European Journal of Contraception and Reproductive Health Care最新文献

{"title":"Authors response to article retraction.","authors":"Ahmed Mohamed Maged","doi":"10.1080/13625187.2023.2183079","DOIUrl":"https://doi.org/10.1080/13625187.2023.2183079","url":null,"abstract":"Regarding the retraction decision of the article entitled ‘Benefits of vaginal misoprostol prior to IUD insertion in women with previous caesarean delivery: a randomised controlled trial, The European Journal of Contraception & Reproductive Health Care, 23:1, 32–37, DOI: 10.1080/ 13625187.2018.1428297.’ The authors need to clarify some data to the authors The investigating team had asked for the raw data, ethical committee approval, informed consent and the protocol submitted. These files were checked and no concerns were raised about them. The editor decided to retract the paper based on the following issues.","PeriodicalId":50491,"journal":{"name":"European Journal of Contraception and Reproductive Health Care","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9691730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Women's decision-making related to induced abortion - a cross sectional study during a period of Covid-19 pandemic, in Sweden.","authors":"M Makenzius,&nbsp;C Obern,&nbsp;T Tydén,&nbsp;M Larsson,&nbsp;K Gemzell-Danielsson,&nbsp;I Sundström-Poromaa,&nbsp;M Ekstrand Ragnar","doi":"10.1080/13625187.2022.2150047","DOIUrl":"https://doi.org/10.1080/13625187.2022.2150047","url":null,"abstract":"<p><strong>Objectives: </strong>To investigate women's decision-making on induced abortion.</p><p><strong>Materials and methods: </strong>A multi-centre cross-sectional survey among 623 abortion-seeking women in Sweden (2021). The perceived difficulty to decide on abortion was measured using a 7-point Likert scale, and analysed with univariate and multivariate analysis (odds ratios [OR], 95% confidence intervals [CI]).</p><p><strong>Results: </strong>About half (<i>n</i> = 322;52%) scored 1-4, suggesting the decision was perceived as easier compared to those (<i>n</i> = 292;48%) who scored 5-7. Reasons for the abortion were: poor economy (<i>n</i> = 166;27%), too early in the relationship (<i>n</i> = 154;25.1%), want to work first (<i>n</i> = 147;23.9%), want to study first (<i>n</i> = 132;21.5%), uncertain about the relationship (104;16.9%), and too young (<i>n</i> = 104;16.9%). Predictors for perceiving the decision as difficult: partner's hesitance (OR = 3.18, CI:1.76-5.73), being born outside the Nordic countries (OR = 2.23, CI:1.28-3.87), having discussed the decision with someone (OR = 2.42, CI:1.67-3.50), age ≥30 (OR = 2.22, CI:1.03-4.76), the Covid-19 pandemic (OR = 2.08, CI:1.20-3.59), and the desire to have children in the future (OR = 1.96, CI:1.18-3.28). After confirmed pregnancy, poor mental well-being was more common among those who scored 5-7 (<i>n</i> = 140;47.9%) compared to those who scored 1-4 (<i>n</i> = 122;37.9), <i>p</i> = .029.</p><p><strong>Conclusion: </strong>Women's decision-making on abortion is complex; in times of crises, the decision procedure may be even more difficult. This valuable knowledge could be used to improve and promote satisfactory counselling beyond medical routines.</p>","PeriodicalId":50491,"journal":{"name":"European Journal of Contraception and Reproductive Health Care","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10640403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"One-year follow-up of immediate postpartum contraceptive implant insertion in adolescents.","authors":"Mariane M Barbieri,&nbsp;Amanda Dantas-Silva,&nbsp;Leticia S Caleffi,&nbsp;Sirlei S Morais,&nbsp;Cassia R T Juliato,&nbsp;Luis Bahamondes,&nbsp;Fernanda G Surita","doi":"10.1080/13625187.2022.2133536","DOIUrl":"https://doi.org/10.1080/13625187.2022.2133536","url":null,"abstract":"<p><strong>Purpose: </strong>Our study aimed to evaluate the acceptability, adverse effects and continuation rates among adolescents who accepted the etonogestrel (ENG) subdermal implant and compared to adolescents who chose other methods during the immediate postpartum period before hospital discharge, with one year follow-up up.</p><p><strong>Materials and methods: </strong>We conducted a cohort non-randomised study at the Women's Hospital, University of Campinas. All women up to 19 years of age, who gave birth at the hospital between July 2019 and April 2020, were invited to participate and were offered the ENG-implant or the routine contraceptive methods. They were followed for one year postpartum.</p><p><strong>Results: </strong>We included 100 teenagers and 72 accepted the ENG-implant. Students are more likely to accept the ENG-implant than non-students (PR: 1.25 [95%CI 0.99-1.59]). Up to one year of follow-up, survival analysis showed that the time of adherence to the method was longer for the ENG-implant users (<i>p</i> = 0.0049). More than 90% of the adolescents were satisfied with the implant; however, five requested early removal due to menstrual irregularity and local discomfort.