Explore-The Journal of Science and Healing最新文献

{"title":"Corrigendum to “The effect of Helfer skin tap technique on hepatitis B vaccine intramuscular injection pain in neonates: A randomized controlled trial” [EXPLORE, 19 (2023) 238-242]","authors":"Şefika Dilek Güven , Nazan Çakırer Çalbayram","doi":"10.1016/j.explore.2025.103135","DOIUrl":"10.1016/j.explore.2025.103135","url":null,"abstract":"","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":"21 2","pages":"Article 103135"},"PeriodicalIF":1.9,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143436472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Infra-low frequency neurofeedback impact on post-concussive symptoms of headache, insomnia and attention disorder: Results of a randomized control trial","authors":"Judy Carlson ,&nbsp;G․Webster Ross ,&nbsp;Caitlin Tyrrell ,&nbsp;Belkys Fiame ,&nbsp;Courtnee Nunokawa ,&nbsp;Chathura Siriwardhana ,&nbsp;Kim Schaper","doi":"10.1016/j.explore.2025.103137","DOIUrl":"10.1016/j.explore.2025.103137","url":null,"abstract":"<div><div>The purpose of this study was to ascertain the impact infra-low-frequency neurofeedback (ILF NFB), a new paradigm in the field, has on post-concussive symptoms of headache, sleep and attention disorders experienced by combat Veterans.</div></div><div><h3>Background</h3><div>ILF NFB, a non-invasive integrative health intervention, has demonstrated clinical efficacy in treating several physical and psychological conditions, including headaches, dysregulated sleep, and attentional dysfunctions. Given that 20–40 % of combat Veterans who experienced concussions during recent military operations suffer chronically from these disorders, this study aims to determine whether ILF NFB might be an effective treatment option.</div></div><div><h3>Methods</h3><div>Eighty-seven participants were enrolled in this randomized controlled trial, with 36 completing the intervention (Twenty 1/2-hour sessions of ILF NFB and 4 assessment sessions) and 38 completing the control procedures (8 weekly 15-minute health related discussions and 4 assessment sessions). Both groups continued treatment as usual throughout participation in study. Data were analyzed on intent to treat principle.</div></div><div><h3>Results</h3><div>Eighty-six percent of the participants were male and 14 % female, mean age was 45 for both groups. When comparing baseline to end of treatment measures, findings were clinically and statistically significant for headache (&lt;0.0001), sleep (&lt;0.0001) and attention (0.0022). Additional variables of interest were also significantly improved following ILF NFB, including quality of life (<em>p</em> &lt; .0001), depressive symptoms (<em>p</em> &lt; .0001), and symptoms of posttraumatic stress disorder (<em>p</em> = .0001).</div></div><div><h3>Conclusion</h3><div>ILF NFB holds promise to be a safe and effective intervention for those who suffer with post-concussive symptoms of chronic headache, sleep, and attention disorders.</div></div>","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":"21 2","pages":"Article 103137"},"PeriodicalIF":1.9,"publicationDate":"2025-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143436473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of olive leaf extract on pain management and functional improvement in elderly patients with knee osteoarthritis: A randomized controlled trial","authors":"Marjan Roshani ,&nbsp;Bahram Delfan ,&nbsp;Sajad Yarahmadi ,&nbsp;Mandana Saki ,&nbsp;Mehdi Birjandi","doi":"10.1016/j.explore.2025.103136","DOIUrl":"10.1016/j.explore.2025.103136","url":null,"abstract":"<div><h3>Introduction</h3><div>Osteoarthritis is a progressive joint disease that affects one or more joints, leading to restricted movement, pain, and eventual disability. Despite the availability of various treatments and supportive care, managing osteoarthritis symptoms remains challenging. This study aimed to evaluate the effect of Hydroalcoholic olive leaf extract on pain reduction and daily functioning in elderly patients with knee osteoarthritis.</div></div><div><h3>Method</h3><div>A randomized, controlled, factorial clinical trial was conducted in 2022–2023 with 100 elderly participants suffering from knee osteoarthritis. Participants were selected through consecutive sampling and randomly assigned to four groups using block-stratified randomization. In addition to routine treatment, participants in group I received topical olive leaf extract ointment, Group II received oral olive leaf extract capsules, and Group III received a combination of both treatments. The intervention was administered three times daily for eight weeks. The control group did not receive any olive leaf extract-based interventions. Pain intensity was assessed using a visual analog scale, and daily functioning and joint stiffness were measured using the Western Ontario and McMaster Universities Osteoarthritis Index questionnaire. Data were analyzed using SPSS software.