International Journal of Psychiatry in Medicine最新文献_第5页

Effectiveness of cognitive behavioral therapy in relieving tinnitus. 评估认知行为疗法对耳鸣的疗效。

IF 1.1 4区医学

International Journal of Psychiatry in Medicine Pub Date : 2025-07-01 Epub Date: 2024-08-17 DOI: 10.1177/00912174241272674

Fatih Bal

{"title":"Effectiveness of cognitive behavioral therapy in relieving tinnitus.","authors":"Fatih Bal","doi":"10.1177/00912174241272674","DOIUrl":"10.1177/00912174241272674","url":null,"abstract":"ObjectiveThis study examined the effects of Cognitive Behavioral Therapy (CBT) on tinnitus in individuals aged 18-60 years.MethodsThirty participants with subjective tinnitus for at least six months were included in a randomized controlled trial. Randomized were 15 participants in the experimental group and 15 in the control group, with pre-test and post-test measurements. The experimental group received eight CBT sessions over eight weeks. Data were collected using Tinnitus Handicap Inventory (THI) and Visual Analog Scale (VAS). The Mann-Whitney and Wilcoxon Signed Rank Test were used to compare scores between experimental and control groups at baseline and after the intervention.ResultsA within-group difference was found between total scores on THI and VAS before and after CBT in the experimental (z = -3.241, P = 0.001), but not in the control group (z = -1.764, P = 0.078). Following the intervention, there was a significant between-group difference on the THI Emotional, Catastrophic, and Functional tinnitus subscale scores, favoring the experimental group.ConclusionsCBT significantly reduced tinnitus level, severity, duration, frequency, discomfort, tinnitus-related attention deficit, and sleep problems. Further studies are needed to replicate these findings in larger samples and other populations.","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":" ","pages":"420-442"},"PeriodicalIF":1.1,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141996809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diagnostic awareness, psychosocial symptoms, and survival time in patients with advanced lung cancer. 晚期肺癌患者的诊断意识与社会心理症状和生存时间的关系。

IF 1.1 4区医学

International Journal of Psychiatry in Medicine Pub Date : 2025-07-01 Epub Date: 2024-10-14 DOI: 10.1177/00912174241291714

Hulya Abali, Seda Tural Onur, Yusuf Baser, Dilara Demir, Asli Bicen

{"title":"Diagnostic awareness, psychosocial symptoms, and survival time in patients with advanced lung cancer.","authors":"Hulya Abali, Seda Tural Onur, Yusuf Baser, Dilara Demir, Asli Bicen","doi":"10.1177/00912174241291714","DOIUrl":"10.1177/00912174241291714","url":null,"abstract":"ObjectiveDisclosing to patients the diagnosis of lung cancer is an issue, especially in the Middle East where cultural factors may prohibit disclosure from being done. The psychosocial consequences of diagnostic awareness and its impact on life expectancy is an important issue that may influence the disclosure decision. The present study evaluated the effects of diagnostic awareness on psychosocial symptomatology and survival time in patients with advanced lung cancer in Turkey.MethodsThis prospective cohort study included 126 advanced lung cancer patients admitted to the oncology department between February 2021 and August 2021. A face-to-face survey included questions on age, gender, marital/employment statuses, comorbidities, and psychological symptoms (SCL-90-R). Diagnostic awareness was assessed by asking patients whether they knew their diagnosis. The correlation of diagnostic awareness with 2-year survival time was analyzed using Cox regression analysis.ResultsOf the 126 patients, had 86 died at the time of follow-up. Survival time and scores on SCL-90-R symptom subscales were compared between diagnosis-aware (79.4%) and diagnosis-unaware groups (20.6%). Somatization (P = 0.04), depression (P = 0.01), hostility (P = 0.03), scores on additional symptom scales (P = 0.01), and symptom total scores (P = 0.01) were significantly higher in the diagnosis-unaware group. No significant difference was found between diagnostic awareness and survival time (P = 0.24).ConclusionsAdvanced lung cancer patients aware of their diagnosis experienced less psychosocial burden. However, no significant difference was found in survival time between diagnosis-aware and diagnosis-unaware patients. These findings suggest that the diagnosis should be disclosed to lung cancer patients after confirmation.","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":" ","pages":"456-467"},"PeriodicalIF":1.1,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142479627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Psychotropic medication and hepatobiliary health: Ultrasound observations on patients with schizophrenia. 精神药物与肝胆健康：对精神分裂症患者的超声波观察。

