Explore-The Journal of Science and Healing最新文献

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IF 2.4 4区医学

Explore-The Journal of Science and Healing Pub Date : 2026-09-01 Epub Date: 2026-09-05 DOI: 10.1016/S1550-8307(26)00210-7

引用次数: 0

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IF 2.4 4区医学

Explore-The Journal of Science and Healing Pub Date : 2026-07-01 Epub Date: 2026-07-14 DOI: 10.1016/S1550-8307(26)00172-2

引用次数: 0

Unveiling untapped potential: A reevaluation of communication and intelligence in nonspeaking autistic individuals 揭示未开发的潜力：对不会说话的自闭症患者的沟通和智力的重新评估

IF 2.2 4区医学

Explore-The Journal of Science and Healing Pub Date : 2026-05-01 Epub Date: 2026-02-10 DOI: 10.1016/j.explore.2026.103342

Filma Alia Sari , Rizky Andana Pohan , Santy Andrianie , Kadek Suhardita

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IF 2.2 4区医学

Explore-The Journal of Science and Healing Pub Date : 2026-05-01 Epub Date: 2026-05-09 DOI: 10.1016/S1550-8307(26)00129-1

引用次数: 0

Hegu point acupressure for cannulation pain across fistula sites: Randomized controlled trial 合谷穴穴位按压治疗瘘管部位插管疼痛：随机对照试验。

IF 2.2 4区医学

Explore-The Journal of Science and Healing Pub Date : 2026-03-01 Epub Date: 2026-01-14 DOI: 10.1016/j.explore.2026.103324

Gülay TURGAY , Banu ÇEVİK , Yasemin ESKİGÜLEK , Işılay İNANOĞLU , Semiha KAYA

{"title":"Hegu point acupressure for cannulation pain across fistula sites: Randomized controlled trial","authors":"Gülay TURGAY , Banu ÇEVİK , Yasemin ESKİGÜLEK , Işılay İNANOĞLU , Semiha KAYA","doi":"10.1016/j.explore.2026.103324","DOIUrl":"10.1016/j.explore.2026.103324","url":null,"abstract":"<div><h3>Background</h3><div>Cannulation-related pain is a common problem in hemodialysis patients with arteriovenous fistulas (AVFs). Identifying effective non-pharmacological strategies, such as Hegu (LI4) point acupressure, may help improve patient comfort. This study examined the effect of Hegu point acupressure on cannulation-related pain in hemodialysis patients with AVFs located in different anatomical regions.</div></div><div><h3>Material and Methods</h3><div>This randomized controlled study included 131 hemodialysis patients at a university dialysis center between October 2022 and February 2023. Patients had AVFs in antecubital, Brescia-Cimino, or snuff-box regions and were randomly assigned to intervention or control groups. The intervention consisted of three minutes of Hegu acupressure before cannulation, applied across three consecutive dialysis sessions. Pain intensity during needle insertion was assessed with the Numerical Rating Scale. Control patients received routine care. Data were analyzed using mixed-design ANOVA, and effect sizes were calculated with Cohen’s d.</div></div><div><h3>Results</h3><div>Pain scores in intervention groups decreased significantly across all fistula sites, with the most pronounced reduction in the Brescia-Cimino site (from 2.18 ± 0.95 to 0.81 ± 0.20). Decreases were also observed in the antecubital (from 2.14 ± 1.08 to 1.13 ± 0.46) and snuff-box sites (from 1.82 ± 0.13 to 1.09 ± 0.86). In contrast, pain scores in control groups remained stable or increased. Group and time interaction effects were significant across all sites (<em>p</em> < 0.05), with large effect sizes favoring acupressure.</div></div><div><h3>Conclusion</h3><div>Hegu point acupressure reduced cannulation pain in patients with AVFs at different anatomical sites, with the strongest effect in the Brescia-Cimino region.</div></div>","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":"22 2","pages":"Article 103324"},"PeriodicalIF":2.2,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146030318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of inhaled peppermint essential oil aromatherapy on postoperative nausea and vomiting in patients undergoing laparoscopic gynecologic surgery 吸入薄荷精油芳香疗法对腹腔镜妇科手术患者术后恶心呕吐的影响

IF 2.2 4区医学

Explore-The Journal of Science and Healing Pub Date : 2026-03-01 Epub Date: 2026-01-13 DOI: 10.1016/j.explore.2026.103321

Hai Tang , Mengyu Liu , Zijian Zhou , Hui Liu , Zhijie Ji , Min Yang , Jinfeng Shen , Maoyin Zhang