</div></div><div><h3>Results</h3><div>The intervention groups showed significantly more significant reductions in mean pain scores than the control group (<em>p</em> &lt; 0.05). The combination of oral capsules and topical ointment among the intervention groups demonstrated the most pronounced pain reduction. The mean score for daily functioning improved significantly over time in all groups (<em>p</em> = 0.007). A decrease of 1.19 units per time increment was observed in the group using the ointment, while the oral capsule group showed a decrease of 0.89 units, both statistically significant (<em>p</em> = 0.006).</div></div><div><h3>Conclusion</h3><div>Hydroalcoholic olive leaf extract effectively reduces pain and improves physical functioning in elderly patients with knee osteoarthritis, offering a promising complementary treatment option for managing osteoarthritis symptoms.</div></div>","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":"21 2","pages":"Article 103136"},"PeriodicalIF":1.9,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143420144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of plaster applied to the umbilical area (Shenque-CV8 point) on nausea and vomiting during pregnancy","authors":"Yasemin Hamlaci Başkaya ,&nbsp;Kevser Çimen Coskun ,&nbsp;Güleser Ada ,&nbsp;Kevser Ilçioğlu ,&nbsp;Osman Esen","doi":"10.1016/j.explore.2025.103133","DOIUrl":"10.1016/j.explore.2025.103133","url":null,"abstract":"<div><h3>Background</h3><div><strong>:</strong> Hormonal and physical changes, especially in the first trimester of pregnancy, can cause nausea and vomiting.</div></div><div><h3>Aim</h3><div><strong>:</strong> This study aims to investigate the effect of plaster applied to the umbilical area (Shenque-CV8 point) on nausea and vomiting during pregnancy.</div></div><div><h3>Methods</h3><div><strong>:</strong> It is a randomized-controlled study (Clinical trial number: NCT05788796). A total of 60 pregnant women, 30 in the CV8 group and 30 in the control group constituted the sampling of the study. Pregnant women in the CV8 group were regularly asked to fix a hazelnut-sized cotton ball to the umbilicus with plaster before going to bed at night for five days. Pregnant women in the control group were not asked to make any changes in their lives. The nausea-vomiting levels of pregnant women before and five days after the treatment were compared using the Rhodes Nausea Index and PUQE nausea scoring. The data was analyzed by the independent sample <em>t</em>-test, chi-square test, and paired sample <em>t</em>-test. The statistical significance value was accepted as <em>P</em> &lt; 0.05.</div></div><div><h3>Results</h3><div><strong>:</strong> There was no statistically significant difference between the experiment and control groups in terms of sociodemographic and obstetric characteristics. The degree of nausea decreased in the experiment group compared to the pre-intervention period (<em>p</em> &lt; 0.001), while no statistically significant change was found in the control group. In addition, while there was no difference between the two groups in terms of nausea scores before the application, there was a statistically significant difference between the two groups after the application, the nausea score of the experimental group was lower compared to the control group (<em>p</em> &lt; 0.05).</div></div><div><h3>Conclusion</h3><div><strong>:</strong> The results show that the application of plaster to the Shenque-CV8 point reduces nausea and vomiting in pregnant women and has no side effects. This application is practical, non-invasive, and easy to apply.</div></div>","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":"21 2","pages":"Article 103133"},"PeriodicalIF":1.9,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143076094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The beneficial effects of the herbal medicine Di-Huang-Yin-Zi on patients with traumatic cauda equina injury: A randomized, double-blind, placebo-controlled study","authors":"Mei Yu ,&nbsp;Pi-Zhen Zu ,&nbsp;Li-Yang Guo ,&nbsp;Qing-Hua Zhang ,&nbsp;Lian-Tao Li","doi":"10.1016/j.explore.2025.103134","DOIUrl":"10.1016/j.explore.2025.103134","url":null,"abstract":"<div><h3>Objective</h3><div>This study aimed to investigate the safety and efficacy of Di-Huang-Yin-Zi (DHYZ), also known as Rehmanniae Yin-Zi, a traditional Chinese medicinal formula used for treating of neurological disorders in patients with traumatic cauda equina injury (TCEI).</div></div><div><h3>Methods</h3><div>In this double-blind, placebo-controlled study, TCEI patients with American Spinal Injury Association (ASIA) impairment grades C were randomized to receive either DHYZ (<em>n</em> = 30) or placebo (<em>n</em> = 30) for 8 weeks. Both groups also received rehabilitation therapy and oral mecobalamine therapy during the treatment. Motor and sensory functions, as well as walking ability, were assessed biweekly.