European Journal of Contraception and Reproductive Health Care最新文献

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A pilot randomised study to compare sub-lingual and vaginal routes of low-dose misoprostol following two sequential doses of mifepristone for second-trimester medical abortion. 一项试点随机研究,比较在连续两次米非司酮治疗中期妊娠药物流产后低剂量米索前列醇的舌下和阴道途径。
IF 1.9 4区 医学
European Journal of Contraception and Reproductive Health Care Pub Date : 2025-02-13 DOI: 10.1080/13625187.2025.2452178
Pavithra Justa, Rashmi Bagga, Anil E, Subhas Chandra Saha, Jaswinder Kalra, Vanita Jain, Aashima Arora
{"title":"A pilot randomised study to compare sub-lingual and vaginal routes of low-dose misoprostol following two sequential doses of mifepristone for second-trimester medical abortion.","authors":"Pavithra Justa, Rashmi Bagga, Anil E, Subhas Chandra Saha, Jaswinder Kalra, Vanita Jain, Aashima Arora","doi":"10.1080/13625187.2025.2452178","DOIUrl":"https://doi.org/10.1080/13625187.2025.2452178","url":null,"abstract":"<p><strong>Primary objective: </strong>A randomized study to compare the induction abortion interval (IAI) using two different routes of Low-dose misoprostol administration Sublingual (S/L) and vaginal, after priming with two sequential doses of mifepristone for second-trimester medical abortion.</p><p><strong>Study design: </strong>After randomization in two groups, participants received two doses of mifepristone (200 mg) 24 h apart. On day 3, 200mcg of misoprostol was given by S/L route to group 1 and by vaginal route to group 2, (400mcg among women with gestation ≤16 weeks) and every 6 hours for a maximum of 3 doses.</p><p><strong>Results: </strong>The mean IAI (13.71±8.55 h and 13.22±8.22 h; <i>p</i>=0.768), mean number of misoprostol doses (2.08±1.08 and 2.54±1.12, <i>p</i>=0.05) and mean misoprostol dose (453.9±224.93 and 492.31±208.23 mcg, <i>p</i>=0.409) was similar. The complete abortion rate after 24 h (77.5% vs 87.5%, <i>p</i>=0.23), after 48 h (95% vs 97.5%, <i>p</i>=1.00) and minimal untoward effects seen were all similar in the two groups.</p><p><strong>Conclusions: </strong>Both SL and vaginal routes of misoprostol, after two doses of mifepristone were equally effective. The mean cumulative doses of misoprostol were similar, and a complete abortion rate of > 95% at 48 h was achieved with either route.<math><mo>></mo><mn>95</mn></math>.</p>","PeriodicalId":50491,"journal":{"name":"European Journal of Contraception and Reproductive Health Care","volume":" ","pages":"1-6"},"PeriodicalIF":1.9,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143411355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluating the fidelity of AI-generated information on long-acting reversible contraceptive methods. 评估人工智能生成的长效可逆避孕方法信息的保真度。
IF 1.9 4区 医学
European Journal of Contraception and Reproductive Health Care Pub Date : 2025-02-06 DOI: 10.1080/13625187.2025.2450011
Grace Riley, Elizabeth Wang, Camille Flynn, Ashley Lopez, Aparna Sridhar
{"title":"Evaluating the fidelity of AI-generated information on long-acting reversible contraceptive methods.","authors":"Grace Riley, Elizabeth Wang, Camille Flynn, Ashley Lopez, Aparna Sridhar","doi":"10.1080/13625187.2025.2450011","DOIUrl":"https://doi.org/10.1080/13625187.2025.2450011","url":null,"abstract":"<p><strong>Introduction: </strong>Artificial intelligence (AI) has many applications in health care. Popular AI chatbots, such as ChatGPT, have the potential to make complex health topics more accessible to the general public. The study aims to assess the accuracy of current long-acting reversible contraception information provided by ChatGPT.</p><p><strong>Methods: </strong>We presented a set of 8 frequently-asked questions about long-acting reversible contraception (LARC) to ChatGPT, repeated over three distinct days. Each question was repeated with the LARC name changed (e.g., 'hormonal implant' vs 'Nexplanon') to account for variable terminology. Two coders independently assessed the AI-generated answers for accuracy, language inclusivity, and readability. Scores from the three duplicated sets were averaged.</p><p><strong>Results: </strong>A total of 264 responses were generated. 