IF 1.1 4区医学

International Journal of Psychiatry in Medicine Pub Date : 2025-07-01 Epub Date: 2024-09-05 DOI: 10.1177/00912174241280510

Linlin Yue, Linlin Sun, Nan Li

{"title":"Psychotropic medication and hepatobiliary health: Ultrasound observations on patients with schizophrenia.","authors":"Linlin Yue, Linlin Sun, Nan Li","doi":"10.1177/00912174241280510","DOIUrl":"10.1177/00912174241280510","url":null,"abstract":"ObjectiveThis study sought to examine the association between antipsychotic drug use and hepatobiliary health based on serum markers and ultrasound observations on a sample of patients with schizophrenia compared to age and gender matched healthy controls.MethodsThe 120 patients with schizophrenia and 60 control subjects had their blood drawn to measure liver function tests and underwent hepatobiliary ultrasonography to determine hepatobiliary lesions. Liver function tests included total cholesterol (TC), triglycerides (TG), alanine aminotransferase (ALT), and aspartate aminotransferase (AST). Standardized cross-sectional images of the liver and kidneys were obtained from patients and controls, and analyses were stratified by length of taking psychotropic medication among those with schizophrenia. Liver echo attenuation coefficients, liver-kidney ratios, and liver fat content were determined.ResultsPsychotropic drug use was associated with greater liver burden and liver lesions in patients with schizophrenia compared to controls. The levels of TC, TG, ALT and AST in patients with schizophrenia were all significantly higher among patients with schizophrenia. Long-term psychotropic medication was associated with increased levels of fatty liver in patients compared with controls. Levels of TC, TG, ALT and AST were significantly higher in the long-term psychotropic medication use group than in the short-term group. Liver echo attenuation coefficient, liver-kidney ratio, and liver fat content were also higher in the long-term medication use group compared to the short-term group.ConclusionAntipsychotic drug use, particularly long-term use, is associated with increased liver burden in patients with schizophrenia, impaired lipid metabolism, increased liver lesions and fat content.","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":" ","pages":"395-404"},"PeriodicalIF":1.1,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142134322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nutritional intake and adequacy of intake among Vietnamese outpatients with major depressive disorder: A 24-hour recall study. 越南重度抑郁症门诊患者的营养摄入和摄入充足性：一项24小时回顾研究。

IF 1.1 4区医学

International Journal of Psychiatry in Medicine Pub Date : 2025-06-18 DOI: 10.1177/00912174251352405

