical procedures under development. 正在开发的青光眼手术程序。