</div></div><div><h3>Results</h3><div>At the end of the treatment, the DHYZ group exhibited significantly higher scores in sensory and motor function, as well as walking ability, compared to the placebo group (all <em>P</em> &lt; 0.05). Additionally, no serious side effects were reported.</div></div><div><h3>Conclusion</h3><div>DHYZ has the potential to accelerate nerve repair and may serve as an effective adjuvant therapy to enhance the recovery of nerve function in patients with TCEI.</div></div>","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":"21 2","pages":"Article 103134"},"PeriodicalIF":1.9,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143103557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An integrative Chinese herbal medicine and ointment therapy for bullous pemphigoid: A case report","authors":"Ming-Huei Cheng ,&nbsp;Yu-Yun Chen ,&nbsp;Deng-Ho Yang ,&nbsp;Yi-Shu Liao ,&nbsp;Feng-Ling Liu ,&nbsp;Hui-Min David Wang ,&nbsp;Hung-Rong Yen","doi":"10.1016/j.explore.2025.103132","DOIUrl":"10.1016/j.explore.2025.103132","url":null,"abstract":"<div><div>Pemphigoid disorders are autoimmune bullous dermatoses with a high mortality rate of up to 40 %, associated with many complications during hospitalization, even when treated with conventional therapies such as steroids, oral antibiotics, and steroid-sparing immunosuppressants. We present a continuous case monitoring a patient with a medical history of oral diabetic medication, who was diagnosed with bullous pemphigoid on December 26, 2023. Despite treatment with an immunomodulator (hydroxychloroquine), antihistamines, injectable and oral steroids, analgesics, antibiotics, and antibiotic ointment, the patient's symptoms of blisters, erosions, and ulcerations persisted severely. Consequently, Chinese Herbal Medicine (CHM) and Chinese Herbal Medicine Ointment (CHMO) were prescribed for the patient from January 5, 2024, to February 23, 2024. After the combined therapy of Chinese herbal medicine and ointment with conventional treatment, the patient's blisters, erosions, ulcerations, inflammation, and the development of new lesions were alleviated. This case suggests that an integrative approach combining Chinese herbal medicine and ointment with Western medical treatment could be a cost-effective option for improving the prognosis of bullous pemphigoid patients.</div></div>","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":"21 2","pages":"Article 103132"},"PeriodicalIF":1.9,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143329584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Alexander technique for older adults-An evidence based low-cost method for chronic pain and frailty prevention.","authors":"Mikhail Kogan, Anna Furman","doi":"10.1016/j.explore.2025.103131","DOIUrl":"https://doi.org/10.1016/j.explore.2025.103131","url":null,"abstract":"","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":" ","pages":"103131"},"PeriodicalIF":1.9,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143257215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Auriculotherapy may help to reduce gastrointestinal reactions and improve quality of life post chemotherapy","authors":"Qiao Xiao,&nbsp;Tingting Liu,&nbsp;Jiawei Li,&nbsp;Zhiling Sun","doi":"10.1016/j.explore.2025.103129","DOIUrl":"10.1016/j.explore.2025.103129","url":null,"abstract":"<div><h3>Aim</h3><div>To compare the effectiveness of auriculotherapy in managing nausea and vomiting caused by platinum-based chemotherapy</div></div><div><h3>Methods</h3><div>96 patients with gastrointestinal cancer undergoing platinum chemotherapy were randomly divided into three groups, with 32 patients in each group. The control group received conventional treatment, including 5-hydroxytryptamine 3 receptor antagonist and routine nursing care; the remaining two groups received additional auricular point sticking or ear scraping. The outcomes measured included the incidence and frequency of acute and delayed nausea and vomiting, severity of nausea, appetite, and quality of life function index 24 h and 5 d post chemotherapy.</div></div><div><h3>Results</h3><div>Statistically significant differences were observed in the incidence and frequency of acute and delayed nausea and vomiting, severity of nausea, appetite, and life function index of nausea and vomiting at 24 h and 5 d post chemotherapy (<em>P</em> &lt; 0.05); the efficacy of treatment in the ear scraping and auricular point sticking groups was better than that of the control group (<em>P</em> &lt; 0.05). Moreover, the ear scraping group experienced a more effective reduction in acute nausea and vomiting than that in the auricular point sticking group (<em>P</em> &lt; 0.05), and auricular point sticking showed better results in managing delayed nausea and vomiting and improving appetite and quality of life 5 d post chemotherapy (<em>P</em> &lt; 0.05).</div></div><div><h3>Conclusions</h3><div>Auricular point sticking and ear scraping effectively treat chemotherapy-induced nausea and vomiting (CINV). Ear scraping is more effective for acute CINV, whereas auricular point sticking is more effective for delayed CINV, with the distinct advantages of enhancing appetite and quality of life for each type of CINV.