Manh Xuan Bui, Linh Tich Ngo, Phuc Truong Vinh Le, Phong Duy Nguyen

{"title":"Nutritional intake and adequacy of intake among Vietnamese outpatients with major depressive disorder: A 24-hour recall study.","authors":"Manh Xuan Bui, Linh Tich Ngo, Phuc Truong Vinh Le, Phong Duy Nguyen","doi":"10.1177/00912174251352405","DOIUrl":"https://doi.org/10.1177/00912174251352405","url":null,"abstract":"ObjectiveThis study assessed the 24-h nutrient intake, adequacy of intake, and associated factors among outpatients diagnosed with major depressive disorder (MDD) in Ho Chi Minh City, Vietnam.MethodA cross-sectional study was conducted among 290 adult outpatients diagnosed with MDD at University Medical Center, Ho Chi Minh City, Vietnam. Participants completed a 24-h dietary recall and the Quick Inventory of Depressive Symptomatology (QIDS-SR). Nutrient intake was analyzed using Vietnamese food composition tables and categorized based on national dietary recommendations. Mean daily nutrient intakes were calculated for energy, macronutrients, and micronutrients. Multivariate analyses assessed associations between demographic, clinical, and psychosocial factors and nutrient intake.ResultsParticipants demonstrated low average intake of energy, macronutrients, and essential micronutrients. A majority had inadequate intake of total energy, carbohydrates, fats, and key vitamins and minerals such as calcium, potassium, and vitamins A and C. Nutritional deficiencies were more pronounced among individuals with greater depression severity, limited time for self-care, underweight status, and fewer economic resources. Principal component analysis revealed two main dietary patterns: one nutrient-rich and another characterized by high fat and sodium with low vitamin content.ConclusionsIndividuals with MDD in Vietnam demonstrate widespread inadequacy of nutrient intake, which was associated with both depression severity and several sociodemographic factors. These findings underscore the importance of integrating nutrition assessment and intervention into mental health care in the country of Vietnam and likely elsewhere.","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":" ","pages":"912174251352405"},"PeriodicalIF":1.1,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144327630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prevalence rates of depression, anxiety, and suicidal ideation in patients with ovarian cancer: A systematic review from 1977 to 2024. 卵巢癌患者抑郁、焦虑和自杀意念的患病率：1977年至2024年的系统回顾

IF 1.1 4区医学

International Journal of Psychiatry in Medicine Pub Date : 2025-06-13 DOI: 10.1177/00912174251350465

Tong Qiu, Tian Zhang, YiHan Zhang, XingKe Qiu

{"title":"Prevalence rates of depression, anxiety, and suicidal ideation in patients with ovarian cancer: A systematic review from 1977 to 2024.","authors":"Tong Qiu, Tian Zhang, YiHan Zhang, XingKe Qiu","doi":"10.1177/00912174251350465","DOIUrl":"https://doi.org/10.1177/00912174251350465","url":null,"abstract":"ObjectiveOvarian cancer patients are more likely to have mental disorders than other patients. However, to our knowledge, there has been no systematic analysis of its global epidemiology. Therefore, a systematic review was conducted to identify the prevalence of depression, anxiety, and suicidal ideation in ovarian cancer patients in different countries.MethodWe searched PubMed, Embase, Elsevier ScienceDirect, China National Knowledge Infrastructure, WanFang Data Knowledge Service Platform, and Duxiu Academic Search Platform to identify observational studies on depression, anxiety, and suicidal ideation in patients with ovarian cancer published up to 30 June 2024. We estimated the prevalence of depression, anxiety, and suicidal ideation in ovarian cancer patients worldwide and by region, country, research period, and assessment scales.ResultsA total of 31 studies were identified involving 8315 ovarian cancer patients. The prevalence rates of depression and anxiety were 35% and 37%, respectively. In China, the prevalence of suicidal ideation of ovarian cancer patients was 32%. Ovarian cancer patients in Asia had the highest prevalence of depression, while those in Oceania (Australia, New Zealand, etc.) had the lowest. Additionally, the prevalence rates of depression and anxiety increased considerably worldwide after 2000 and have gradually stabilized since then.ConclusionThis study found that the prevalence of depression and anxiety was high (more than one-third) among ovarian cancer patients. These findings underscore the need for a comprehensive study to address mental health problems in these patients, including the determination of incidence rates, investigation of regional differences, and assessment of comorbidities and treatment strategies.","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":" ","pages":"912174251350465"},"PeriodicalIF":1.1,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144295181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cross-disciplinary cardiovascular and psychiatric recommendations: A systematic review of clinical guidelines. 跨学科心血管和精神病学建议：临床指南的系统回顾。

IF 1.1 4区医学

International Journal of Psychiatry in Medicine Pub Date : 2025-06-12 DOI: 10.1177/00912174251348996

