Developmental Medicine and Child Neurology最新文献

{"title":"Shedding light on a highly complex causal network in cerebral palsy","authors":"Luigi Gagliardi","doi":"10.1111/dmcn.70322","DOIUrl":"10.1111/dmcn.70322","url":null,"abstract":"<p><b>This commentary is on the original article by Goldsmith et al. on pages</b> 1593–1599 <b>of this issue.</b></p>","PeriodicalId":50587,"journal":{"name":"Developmental Medicine and Child Neurology","volume":"68 11","pages":"1497-1498"},"PeriodicalIF":3.7,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148007318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cognition in adults with cerebral palsy: A systematic review","authors":"Kanishka Baduni,&nbsp;Brittany Perry,&nbsp;Seth Warschausky,&nbsp;Nathalie L. Maitre,&nbsp;The Adult CP Clinical Practice Guideline Working Group","doi":"10.1111/dmcn.70280","DOIUrl":"10.1111/dmcn.70280","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>To synthesize evidence on cognitive functioning in adults with cerebral palsy (CP), evaluate the feasibility and validity of cognitive screens, determine whether cognitive functioning declines with age, identify factors associated with cognitive outcomes, and summarize interventions reporting cognitive outcomes.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Method</h3>\u0000 \u0000 <p>Five databases were searched through 2025. Eligible studies enrolled adults with CP and reported cognitive outcomes. Two reviewers screened and extracted data; quality was appraised with JBI tools and certainty graded using Grading of Recommendations Assessment, Development and Evaluation (GRADE). Findings were synthesized narratively according to cognitive domain.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Thirty studies (estimated 1150 adults, 3900 assessments) were included. Executive function, and visuospatial and perceptual-motor skills, were most frequently impaired. Attention and processing speed and episodic memory were also commonly reduced. Certainty was moderate for executive function and very low for other domains because of small samples, bias, inconsistency, and imprecision. Longitudinal and registry data suggested stability from late adolescence through mid-adulthood. Greater motor severity and reduced manual ability were associated with lower cognitive performance. No motor-minimized, CP-validated screening battery was identified across 48 instruments.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Interpretation</h3>\u0000 \u0000 <p>Adults with CP commonly show domain-specific cognitive difficulties that are established early and remain stable through mid-adulthood. Measurement limitations and selection biases constrain prevalence estimates. Priorities include motor-minimized tools with CP-specific norms, adequately powered trials with standardized cognitive endpoints, and longitudinal cohorts examining modifiable factors.</p>\u0000 </section>\u0000 </div>","PeriodicalId":50587,"journal":{"name":"Developmental Medicine and Child Neurology","volume":"68 11","pages":"1525-1537"},"PeriodicalIF":3.7,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147718847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exoskeleton-assisted physiotherapy in school and outpatient contexts for minimally ambulant children with cerebral palsy","authors":"Stefanie S. Bradley,&nbsp;Tom Chau,&nbsp;Anne Kawamura,&nbsp;F. Virginia Wright","doi":"10.1111/dmcn.70212","DOIUrl":"10.1111/dmcn.70212","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>To assess the clinical feasibility of lower-limb pediatric exoskeleton-assisted (Trexo Plus) physiotherapy for minimally ambulatory children at an outpatient center and a primary school. Secondary aims were to assess associated functional and goal-based outcomes before and after Trexo-based physiotherapy.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Method</h3>\u0000 \u0000 <p>Ten children with cerebral palsy participated (five males; mean age 5 years 9 months; Gross Motor Function Classification System level IV). Trexo intervention (twice weekly for 6 weeks) was provided in school (gym class/individual physiotherapy) and outpatient (individual physiotherapy) settings by a physiotherapist two-person team. Independent physiotherapy (motor/functional) assessments occurred pre-intervention, 1-week post-intervention, and 5-weeks post-intervention.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Fifteen of 16 clinical feasibility indicators were met. Every participant completed the intervention and Trexo use was found to be safe (two adverse skin events in one child). Children reported high enjoyment and comfort during Trexo-facilitated activities, and exercise-linked fatigue. Canadian Occupational Performance Measure and Goal Attainment Scale functional goals were achieved overall, but there was no meaningful increase in Gross Motor Function Measure (88 items; mean change +1.0). Gait assessments showed no increase in 1-minute walk distance but did show enhanced gait maneuverability and reduced physiotherapist assistance when children used their supported-stepping walker.