</p><p><strong>Conclusion: </strong>Provision ENG-implant for adolescents in the immediate postpartum demonstrated high acceptance and ensured effective contraception. After one year, most of them were satisfied, with a high continuation rate and without unplanned pregnancies.</p>","PeriodicalId":50491,"journal":{"name":"European Journal of Contraception and Reproductive Health Care","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10644657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"\"Better late than never but never late is better\", especially in young women. A multicenter Italian study on diagnostic delay for symptomatic endometriosis.","authors":"Ida Pino,&nbsp;Gaia Maria Belloni,&nbsp;Valeria Barbera,&nbsp;Eugenio Solima,&nbsp;Davide Radice,&nbsp;Stefano Angioni,&nbsp;Saverio Arena,&nbsp;Valentino Bergamini,&nbsp;Massimo Candiani,&nbsp;Antonio Maiorana,&nbsp;Alberto Mattei,&nbsp;Ludovico Muzii,&nbsp;Luca Pagliardini,&nbsp;Maria Grazia Porpora,&nbsp;Valentino Remorgida,&nbsp;Renato Seracchioli,&nbsp;Paolo Vercellini,&nbsp;Fulvio Zullo,&nbsp;Errico Zupi,&nbsp;Michele Vignali","doi":"10.1080/13625187.2022.2128644","DOIUrl":"https://doi.org/10.1080/13625187.2022.2128644","url":null,"abstract":"<p><strong>Purpose: </strong>The aim of the study was to assess the length of diagnostic delay of symptomatic endometriosis in Italy and analyse the presence of correlations between the socio-demographic status of patients and the clinical characteristics/type of diagnosis.</p><p><strong>Materials and methods: </strong>This multicenter cross-sectional questionnaire-based study was conducted in 10 tertiary Italian referral centres for diagnosis and treatment endometriosis. A total of 689 respondents with histologically proven endometriosis and onset of the disease with pain symptoms completed an on-line self-reported questionnaire written in their own language (World Endometriosis Research Foundation-Endometriosis Phenome and Biobanking Harmonisation Project-Endometriosis Patient Questionnaire-Minimum) evaluating endometriosis related symptoms, family history of endometriosis and chronic pelvic pain, demographic data, as well as medical, reproductive, and obstetric history.</p><p><strong>Results: </strong>The mean diagnostic delay found was of 11.4 years. The mean time (14.8 years) from symptoms onset to diagnosis was significantly longer among patients aged 9-19 vs patients aged 20-30 (mean 6.9 years, <i>p</i> < 0.001) and patients aged 31-45 (mean 2.9, <i>p</i> < 0.001). No significant association were found between a delayed diagnosis and any of the clinically relevant factors such as the number or severity of the reported symptoms, familiarity, hormonal therapy intake or methodology of diagnosis.</p><p><strong>Conclusions: </strong>The mean diagnostic delay of endometriosis in Italy is about 11 years. The delay can be up to 4 years longer in patients with pain symptoms onset under 20 years. Educating clinicians and patients on pathologic nature of endometriosis related pelvic pain is advisable to reduce waiting time to diagnosis, especially for young women.</p>","PeriodicalId":50491,"journal":{"name":"European Journal of Contraception and Reproductive Health Care","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10648608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Attitudes towards menstruation: what women want? An Italian National Survey.","authors":"Carlo Bastianelli,&nbsp;Giovanni Grandi,&nbsp;Manuela Farris,&nbsp;Gabriella Brandolino,&nbsp;Giulia Paoni Saccone,&nbsp;Ilenia La Barbiera,&nbsp;Giuseppe Benagiano","doi":"10.1080/13625187.2022.2130686","DOIUrl":"https://doi.org/10.1080/13625187.2022.2130686","url":null,"abstract":"<p><strong>Objective: </strong>Many women experience negative feelings during menstrual bleeding. Aim of the study was to evaluate the attitudes of Italian women towards menstrual bleeding, their desire to reduce its frequency and knowledge of the existence of methods capable of achieving such an objective.</p><p><strong>Methods: </strong>An internet-based anonymous questionnaire has been sent to women willing to fill it in through different social media (Instagram, WhatsApp, Facebook, Twitter). The survey evaluated, objective parameters such as number of pads, use of painkillers, duration of period and pain intensity. Judgement towards period and knowledge about methods to reduce frequency and amount of menstrual flow were analysed.</p><p><strong>Result: </strong>1072 Women aged 18 - 40 years, answered the survey. The level of education of responders was high, with 61.7% having a university degree. 27.5% of respondents viewed positively the occurrence of a menstrual period. Ideal frequency of menstrual cycles was considered 3 months and the perfect duration was considered to be 3 days. Half of the respondents ignored the existence of methods to suppress menstruation or reduce its frequency. 52% of participants stated that they would not use a contraceptive method because they considered it not 'natural'.