Marina Delli Colli, Kyle T Greenway, Michael Goldfarb

{"title":"Cross-disciplinary cardiovascular and psychiatric recommendations: A systematic review of clinical guidelines.","authors":"Marina Delli Colli, Kyle T Greenway, Michael Goldfarb","doi":"10.1177/00912174251348996","DOIUrl":"https://doi.org/10.1177/00912174251348996","url":null,"abstract":"IntroductionIndividuals with serious mental illness (SMI), including major depression, schizophrenia, and bipolar disorder, experience disproportionately high rates of cardiovascular (CV) risk and disease. Despite this well-established connection, it remains unclear how professional society guidelines across cardiology and psychiatry address this relationship.MethodsMajor American and European CV and psychiatric society guidelines published from 2013-2023 were reviewed. Included were guidelines on primary and secondary CV disease prevention, and disease-specific guidelines for schizophrenia, bipolar disorder, and major depressive disorder. Relevant text was extracted and classified as recommendations or supporting text.ResultsTwenty-six guidelines were included (13 CV; 13 psychiatric). Psychiatric considerations appeared in 5 CV guidelines (38%), most commonly addressing mental illness treatment to improve CV outcomes (n = 5), pharmacological considerations (n = 2), and recognition of mental illness as a CV risk factor (n = 2). Only 13% of American CV guidelines included psychiatric content, compared to 80% of European CV guidelines. In contrast, 10 psychiatric guidelines (77%) included CV-related recommendations, including CV screening (n = 16), pharmacological considerations (n = 8), and risk factor control (n = 7). Among psychiatric guidelines, 40% of U.S. and 100% of European documents included CV content.ConclusionsCV considerations are more frequently addressed in psychiatric than psychiatric considerations in CV guidelines. European guidelines showed greater cross-disciplinary integration. These findings highlight the need for more unified, interdisciplinary guidance to reduce CV risk in individuals with SMI.","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":" ","pages":"912174251348996"},"PeriodicalIF":1.1,"publicationDate":"2025-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144287005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Risk of metabolic syndrome in patients with bipolar disorder in Türkiye: A one-year follow-up study. <s:1> rkiye双相情感障碍患者代谢综合征的风险：一年随访研究。

IF 1.1 4区医学

International Journal of Psychiatry in Medicine Pub Date : 2025-06-10 DOI: 10.1177/00912174251350817

Rukiye Tekdemir, Fatih Ekici, Hasan Ali Güler, Muhammet Tuğrul Ergün, Yavuz Selvi

{"title":"Risk of metabolic syndrome in patients with bipolar disorder in Türkiye: A one-year follow-up study.","authors":"Rukiye Tekdemir, Fatih Ekici, Hasan Ali Güler, Muhammet Tuğrul Ergün, Yavuz Selvi","doi":"10.1177/00912174251350817","DOIUrl":"https://doi.org/10.1177/00912174251350817","url":null,"abstract":"ObjectiveThis study examined the incidence of metabolic syndrome (MetS) in 100 individuals with bipolar disorder (BD) and identified clinical and biological predictors of incident MetS during a 1-year follow-up.MethodsThe study included euthymic BD type-1 patients consecutively recruited from outpatient clinics between July 2023 and July 2024. MetS was defined according to International Diabetes Federation criteria. Patients without MetS at baseline but with MetS during follow-up were classified as having incident MetS. A logistic regression model was utilized to estimate the adjusted odds ratios (OR) and corresponding 95% confidence intervals (CIs) for associations between predictors and incident MetS.ResultsOf the 100 participants enrolled in the study (92% response rate), 29% met MetS criteria at baseline. Of the 71 without baseline MetS, 29 (40.8%) developed MetS over a 1-year period. Significant predictors of MetS onset included a higher number of manic/hypomanic episodes (OR = 1.459, 95% CI = 1.005-2.118, P = .047), increased chlorpromazine-equivalent antipsychotic dosages (OR = 1.007, 95% CI = 1.001-1.013, P = .024), high waist circumference (OR = 1.247, 95% CI = 1.052-1.479, P = .011), and hypertriglyceridemia (OR = 1.041, 95% CI = 1.007-1.077, P = .020). Conversely, lamotrigine use was inversely associated with MetS development (OR = 0.030, 95% CI = 0.001-0.659, P = .026).ConclusionA high incidence of MetS (41%) was observed within 1 year among patients with BD. Identified risk factors highlight opportunities for intervention through mood recurrence prevention, careful pharmacotherapy management, and treatment of pre-existing components of MetS.","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":" ","pages":"912174251350817"},"PeriodicalIF":1.1,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144267786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Perceptions and attitudes of mental healthcare providers regarding unconventional causes and treatments for psychiatric disorders in Saudi Arabia. 沙特阿拉伯精神卫生保健提供者对精神疾病的非常规原因和治疗的看法和态度。