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Interpretation</h3>\u0000 \u0000 <p>Exoskeleton-based therapy was safe, feasible, and associated with achieving Trexo intervention-focused goals in school and outpatient settings with physiotherapist team support.</p>\u0000 </section>\u0000 </div>","PeriodicalId":50587,"journal":{"name":"Developmental Medicine and Child Neurology","volume":"68 11","pages":"1580-1592"},"PeriodicalIF":3.7,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/dmcn.70212","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147379527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Insights from clinical utility studies on rehabilitation technologies for therapy and research","authors":"Hubertus J. A. van Hedel","doi":"10.1111/dmcn.70249","DOIUrl":"10.1111/dmcn.70249","url":null,"abstract":"&lt;p&gt;Independent mobility enables children to explore their environments, engage in play, and develop relationships with peers at home, in school, and during leisure activities. Children with early-onset disabilities such as cerebral palsy (CP) may experience mobility challenges. Powered mobility interventions can enhance not only mobility but also participation, play, and social interactions for these children.&lt;span&gt;&lt;sup&gt;1&lt;/sup&gt;&lt;/span&gt; Early provision of mobility support may therefore positively influence multiple domains described by the F-words framework.&lt;span&gt;&lt;sup&gt;2&lt;/sup&gt;&lt;/span&gt; Whereas powered mobility was previously associated primarily with powered wheelchairs, recent innovations such as the Trexo now enable children with disabilities to walk and interact with peers at eye level.&lt;/p&gt;&lt;p&gt;Trexo was initially developed as an assistive technology to compensate for impairments and enhance the participation of children with disabilities in family and community settings. Bradley et al. have now examined its feasibility as a rehabilitation therapy device, that is, to improve function.&lt;span&gt;&lt;sup&gt;3&lt;/sup&gt;&lt;/span&gt; Although the authors may have demonstrated some overenthusiasm in their small-sample study, given the inclusion of multiple factors and diverse contexts, their work is commendable, as research involving technologies for children with severe impairments, such as 4- to 7-year-old participants in Gross Motor Function Classification System level IV, presents significant challenges.&lt;/p&gt;&lt;p&gt;The personalized application of new technology requires assessment of its robustness, user acceptance among therapists and patients, and its specific effects. Understanding how children with sensorimotor and cognitive impairments respond to the technology is essential for identifying potential changes in body functions. If repeated exposure to the technology results in functional improvements over time, appropriate therapeutic goals can be established. Feasibility and clinical utility studies offer preliminary insights into these considerations.&lt;/p&gt;&lt;p&gt;Smart identified four components of clinical utility relevant to the implementation of healthcare technology: appropriateness, practicability, acceptability, and accessibility.&lt;span&gt;&lt;sup&gt;4&lt;/sup&gt;&lt;/span&gt; Bradley et al. addressed each of these components in their study.&lt;/p&gt;&lt;p&gt;Appropriateness encompasses the technology's effectiveness and its potential impact on the existing treatment process. The findings of Bradley et al. indicate that while certain therapeutic goals may be achieved, walking ability may not show substantial improvement. Upcoming analyses of leg muscle activation and heart rate might clarify whether Trexo increases physical activity in these children.&lt;/p&gt;&lt;p&gt;Practicability concerns whether the materials and methods function effectively in real-world settings. This aspect was thoroughly evaluated, though the study environment may not fully replicate actual clinical conditions, as noted by the authors. The r","PeriodicalId":50587,"journal":{"name":"Developmental Medicine and Child Neurology","volume":"68 11","pages":"1496-1497"},"PeriodicalIF":3.7,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/dmcn.70249","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147437211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adapted physical activity to enable participation of children and adolescents with disabilities","authors":"Kwok Ng","doi":"10.1111/dmcn.70455","DOIUrl":"10.1111/dmcn.70455","url":null,"abstract":"&lt;p&gt;The benefits of physical activity for children and adolescents, including those with disabilities, are well established. Adapted physical activity (APA) has evolved as a cross-disciplinary field that combines scientific knowledge with practical approaches to increase participation among people with impairments, activity limitations, and participation restrictions (https://ifapa.net/what-is-apa).