</p><p><strong>Conclusions: </strong>In our sample, in spite of the discomfort reported by half of the women interviewed, menstruation was considered positively by one fourth as because confirm their fertility. The majority of women did consider bleeding every month a healthy, but they preferred a three-monthly frequency. Knowledge of contraceptive methods capable of reducing the frequency of menstrual bleeding was scarce.</p>","PeriodicalId":50491,"journal":{"name":"European Journal of Contraception and Reproductive Health Care","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10656221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Statement of Retraction: Benefits of vaginal misoprostol prior to IUD insertion in women with previous caesarean delivery: a randomised controlled trial.","authors":"","doi":"10.1080/13625187.2022.2156744","DOIUrl":"https://doi.org/10.1080/13625187.2022.2156744","url":null,"abstract":"","PeriodicalId":50491,"journal":{"name":"European Journal of Contraception and Reproductive Health Care","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10605038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Girls at risk: FGM intentions among in-school adolescents of a rural community in Osun State, Nigeria.","authors":"Olusola Fajobi,&nbsp;Oyelola Adeoye,&nbsp;Damola Fajobi,&nbsp;Temitope Olumuyiwa Ojo,&nbsp;Olusegun Temitope Afolabi","doi":"10.1080/13625187.2022.2135371","DOIUrl":"https://doi.org/10.1080/13625187.2022.2135371","url":null,"abstract":"<p><strong>Purpose: </strong>Knowledge of adolescents' intention to sustain female genital mutilation (FGM) practice is required to guide efforts to eradicate FGM in Africa and Asia where about 200 million women are affected. Nigeria has one of the highest FGM cases in the world. The study sought to determine the knowledge, attitude, and intentions of adolescents to sustain FGM practice when they become parents.</p><p><strong>Materials and methods: </strong>This study is a cross-sectional descriptive survey of 195 in-school adolescents aged 14-19 years, in Imesi-Ile, a rural town in South-west Nigeria selected through a multistage sampling method.</p><p><strong>Results: </strong>Overall, 44.6% of adolescents had good knowledge of FGM, while 44.6% had a positive attitude and 55.4% had a negative attitude towards FGM. More females (57.4%) have a negative attitude towards FGM. About 42.1% of adolescents intend to continue the practice of FGM, while 47% have no intentions and 10.8% remain undecided. Gender, age group and family affluence were not statistically associated with intention to continue FGM.</p><p><strong>Conclusion: </strong>Intention to continue FGM practice is high among adolescents in the rural community. FGM eradication campaign among adolescents should seek to improve knowledge, attitude and intentions towards FGM practice.</p>","PeriodicalId":50491,"journal":{"name":"European Journal of Contraception and Reproductive Health Care","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10630181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Contraceptive exposure associates with urinary tract infection risk in a cohort of reproductive-age women: a case control study.","authors":"Claire Lo,&nbsp;Abin Abraham,&nbsp;Cosmin A Bejan,&nbsp;Seth A Reasoner,&nbsp;Mario Davidson,&nbsp;Loren Lipworth,&nbsp;David M Aronoff","doi":"10.1080/13625187.2022.2156278","DOIUrl":"https://doi.org/10.1080/13625187.2022.2156278","url":null,"abstract":"<p><strong>Purpose: </strong>Although non-barrier contraception is commonly prescribed, the risk of urinary tract infections (UTI) with contraceptive exposure is unclear.</p><p><strong>Materials and methods: </strong>Using data from Vanderbilt University Medical Centre's deidentified electronic health record (EHR), women ages 18-52 were randomly sampled and matched based on age and length of EHR. This case-control analysis tested for association between contraception exposure and outcome using UTI-positive (UTI+) as cases and upper respiratory infection+ (URI+) as controls.</p><p><strong>Results: </strong>24,563 UTI + cases (mean EHR: 64.2 months; mean age: 31.2 years) and 48,649 UTI-/URI + controls (mean EHR: 63.2 months; mean age: 31.9 years) were analysed. In the primary analysis, UTI risk was statistically significantly increased for the oral contraceptive pill (OCP; OR = 1.10 [95%CI = 1.02-1.11], <i>p</i> ≤ 0.05), intrauterine device (IUD; OR = 1.13 [95%CI = 1.04-1.23], <i>p</i> ≤ 0.05), etonogestrel implant (Nexplanon^®; OR = 1.56 [95% CI = 1.24-1.96], <i>p</i> ≤ 0.05), and medroxyprogesterone acetate injectable (Depo-Provera^®; OR = 2.16 [95%CI = 1.99-2.33], <i>p</i> ≤ 0.05) use compared to women not prescribed contraception. A secondary analysis that included <i>any</i> non-IUD contraception, which could serve as a proxy for sexual activity, demonstrated a small attenuation for the association between UTI and IUD (OR = 1.09 [95%CI = 0.98-1.21], <i>p</i> = 0.13).