Asian Journal of Pharmaceutical and Clinical Research最新文献

{"title":"ROLE OF DYNAMIZATION IN INTRAMEDULLARY NAILING OF TIBIA","authors":"Daljinder Singh, Kshitij Mehta, Harmanpreet Sandhu, Dharminder Singh, Girish Sahni","doi":"10.22159/ajpcr.2024.v17i5.50246","DOIUrl":"https://doi.org/10.22159/ajpcr.2024.v17i5.50246","url":null,"abstract":"Objectives: This study aims to know the functional outcomes of intramedullary nailing (IMN) osteosynthesis in long bone shaft fractures among adult patients with stable internal fixation and union. Additionally, it seeks to assess the specific and general complications experienced by both groups.\u0000Methods: The study was conducted at the Department of Orthopedics, Government Medical College, and Rajindra Hospital in Patiala, spanning from March 2021 to December 2022. It was a prospective, manipulative, controlled study involving a total of 40 cases of tibia diaphyseal fractures that were presented to the orthopedics department. Fractures were classified according to the AO fracture classification.\u0000Results: The average time for union in the dynamic group was 15.60 weeks (with a standard deviation of 1.27). A significant statistical difference was observed, favoring the dynamization nailing group (p<0.01), indicating a strong trend toward faster union. Out of the 40 patients, 16 (40%) experienced at least one complication. In conclusion, dynamic IMN osteosynthesis permits micromotion between fracture fragments, directly stimulating bone formation and the development of callus.\u0000Conclusion: For closed or open tibial diaphyseal fractures with minimal comminution (types A and B based on the AO classification) up to Gustilo 3A, dynamic IMN assembly is considered a safe and effective treatment option.","PeriodicalId":504156,"journal":{"name":"Asian Journal of Pharmaceutical and Clinical Research","volume":"1 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141003926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"HAEMATOLOGICAL PROFILE AND MENTZER INDEX IN PEDIATRIC PATIENTS PRESENTING WITH ANEMIA","authors":"Aditya Aggarwal, Amit Kumar Modi, R. K, Avinash Kumar Jha","doi":"10.22159/ajpcr.2024.v17i5.51128","DOIUrl":"https://doi.org/10.22159/ajpcr.2024.v17i5.51128","url":null,"abstract":"Objective: The objective of this study was to analyze clinical and hematological profile of children with anemia and determine the Mentzer index of all cases presenting with anemia.\u0000Methods: This was a cross-sectional observational study conducted in the Department of pediatrics of a tertiary care medical college. Eighty pediatric age group patients diagnosed to be having anemia on clinical examination were included in this study. Demographic details such as age and gender were noted in all cases. A through history was obtained and a clinical examination was done. Presenting complaints were also noted. Complete blood count with peripheral blood smear examination was done in all cases. The Mentzer index was determined from complete blood count reports.\u0000Results: Out of 80 studied cases, there were 57 (71.25%) boys and 23 (28.75%) girls. The mean age for boys was 9.12±3.14 years and for girls, it was slightly higher at 10.24±3.46 years. Fatigue (73.75%), pallor (71.25%), and anorexia (56.25%) were common complaints. About 55% had mild anemia 22.5% had moderate anemia and 22.5% suffered from severe. Mean hemoglobin concentration of studied cases was found to be 8.42±3.98 g/dL. The most prevalent blood picture was the normocytic normochromic blood picture, representing 60% of cases. Mentzer index ranged from a minimum of 10.83 to a maximum of 27.76, with the mean value being 17.40±2.92. Notably, the vast majority of patients (97.5%) had a Mentzer Index >13, suggesting a high prevalence of iron deficiency. Conversely, only 2.5% of the patients had a Mentzer Index at or below 13, indicating a much smaller subset in whom Hb electrophoresis was needed to rule out thalassemia trait.