Developmental Medicine and Child Neurology最新文献_第10页

Combined dorsal and ventral rhizotomy in non-ambulatory individuals with mixed spastic bilateral cerebral palsy: A prospective registry analysis. 联合背侧和腹侧神经根切断术治疗混合性痉挛性双侧脑瘫患者：一项前瞻性登记分析。

IF 3.7 2区医学

Developmental Medicine and Child Neurology Pub Date : 2026-09-30 DOI: 10.1111/dmcn.70556

引用次数: 0

Concerns about paracetamol during pregnancy: Precaution or paranoia? 怀孕期间对扑热息痛的担忧：预防还是偏执？

IF 3.7 2区医学

Developmental Medicine and Child Neurology Pub Date : 2026-09-30 DOI: 10.1111/dmcn.70537

Alycia Halladay

引用次数: 0

Global clinical practice frameworks needed for child-to-adult transition in rare neurological disorders. 罕见神经系统疾病儿童向成人过渡所需的全球临床实践框架。

IF 3.7 2区医学

Developmental Medicine and Child Neurology Pub Date : 2026-09-30 DOI: 10.1111/dmcn.70517

Lakshmi Nagarajan

引用次数: 0

International recommendations for child to adult care transition in rare neurological diseases: A scoping review and Delphi consensus study. 罕见神经系统疾病从儿童到成人护理过渡的国际建议：范围综述和德尔菲共识研究。

IF 3.7 2区医学

Developmental Medicine and Child Neurology Pub Date : 2026-09-30 DOI: 10.1111/dmcn.70499

Lucie Stovickova, Riccardo Ronco, Sylvia Boesch, Enrico Bertini, Mary Kearney, Lidia Sarro, Juan Darío Ortigoza-Escobar, Sophie Ripp, Caterina Mariotti

{"title":"International recommendations for child to adult care transition in rare neurological diseases: A scoping review and Delphi consensus study.","authors":"Lucie Stovickova, Riccardo Ronco, Sylvia Boesch, Enrico Bertini, Mary Kearney, Lidia Sarro, Juan Darío Ortigoza-Escobar, Sophie Ripp, Caterina Mariotti","doi":"10.1111/dmcn.70499","DOIUrl":"https://doi.org/10.1111/dmcn.70499","url":null,"abstract":"Aim: To produce recommendations for specific neurological diseases, including ataxias, hereditary spastic paraplegias, leukodystrophies, dystonias, and choreas.Method: Our study consisted of two related phases. First, we conducted a scoping review to identify essential elements of transitional care models. These elements were included in a questionnaire that was subsequently evaluated by an international group of experts using a modified web-based Delphi consensus process. Results were analysed according to the RAND/UCLA methodology.Results: Fifty-nine statements of transitional care were evaluated by 47 health care specialists from 12 countries. Panellists were experts in ataxias (n = 12), hereditary spastic paraplegias (n = 10), leukodystrophies (n = 9), choreas (n = 7), and dystonias (n = 9). Seventeen recommendations met consensus in all five disease categories.Interpretation: Child-to-adult transition has been investigated in many fields of medicine; however, only few reports have considered rare neurological disorders. The transition working group of the European Reference Network for Rare Neurological Diseases has proposed a collaborative effort to produce recommendations for specific neurological diseases. The recommendations identified in our study reflect areas of shared priorities across multiple disease groups of rare neurological diseases and provide an essential level of guidance to support clinicians and families in promoting consistent transition projects of care across centres with different health care systems.","PeriodicalId":50587,"journal":{"name":"Developmental Medicine and Child Neurology","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2026-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149117882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

What would universal screening for cerebral palsy be worth? The case for net benefit analysis. 脑瘫的普遍筛查有什么价值？净效益分析的案例。

IF 3.7 2区医学

Developmental Medicine and Child Neurology Pub Date : 2026-09-29 DOI: 10.1111/dmcn.70553

Giovanni Briganti, Richard J McNally

引用次数: 0

Attention-deficit/hyperactivity disorder in neurofibromatosis type 1. 1型神经纤维瘤病的注意缺陷/多动障碍。

IF 3.7 2区医学

Developmental Medicine and Child Neurology Pub Date : 2026-09-29 DOI: 10.1111/dmcn.70555

引用次数: 0

Muscle tone and pain in children with spastic cerebral palsy. 痉挛型脑瘫患儿的肌张力与疼痛。

IF 3.7 2区医学

Developmental Medicine and Child Neurology Pub Date : 2026-09-29 DOI: 10.1111/dmcn.70548

