Current Opinion in Ophthalmology最新文献_第6页

Immune recovery uveitis: an ocular manifestation in HIV/AIDS receiving treatment. 免疫恢复性葡萄膜炎：接受治疗的艾滋病毒/艾滋病患者的一种眼部表现。

IF 3 2区医学

Current Opinion in Ophthalmology Pub Date : 2024-11-01 Epub Date: 2024-07-16 DOI: 10.1097/ICU.0000000000001078

Martin M Dionson

{"title":"Immune recovery uveitis: an ocular manifestation in HIV/AIDS receiving treatment.","authors":"Martin M Dionson","doi":"10.1097/ICU.0000000000001078","DOIUrl":"10.1097/ICU.0000000000001078","url":null,"abstract":"Purpose of review: This article intends to briefly discuss AIDS, summarize the current literature on immune recovery uveitis, describe its ocular manifestations and complications, and tackle its complex management.Recent findings: The clinical picture of immune recovery uveitis is still evolving. Up to today, there are still no definite criteria for immune recovery uveitis, and although closely associated with cytomegalovirus retinitis and HIV/AIDS, there are several cases of similar intraocular response in non-HIV patients. The exact pathology for this paradoxical inflammatory reaction remains unclear; however, there is an interest in identifying biomarkers to determine underlying mechanisms and identify patients at risk. The management of this disease also remains a challenge and no standardized treatment approach exists currently.Summary: Immune recovery uveitis is an important cause of visual morbidity particularly in HIV/AIDS patients receiving highly active antiretroviral. It is a paradoxical reaction that is frequently associated with a prior cytomegalovirus retinitis infection. Although it can be a transient and self-limiting process, there is a complex decision on the timing of antiviral treatment and the initiation of antiretroviral treatment to prevent immune recovery uveitis. Furthermore, a substantial challenge arises in balancingtreatment decisions for complications in refractory cases.","PeriodicalId":50604,"journal":{"name":"Current Opinion in Ophthalmology","volume":" ","pages":"507-512"},"PeriodicalIF":3.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141753326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ocular involvement in Steven-Johnson syndrome/toxic epidermal necrolysis: recent insights into pathophysiology, biomarkers, and therapeutic strategies. 史蒂文-约翰逊综合征/中毒性表皮坏死症的眼部受累：对病理生理学、生物标记物和治疗策略的最新见解。

IF 3 2区医学

Current Opinion in Ophthalmology Pub Date : 2024-11-01 Epub Date: 2024-08-12 DOI: 10.1097/ICU.0000000000001079

Punyanuch Pisitpayat, Sarayut Nijvipakul, Passara Jongkhajornpong

{"title":"Ocular involvement in Steven-Johnson syndrome/toxic epidermal necrolysis: recent insights into pathophysiology, biomarkers, and therapeutic strategies.","authors":"Punyanuch Pisitpayat, Sarayut Nijvipakul, Passara Jongkhajornpong","doi":"10.1097/ICU.0000000000001079","DOIUrl":"10.1097/ICU.0000000000001079","url":null,"abstract":"Purpose of review: To review the pathophysiology, recent biomarkers related to the ocular aspects of Steven-Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN), and to highlight notable evidence published in recent years.Recent findings: Several studies reveal the relationship between tear cytokines and the pathological components in eyes of SJS/TEN patients. Specific clinical features and associated risk factors in the acute stage have shown significant correlations with chronic ocular sequelae. Recent treatment protocols, including early pulse systemic and topical steroids, as well as tumor necrosis factor-α inhibitors, have demonstrated positive effects on ocular outcomes. In addition to conventional surgical treatment, a new surgical technique, simple oral mucosal epithelial transplantation (SOMET), has been introduced as a simple ocular surface reconstruction for patient with SJS.Summary: Advancements in knowledge and management strategies have notably enhanced ocular outcomes for SJS/TEN eyes. A deeper understanding of the biomarker changes in these eyes could facilitate the development of future targeted treatment options.","PeriodicalId":50604,"journal":{"name":"Current Opinion in Ophthalmology","volume":" ","pages":"499-506"},"PeriodicalIF":3.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141972278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Review and analysis of history and utilization of panretinal photocoagulation and ranibizumab after publication of protocol S. 在 S.方案公布后，对泛视网膜光凝术和雷尼珠单抗的历史和使用情况进行回顾和分析。