\u0000Conclusion: Although most of the children with anemia are secondary to iron deficiency Mentzer index should be determined in all patients of anemia so as to avoid inadvertently prescribing iron supplementation in cases of thalassemia trait.","PeriodicalId":504156,"journal":{"name":"Asian Journal of Pharmaceutical and Clinical Research","volume":"2 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141004838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"IMPLEMENTING “BUNDLED INTERVENTIONS” IN REDUCING SURGICAL SITE INFECTIONS AMONG PATIENTS UNDERGOING SURGERY FOR GYNECOLOGICAL INDICATIONS – A PROSPECTIVE STUDY","authors":"Puja Jain Dewan, Rashmi Pilania, Monika Singh, Rohini","doi":"10.22159/ajpcr.2024.v17i5.50099","DOIUrl":"https://doi.org/10.22159/ajpcr.2024.v17i5.50099","url":null,"abstract":"Objective: Surgical site infection (SSI) is the most common infection among surgical patients. This study evaluated the impact of bundled interventions in reducing SSI rates in gynecological surgery. Therefore, it is a vital tool to improve patient safety.\u0000Methods: One hundred study participants were taken in the tertiary care hospital and divided into Group I and Group II. In Group I, 50 patients were involved in elective OT with bundled interventions, and in Group II, 50 controls operated in identical OT without bundled intervention. Incidence of SSI, type of SSI, antibiotic usage, need for secondary suturing, duration, etc., was noticed.\u0000Results: Our findings showed that six out of fifty cases developed the symptoms with a 10% SSI rate. Two had superficial SSI, and three had deep SSI. None of the patients had organ space SSI. In the control group, the SSI rate was 12%. The bundled intervention was associated with a significant reduction in infection rate.\u0000Conclusion: The study indicates that SSIs are associated with severe morbidity and mortality. It is a straightforward, feasible approach to the reduction of the SSI rate.","PeriodicalId":504156,"journal":{"name":"Asian Journal of Pharmaceutical and Clinical Research","volume":"10 18","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141004786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"DEPRESSION IN FAMILY MEMBERS OF ALCOHOL DEPENDENCE PATIENTS: AN OBSERVATIONAL STUDY","authors":"Piyush Mahajan, Malvika Dahuja","doi":"10.22159/ajpcr.2024.v17i5.50987","DOIUrl":"https://doi.org/10.22159/ajpcr.2024.v17i5.50987","url":null,"abstract":"Objectives: The aim of the study was to find out prevalence and severity of depression in family members of alcohol-dependence patients.\u0000Methods: This was a cross-sectional, observational study in which 50 family members of patients with alcohol dependence according to mental and behavioral disorders diagnostic criterion for research (ICD-10 DCR) included on the basis of a predefined inclusion and exclusion criteria. The severity of alcohol dependence was assessed by Alcohol Use Disorders Identification Test-C (AUDIT-C) score. The incidence of depression and its severity in family members was assessed by Hamilton Rating Scale for Depression (HAM-D) score. The correlation of AUDIT-C score in alcohol-dependent patients and HAM-D score in family members was done by using Pearson coefficient correlation statistical purposes p<0.05 was considered as statistically significant.\u0000Results: Out of the 50 patients with alcohol dependence, 48 (96.00%) were males and 2 (4%) were females. The mean age of the patients was found to be 41.12±11.02. The mean duration of alcoholism was 8.16±5.39 years. 19 (38%) patients had AUDIT-C score of 8 whereas AUDIT-C score of 10 and 12 was found in 16 (32%) and 15 (30%) patients each. The most commonly affected relative was spouse (40%), followed by mother (26%), brother (20%), and father (14%). Majority of the family members (82%) had mild depression (score between 8 and 13). Nine (18%) patients did not have any depression. Moderate, severe, or very severe depression was not seen in any family member. There was a significant positive correlation between AUDIT-C score in alcohol-dependent patients and HAM-D score in family members (R score=0.6333 and p<0.005).