69.3% of responses were accurate. 16.3% of responses contained inaccurate information. The most common inaccuracy was outdated information regarding the duration of use of LARCs. 14.4% of responses included misleading statements based on conflicting evidence, such as claiming intrauterine devices increase one's risk for pelvic inflammatory disease. 45.1% of responses used gender-exclusive language and referred only to women. The average Flesch readability ease score was 42.8 (SD 7.1), correlating to a college reading level.</p><p><strong>Conclusion: </strong>ChatGPT offers important information about LARCs, though a minority of responses are found to be inaccurate or misleading. A significant limitation is AI's reliance on data from before October 2021. While AI tools can be a valuable resource for simple medical queries, users should be cautious of the potential for inaccurate information.</p><p><strong>Short condensation: </strong>ChatGPT generally provides accurate and adequate information about long-acting contraception. However, it occasionally makes false or misleading claims.</p>","PeriodicalId":50491,"journal":{"name":"European Journal of Contraception and Reproductive Health Care","volume":" ","pages":"1-4"},"PeriodicalIF":1.9,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143257247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Safety and accuracy of dating unwanted pregnancies and detecting ectopic pregnancy with the RCOG decision aid without routine ultrasound - a retrospective analysis form a large abortion service. 无常规超声的RCOG决策辅助诊断意外妊娠和异位妊娠的安全性和准确性——一项大型流产服务的回顾性分析。
IF 1.9 4区 医学
European Journal of Contraception and Reproductive Health Care Pub Date : 2025-02-06 DOI: 10.1080/13625187.2025.2452175
Janina Kaislasuo, Oskari Heikinheimo
{"title":"Safety and accuracy of dating unwanted pregnancies and detecting ectopic pregnancy with the RCOG decision aid without routine ultrasound - a retrospective analysis form a large abortion service.","authors":"Janina Kaislasuo, Oskari Heikinheimo","doi":"10.1080/13625187.2025.2452175","DOIUrl":"https://doi.org/10.1080/13625187.2025.2452175","url":null,"abstract":"<p><strong>Background: </strong>Evidence suggests routine pre-abortion ultrasound is unnecessary for women with regular menstrual cycles and without symptoms or risk factors for ectopic pregnancy in early gestation.</p><p><strong>Objectives: </strong>We evaluated the safety and accuracy of using the decision aid for early medical abortion without ultrasound developed by the RCOG Abortion Care group in a Finnish setting.</p><p><strong>Method: </strong>Using gestational age (GA) expected by last menstrual period (LMP), cycle irregularities, use of hormonal contraceptives, breastfeeding and self-reported symptoms indicative of possible ectopic pregnancy, women were classified into 'no ultrasound needed' and 'ultrasound needed' with a cut-off of 10 + 0 weeks or 70 days. Findings on US were then evaluated to assess classification accuracy.</p><p><strong>Results: </strong>Between September and December 2023, 494 women attending the abortion clinic at the Helsinki University Hospital were assessed. Correct classification of the necessity of an ultrasound was made in 491/494 (99.4%) cases before the women had a scan. The remaining three cases were one woman with an unexpected GA just above 10 + 0, one asymptomatic ectopic pregnancy and one asymptomatic pregnancy of unknown location with high plasma hCG, diagnosed as a partial molar pregnancy on pathology after diagnostic vacuum aspiration.</p><p><strong>Conclusions: </strong>Use of the structured flowchart developed by the RCOG highly accurately identifies women needing an ultrasound examination. The few cases that would have been undetected highlight the importance of informing women and health care providers about symptoms of ectopic or abnormal pregnancy similar to practices in wanted pregnancies not routinely examined and dated before late first trimester.</p>","PeriodicalId":50491,"journal":{"name":"European Journal of Contraception and Reproductive Health Care","volume":" ","pages":"1-4"},"PeriodicalIF":1.9,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143257163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Simultaneous removal of impalpable implants in both the left and the right arm - a case report and implications for their use in low-resource settings. 同时移除左臂和右臂的植入物--病例报告及其在资源匮乏地区使用的意义。
