Explore-The Journal of Science and Healing最新文献

{"title":"A journey within: Reflections on sleep apnea, evolution, and the mind-body axis in sleep medicine","authors":"Nimit Khara","doi":"10.1016/j.explore.2025.103255","DOIUrl":"10.1016/j.explore.2025.103255","url":null,"abstract":"<div><div>This reflective travelogue explores obstructive sleep apnea (OSA) as more than a physiological disorder, framing it within evolutionary, psychosomatic, and cultural dimensions. It examines how human bipedalism and sleep posture may predispose to OSA, while drawing parallels with animal observations and ancient traditions. Symbolic interpretations of sleeping positions highlight the interplay of mind, body, and consciousness. The essay critiques CPAP therapy as effective yet mechanistic, envisioning integrative approaches combining modern science with mindfulness, yoga, and chronobiological practices. Ultimately, it calls for a holistic vision of sleep medicine that harmonizes evidence-based interventions with timeless wisdom.</div></div>","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":"21 6","pages":"Article 103255"},"PeriodicalIF":2.2,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145049005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bridging cosmos and clinic: Ethnobotanical investigations of Indian astro-herbalism","authors":"Prasanna R. Deshpande","doi":"10.1016/j.explore.2025.103235","DOIUrl":"10.1016/j.explore.2025.103235","url":null,"abstract":"<div><div>This letter proposes a multidisciplinary research program to scientifically investigate Indian astro-herbalism, a culturally significant yet undocumented practice linking planetary influences to plant-based remedies. Despite skepticism, this approach has historically yielded effective drugs. The program will involve ethnographic mapping, phytochemical profiling, mechanistic studies, and preclinical/clinical evaluations of astrologically associated herbs like <em>Asparagus racemosus</em> and <em>Bacopa monnieri</em>. This inquiry aims to identify pharmacologically active compounds aligned with traditional indications, contributing to ethnopharmacology and biocultural drug discovery, and aligning with WHO's call for integrating traditional medicine into modern healthcare.</div></div>","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":"21 6","pages":"Article 103235"},"PeriodicalIF":2.2,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144861291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synergy of spiritual ambience, sattvic dietary regimen, homely care, and conventional medical therapy in the holistic rehabilitation of a terminally ill patient with post-traumatic complications: A case report","authors":"Anand Pratap Singh ,&nbsp;Rocktotpal Konwarh ,&nbsp;Kavita Tyagi ,&nbsp;Abhinav Singh ,&nbsp;Raghavendra Patil ,&nbsp;Mintu Moni Sarma ,&nbsp;Ramesh C. Deka ,&nbsp;Suvendra Kumar Ray","doi":"10.1016/j.explore.2025.103229","DOIUrl":"10.1016/j.explore.2025.103229","url":null,"abstract":"<div><h3>Objective</h3><div>To explore the integration of pharmacotherapy with a holistic approach incorporating a spiritual ambience, <em>sattvic</em> diet and homely care, in medical intervention of a complex multi-systemic post-trauma terminally ill patient.</div></div><div><h3>Case Presentation and Outcomes</h3><div>A 45-year-old female, declared terminally ill and presenting with progressively worsening symptoms twenty days post-road traffic accident, sought care at Baba Kinaram Hospital (BKH) on July 31, 2024. She exhibited severe hypoxia, severe respiratory distress, dilated cardiomyopathy (LVEF 35 %), dizziness, and neurological deficits, having received previously a dire prognosis from several multi-specialty hospital treatments. At BKH, despite minimal facilities, similar pharmacotherapeutic interventions were administered. These were uniquely augmented by an immersive spiritual ambience, a prescribed <em>sattvic</em> diet offered as <em>'prasad'</em> (consecrated food) and dedicated homely care within an <em>Ashram</em>-like setting guided by the principles of selfless service (Sanskrit: <em>Niskam Sewa) and ‘Knowledge is to serve</em>’ (Sanskrit: <em>Vigyanam Sewarthaya</em>). Following six days of inpatient treatment and a six-month follow-up, the patient showed remarkable clinical improvement. This included stabilization of oxygen levels, resolution of dizziness and headache, recovery of independent gait, and a significant increase in left ventricular ejection fraction to 68 %. This profound recovery, achieved with largely consistent medication but within a distinct holistic framework, underscores the critical role of the spiritual environment, specific dietary interventions, and supportive care alongside medical treatments for severe trauma patients. A questionnaire-based survey at discharge assessed the patient perceptions of hospital staff, medication, spiritual environment, homely care, and the diet's impact on her recovery. Patient perceptions of general health, costs, medication reliance, and six-month post-discharge sattvic diet adherence were also evaluated.