\u0000Conclusion: There is a significant psychological impact, particularly depression, of alcohol dependence on family members. Severity of hazardous drinking correlated positively with the incidence of depression in family members.","PeriodicalId":504156,"journal":{"name":"Asian Journal of Pharmaceutical and Clinical Research","volume":"96 s391","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141003009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"PHENOTYPIC DETECTION OF ESBL AND AMPC BETA LACTAMASES AMONG GRAM-NEGATIVE ISOLATES FROM CLINICAL SAMPLES IN A TERTIARY CARE HOSPITAL","authors":"Dasari Bhavana, Shabnum Musaddiq, SAILEELA K","doi":"10.22159/ajpcr.2024.v17i5.50385","DOIUrl":"https://doi.org/10.22159/ajpcr.2024.v17i5.50385","url":null,"abstract":"Objectives: Drug-resistant Gram-negative bacilli expressing extended-spectrum beta-lactamases (ESBLs) and AmpC pose a serious therapeutic threat in nosocomial infections. Cost-effective screening methods are a boon to patients. This study aims to detect gram-negative bacilli and their antibiotic sensitivity patterns, as well as detect the ESBL and AmpC-producing isolates among Gram-negative bacilli.\u0000Methods: A prospective study was conducted with 150 samples. Gram-negative bacilli were isolated, and their antibiotic sensitivity tests were performed by the Kirby–Bauer disk diffusion method. Potential ESBL producers were screened using Ceftazidime disc, and AmpC producers were screened by Cefoxitin discs by the disc diffusion method. ESBL producers were confirmed by the combined disc diffusion assay method using ceftazidime and ceftazidime/Clavulanic acid disc. AmpC producers were confirmed by the Cefoxitin Cloxacillin Double Disc Synergy Test.\u0000Results: About 38% of 150 samples were gram-negative bacilli, of which 40.35% were Escherichia coli, followed by Pseudomonas aeruginosa (35.08%). Maximum sensitivity by E. coli was found toward imipenem, meropenem, and cotrimoxazole. P. aeruginosa showed maximum sensitivity toward piperacillin/tazobactam, imipenem, meropenem, and ceftazidime. 28.07% of Gram-negative isolates were ESBL producers, with E. coli (11 isolates) being the maximum, and 15.78% were AmpC producers, with E. coli (four isolates) being the maximum. Seven isolates were both ESBL and AmpC producers.\u0000Conclusion: Routine screening and timely reporting of ESBL and AmpC producers help in preventing the spread of multidrug-resistant strains. Antibiotic resistance surveillance helps in the implementation of strict infection control and prevention practices.","PeriodicalId":504156,"journal":{"name":"Asian Journal of Pharmaceutical and Clinical Research","volume":"25 39","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141005489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A CASE REPORT ON STENOTROPHOMONAS MALTOPHILIA","authors":"Vijeta Sharma, Satendra Saraswat, Vijaylaxmi Sharma, Preeti Chauhan","doi":"10.22159/ajpcr.2024.v17i5.49632","DOIUrl":"https://doi.org/10.22159/ajpcr.2024.v17i5.49632","url":null,"abstract":"Stenotrophomonas maltophilia is stated as the Gram-negative bacterium that is often resistant to multiple antibiotics. It is among the most common cause of community-acquired pneumonia in patients with underlying medical conditions, such as diabetes and hypertension. In this case, the patient’s pneumonia did not respond to empiric antibiotic treatment with ceftriaxone and azithromycin. However, his symptoms resolved after treatment with levofloxacin. This case report highlights the importance of considering S. maltophilia in the differential diagnosis of community-acquired pneumonia in patients with underlying medical conditions. Sputum culture with an antibiogram is essential for making the diagnosis and selecting appropriate antibiotic treatment.","PeriodicalId":504156,"journal":{"name":"Asian Journal of Pharmaceutical and Clinical Research","volume":"47 s164","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141002546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"STUDY ON “SURGICAL MANAGEMENT IN DYNAMIC SMALL BOWEL OBSTRUCTION IN ADULT”","authors":"Rekha Patidar, Anil Meena, Manoj Kumar Gupta, Anshul Meena","doi":"10.22159/ajpcr.2024.v17i5.50363","DOIUrl":"https://doi.org/10.22159/ajpcr.2024.v17i5.50363","url":null,"abstract":"Objectives: This study undergoes cases of dynamic small bowel obstruction in the adult population, requiring surgical intervention based on cause, anatomical and pathological nature, age-related factors, mode of presentation, investigation modalities, surgical procedure done, outcome after surgery, and complications.