&lt;span&gt;&lt;sup&gt;1&lt;/sup&gt;&lt;/span&gt; Yet, how can we make meaningful participation possible for every child?&lt;/p&gt;&lt;p&gt;Successful APA programmes demonstrate that participation depends on much more than the ‘exercise itself’. Family-led initiatives illustrate how co-designed community programmes can create opportunities for play and inclusion (e.g. https://www.maemurrayfoundation.org/). Community rehabilitation models emphasize continuity by linking individualized goal setting conducted before an intensive healthsport centre intervention and long-term follow-up in the child's everyday environment (https://www.bhss.no/en). Research-based programmes, such as FitSkills,&lt;span&gt;&lt;sup&gt;2&lt;/sup&gt;&lt;/span&gt; show that structured partnerships between disabled children and trained student mentors can simultaneously promote fitness, confidence, and social connectedness. Although different in design, these approaches share a common principle: participation is created through collaboration between children, families, professionals, and communities. They also demonstrate that meaningful physical activity is rarely the product of a single intervention, but more often emerges from coordinated efforts across healthcare, education, sport, and community sectors.&lt;/p&gt;&lt;p&gt;Current World Health Organization physical activity guidelines recommend an average of 60 minutes of moderate-to-vigorous physical activity per day across the week, together with muscle-strengthening activities at least three times per week.&lt;span&gt;&lt;sup&gt;3&lt;/sup&gt;&lt;/span&gt; These recommendations provide important public health benchmarks but they may appear unattainable for many disabled children and their families. When recommendations seem unrealistic, they risk becoming discouraging rather than motivating. By contrast, evidence underpinning the UK Chief Medical Officer's recommendations suggests that an average of 20 minutes per day may represent a more realistic starting point for many children with cerebral palsy.&lt;span&gt;&lt;sup&gt;4&lt;/sup&gt;&lt;/span&gt;&lt;/p&gt;&lt;p&gt;Equally important, the accompanying co-designed messages encourage children to build activity gradually, accumulate it in manageable bouts, make it appropriately challenging, and recognize that even small amounts of physical activity are worthwhile.&lt;/p&gt;&lt;p&gt;This apparently subtle distinction reflects an important shift in perspective. Rather than asking whether children meet guideline targets, a more relevant question may be whether they are becoming more active than they were before (i.e. progress may be a meaningful measure of success). Such an approach aligns more closely with individualized, p","PeriodicalId":50587,"journal":{"name":"Developmental Medicine and Child Neurology","volume":"68 11","pages":"1490-1491"},"PeriodicalIF":3.7,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/dmcn.70455","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148632506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Weight measurements and disease-specific growth charts to predict clinical outcomes in children with cerebral palsy","authors":"Judy-April O. Murayi,&nbsp;Laurie J. Glader,&nbsp;Richard D. Stevenson,&nbsp;Carson J. Richardson,&nbsp;Praveen S. Goday","doi":"10.1111/dmcn.70204","DOIUrl":"10.1111/dmcn.70204","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>To determine whether weight-for-age (WFA) centiles on disease-specific growth charts predict clinical outcomes in children with cerebral palsy (CP).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Method</h3>\u0000 \u0000 <p>We conducted a retrospective cohort study of pediatric patients with CP in Gross Motor Function Classification System levels III to V, treated at a tertiary care hospital from January 2016 to June 2022. Patients were categorized as above or below the 20th centile WFA using CP-specific growth curves. Clinical outcomes included emergency department and urgent care visits, hospital and pediatric intensive care unit (PICU) admissions, fracture incidence, surgical procedures, and mortality.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Of 127 patients (62.9% male, age range at study entry 3–20 years; mean age 10 years 7 months, SD 4 years 5 months), 113 were above and 14 were below the 20th centile. The ‘below’ group had a 122% higher mean number of emergency department and urgent care visits than the ‘above’ group (<i>p</i> = 0.004, adjusted incidence rate ratio: 2.22; 95% confidence interval: 1.29, 3.8). They also had a median 1.5 more PICU admissions and 5.2 longer PICU days compared to the ‘above’ group. Mortality was 4.4% (5/113) in the ‘above’ group and 28.6% (4/14) in the ‘below’ group.