</div></div>","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":"21 2","pages":"Article 103129"},"PeriodicalIF":1.9,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143061233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of Reiki on anxiety level in mothers of hospitalized children: A randomized-controlled study","authors":"Şükran Başgöl,&nbsp;Sümeyye Bal,&nbsp;Emine Koç","doi":"10.1016/j.explore.2025.103128","DOIUrl":"10.1016/j.explore.2025.103128","url":null,"abstract":"<div><h3>Context</h3><div>Reiki is considered an effective, side-effect-free, and non-invasive method to alleviate anxiety.</div></div><div><h3>Objective</h3><div>This study aimed to investigate the effect of Reiki on the anxiety levels of mothers with hospitalized children.</div></div><div><h3>Method</h3><div>This three-arm parallel randomized controlled trial included 120 mothers with hospitalized children who were divided into 3 equal-sized groups. Over 2 weeks, the Reiki group (n = 40) received 4 sessions (45 minutes each) of Reiki, the placebo group (n = 40) received sham Reiki, and the control group (n = 40) received no intervention. The anxiety levels of the participants were assessed using the State-Trait Anxiety Inventory (STAI-S) before and after the intervention.</div></div><div><h3>Results</h3><div>After receiving four Reiki sessions over two weeks, the anxiety levels of those in the Reiki group were statistically significantly lower than those in the placebo and control groups (Reiki group 43.25 ± 2.93, placebo group 51.13 ± 12.15, and control group 51.03 ± 9.27; p = 0.001). Regarding the intragroup STAI-S score changes, only the mean pre-intervention score of the Reiki group was higher compared to the post-test score, and this difference was statistically significant (t = 4.209, p = 0.001). There was no statistically significant difference between the pre-test and post-test scores of the placebo and control groups (p &gt; 0.05).</div></div><div><h3>Conclusions</h3><div>The results of the study suggested that Reiki treatment significantly reduced the anxiety levels of the mothers with hospitalized children who received it compared to those who did not (the placebo and control groups).</div></div>","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":"21 2","pages":"Article 103128"},"PeriodicalIF":1.9,"publicationDate":"2025-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143015440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Explore the application effect of acupoint massage combined with ear point pressing beans in the remission stage of asthma","authors":"Xiaoye Sun ,&nbsp;Qun Kang ,&nbsp;Haiyan Zhu ,&nbsp;Xiaohong Chu","doi":"10.1016/j.explore.2025.103116","DOIUrl":"10.1016/j.explore.2025.103116","url":null,"abstract":"<div><h3>Objective</h3><div>To explore the application effect of acupoint massage combined with ear point pressing beans in the remission stage of bronchial asthma.</div></div><div><h3>Methods</h3><div>A total of 120 children with asthma in remission who were treated in the paediatric outpatient department between January 2016 and October 2022 were randomly divided into the experimental and control groups, with 60 patients in each group. The patients in both groups were treated with salmeterol and fluticasone inhalation powder, 1 puff each time, twice a day. The patients in the control group received acupoint massage in addition to this treatment, with acupoint massage performed once a day, Monday to Friday, lasting 30 min each time. The patients in the experimental group received ear point pressing beans in addition to the treatment in the control group. Ear point press bean paste bean once a week,press 3-5 times a day,press each point for i minute. Changes in pulmonary function and asthma control were observed before and after treatment in both groups, with forced expiratory volume in 1 second (FEV1), forced expiratory vital capacity (FVC), FEV1/FVC ratio and the Asthma Control Test (ACT) score compared.</div></div><div><h3>Results</h3><div>After 8 weeks of treatment, FEV1, FVC, FEV1/FVC ratio and the ACT scores of both groups improved to different degrees (<em>P</em> <em>&lt;</em> <em>0.05</em>). In terms of the effective control rate, the total clinical effective control rate (95 %) of patients in the experimental group was significantly higher than that in the control group (81.67 %) (<em>P</em> &lt; 0.05).</div></div><div><h3>Conclusion</h3><div>Acupoint massage combined with ear point pressing beans has a good effect on the treatment of asthma remission and can effectively improve the quality of life, making it worthy of further promotion in clinical practice.</div></div>","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":"21 2","pages":"Article 103116"},"PeriodicalIF":1.9,"publicationDate":"2025-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143349040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}