IF 1.9 4区 医学
European Journal of Contraception and Reproductive Health Care Pub Date : 2025-02-01 Epub Date: 2024-10-16 DOI: 10.1080/13625187.2024.2413615
Norman D Goldstuck, Pumza Mjuleka
{"title":"Simultaneous removal of impalpable implants in both the left and the right arm - a case report and implications for their use in low-resource settings.","authors":"Norman D Goldstuck, Pumza Mjuleka","doi":"10.1080/13625187.2024.2413615","DOIUrl":"10.1080/13625187.2024.2413615","url":null,"abstract":"<p><p>Implanon NXT<sup>®</sup> is a single rod contraceptive implant that is a long-acting reversible contraceptive method. Placement and removal is usually simple if the instructions of use are followed. Deviation from these instructions may lead to the implant becoming impalpable and consequently difficult to remove. We report on a case of a 46- year- old woman who had an impalpable implant in both the left and the right upper arms simultaneously. They had been placed approximately ten and seven years previously and were probably not releasing etonogestrel and were no longer relied on for contraceptive efficacy. The implants were removed relatively easily after ultrasound mapping. This case highlights some of the problems with the provision of implants in low-resource settings. The problems of implant management and some practical suggestions regarding its use in these settings is discussed.</p>","PeriodicalId":50491,"journal":{"name":"European Journal of Contraception and Reproductive Health Care","volume":" ","pages":"39-41"},"PeriodicalIF":1.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142479715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The SARS-CoV-2 (COVID-19) pandemic and diagnosis and treatment of women with abnormal uterine bleeding: findings from Brazil. SARS-CoV-2 (COVID-19)大流行与子宫异常出血妇女的诊断和治疗:来自巴西的调查结果。
IF 1.9 4区 医学
European Journal of Contraception and Reproductive Health Care Pub Date : 2025-02-01 Epub Date: 2024-12-11 DOI: 10.1080/13625187.2024.2430285
Ilza Monteiro, Luis Bahamondes, Agnaldo Lopes Silva-Filho, Malcolm G Munro
{"title":"The SARS-CoV-2 (COVID-19) pandemic and diagnosis and treatment of women with abnormal uterine bleeding: findings from Brazil.","authors":"Ilza Monteiro, Luis Bahamondes, Agnaldo Lopes Silva-Filho, Malcolm G Munro","doi":"10.1080/13625187.2024.2430285","DOIUrl":"10.1080/13625187.2024.2430285","url":null,"abstract":"<p><strong>Objective: </strong>To determine practice patterns in the diagnosis and management of nongestational abnormal uterine bleeding (AUB) in women in reproductive years during the SARS-CoV-2 (COVID-19) pandemic in Brazil.</p><p><strong>Materials and methods: </strong>A web-based survey was conducted to determine the impact of the COVID-19 pandemic on the diagnosis and management of women with AUB. Survey elements included treatment location, the use of ultrasonography, laboratory evaluation for iron deficiency and some hormone determinations, and endometrial evaluation by histopathology, as well as the practice of hysteroscopy, hysterectomy and medical therapy including the placement of the 52 mg levonorgestrel-intrauterine system (LNG-IUS<sub>52</sub>). The survey was completed electronically at scientific meetings or sent by e-mail to Brazil-based OBGYNs between April and September 2021 during the COVID-19 quarantine.</p><p><strong>Results: </strong>Fully completed questionnaires were received from 541 physicians aged (mean ± SD) 46.6 ± 12.5 years. Whereas the overall number of AUB-related visits decreased (<i>p</i> < 0.001) compared to the pre-pandemic period, the reduction was in office-based encounters; AUB-related visits at emergency facilities did not change. Telehealth-based AUB consultations increased from 1.3% at pre-pandemic to 34.3% (<i>p</i> < 0.001) during the pandemic. There were significant reductions in the use of diagnostic hysteroscopy (<i>p</i> < 0.001), endometrial biopsy (<i>p</i> < 0.001), therapies with the LNG-IUS<sub>52</sub>, combined oral contraceptives and hysterectomies (<i>p</i> = 0.002, <i>p</i> = 0.006 and <i>p</i> < 0.001, respectively).