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Interpretation</h3>\u0000 \u0000 <p>Children with CP who fall below the 20th centile WFA appear to require more healthcare services and may face increased mortality risk. Maintaining WFA above the 20th centile may represent an important clinical target.</p>\u0000 </section>\u0000 </div>","PeriodicalId":50587,"journal":{"name":"Developmental Medicine and Child Neurology","volume":"68 11","pages":"1561-1569"},"PeriodicalIF":3.7,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147322606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-term respiratory support in cerebral palsy: Defining benefit beyond physiological change","authors":"Monica S. Cooper","doi":"10.1111/dmcn.70315","DOIUrl":"10.1111/dmcn.70315","url":null,"abstract":"&lt;p&gt;Respiratory disease remains a major contributor to morbidity and mortality in the population with cerebral palsy (CP).&lt;span&gt;&lt;sup&gt;1&lt;/sup&gt;&lt;/span&gt; Sleep-disordered breathing and awake respiratory symptoms are potentially modifiable contributors to this.&lt;span&gt;&lt;sup&gt;2, 3&lt;/sup&gt;&lt;/span&gt; Obstructive, restrictive, and central mechanisms often coexist, reflecting underlying physiological complexity,&lt;span&gt;&lt;sup&gt;4&lt;/sup&gt;&lt;/span&gt; with differing implications for management and prognosis. Management is further shaped by treatment-related factors, including effects of positive airway pressure on upper airway dynamics, medications that alter tone or respiratory drive, and the contribution of reflux and aspiration. Respiratory support is, therefore, introduced within a heterogeneous and dynamic pathophysiological context.&lt;span&gt;&lt;sup&gt;4&lt;/sup&gt;&lt;/span&gt;&lt;/p&gt;&lt;p&gt;Dhandayuthapani et al. examine this important area in their paper.&lt;span&gt;&lt;sup&gt;5&lt;/sup&gt;&lt;/span&gt; The authors synthesize what is available from a limited and heterogeneous evidence base. Outcome domains span physiological measures, sleep quality, treatment tolerance, and caregiver quality of life. Some consistent signals emerge. Respiratory support can stabilize sleep-related physiological parameters, although the certainty of evidence remains low. There is some caregiver benefit. However, key outcomes remain underrepresented; there is little evidence addressing hospital admissions, infection, or direct measures of child quality of life, limiting understanding beyond physiological change. More fundamentally, the limitations raise a broader question: not whether respiratory support improves physiological parameters, but how benefit should be defined and prioritized.&lt;/p&gt;&lt;p&gt;The use of non-invasive respiratory support, including continuous positive airway pressure (CPAP) and bilevel ventilation, as well as invasive ventilation via tracheostomy, is increasing.&lt;span&gt;&lt;sup&gt;4&lt;/sup&gt;&lt;/span&gt; Its role has also gained prominence as societal expectations have shifted. Families increasingly expect access to these interventions and, in well-resourced health systems, long-term respiratory support is more readily available, bolstered by community nursing and overnight care. Clinical experience suggests that non-invasive respiratory support can enable earlier discharge from hospital and improve physiological stability. However, it also redistributes elements of intensive care into the home environment, increasing caregiving demands, and may extend survival in the context of significant multimorbidity. For some children, this may represent meaningful stabilization and improved quality of life; for others, it may prolong exposure to ongoing symptoms and high treatment burden without clear functional gain. This highlights a fundamental tension between physiological benefit and lived burden. Improvements in sleep study indices, while relevant, may not necessarily translate to comfort, improved daily function, reduced healthcare utilization, or sus","PeriodicalId":50587,"journal":{"name":"Developmental Medicine and Child Neurology","volume":"68 11","pages":"1492-1493"},"PeriodicalIF":3.7,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/dmcn.70315","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147934625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The F-words for childhood development in community-based physical activity programmes for children with physical disabilities: A scoping review","authors":"Belinda Munroe,&nbsp;Sarah Ashcroft,&nbsp;Suzanne Lock,&nbsp;Kylie Turner,&nbsp;Belinda Arnold,&nbsp;Sarah Reedman","doi":"10.1111/dmcn.70306","DOIUrl":"10.1111/dmcn.70306","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>To identify intervention ingredients used to address the F-words for childhood development in community-based physical activity programmes for children with physical disabilities, the programme outcomes, and the strength of available evidence.