{"title":"Effects of a traditional herbal formula containing Melissa officinalis, Pimpinella anisum, and Rosa damascena on anxiety and depression in patients with constipation-predominant irritable bowel syndrome (IBS-C): A double-blind randomized clinical trial","authors":"Maryam Azimi , Hossein Karimi Dokht Shahrbabaki , Mahboobeh Raeiszadeh , Omid Eslami","doi":"10.1016/j.explore.2024.05.011","DOIUrl":"10.1016/j.explore.2024.05.011","url":null,"abstract":"<div><h3>Introduction</h3><p>Irritable bowel syndrome (IBS) is associated with a high prevalence of anxiety and depression. This study aimed to evaluate the effects of a traditional Persian herbal formula containing <em>Melissa officinalis, Pimpinella anisum</em>, and <em>Rosa damascena</em> (MPR) on anxiety and depression in IBS patients with symptoms of constipation-predominant IBS (IBS-C).</p></div><div><h3>Methods</h3><p>This double-blind randomized clinical trial was conducted in Afzalipour Hospital via block randomization method. A total of 96 IBS-C patients (based on Rome IV criteria), aged 18–60 years, were included in this study. Participants received capsules containing either 500 mg of herbal formula or placebo (cornstarch) twice a day for four weeks Anxiety and depression were assessed using the Hospital Anxiety and Depression Scale.</p></div><div><h3>Results</h3><p>Forty-three patients in the intervention group and 45 patients in the control group completed this study. Except for the education level, there were no significant differences in the demographic characteristics between the two groups (<em>P</em> > 0.05). The mean levels of anxiety and depression, and total IBS symptom severity score showed no significant differences between the two groups at baseline (<em>P</em> > 0.05). After four weeks of treatment, the anxiety score considerably improvement in the treatment group (Cohen's <em>d</em> = -1.19, 95 % confidence intervals [CIs] -4.49 to 2.13), as did the depression score (Cohen's <em>d</em> = -1.93, 95 % CIs -4.32 to 2.79).</p></div><div><h3>Conclusion</h3><p>MPR considerably improved anxiety and depression in patients with IBS-C compared to the placebo without serious side effects.</p></div>","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":"20 6","pages":"Article 103013"},"PeriodicalIF":1.9,"publicationDate":"2024-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141472195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prevalence and determinants of massage therapy use in the U.S.: Findings from the 2022 National Health Interview Survey","authors":"Jeff Levin , Matt Bradshaw","doi":"10.1016/j.explore.2024.05.013","DOIUrl":"10.1016/j.explore.2024.05.013","url":null,"abstract":"<div><h3>Background</h3><p>This study presents findings on the prevalence and determinants of past-year massage therapy use among U.S. adults from the 2022 round of the National Health Interview Survey (NHIS) (total available N = 27,651), an annual national population survey.</p></div><div><h3>Methods</h3><p>The NHIS uses face-to-face interviews on a representative sample of the civilian, noninstitutionalized U.S. population drawn using a systematic, stratified, single-stage probability design. The analyses consist of logistically modeling the determinants of three outcome (dependent) measures: past year utilization of a practitioner of massage, past year utilization of massage for pain, and past-year utilization of massage to restore overall health. Exposure (independent) variables include numerous sociodemographic, health services, health-related, mental health and well-being, and behavioral indicators.</p></div><div><h3>Results</h3><p>The past-year prevalence rate for visiting a massage therapist in the U.S. is 11.1 %. The past-year rate for massage visits for pain is 6.0 %, and for restoring overall health is 8.5 %. Significantly higher rates are found among females and socioeconomically advantaged individuals, among other categories, and the strongest net determinant of massage therapy utilization is use of complementary or integrative practitioners.