</p><p><strong>Conclusions: </strong>In Brazil, during the COVID-19 pandemic, there was a decrease in AUB-related consultations, a slight increase in telehealth visits and a reduction in the use of procedures and treatments.</p>","PeriodicalId":50491,"journal":{"name":"European Journal of Contraception and Reproductive Health Care","volume":" ","pages":"49-53"},"PeriodicalIF":1.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142808477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Feasibility and acceptability of outpatient medical induction at 13-18 weeks' gestation in public sector hospitals in Nepal: a prospective cohort study. 尼泊尔公立医院妊娠 13-18 周门诊引产的可行性和可接受性:一项前瞻性队列研究。
IF 1.9 4区 医学
European Journal of Contraception and Reproductive Health Care Pub Date : 2025-02-01 Epub Date: 2024-10-30 DOI: 10.1080/13625187.2024.2416054
Anand Tamang, Ilana G Dzuba, Heera Tuladhar, Bhakta Batsal Raut, Sajan Kc, Achala Shrestha, Hillary Bracken, Ingrida Platais, Beverly Winikoff
{"title":"Feasibility and acceptability of outpatient medical induction at 13-18 weeks' gestation in public sector hospitals in Nepal: a prospective cohort study.","authors":"Anand Tamang, Ilana G Dzuba, Heera Tuladhar, Bhakta Batsal Raut, Sajan Kc, Achala Shrestha, Hillary Bracken, Ingrida Platais, Beverly Winikoff","doi":"10.1080/13625187.2024.2416054","DOIUrl":"10.1080/13625187.2024.2416054","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the feasibility and acceptability of outpatient medical induction at 13-18 weeks' gestation to limit overnight hospital stays.</p><p><strong>Methods: </strong>In this prospective cohort study, participants with 13-18-week pregnancies seeking abortions at two government hospitals swallowed mifepristone 200 mg and self-administered misoprostol 400 mcg buccally 24-48 h later, 1-2 h before returning to the outpatient clinic (OPD). Repeat misoprostol was dosed every 3 h until expulsion. Participants requiring care beyond OPD hours were admitted as inpatients. Acceptability was evaluated by exit interview before discharge. Participants were contacted two weeks later to assess any subsequent issues.</p><p><strong>Results: </strong>Ninety-eight (82%) of 120 participants had successful outpatient abortions using a median two (IQR 2, 3) misoprostol doses. The median induction-to-abortion time was five hours (IQR 4, 7.5). Eleven (9%) participants expelled before clinic arrival. Twenty-two (18%) participants were transferred as inpatients at OPD closing. Transferred participants remained inpatient for a median 18 h (IQR 18, 21.25). There were no serious adverse events and satisfaction with the abortion process was high.</p><p><strong>Conclusions: </strong>Although the outpatient model did not meet statistical expectations, it is clinically feasible, acceptable, and improves efficiency, expands access, and reduces burdens for women and providers. Operational adjustments may facilitate higher outpatient success.</p>","PeriodicalId":50491,"journal":{"name":"European Journal of Contraception and Reproductive Health Care","volume":" ","pages":"42-48"},"PeriodicalIF":1.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142548730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reproductive performance and obstetric outcomes after hysteroscopic septum resection. 宫腔镜下中隔切除术后的生殖性能和产科结局。
IF 1.9 4区 医学
European Journal of Contraception and Reproductive Health Care Pub Date : 2025-02-01 Epub Date: 2024-12-13 DOI: 10.1080/13625187.2024.2429381
Elif Aylin Taşkın, Kübra Dilbaz, Didem Demir, Berna Dilbaz, Yaprak Engin Üstün