</div></div><div><h3>Conclusion</h3><div>This report highlights the benefits of a patient-centred, holistic care model. Integrating psychological, social, and spiritual dimensions beyond physiological parameters, this approach significantly enhances overall health outcomes and advocates for holistic dietary and spiritual elements in managing complex post-traumatic symptoms.</div></div>","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":"21 5","pages":"Article 103229"},"PeriodicalIF":1.9,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144704598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to “Critical analysis of the article – A double-blind, randomized, placebo-controlled trial of individualized homeopathic medicinal products in the treatment of nocturnal enuresis in children”","authors":"Parth Aphale ,&nbsp;Himanshu Shekhar ,&nbsp;Shashank Dokania","doi":"10.1016/j.explore.2025.103227","DOIUrl":"10.1016/j.explore.2025.103227","url":null,"abstract":"","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":"21 5","pages":"Article 103227"},"PeriodicalIF":1.9,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144662269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"“The effect of acupressure on fatigue in individuals with chronic fatigue syndrome”","authors":"Doğukan Kurç ,&nbsp;Ayşe Arzu SAYIN ŞAKUL ,&nbsp;Esra ATILGAN","doi":"10.1016/j.explore.2025.103231","DOIUrl":"10.1016/j.explore.2025.103231","url":null,"abstract":"<div><h3>Background and Aim</h3><div>Patients with Chronic Fatigue Syndrome (CFS) often experience fatigue that greatly affects their quality of life. We aimed to investigate the effectiveness of acupressure in alleviating CFS symptoms in office workers.</div></div><div><h3>Methods</h3><div>We conducted a randomized controlled trial with 39 participants (28 women, 11 men; average age 29.54 ± 1.27). Participants were divided into treatment and control groups. The acupressure group received 10 sessions over 4 weeks, targeting specific acupoints (Li4, HT7, L9, P6, Gb20, Anmian, Du20, Yin-Tang, Sp6). Each point was stimulated for 30–90 s until numbness was felt; otherwise, stimulation lasted 90 s, totaling approximately 30 min per session. The control group did not receive any treatment. We assessed fatigue using the Fatigue Severity Scale (FSS), quality of life using the Short Form-36 (SF-36), and depressive symptoms using the Beck Depression Scale (BDS) before and after treatment. Data were analyzed using SPSS 22.0.</div></div><div><h3>Results</h3><div>We observed a significant reduction in fatigue severity in the acupressure group compared to the control group, where fatigue severity increased (<em>p</em> = 0.009). The acupressure group also demonstrated significant improvements in depressive symptoms (<em>p</em> = 0.000) and various quality of life sub-parameters: physical function (<em>p</em> = 0.02), physical role difficulty (<em>p</em> = 0.002), emotional role difficulty (<em>p</em> = 0.007), energy (<em>p</em> = 0.002), and mental health (<em>p</em> = 0.05).</div></div><div><h3>Conclusion</h3><div>Acupressure effectively alleviates CFS symptoms, highlighting its clinical potential as an accessible complementary therapy for office workers with CFS. These findings support integrating acupressure into routine clinical practice and encourage further investigation into its long-term benefits.</div></div>","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":"21 5","pages":"Article 103231"},"PeriodicalIF":2.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144739438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Environmental woes and the role of Indigenous knowledges","authors":"Natasha Tassell-Matamua","doi":"10.1016/j.explore.2025.103210","DOIUrl":"10.1016/j.explore.2025.103210","url":null,"abstract":"","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":"21 5","pages":"Article 103210"},"PeriodicalIF":1.9,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144605315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to “Constructive appraisal of “retrospective case control study of microcurrent therapy in autism spectrum disorder: Behavioral outcomes and dose-response analysis”","authors":"Himanshu Shekhar ,&nbsp;Dr. Parth Aphale ,&nbsp;Shashank Dokania","doi":"10.1016/j.explore.2025.103213","DOIUrl":"10.1016/j.explore.2025.103213","url":null,"abstract":"","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":"21 5","pages":"Article 103213"},"PeriodicalIF":1.9,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144605316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of