IF 3 2区医学

Current Opinion in Ophthalmology Pub Date : 2024-09-01 Epub Date: 2024-07-12 DOI: 10.1097/ICU.0000000000001076

Serena Shah, Brandon Chou, Marissa Patel, Arjun Watane, Lea Shah, Nicolas Yannuzzi, Jayanth Sridhar

{"title":"Review and analysis of history and utilization of panretinal photocoagulation and ranibizumab after publication of protocol S.","authors":"Serena Shah, Brandon Chou, Marissa Patel, Arjun Watane, Lea Shah, Nicolas Yannuzzi, Jayanth Sridhar","doi":"10.1097/ICU.0000000000001076","DOIUrl":"https://doi.org/10.1097/ICU.0000000000001076","url":null,"abstract":"Purpose of review: We describe the history, utilization, and series results of panretinal photocoagulation (PRP) and ranibizumab and provide an analysis of PRP and ranibizumab usage before versus after the publication of the 2-year and 5-year results of the Diabetic Retinopathy Clinical Research Network (DRCR.net) Protocol S trial.Recent findings: Number of ranibizumabs performed began to increase and number of PRPs performed began to decrease in 2016. After publication of the 2-year results, there was significant negative trend in PRP services and significant positive trend in ranibizumab services (both P < 0.001). After publication of the 5-year results, there was significant negative trend in PRP services (P = 0.003). There were significant negative trends (all P < 0.001) in reimbursement factors for PRP from 2013 to 2020: average work RVU (wRVU), nonfacility physical expense RVU, facility PE RVU, malpractice RVU (MP RVU).Summary: Both PRP and ranibizumab have undergone numerous trials comparing their efficacy to other treatment options or no treatment at all. The publication of the 2-year results of Protocol S was associated with an increase in utilization of ranibizumab and decrease in utilization of PRP, with continued decrease after the publication of the 5-year results.","PeriodicalId":50604,"journal":{"name":"Current Opinion in Ophthalmology","volume":"35 5","pages":"369-375"},"PeriodicalIF":3.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141903470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The necessity and role of scleral buckling for rhegmatogenous retinal detachment. 巩膜扣带术治疗流变性视网膜脱离的必要性和作用。

IF 3 2区医学

Current Opinion in Ophthalmology Pub Date : 2024-09-01 Epub Date: 2024-05-31 DOI: 10.1097/ICU.0000000000001065

Kristine Y Wang, Olufemi E Adams, Michael D Yu, Yoshihiro Yonekawa

{"title":"The necessity and role of scleral buckling for rhegmatogenous retinal detachment.","authors":"Kristine Y Wang, Olufemi E Adams, Michael D Yu, Yoshihiro Yonekawa","doi":"10.1097/ICU.0000000000001065","DOIUrl":"10.1097/ICU.0000000000001065","url":null,"abstract":"Purpose of review: With a decline in the use of scleral buckling for rhegmatogenous retinal detachment (RRD) repair in recent years, this review seeks to provide a summary of the most recent research findings regarding the role of scleral buckling in the repair of RRD.Recent findings: Many recent studies have compared visual and anatomic outcomes between scleral buckling and pars plana vitrectomy (PPV) for RRD repair. Some suggest superior outcomes with primary scleral buckling, particularly in younger, phakic patients, and in association with other risk factors that we review. Children do best with primary scleral buckling surgery. Functionally, scleral buckling may also result in lower rates of retinal displacement compared to PPV. When PPV is necessary, a supplemental buckle may benefit certain patients, while the advantage remains unclear in other clinical scenarios and necessitates further investigation.Summary: Scleral buckling is an important technique for the repair of RRD and it is crucial to continue training retina surgeons in this technique to maximize patient outcomes.","PeriodicalId":50604,"journal":{"name":"Current Opinion in Ophthalmology","volume":" ","pages":"376-381"},"PeriodicalIF":3.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141184995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Eco-sustainability in ophthalmology. 眼科的生态可持续性。

IF 3 2区医学

Current Opinion in Ophthalmology Pub Date : 2024-09-01 Epub Date: 2024-06-24 DOI: 10.1097/ICU.0000000000001070