\u0000Methods: The study was conducted on 100 small bowel obstructions from 2020 to 2022. 50 patients in each group requiring surgical intervention based on cause, anatomical, and pathological nature, age-related factors, mode of presentation, investigation modalities, surgical procedure done, and outcome after surgery and complications were analyzed.\u0000Results: In the present study, the most common cause was adhesions and bands followed by hernia. In this study, 56% of the cases belonged to 31–50- year age group; there are 25 males and 25 females. On abdominal examination, diffuse tenderness was present in all 50 cases, followed by (muscle hold) guarding in 35, rigidity in eight, with mass abdomen including seven cases.\u0000Conclusion: Intestinal obstruction is an important surgical emergency, demand vigorous correction of fluid, and electrolyte. Adhesions and bands are the common cause to produce intestinal obstruction. Patients with intestinal obstruction due to adhesions and bands are more likely to develop post-operative complications. Early operation is mandatory to avoid the development of peritonitis and systemic sepsis associated with multi-system organ failure.","PeriodicalId":504156,"journal":{"name":"Asian Journal of Pharmaceutical and Clinical Research","volume":"111 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141003700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"EVALUATION OF ACUTE AND SUB-ACUTE TOXICITY OF METHANOLIC LEAF EXTRACT OF BAMBUSA VULGARIS ON MALE WISTAR RATS","authors":"Susmita Sarkar, Panisree ROY CHOWDHURY, Dipayan Choudhuri","doi":"10.22159/ajpcr.2024.v17i5.50325","DOIUrl":"https://doi.org/10.22159/ajpcr.2024.v17i5.50325","url":null,"abstract":"Objectives: The study aims to evaluate the potential toxicity of methanolic extract of leaves of Bambusa vulgaris in male Wistar rats.\u0000Methods: The methanolic extract was prepared for acute and sub-acute toxicity to determine the lethal dose. During the acute toxicity study, male rats were orally administered with leaf extracts at single doses of 100, 500,800, and 2000 mg/kg according to OECD Guidelines 425 for 14 days. Sub-acute toxicity dose at 200, 400, and 800 mg/kg was studied by daily dosing on male rats for 30 days.\u0000Results: The acute toxicity study revealed no lethal effects and behavioral signs of toxicity at the tested doses indicating that LD50 is <2000 mg/kg. In a sub-acute study, non-significant changes in the body weight (p<0.05), body weight gain percentage (p<0.05) food intake (p<0.05), and relative organ weight percentage (p<0.05), and hematological parameters (p<0.05) of the rats were observed. A significant (p<0.05) increase in ALT level was observed dose at 800 mg/kg. Histopathological analysis showed mild cell distortion in the liver and kidney in male rats treated at 800 mg/kg of extract.\u0000Conclusion: Our study suggests that oral administration of methanolic leaf extract Bambusa vulgais is safe. However, a dose of 800 mg/kg may be toxic for the liver and kidney.","PeriodicalId":504156,"journal":{"name":"Asian Journal of Pharmaceutical and Clinical Research","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141004318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CLINICAL AND LABORATORY PROFILE OF PATIENTS WITH HEPATITIS B INFECTION ATTENDING THE OUTPATIENT DEPARTMENT OF A TERTIARY CARE HOSPITAL IN NORTHEAST INDIA","authors":"Ratan Ram, T. Beyong","doi":"10.22159/ajpcr.2024.v17i5.51129","DOIUrl":"https://doi.org/10.22159/ajpcr.2024.v17i5.51129","url":null,"abstract":"Objective: The objective of this study was to analyze the clinical and laboratory profile of patients with hepatitis B infection-attending outpatient departments of tertiary care hospitals in northeast India.