</p><p><strong>Conclusion: </strong>This study notes potential for a small increase in UTIs with contraceptive use. Prospective studies are required before this information is applied in clinical settings.</p><p><strong>Condensation: </strong>Although non-barrier contraception is commonly prescribed, the risk of urinary tract infections (UTI) with contraceptive exposure is poorly understood. This large-cohort, case-control study notes potential for a small increase in UTIs with contraceptive use.</p>","PeriodicalId":50491,"journal":{"name":"European Journal of Contraception and Reproductive Health Care","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9206934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bleeding profile satisfaction and pain and ease of placement with levonorgestrel 19.5 mg IUD: findings from the Kyleena^® Satisfaction study.","authors":"Gilbert Donders,&nbsp;Helena Kopp Kallner,&nbsp;Brian Hauck,&nbsp;Anja Bauerfeind,&nbsp;Ann-Kathrin Frenz,&nbsp;Michal Zvolanek,&nbsp;Dale W Stovall","doi":"10.1080/13625187.2022.2136939","DOIUrl":"https://doi.org/10.1080/13625187.2022.2136939","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate bleeding profile satisfaction and pain and ease of placement with levonorgestrel 19.5 mg IUD in routine clinical practice.</p><p><strong>Methods: </strong>Women who independently chose levonorgestrel 19.5 mg IUD during routine counselling were invited to participate in this prospective, multinational, observational study. Patient-reported pain and clinician-reported ease of placement were assessed. Bleeding profile satisfaction was evaluated at 12 months/premature end of observation.</p><p><strong>Results: </strong>Most participants (77.8%, <i>n</i> = 878/1129) rated levonorgestrel 19.5 mg IUD placement pain as 'none' or 'mild' and most clinicians (91.1%, <i>n</i> = 1029/1129) rated placement as 'easy'. Pain was more often rated higher in nulliparous compared with parous (<i>p</i> < .0001) and younger (<26 years) compared with older participants (<i>p</i> < .0001), although 67.7% and 69.0% of nulliparous and younger participants respectively reported 'none' or 'mild' pain. Bleeding profile satisfaction at 12 months/end of observation was similar in parous (72.9%, <i>n</i> = 318/436) and nulliparous (69.6%, <i>n</i> = 314/451) participants. Most participants irrespective of age reported bleeding profile satisfaction, ranging from 67.8% (<i>n</i> = 206/304) for 18-25 years to 76.5% (<i>n</i> = 218/285) for >35 years.</p><p><strong>Conclusion: </strong>We observed high bleeding profile satisfaction regardless of age or parity with levonorgestrel 19.5 mg IUD and confirmed that device placement is easy and associated with no more than mild pain in most cases in routine clinical practice. Real-world evidence from the Kyleena^® Satisfaction Study in routine clinical practice shows high bleeding profile satisfaction with levonorgestrel 19.5 mg IUD regardless of age or parity. IUD placement was easy and associated with little to no pain for most women.</p>","PeriodicalId":50491,"journal":{"name":"European Journal of Contraception and Reproductive Health Care","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10637019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The far-reaching impact of abortion bans: reproductive care and beyond.","authors":"Richard A Stein,&nbsp;Adi Katz,&nbsp;Frank A Chervenak","doi":"10.1080/13625187.2022.2140008","DOIUrl":"https://doi.org/10.1080/13625187.2022.2140008","url":null,"abstract":"<p><p>On 24 June 2022, the US Supreme Court overturned Roe v. Wade, a 49-year-old precedent that provided federal constitutional protection for abortions up to the point of foetal viability, returning jurisdiction to the individual states. Restrictions that came into effect automatically in several states, and are anticipated in others, will severely limit access to abortions in approximately half of the US. Even though every state allows for exceptions to the abortion bans, in some instances these exceptions can be used to preserve the health of a pregnant patient, while in other instances, only to preserve their life. The vague and confusing nature of the abortion ban exceptions threatens to compromise the standard of care for patients with pregnancy complications that are distinct from abortions, such as nonviable pregnancies, miscarriages, and ectopic pregnancies. Additionally, we envision challenges for the treatment of women with certain autoimmune conditions, pregnant cancer patients, and patients contemplating preimplantation genetic diagnosis as part of assisted reproductive technologies. The abortion ban exceptions will impact and interfere with the medical care of pregnant and non-pregnant patient populations alike and are poised to create a medical and public health crisis unlike any other one from the recent past.</p>","PeriodicalId":50491,"journal":{"name":"European Journal of Contraception and Reproductive Health Care","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10639104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}