Gabriela G Lee, Matteo Menean, Basil K Williams, Maura Di Nicola

{"title":"Eco-sustainability in ophthalmology.","authors":"Gabriela G Lee, Matteo Menean, Basil K Williams, Maura Di Nicola","doi":"10.1097/ICU.0000000000001070","DOIUrl":"10.1097/ICU.0000000000001070","url":null,"abstract":"Purpose of review: The purpose of this review is to evaluate the current state of eco-sustainability in ophthalmology, highlighting key practices, recent advancements, and areas requiring improvement. This review aims to provide ophthalmologists with a comprehensive overview of sustainable practices that can reduce environmental impact.Recent findings: Recent studies have identified several areas within ophthalmology where sustainable practices can be implemented including multidose eyedrops, adjusting surgical packs, making package inserts available electronically, and reusing surgical instruments. Moreover, there is an increasing emphasis on waste reduction both in the surgical and clinical setting, by decreasing the use of unnecessary materials and implementing more efficient use of recycling programs. Telemedicine has also emerged as a sustainable option, reducing the carbon footprint associated with patient travel. Despite these advancements, significant challenges remain, particularly in balancing the cost and accessibility of sustainable options with traditional practices.Summary: Eco-sustainability in ophthalmology is gaining momentum as the medical community aims to reduce its environmental impact. While progress has been made, further efforts are required to overcome financial and logistical barriers to widespread implementation. Continued research, education, and policy development are essential to advancing eco-sustainable practices, ensuring that environmental considerations become an integral part of ophthalmic care.","PeriodicalId":50604,"journal":{"name":"Current Opinion in Ophthalmology","volume":" ","pages":"403-408"},"PeriodicalIF":3.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141460543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Minimally invasive, maximally impactful: minimally invasive glaucoma surgery and the changing glaucoma landscape. 微创，影响最大：微创青光眼手术和不断变化的青光眼形势。

IF 3 2区医学

Current Opinion in Ophthalmology Pub Date : 2024-09-01 Epub Date: 2024-07-29 DOI: 10.1097/ICU.0000000000001077

Arjun Sharma, Jonathan D Tijerina, Elena Bitrian

引用次数: 0

Treatment for dry age-related macular degeneration: where we stand in 2024. 干性老年性黄斑变性的治疗：2024 年的现状。

IF 3 2区医学

Current Opinion in Ophthalmology Pub Date : 2024-09-01 Epub Date: 2024-06-13 DOI: 10.1097/ICU.0000000000001064

Sydney Wheeler, Raziyeh Mahmoudzadeh, Jessica Randolph

{"title":"Treatment for dry age-related macular degeneration: where we stand in 2024.","authors":"Sydney Wheeler, Raziyeh Mahmoudzadeh, Jessica Randolph","doi":"10.1097/ICU.0000000000001064","DOIUrl":"10.1097/ICU.0000000000001064","url":null,"abstract":"Purpose of review: This review highlights treatment options, both under investigation and currently available, for the treatment of dry age-related macular degeneration (AMD). An update on current clinical studies for dry AMD has been summarized.Recent findings: Advanced dry AMD, characterized by geographic atrophy (GA), is a leading cause of blindness in the developed world, though prior to 2023 there was no approved treatment. There are now two approved treatments in the United States for GA. Additionally, there are several studies and trials to investigate therapeutic potential and effects of therapies for earlier intervention in dry AMD. Approaches to therapy include inhibiting the complement system, utilizing gene therapy, stem cell therapy, laser therapy, and surgical implants.Summary: While there has been notable prior advancement in the treatment for neovascular or wet AMD, for the first time there are Food and Drug Administration (FDA) approved treatments for GA. Clinical studies have shown promise for additional methods for managing dry AMD both medically and surgically.","PeriodicalId":50604,"journal":{"name":"Current Opinion in Ophthalmology","volume":" ","pages":"359-364"},"PeriodicalIF":3.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141318909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Criteria for premium intraocular lens patient selection. 选择优质眼内透镜患者的标准。

IF 3 2区医学

Current Opinion in Ophthalmology Pub Date : 2024-09-01 Epub Date: 2024-06-13 DOI: 10.1097/ICU.0000000000001067