{"title":"Effect of inhaled peppermint essential oil aromatherapy on postoperative nausea and vomiting in patients undergoing laparoscopic gynecologic surgery","authors":"Hai Tang , Mengyu Liu , Zijian Zhou , Hui Liu , Zhijie Ji , Min Yang , Jinfeng Shen , Maoyin Zhang","doi":"10.1016/j.explore.2026.103321","DOIUrl":"10.1016/j.explore.2026.103321","url":null,"abstract":"<div><h3>Background</h3><div>This study evaluated the effect of inhaled peppermint essential oil (PEO) aromatherapy on postoperative nausea and vomiting (PONV) in patients undergoing laparoscopic gynecologic surgery.</div></div><div><h3>Methods</h3><div>In this randomized controlled trial, 106 patients were assigned to either the PEO group or normal saline (NS) group. The PEO group received inhalational aromatherapy with 2% peppermint oil before induction, preoperatively, and immediately after extubation. The NS group received an identical intervention using 2 ml of 0.9% sodium chloride solution.</div></div><div><h3>Results</h3><div>Compared with the NS group, the PEO group had a significantly lower incidence of PONV within 24 h (52.8% vs. 73.6%; <em>p</em> = 0.043). The reduction was most notable during the first hour (45.3% vs. 73.6%; <em>p</em> = 0.047). The PEO group also demonstrated significantly improved anxiety scores at 0–24 h and 24–48 h, reduced pain catastrophizing, and decreased abdominal distension.</div></div><div><h3>Conclusion</h3><div>Inhaled peppermint aromatherapy reduced the incidence of PONV, improved anxiety, decreased pain catastrophizing, and alleviated abdominal distension in patients undergoing laparoscopic gynecological surgery.</div></div><div><h3>Clinical Trial Registration</h3><div>This study was registered in the Chinese Clinical Trial Registry. (Registration number: ChiCTR2400093289 Registration Date:2024–12–02)</div></div>","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":"22 2","pages":"Article 103321"},"PeriodicalIF":2.2,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145979382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Improvement in postural imbalance with intake of resveratrol (polyphenolic phytoalexin) in patients of knee osteoarthritis 膝关节骨关节炎患者摄入白藜芦醇（多酚植物抗毒素）后姿势失衡的改善。

IF 2.2 4区医学

Explore-The Journal of Science and Healing Pub Date : 2026-03-01 Epub Date: 2026-02-04 DOI: 10.1016/j.explore.2026.103341

Asima Karim , Haroon Ahmed Khan , Firdos Ahmad , Rizwan Qaisar

{"title":"Improvement in postural imbalance with intake of resveratrol (polyphenolic phytoalexin) in patients of knee osteoarthritis","authors":"Asima Karim , Haroon Ahmed Khan , Firdos Ahmad , Rizwan Qaisar","doi":"10.1016/j.explore.2026.103341","DOIUrl":"10.1016/j.explore.2026.103341","url":null,"abstract":"<div><h3>Purpose</h3><div>Knee osteoarthritis (OA) and postural imbalance are interlinked, increasing fall risk in older adults. The effective therapeutic approach remains unclear.</div></div><div><h3>Objective</h3><div>To investigate how resveratrol, a natural stilbene compound, influences balance disturbances in individuals with knee OA</div></div><div><h3>Method</h3><div>In a randomized double blind clinical trial, 129 patients with OA were allocated to receive either placebo (<em>n</em> = 67) or resveratrol at a daily dose of 500 mg (<em>n</em> = 62) for 18 weeks. Assessments included Oxford Knee Score (OKS), WOMAC index, knee flexion range of motion (ROM), gait speed, handgrip strength, balance scores, and plasma concentrations of SIRT1 and C-reactive protein (CRP), recorded at baseline and again after 18 weeks.</div></div><div><h3>Results</h3><div>Resveratrol significantly improved balance, gait speed, knee ROM, HGS, and reduced pain during walking and WOMAC scores (all <em>p</em> < 0.05), without affecting OKS or resting pain. Plasma SIRT1 increased, and CRP decreased in the resveratrol group. SIRT1 levels correlated strongly with balance scores post-treatment (r²=0.322, <em>p</em> < 0.0001), more than in placebo (r²=0.084, <em>p</em> = 0.017) or baseline values.</div></div><div><h3>Conclusion</h3><div>Resveratrol alleviated OA symptoms and postural imbalance, potentially through anti-inflammatory effects mediated by elevated plasma SIRT1.</div></div>","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":"22 2","pages":"Article 103341"},"PeriodicalIF":2.2,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146183247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correlations between onsite and global networks of random number generators during group healing meditations 在群体治疗冥想中，现场和全球随机数生成器网络之间的相关性

IF 2.2 4区医学

Explore-The Journal of Science and Healing Pub Date : 2026-03-01 Epub Date: 2025-12-27 DOI: 10.1016/j.explore.2025.103312

Nachum Plonka , Scott Davies , Mike Atkinson , Kevin Crowe , Joe Dispenza , Rollin McCraty