{"title":"Reproductive performance and obstetric outcomes after hysteroscopic septum resection.","authors":"Elif Aylin Taşkın, Kübra Dilbaz, Didem Demir, Berna Dilbaz, Yaprak Engin Üstün","doi":"10.1080/13625187.2024.2429381","DOIUrl":"10.1080/13625187.2024.2429381","url":null,"abstract":"<p><strong>Purpose: </strong>The aim of this retrospective cohort study was to investigate the effects of hysteroscopic uterine septum resection on the clinical pregnancy rate (CPR), live birth rate (LBR) and miscarriage rate.</p><p><strong>Materials and method(s): </strong>Hospital records of consecutive patients who underwent hysteroscopic uterine septum resection between February 2021 and December 2022 were reviewed. They were telephoned and interviewed about their reproductive performance after surgery, and pregnancy outcomes, if achieved.</p><p><strong>Results and conclusions: </strong>Sixty-nine eligible patients were enrolled. Forty-one (59.4%) of these patients were referred to our clinic for otherwise unexplained infertility of at least 1 year and 28 (40.6%) for pregnancy loss. During the follow-up period, 32 patients conceived. The overall CPR was 46.4%, the LBR per woman was 36.2%, the LBR per pregnancy was 78.1% and the miscarriage rate was 12.5%. The LBRs per pregnancy were 83.3% and 71.4% in the infertility and miscarriage subgroups, respectively. The miscarriage rates per pregnancy were 0% and 28.6% in the infertility and miscarriage subgroups, respectively. Three of 6 patients whose uterine septum was incomplete but prominent became pregnant (CPR: 50.0%), and all pregnancies resulted in live birth (LBR per pregnancy:100%, LBR per woman:50%). Two patients with complete uterine septum didn't achieve pregnancy. Hysteroscopic uterine septum resection may improve the CPR, LBR and miscarriage rates in subfertile population with and without previous pregnancy loss.</p>","PeriodicalId":50491,"journal":{"name":"European Journal of Contraception and Reproductive Health Care","volume":" ","pages":"54-57"},"PeriodicalIF":1.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142819768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A randomised double-blind trial to determine the bleeding profile of the prolonged-release contraceptive dienogest 2 mg/ethinylestradiol 0.02 mg versus an immediate-release formulation of drospirenone 3 mg/ethinylestradiol 0.02 mg. 一项随机双盲试验,旨在确定 2 毫克/炔雌醇 0.02 毫克的长效缓释避孕药地诺孕酮与 3 毫克/炔雌醇 0.02 毫克的屈螺酮速释制剂的出血情况。
IF 1.9 4区 医学
European Journal of Contraception and Reproductive Health Care Pub Date : 2025-02-01 Epub Date: 2024-09-16 DOI: 10.1080/13625187.2024.2398433
Kristina Biskupska-Bodova, Joanna Sójka-Kupny, Tamás Nyirády, Anne E Burke, Alicyoy Angulo, Pedro Antonio Regidor
{"title":"A randomised double-blind trial to determine the bleeding profile of the prolonged-release contraceptive dienogest 2 mg/ethinylestradiol 0.02 mg versus an immediate-release formulation of drospirenone 3 mg/ethinylestradiol 0.02 mg.","authors":"Kristina Biskupska-Bodova, Joanna Sójka-Kupny, Tamás Nyirády, Anne E Burke, Alicyoy Angulo, Pedro Antonio Regidor","doi":"10.1080/13625187.2024.2398433","DOIUrl":"10.1080/13625187.2024.2398433","url":null,"abstract":"<p><strong>Background: </strong>Dienogest (DNG) 2 mg/ethinylestradiol (EE) 0.02 mg is the first low-dose combined oral contraceptive (COC) with a prolonged-release formulation that allows stable plasma concentrations and has high contraceptive efficacy (Pearl index: 0.2). The aim of this trial was to determine the bleeding profile of this contraceptive compared to an immediate release formulation.</p><p><strong>Methods: </strong>This prospective double-blind randomised controlled trial evaluated the bleeding patterns of DNG 2 mg/EE 0.02 mg compared with immediate-release drospirenone (DRSP) 3 mg/EE 0.02 mg in a 24/4-day regimen over nine cycles (randomisation ratio, 5:2). Participants recorded scheduled and unscheduled bleeding/spotting data using an electronic diary. A non-inferiority analysis for the proportion of participants with unscheduled bleeding/spotting was prespecified for Cycles 2-6. Safety, including adverse events, were monitored throughout the trial.</p><p><strong>Results: </strong>Seven-hundred six and 288 participants received DNG/EE and DRSP/EE, respectively. Scheduled bleeding patterns per each 28-day cycle were similar in both groups. During Cycles 2-6, the proportion of participants with unscheduled bleeding/spotting was significantly lower in the DNG/EE group (50.5% [280/574] than in the DRSP/EE group (72.8% [171/235]]; treatment difference 22.3% [95% CI 15.9, 28.6%]; <i>p</i> < 0.0001). A low proportion of participants discontinued the trial due to bleeding disorders (1.7% and 0.7%, respectively). The safety profiles were similar for both treatments.