</p></div><div><h3>Conclusion</h3><p>It is apparent that massage therapy is a commonly utilized therapeutic modality in the U.S. While use of complementary or integrative therapies is a significant determinant of massage utilization, it may not be fitting to consider massage therapy itself as an “alternative” therapy, but rather a widely used and increasingly mainstream therapeutic modality meriting wider integration into the community of healthcare professions.</p></div>","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":"20 6","pages":"Article 103015"},"PeriodicalIF":1.9,"publicationDate":"2024-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141248908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Şerife İrem Döner , Hasan Gerçek , Özlem Akkoyun Sert , Ayça Aytar , Aydan Aytar
{"title":"The effects of aromatherapy massage in menopausal women with knee osteoarthritis: A randomized controlled study","authors":"Şerife İrem Döner , Hasan Gerçek , Özlem Akkoyun Sert , Ayça Aytar , Aydan Aytar","doi":"10.1016/j.explore.2024.05.012","DOIUrl":"10.1016/j.explore.2024.05.012","url":null,"abstract":"<div><h3>Objective</h3><p>Knee Osteoarthritis (OA)’s prevalence increases during menopause. Aromatherapy massage with different oils is applied in the treatment of knee OA. The aim of this study was to determine the effects of aromatherapy massage with Bergamot essential oil (BEO) on pain, functionality, sleep quality and menopausal symptoms in menopausal women with knee OA.</p></div><div><h3>Materials and methods</h3><p>This study included 60 menopausal participants diagnosed with grade II-III OA. Participants were randomly divided into three groups: BEO (n=20), placebo (n=20) and control (n=20). The participants in the BEO group, received aromatherapy massage with BEO, in the placebo group aromatherapy massage with sweet almond oil was applied twice a week for 4 weeks. All participants underwent conventional physiotherapy. Visual Analog Scale was used to assess the severity of pain, Osteoarthritis Index to assess functionality, Pittsburgh Sleep Quality Index to assess sleep quality and Menopausal Symptoms Rating Scale to assess menopausal symptoms. All measurements were performed before and after the study.</p></div><div><h3>Results</h3><p>The results of the study showed that all three groups were effective on pain, functionality, sleep quality and menopausal symptoms (p<0.001). The results of the study showed that, aromatherapy massage with BEO was found to be more effective on functionality (p<0.001), pain (p<0.001) and menopausal symptoms (somatic and psychological symptoms) (p<0.001) compared to the control and placebo groups. It was determined that aromatherapy massage with BEO did not create a significant difference between the sleep quality scale scores in the control group and the placebo group (p=0.454).</p></div><div><h3>Conclusion</h3><p>This study found that aromatherapy massage with BEO improved functionality, reduced pain and menopausal symptoms, and did not affect sleep quality. We consider that its application in addition to routine treatment may be useful to reduce symptoms.</p></div>","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":"20 6","pages":"Article 103014"},"PeriodicalIF":1.9,"publicationDate":"2024-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141137866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The effect of soy isoflavones given to women in the climacteric period on menopausal symptoms and quality of life: Systematic review and meta-analysis of randomized controlled trials","authors":"Nuran GENÇTÜRK , Fatma Şule BİLGİÇ , Hülya Ulaşlı KABAN","doi":"10.1016/j.explore.2024.05.010","DOIUrl":"10.1016/j.explore.2024.05.010","url":null,"abstract":"<div><h3>Objective</h3><p>This systematic review and meta-analysis aimed to examine the effect of soy isoflavones on menopausal symptoms and quality of life in climacteric women.</p></div><div><h3>Method</h3><p>The literature search was conducted in PubMed, CINAHL, Scopus, and Science Citation Index (Web of Science) until September 2023. This study is based on the recommendations of the Cochrane guidelines. The data were analysed using the Review Manager computer software (Version 5.4). The methodological quality of the studies was assessed with the RoB-2 tool.