{"title":"Correlations between onsite and global networks of random number generators during group healing meditations","authors":"Nachum Plonka , Scott Davies , Mike Atkinson , Kevin Crowe , Joe Dispenza , Rollin McCraty","doi":"10.1016/j.explore.2025.103312","DOIUrl":"10.1016/j.explore.2025.103312","url":null,"abstract":"<div><h3>Introduction</h3><div>The Global Consciousness Project 2.0 (GCP 2.0) is an initiative investigating the relationship between human consciousness and the behavior of the project’s random number generators (RNGs). This was explored via a series of meditation workshops led by Dr. Joe Dispenza with between 1000-2200 participants. They are run almost monthly and include meditative practices and 3 separate Coherence Healing meditations, the high points of the events.</div></div><div><h3>Methods</h3><div>At all of the events in the first half of 2024, a tower of 40 RNGs in GCP 2.0 devices had been placed in the meditation room, constituting a local RNG network. Their data was compared to that of the hundreds of RNGs distributed across the globe, constituting a global network. All outputs were rigorously processed and tested to ensure randomness. In this exploratory study, each of the local and global networks were analyzed for Network Coherence, a measure of coherent activity across RNGs.</div></div><div><h3>Results</h3><div>During the 15 healing meditations, a significant correlation was observed between the Network Coherence of the global and local networks, with a mean correlation of 0.27 (p < 0.01). As this occurred only during healing meditations and not at other times, it suggests the highly focused attention and/or elevated emotional state across humans in the room may have measurable global impact, demonstrating the reach of a small coherent group. Also, combining the local RNG Network Coherence across all the healing meditation periods via a Stouffer’s Z score resulted in a distinctive curve when plotted, resembling an evoked response. This suggests a mechanism whereby a coherently focused signal from the people in the room evokes a response from the RNGs similar to those observed in evoked potentials in the brain.</div></div>","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":"22 2","pages":"Article 103312"},"PeriodicalIF":2.2,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145886051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sleep and brain-gut-microbiota interaction 睡眠与大脑-肠道微生物群的相互作用。

IF 2.2 4区医学

Explore-The Journal of Science and Healing Pub Date : 2026-03-01 Epub Date: 2026-01-08 DOI: 10.1016/j.explore.2026.103314

Angie Lillehei

引用次数: 0

Herbal decoction with post-surgery for tibiofibular fracture: A systematic review 中药汤剂治疗胫腓骨骨折：系统综述

IF 2.2 4区医学

Explore-The Journal of Science and Healing Pub Date : 2026-03-01 Epub Date: 2026-01-21 DOI: 10.1016/j.explore.2026.103327

Jiho Pyun , Manki Hwang , Taekyu Yang , Sungeun Kwon , Yoonchul Jung , Changsub Yeum , Seung-Hun Cho

{"title":"Herbal decoction with post-surgery for tibiofibular fracture: A systematic review","authors":"Jiho Pyun , Manki Hwang , Taekyu Yang , Sungeun Kwon , Yoonchul Jung , Changsub Yeum , Seung-Hun Cho","doi":"10.1016/j.explore.2026.103327","DOIUrl":"10.1016/j.explore.2026.103327","url":null,"abstract":"<div><h3>Introduction</h3><div>We evaluated the efficacy and safety of Taohong Siwu decoction (THSWD) as an adjunct to the usual therapy after surgery for tibiofibular fractures.</div></div><div><h3>Methods</h3><div>We conducted a comprehensive literature search across seven databases (MEDLINE [via PubMed], Embase, CENTRAL, CNKI, Wanfang, Sinomed, and CiNii) for relevant articles published from database inception through July 9, 2025. Meta-analyses were performed using a random-effects model. Depending on the outcome types, the results are reported as risk ratios (RRs), odds ratios (ORs), or mean differences (MDs), each with their corresponding 95% confidence intervals (CIs).</div></div><div><h3>Results</h3><div>We included 24 randomized controlled trials involving 2,048 participants. Compared to treatment as usual (TAU) alone, combined THSWD and TAU was associated with improvements in pain (MD -1.34; 95% CI -1.79 to -0.88, I² = 97%), time to fracture healing (MD -3.68; 95% CI -5.37 to -1.99, I² = 95%), the Hospital for Special Surgery Knee-Rating Scale score (MD 9.00; 95% CI 5.61 to 12.40), and the clinical response (RR = 1.16; 95% CI 1.12 to 1.21). The OR for adverse events was also significantly lower (OR 0.13; 95% CI 0.07 to 0.26) with THSWD combined with TAU. However, the included trials generally had low methodological quality, as assessed by RoB 2.0.</div></div><div><h3>Conclusion</h3><div>THSWD may serve as an effective adjunctive therapy to TAU to enhance recovery after tibiofibular fracture surgery, although the certainty of the evidence remains low, while potentially reducing adverse events.</div></div><div><h3>Systematic Review Registration</h3><div><span><span>www.crd.york.ac.uk/prospero</span><svg><path></path></svg></span> (CRD420251107355)</div></div>","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":"22 2","pages":"Article 103327"},"PeriodicalIF":2.2,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146078338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0