Jacqueline L Chen, Zaina N Al-Mohtaseb, Allison J Chen

引用次数: 0

The role of oculoplastic surgeons in minimally invasive cosmetic injectables. 眼部整形外科医生在微创注射美容中的作用。

IF 3 2区医学

Current Opinion in Ophthalmology Pub Date : 2024-09-01 Epub Date: 2024-06-27 DOI: 10.1097/ICU.0000000000001068

Elana Meer, Jacqueline Lopez, Jonathan Lu, Bryan J Winn, Seanna R Grob

{"title":"The role of oculoplastic surgeons in minimally invasive cosmetic injectables.","authors":"Elana Meer, Jacqueline Lopez, Jonathan Lu, Bryan J Winn, Seanna R Grob","doi":"10.1097/ICU.0000000000001068","DOIUrl":"10.1097/ICU.0000000000001068","url":null,"abstract":"Purpose of review: In recent years, the field of aesthetic medicine has witnessed a paradigm shift with an increasing demand for minimally invasive cosmetic procedures, including cosmetic injectables. This review aims to delineate the distinctive role played by oculoplastic surgeons in the administration of cosmetic injectables, comparing their expertise to that of nonphysician practitioners.Recent findings: Complications arising from cosmetic injections are discussed, including skin discoloration, inflammation, necrosis, vision loss, retinal pathology, and central nervous system adverse effects. Injector expertise, patient factors, type of filler, location of injection, and management strategies are reviewed. Findings highlight diverse practitioner involvement, common adverse effects like skin necrosis and vision loss, with hyaluronic acid fillers being prominent. Areas at the highest risk for ocular complication include the glabella and nose with potential management involving dissolving fillers and reducing pressure. Emphasis is placed on expert injector selection and patient awareness.Summary: The administration of cosmetic injectables requires a profound understanding of facial anatomy, vasculature, and potential complications. In contrast to nonphysician practitioners, oculoplastic and aesthetic surgeons bring a level of anatomical precision and clinical acumen that is essential for navigating the complexities of cosmetic injectables. Emphasis on training and collaboration among practitioners will be essential in advancing the field while prioritizing patient safety and satisfaction.","PeriodicalId":50604,"journal":{"name":"Current Opinion in Ophthalmology","volume":" ","pages":"382-390"},"PeriodicalIF":3.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141460545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Management of vitreous floaters: a review. 玻璃体漂浮物的处理：综述。

IF 3 2区医学

Current Opinion in Ophthalmology Pub Date : 2024-09-01 Epub Date: 2024-07-11 DOI: 10.1097/ICU.0000000000001075

Alexis Ivan Aleman, Lauren Kiryakoza, Jayanth Sridhar, Jesse Sengillo

{"title":"Management of vitreous floaters: a review.","authors":"Alexis Ivan Aleman, Lauren Kiryakoza, Jayanth Sridhar, Jesse Sengillo","doi":"10.1097/ICU.0000000000001075","DOIUrl":"10.1097/ICU.0000000000001075","url":null,"abstract":"Purpose of review: Vitreous floaters, characterized by the perception of spots or shadows in the visual field, commonly result from posterior vitreous detachment and can cause chronic symptoms in affected patients. The diagnosis of posterior vitreous detachment is typically determined clinically and can sometimes be confirmed with optical coherence topography (OCT) [1 ▪▪ ] . The objective of this review is to review management options for symptomatic vitreous floaters.Recent findings: Symptoms of vitreous floaters may be mild or may significantly affect patient quality of life. Observation is the most common management strategy. Procedural management options include pars plana vitrectomy (PPV) and neodymium-doped yttrium aluminium garnet (Nd:YAG) vitreolysis. PPV is considered the most definitive management option for vitreous floaters. PPV, however, carries inherent risks, notably infection, cataract formation, and retinal detachment [2] . Nd:YAG laser vitreolysis is a less invasive alternative with studies demonstrating varied success [1 ▪▪ ,3,4] .Summary: This review provides insights into the current state of knowledge regarding the management of vitreous floaters and can guide clinical decision-making.","PeriodicalId":50604,"journal":{"name":"Current Opinion in Ophthalmology","volume":" ","pages":"365-368"},"PeriodicalIF":3.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141753327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0