</p></div><div><h3>Results</h3><p>This analysis was completed with five studies and 425 climacteric women. According to the results of the analysis, menopausal symptoms (SMD: −0.49, 95 % CI: −1.13 to 0.16, <em>Z</em> = 1.47, <em>p</em> = 0.14), physical component (MD: −1.10, 95 % CI: −4.22 to 2.01, <em>Z</em> = 0.70, <em>p</em> = 0. 49) and mental component (MD: 0.81, 95 % CI: −6.73 to 8.35, <em>Z</em> = 0.21, <em>p</em> = 0.83), but there was a significant difference in depression level (SMD: −0.41, 95 % CI: −0.73 to −0.09, <em>Z</em> = 2.53, <em>p</em> = 0.01).</p></div><div><h3>Conclusion</h3><p>According to the results of the analysis, soy isoflavones had no effect on menopausal symptoms (vasomotor, psychosocial, physical, sexual, and urogenital complaints) and quality of life in climacteric women but did reduce the level of depression. There was a high risk of conflict of interest in the included studies.</p></div><div><h3>PROSPERO database</h3><p>Registration: CRD420234479700.</p></div>","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":"20 6","pages":"Article 103012"},"PeriodicalIF":1.9,"publicationDate":"2024-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141132003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Julia M. Hush , Daniel Steffens , Michael J. Solomon
{"title":"A patient-designed integrative oncology intervention for stage IV locally recurrent rectal cancer: A case report","authors":"Julia M. Hush , Daniel Steffens , Michael J. Solomon","doi":"10.1016/j.explore.2024.05.002","DOIUrl":"10.1016/j.explore.2024.05.002","url":null,"abstract":"<div><h3>Introduction</h3><p>Stage IV colorectal cancer is a highly challenging condition to treat, with 5-year survival rates of 13% in Australia, improving to 40% for those patients with locally recurrent rectal cancer who are suitable for total neoadjuvant therapy and pelvic exenterative surgery. This study reports a unique case of a patient with Stage IV locally recurrent rectal cancer (LRRC), who designed and implemented a holistic integrative oncology intervention.</p></div><div><h3>Case presentation</h3><p>The patient was 59-years-old when diagnosed with Stage IV locally recurrent rectal cancer, and referred to a highly specialised centre for colorectal cancer care at a tertiary teaching hospital in Sydney, Australia. Treatment included chemo/radiotherapy, liver resection and posterior pelvic exenteration surgery. The patient's background as a health researcher and clinician optimised her ability to design and implement an integrative oncology model of care, including yoga, mindfulness, Buddhist meditation and study, social connection, exercise, psychotherapeutic and nutritional support. This paper describes these mind-body practices and lifestyle modifications and outlines her experiences and outcomes at each stage of her extensive and radical treatment.</p></div><div><h3>Conclusion</h3><p>This case provides a unique perspective into how the integration of mind-body practices and lifestyle modifications with conventional treatment can support those living with colorectal cancer.</p></div>","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":"20 5","pages":"Article 103004"},"PeriodicalIF":1.9,"publicationDate":"2024-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1550830724000843/pdfft?md5=1ea7db3899b89dba27dd4ff0d8e25931&pid=1-s2.0-S1550830724000843-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141082835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Te Maringi Mai o Hawaiiki ((Te Arawa)) , Jade Le Grice ((Te Rarawa, Ngāpuhi)) , Logan Hamley ((Ngāti Rangi)) , Cinnamon Lindsay Latimer ((Ngāpuhi, Ngāti Porou)) , Shiloh Groot ((Ngāti Uenukukōpako, Ngāti Pikiao)) , Ashlea Gillon ((Ngāti Awa, Ngāpuhi, Ngāiterangi)) , Lara Greaves ((Ngāpuhi)) , Terryann C. Clark ((Ngāti Whātua, Ngāti Wai, Ngāpuhi))