Olav Aga Kildal, Sandra Julsen Hollung, Keson Jaioun, Guro L Andersen

{"title":"Muscle tone and pain in children with spastic cerebral palsy.","authors":"Olav Aga Kildal, Sandra Julsen Hollung, Keson Jaioun, Guro L Andersen","doi":"10.1111/dmcn.70548","DOIUrl":"https://doi.org/10.1111/dmcn.70548","url":null,"abstract":"Aim: To investigate associations between muscle tone measured using the Modified Ashworth Scale (MAS) and pain in children with spastic cerebral palsy (CP).Method: Children (aged 0-17 years; mean age 10 years 2 months) in the Norwegian Quality and Surveillance Registry for Cerebral Palsy with physical therapy assessments between 2018 and 2021 were included (n = 1188; 42.3% female) in this population-based cross-sectional study. Logistic regression analyses were used to examine the association between MAS scores and pain. Odds ratios (ORs) with 95% confidence intervals (CIs) were reported.Results: Pain was experienced by 41.4% (n = 492). Risk of pain was highest in children classified in Gross Motor Function Classification System level V (OR = 1.81, 95% CI = 1.21-2.70) and Manual Ability Classification System level V (OR = 2.00, 95% CI = 1.25-3.16), children with bilateral spastic CP (OR = 1.34, 95% CI = 1.06-1.68) and increasing age (OR = 1.12, 95% CI = 1.09-1.15). Pain interfered with sleep in 24.8% (n = 122) of children and activities of daily living (ADLs) in 53.0% (n = 261) of children. An MAS score of 2 or greater was recorded in 42.3% (n = 502), most often in the ankle plantar flexors. Adjusted analyses showed that the highest MAS score was associated with pain interfering with ADLs (adjusted OR = 1.40, 95% CI = 1.00-1.96), and an MAS score of 2 or greater with higher pain intensity (adjusted OR = 1.2, 95% CI = 1.01-1.42).Interpretation: Pain is common in children with spastic CP, frequently disrupting sleep and ADLs. Higher MAS scores are modestly associated with increased pain intensity and interference, highlighting the need for targeted pain screening strategies.","PeriodicalId":50587,"journal":{"name":"Developmental Medicine and Child Neurology","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2026-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149076610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The complexity of back pain in adults with cerebral palsy: Focus on function. 成人脑瘫患者背部疼痛的复杂性：关注功能。

IF 3.7 2区医学

Developmental Medicine and Child Neurology Pub Date : 2026-09-29 DOI: 10.1111/dmcn.70554

Cristina Sarmiento

引用次数: 0

Measuring muscle tone and pain in children with cerebral palsy: Pain that does not interfere is still pain. 测量脑瘫儿童的肌肉张力和疼痛：不干扰的疼痛仍然是疼痛。

IF 3.7 2区医学

Developmental Medicine and Child Neurology Pub Date : 2026-09-29 DOI: 10.1111/dmcn.70545

Sarah Kim, Edward Hurvitz

引用次数: 0

Blood pressure and transcranial ultrasound predict moyamoya vasculopathy in Down syndrome. 血压和经颅超声预测唐氏综合征烟雾病。

IF 3.7 2区医学

Developmental Medicine and Child Neurology Pub Date : 2026-09-29 DOI: 10.1111/dmcn.70552

Jonathan D Santoro, Mackenzie Silverman, Benjamin N Vogel, Bryan T Lei, Ramon Durazo-Arvizu, Sarah Lee, Elizabeth W Mayne, Brian G Skotko, Pat Levitt, Michael S Rafii

{"title":"Blood pressure and transcranial ultrasound predict moyamoya vasculopathy in Down syndrome.","authors":"Jonathan D Santoro, Mackenzie Silverman, Benjamin N Vogel, Bryan T Lei, Ramon Durazo-Arvizu, Sarah Lee, Elizabeth W Mayne, Brian G Skotko, Pat Levitt, Michael S Rafii","doi":"10.1111/dmcn.70552","DOIUrl":"10.1111/dmcn.70552","url":null,"abstract":"Aim: To evaluate the feasibility of a stepwise, non-invasive screening framework integrating blood pressure measurement with transcranial Doppler ultrasonography.Method: In this prospective single-site cohort study, 793 individuals with Down syndrome aged 8 to 26 years underwent standardized blood pressure assessment. Comparisons with National Health and Nutrition Examination Survey 2017-2018 were restricted to participants aged 8 years to younger than 18 years and performed using survey-weighted regression. A smaller cohort of 111 participants underwent repeat blood pressure assessment, awake transcranial Doppler ultrasonography, and confirmatory magnetic resonance imaging/angiography.Results: Among 988 screened participants, 793 were enrolled (mean age 16 years 7 months [SD 4 years 6 months]; 414 females, 378 males, and one participant of unknown sex). Mean systolic blood pressure centile was 44.7 in Down syndrome and 42.6 in the comparison cohort (difference 2.07 points, 95% confidence interval [CI] -1.12 to 5.26; p = 0.200). Diastolic blood pressure centile was higher in Down syndrome (difference 12.21 points, 95% CI 8.88-15.53; p < 0.001). Of the 111 participants who completed transcranial Doppler ultrasonography, 10 required repeat acquisition. Higher blood pressure was associated with higher mean middle cerebral artery velocity (75.5 vs 65.7 cm/s; p = 0.006). Imaging identified asymptomatic moyamoya syndrome in four participants.Interpretation: A stepwise approach incorporating blood pressure and transcranial Doppler ultrasonography is feasible for cerebrovascular surveillance in Down syndrome. These findings support development of scalable screening strategies and warrant multicenter validation.","PeriodicalId":50587,"journal":{"name":"Developmental Medicine and Child Neurology","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2026-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149082812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0