酒精依赖患者家属的抑郁症:观察研究

Piyush Mahajan, Malvika Dahuja
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摘要

研究目的研究旨在了解酒精依赖症患者家属抑郁症的患病率和严重程度:这是一项横断面观察性研究,根据预先确定的纳入和排除标准,按照精神和行为障碍研究诊断标准(ICD-10 DCR)纳入了 50 名酒精依赖患者的家庭成员。酒精依赖的严重程度通过酒精使用障碍鉴定测试-C(AUDIT-C)得分进行评估。通过汉密尔顿抑郁评定量表(HAM-D)评分评估家庭成员中抑郁症的发生率及其严重程度。酒精依赖症患者的 AUDIT-C 评分与家庭成员的 HAM-D 评分之间的相关性采用皮尔逊系数相关统计法进行计算,P<0.05 为有统计学意义:在 50 名酒精依赖症患者中,48 名(96.00%)为男性,2 名(4%)为女性。患者的平均年龄为(41.12±11.02)岁。平均酗酒时间为 8.16±5.39 年。19(38%)名患者的 AUDIT-C 评分为 8 分,而 AUDIT-C 评分为 10 分和 12 分的患者分别有 16(32%)名和 15(30%)名。最常受影响的亲属是配偶(40%),其次是母亲(26%)、兄弟(20%)和父亲(14%)。大多数家庭成员(82%)患有轻度抑郁症(评分介于 8 至 13 分之间)。九名患者(18%)没有任何抑郁症。没有任何家庭成员患有中度、重度或极重度抑郁症。酒精依赖症患者的 AUDIT-C 评分与家庭成员的 HAM-D 评分之间存在明显的正相关性(R 评分=0.6333,P<0.005):结论:酒精依赖对家庭成员的心理影响很大,尤其是抑郁。危险饮酒的严重程度与家庭成员抑郁的发生率呈正相关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
DEPRESSION IN FAMILY MEMBERS OF ALCOHOL DEPENDENCE PATIENTS: AN OBSERVATIONAL STUDY
Objectives: The aim of the study was to find out prevalence and severity of depression in family members of alcohol-dependence patients. Methods: This was a cross-sectional, observational study in which 50 family members of patients with alcohol dependence according to mental and behavioral disorders diagnostic criterion for research (ICD-10 DCR) included on the basis of a predefined inclusion and exclusion criteria. The severity of alcohol dependence was assessed by Alcohol Use Disorders Identification Test-C (AUDIT-C) score. The incidence of depression and its severity in family members was assessed by Hamilton Rating Scale for Depression (HAM-D) score. The correlation of AUDIT-C score in alcohol-dependent patients and HAM-D score in family members was done by using Pearson coefficient correlation statistical purposes p<0.05 was considered as statistically significant. Results: Out of the 50 patients with alcohol dependence, 48 (96.00%) were males and 2 (4%) were females. The mean age of the patients was found to be 41.12±11.02. The mean duration of alcoholism was 8.16±5.39 years. 19 (38%) patients had AUDIT-C score of 8 whereas AUDIT-C score of 10 and 12 was found in 16 (32%) and 15 (30%) patients each. The most commonly affected relative was spouse (40%), followed by mother (26%), brother (20%), and father (14%). Majority of the family members (82%) had mild depression (score between 8 and 13). Nine (18%) patients did not have any depression. Moderate, severe, or very severe depression was not seen in any family member. There was a significant positive correlation between AUDIT-C score in alcohol-dependent patients and HAM-D score in family members (R score=0.6333 and p<0.005). Conclusion: There is a significant psychological impact, particularly depression, of alcohol dependence on family members. Severity of hazardous drinking correlated positively with the incidence of depression in family members.
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