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Method</h3>\u0000 \u0000 <p>A scoping review was conducted guided by the JBI Manual for Evidence Synthesis. Electronic database and hand searches of international literature identified studies that evaluated community-based physical activity programmes for children with a physical disability with impaired gross motor skills (e.g. sitting, walking) ranging from mild limitations in speed, balance, and coordination to severe impairment requiring the use of a wheelchair for mobility. Intervention ingredients were mapped to the six F-words: functioning, fitness, friends, family, fun, and future. Primary study outcomes were tallied and themed. Evidence strength was assessed using the Australian National Health and Medical Research Council guidelines and the Risk of Bias in Non-randomised Studies - of Interventions (ROBINS-I) tool.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Twenty-four primary research articles were included. Most studies addressed the concept of functioning, fitness, fun, and friends, and few studies addressed family and future. Thirty common intervention ingredients were identified to deliver the F-words. Eight key outcome areas were identified. Most studies were level IV evidence and possessed a serious level of bias.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Interpretation</h3>\u0000 \u0000 <p>Despite identifying numerous intervention ingredients mapped to the F-words, the overall evidence base remains weak. Strengthening the quality and scope of research is essential to ensure the F-words framework is applied inclusively for physical activities across diverse populations of children with physical disabilities in community contexts.</p>\u0000 </section>\u0000 </div>","PeriodicalId":50587,"journal":{"name":"Developmental Medicine and Child Neurology","volume":"68 11","pages":"1501-1513"},"PeriodicalIF":3.7,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/dmcn.70306","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147876446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Outcomes of children and young people with cerebral palsy receiving long-term respiratory support: A systematic review","authors":"Rajkumar Dhandayuthapani,&nbsp;Alasdair Campbell,&nbsp;Catherine M McDougall,&nbsp;Florian Gahleitner,&nbsp;Steve Cunningham,&nbsp;Don S Urquhart","doi":"10.1111/dmcn.70279","DOIUrl":"10.1111/dmcn.70279","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>To systematically review the current knowledge gap in, and impact of, long-term respiratory support in children and young people (CYP) with cerebral palsy (CP).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Method</h3>\u0000 \u0000 <p>We searched six databases from inception until 30th January 2025. Grey literature was also searched. Screening and data extraction using Covidence software, quality of evidence (Risk Of Bias In Non-randomized Studies - of Interventions), and certainty of evidence (Grading of Recommendation, Assessment, Development and Evaluation) grading were independently conducted by two reviewers, with a third reviewer resolving any lack of consensus.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Title and abstract screening (<i>n</i> = 1994) and full-text reviews (<i>n</i> = 45) identified four studies (with moderate to severe risk of bias) for data extraction. Findings presented as a narrative synthesis from vote counting suggest improvement in sleep study parameters for CYP with CP on long-term respiratory support and quality of life for their parents (low certainty of evidence).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Interpretation</h3>\u0000 \u0000 <p>This review identified a significant knowledge gap in the use of long-term respiratory support in CYP with CP and its impact on health-related outcomes for such young people. This limits the information that can be offered when counselling parents/carers before initiating respiratory support in CYP with CP. Further research is needed to allow better service-planning at national and local levels.</p>\u0000 </section>\u0000 </div>","PeriodicalId":50587,"journal":{"name":"Developmental Medicine and Child Neurology","volume":"68 11","pages":"1514-1524"},"PeriodicalIF":3.7,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/dmcn.70279","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147787590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Building the evidence base for pediatric vertigo guidelines.","authors":"Joshua Gurberg","doi":"10.1111/dmcn.70551","DOIUrl":"https://doi.org/10.1111/dmcn.70551","url":null,"abstract":"","PeriodicalId":50587,"journal":{"name":"Developmental Medicine and Child Neurology","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2026-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149117827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}