</p><p><strong>Conclusions: </strong>The prolonged-release DNG 2 mg/EE 0.02 mg offers a significant decrease in unscheduled bleeding/spotting compared with an immediate-release COC, DRSP/EE, combined with high contraceptive efficacy and a very low adverse event profile.</p>","PeriodicalId":50491,"journal":{"name":"European Journal of Contraception and Reproductive Health Care","volume":" ","pages":"3-12"},"PeriodicalIF":1.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142300023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Discontinuation of long-acting reversible contraception: a retrospective Dutch study in general practice. 长效可逆避孕药的停用:荷兰全科医生的一项回顾性研究。
IF 1.9 4区 医学
European Journal of Contraception and Reproductive Health Care Pub Date : 2025-02-01 Epub Date: 2024-10-18 DOI: 10.1080/13625187.2024.2415361
Theodora A M Teunissen, Antoinette L M Lagro-Janssen, Demi Sturkenboom, Reinier P Akkermans, Annemarie A Uijen
{"title":"Discontinuation of long-acting reversible contraception: a retrospective Dutch study in general practice.","authors":"Theodora A M Teunissen, Antoinette L M Lagro-Janssen, Demi Sturkenboom, Reinier P Akkermans, Annemarie A Uijen","doi":"10.1080/13625187.2024.2415361","DOIUrl":"10.1080/13625187.2024.2415361","url":null,"abstract":"<p><strong>Background: </strong>In the Netherlands, the use of long-acting reversible contraception (LARC) methods increases. Studies show high premature discontinuation rates of LARCs, but comprehensive insights into the Dutch situation remain limited.</p><p><strong>Aim: </strong>The aim of this study is to determine (1) the rate and reasons of discontinuation of different types of LARC in the first 2.5 years of use and (2) what patient characteristics are associated with premature discontinuation.</p><p><strong>Design and setting: </strong>Retrospective cohort study utilising data from a Dutch primary care research network.</p><p><strong>Methods: </strong>We included all women who received a LARC between 2017 and 2019 with a 2.5-year follow-up period. We performed a descriptive analysis, Kaplan Meier and logistic regression analysis to answer the research questions.</p><p><strong>Results: </strong>We included 642 women. In total, 166 women (25.9%) discontinued their LARC within 2.5 years. Discontinuation rates were 22% for levonorgestrel intra-uterine systems (LNG-IUS) 52 mg, 25% for LNG-IUS 19.5 mg, 39% for copper IUDs and 47% for subdermal implants. Common reasons for discontinuation were: alterations in bleeding pattern (68%), abdominal pain (32%), headache or mood fluctuation (24%) and a preference for natural contraceptive methods (23%). Factors associated with discontinuation for reasons other than pregnancy wish were: age between 30 and 34 years old (OR 5.1, 95% CI [1.26-20.48]) and a history of sexual, physical and/or psychological abuse (OR 3.16, 95% CI [1.60-6.23]). A high educational level (OR 0.33, 95% CI [0.12-0.89]) was associated with a lower risk of discontinuation.</p><p><strong>Conclusion: </strong>The discontinuation rates of LARCs are high. Better counselling might prevent premature discontinuation.</p>","PeriodicalId":50491,"journal":{"name":"European Journal of Contraception and Reproductive Health Care","volume":" ","pages":"33-38"},"PeriodicalIF":1.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142479713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Knowledge of contraceptive methods among deaf women: a qualitative study. 聋哑妇女对避孕方法的了解:一项定性研究。
IF 1.9 4区 医学
European Journal of Contraception and Reproductive Health Care Pub Date : 2025-02-01 Epub Date: 2024-12-13 DOI: 10.1080/13625187.2024.2429373
Gabriela Fuster Barbosa, Laura Fernandes Berto, Sandra Dircinha Teixeira de Araujo Moraes, Edson Santos Ferreira-Filho, Luis Bahamondes, Edmund Chada Baracat, José Maria Soares-Junior, Isabel Cristina Esposito Sorpreso
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