\u0000Methods: This was a cross-sectional study conducted in the outpatient department of a tertiary care medical institute situated in northeast India. Eighty patients infected with hepatitis B (on the basis of serological markers) were included in this study on the basis of predefined inclusion and exclusion criteria. Demographic details such as age, gender, and socioeconomic status of all the patients were noted. A detailed history was taken including any history of intravenous drug use, tattooing, sexual contacts, history of blood transfusions, and familial liver disease. Clinical and laboratory profiles (liver function test and serological markers) of all the patients were studied. Ultrasound imaging was done in all the cases. p<0.05 was taken as statistically significant.\u0000Results: Out of 80 studied cases, there were 49 (61.25%) males and 31 (38.75%) females. The mean age for males and females was 32.30±8.03 and 34.70±13.52 years, respectively. There was no significant difference in mean age between males and females (p=0.3218). Mother-to-child transmission was evenly distributed with 7 males (8.75%) and 9 females (11.25%) affected. Other risk factors, such as dental implants and surgeries, showed a lower prevalence, with dental implants impacting 2 males (2.5%) and 3 females (3.75%) and surgeries concerning 5 males (6.25%) and 3 females (3.75%). Majority of the patients (52.5%) were asymptomatic and were found to be hepatitis B surface antigen (HBsAg) positive incidentally. HBsAg was positive in all cases. 12 (15%) patients showed the presence of hepatitis B e antigen suggestive of high infectivity. Anti-HBc and anti-HBe were positive in 68 (85%) patients each. Hepatomegaly was seen in 23 cases (28.75%) on ultrasound. Moderate fibrosis on elastography was seen in 2 (2.5%) cases.\u0000Conclusion: In cases of hepatitis B, the majority of the patients remained asymptomatic, and many cases no risk factor for hepatitis B virus infection could be identified. It is therefore important to screen the general population for hepatitis B infection.","PeriodicalId":504156,"journal":{"name":"Asian Journal of Pharmaceutical and Clinical Research","volume":"32 S111","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141003643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"EVALUATING THE IMPACT OF HYBRID SIMULATION IN ENHANCING THE LEARNING DOMAINS OF MEDICAL UNDERGRADUATES: A QUASI-EXPERIMENTAL STUDY","authors":"Regina Roy, Indla Ravi, T. C","doi":"10.22159/ajpcr.2024.v17i5.51093","DOIUrl":"https://doi.org/10.22159/ajpcr.2024.v17i5.51093","url":null,"abstract":"Objectivs: Medical education, crucial for understanding physiological processes and clinical application, faces limitations in traditional methods. Simulation-based training addresses this gap, providing a secure environment for hands-on skill practice. The objectives of the study are to (1) evaluate the impact of simulation on enhancing the learning domains of medical undergraduates and (2) gauge students’ perceptions of simulation based medical education (SBME) through a pre-validated, pre-designed questionnaire.\u0000Methods: A quasi-experimental study, involving 60 medical undergraduates, selected by convenient sampling. The study began after obtaining approval from the Institutional Human Ethics Committee and obtaining informed consent from students. A pre-test was conducted for all 60 students followed by a lecture on simulation and then a post-test. The students were then divided into two groups: Group A – SBME using part-task trainers and standardized patients and Group B – (non-SBME) with video lectures on simulation. After 1 month, an assessment of all domains, namely cognitive, affective, and psychomotor, was done by post-test and objective structured clinical examination, respectively. Perception was obtained using the pre-validated questionnaire.\u0000Results: The assessment scores of all domains of Group A (SBME) showed significant improvement p<0.05 except cognitive domain.\u0000Conclusion: SBME is an effective teaching method for improving the learning domains of medical undergraduates.","PeriodicalId":504156,"journal":{"name":"Asian Journal of Pharmaceutical and Clinical Research","volume":"106 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141002306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}