{"title":"RANGATAHI MĀORI AND THE WHĀNAU CHOCOLATE BOX: Rangatahi wellbeing in whānau contexts","authors":"Te Maringi Mai o Hawaiiki ((Te Arawa)) , Jade Le Grice ((Te Rarawa, Ngāpuhi)) , Logan Hamley ((Ngāti Rangi)) , Cinnamon Lindsay Latimer ((Ngāpuhi, Ngāti Porou)) , Shiloh Groot ((Ngāti Uenukukōpako, Ngāti Pikiao)) , Ashlea Gillon ((Ngāti Awa, Ngāpuhi, Ngāiterangi)) , Lara Greaves ((Ngāpuhi)) , Terryann C. Clark ((Ngāti Whātua, Ngāti Wai, Ngāpuhi))","doi":"10.1016/j.explore.2024.05.005","DOIUrl":"10.1016/j.explore.2024.05.005","url":null,"abstract":"<div><p>Whānau (Māori understandings of family) are comprised of unique and vital relationships that support and scaffold rangatahi (youth) wellbeing, yet are often reduced to nuclear family structures within individualised notions of wellbeing. While rangatahi contend with racialised discourses in a colonial socio-cultural context, their whānau can be an important site for mitigating these challenges, supporting rangatahi agency and wellbeing. This article explores how whānau practices inform rangatahi wellbeing, drawing upon photo-projects and interviews with 51 rangatahi and their whānau. Interviews were thematically analysed, informing four themes that drew on Māori (the Indigenous people of Aotearoa) concepts and whakataukī: te haerenga whakamua, kotahitanga, he toa takitini and tātai hono. These themes speak to the significance of vitalising relationships between rangatahi, their whānau and beyond. We outline a strengths-based activity with rangatahi and their whānau, identifying and drawing from the delightful array of whānau relationships, qualities and characteristics that may be likened to a <em>‘whānau chocolate box’</em> for rangatahi to derive influence, systems of support and inspiration for future identities and inspiration.</p></div>","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":"20 6","pages":"Article 103007"},"PeriodicalIF":1.9,"publicationDate":"2024-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1550830724000879/pdfft?md5=6f55d31ad8e7a6cb31e1299d5ebeddcf&pid=1-s2.0-S1550830724000879-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141140680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Matters of Note","authors":"Angie Lillehei","doi":"10.1016/j.explore.2024.05.006","DOIUrl":"10.1016/j.explore.2024.05.006","url":null,"abstract":"","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":"20 4","pages":"Pages 465-466"},"PeriodicalIF":2.4,"publicationDate":"2024-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141044885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Consciousness, authoritarianism, and political violence","authors":"Stephan A. Schwartz","doi":"10.1016/j.explore.2024.05.007","DOIUrl":"10.1016/j.explore.2024.05.007","url":null,"abstract":"","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":"20 4","pages":"Pages 467-469"},"PeriodicalIF":2.4,"publicationDate":"2024-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1550830724000892/pdfft?md5=4223991a39b4e583fafae988c50f3423&pid=1-s2.0-S1550830724000892-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141030013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kelly Naranjo , Christina Awada , Judith T. Zelikoff
{"title":"The effects of electronic cigarette inhalation on immune responses: Perspectives from animal model studies","authors":"Kelly Naranjo , Christina Awada , Judith T. Zelikoff","doi":"10.1016/j.explore.2024.05.008","DOIUrl":"10.1016/j.explore.2024.05.008","url":null,"abstract":"","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":"20 4","pages":"Pages 606-607"},"PeriodicalIF":2.4,"publicationDate":"2024-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141027537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Summary of a Cochrane review: Replacing salt with low-sodium salt substitutes (LSSS) for cardiovascular health in adults, children and pregnant women","authors":"Martial Sonkoue Pianta","doi":"10.1016/j.explore.2024.05.009","DOIUrl":"10.1016/j.explore.2024.05.009","url":null,"abstract":"","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":"20 4","pages":"Pages 608-609"},"PeriodicalIF":2.4,"publicationDate":"2024-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141029328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}