self-auriculotherapy on the severity of restless leg syndrome, sleep quality, and fatigue in hemodialysis patients: A randomized controlled clinical trial","authors":"Fatemeh Asgari ,&nbsp;Mohammad Aghajani ,&nbsp;Sara Mortazavi Nia","doi":"10.1016/j.explore.2025.103205","DOIUrl":"10.1016/j.explore.2025.103205","url":null,"abstract":"<div><h3>Background</h3><div>Restless Legs Syndrome (RLS) is a sensory-motor sleep disorder common among hemodialysis patients. Today, complementary and alternative medicine considered in alleviating symptoms for some people with RLS. The aim of this study was to investigate the effect of self-auriculotherapy on the severity of Restless Leg Syndrome (RLS), sleep quality, and fatigue among hemodialysis patients.</div></div><div><h3>Methods</h3><div>This was randomized controlled trial. Sixty participants randomly assigned to either an intervention or a sham group. The intervention, consisting of auriculotherapy sessions conducted three times a week for six weeks, was assessed using validated scales at baseline, week six, and week ten.</div></div><div><h3>Results</h3><div>Significant improvements observed in RLS severity, sleep quality, and fatigue in the intervention group compared to the sham group at baseline, week 6, and week 10. The auriculotherapy group showed significant improvements in mean RLS, Pittsburgh Sleep Quality Index (PSQI) and Multidimensional Fatigue Inventory (MFI) scores compared to baseline at week 6 and week 10. (<em>P</em> &lt; 0.0001).</div></div><div><h3>Conclusions</h3><div>Our findings suggest that auriculotherapy is an effective non-pharmacological treatment for managing RLS and enhancing sleep quality and fatigue in hemodialysis patients. The study underscores the potential of auriculotherapy as a non-invasive, time-efficient therapeutic option, although further research with varied populations and longer follow-up periods recommended confirming these findings.</div></div>","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":"21 5","pages":"Article 103205"},"PeriodicalIF":1.9,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144548942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Masthead page","authors":"","doi":"10.1016/S1550-8307(25)00141-7","DOIUrl":"10.1016/S1550-8307(25)00141-7","url":null,"abstract":"","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":"21 5","pages":"Article 103250"},"PeriodicalIF":2.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145003863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A proposal to “Whole” our knowing: Clinical medicine in the Noosphere","authors":"Joseph J. Lamb ,&nbsp;P. Michael Stone ,&nbsp;Lindsey E. Wilkens ,&nbsp;Deanna M. Minich ,&nbsp;Jeffrey S. Bland ,&nbsp;Brian Thomas Swimme","doi":"10.1016/j.explore.2025.103203","DOIUrl":"10.1016/j.explore.2025.103203","url":null,"abstract":"<div><div>A significant challenge facing healthcare clinicians during communication with their patients relates to the context and frame of reference of the conversation between practitioner and patient. Individuals often have unique perspectives on the origin of their health and disease patterns. These perspectives are influenced by their “knowing” of themselves and the world they inhabit. This concept of “knowing” derives from a perspective encompassing physical, psychological, and cosmological domains. Contemporary medicine has traditionally focused heavily on the physical contributions to health and disease, whereas historically, cultures have drawn their “knowing” from their personal and spiritual relationship to planetary health and cosmological processes. A critical convergence of these perspectives is emerging in a broader and more inclusive way of “knowing” in the 21st century. One of the most potent models of knowing derives from the evolutionary sciences. We now know that each of us emerges out of a fourteen-billion-year evolutionary process. Each of us is suffused with the same energy that transformed clouds of atoms into radiant stars and ignited life on our planet. Modern science has demonstrated that our self-healing processes were constructed over 200 million years of mammalian evolution. From a cosmological perspective, healing can be understood as interventions that amplify the self-healing capacities of our bodies. This process of amplification is unique to each person. This is the N-of-1 era where respect for differences in “knowing” requires a broad-based understanding of the entire spectrum of relationships that an individual experiences with their environment and lifestyle.</div></div>","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":"21 5","pages":"Article 103203"},"PeriodicalIF":1.9,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144570927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}