IF 1.1 4区医学

International Journal of Psychiatry in Medicine Pub Date : 2025-06-05 DOI: 10.1177/00912174251350472

Deemah Ateeq Alateeq, Hussain Altaweel, Sumayah Aljhani, Faten Al Eid, Ebtesam Almajed, Asma Alshammari

{"title":"Perceptions and attitudes of mental healthcare providers regarding unconventional causes and treatments for psychiatric disorders in Saudi Arabia.","authors":"Deemah Ateeq Alateeq, Hussain Altaweel, Sumayah Aljhani, Faten Al Eid, Ebtesam Almajed, Asma Alshammari","doi":"10.1177/00912174251350472","DOIUrl":"https://doi.org/10.1177/00912174251350472","url":null,"abstract":"ObjectiveThe stigmatization of mental illnesses remains an obstacle to seeking help and proper treatment. This study explored the knowledge and attitudes of mental health providers (MHPs) toward unconventional causes and treatments for psychiatric disorders in Saudi Arabia.MethodsA descriptive cross-sectional study was conducted between July and December 2020 with MHPs working in the governmental and private sectors, including general and mental health hospitals and centers across Saudi Arabia. The questionnaire assessed sociodemographic characteristics, attitudes toward patients with psychiatric disorders, and perceptions of causes and treatments for psychiatric disorders.ResultsIn total, 449 MHPs completed the questionnaire. More than half (51.7%) believed that supernatural causes could contribute to mental illness. In terms of treatment, most MHPs believed cauterization (81.1%), drinking occasionally (78.8%), cupping therapy (74.2%), amphetamine or hash (63.5%), and headbands (51%) were helpful. Reluctance to marry a person previously diagnosed with mental illness is the most widely agreed upon attitude toward mental illness. Multivariate analysis indicated that psychiatrists and psychologists (29% of MHPs) were the least likely to believe in supernatural causes compared to other MHPs (P < 0.001).ConclusionThe findings of this study highlight the need for awareness and education about MHPs regarding scientific causes and proven treatments for mental illnesses. Evidence-based information is essential to dispel misconceptions regarding mental health problems. Doing so may help reduce the stigma and discrimination faced by those suffering from mental illnesses, thereby supporting their recovery.","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":" ","pages":"912174251350472"},"PeriodicalIF":1.1,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144235796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Factors associated with antidepressant use following hospitalization for acute stroke. 急性脑卒中住院后抗抑郁药物使用的相关因素

IF 1.1 4区医学

International Journal of Psychiatry in Medicine Pub Date : 2025-06-03 DOI: 10.1177/00912174251348329

Hely D Nanavati, Nicole C Wright, Melissa J Smith, Shakia T Hardy, Virginia J Howard, Chen Lin

{"title":"Factors associated with antidepressant use following hospitalization for acute stroke.","authors":"Hely D Nanavati, Nicole C Wright, Melissa J Smith, Shakia T Hardy, Virginia J Howard, Chen Lin","doi":"10.1177/00912174251348329","DOIUrl":"10.1177/00912174251348329","url":null,"abstract":"ObjectiveDepression is the most common mental health complication after stroke, leading to poor post-stroke outcomes. Few observational studies have reported factors associated with antidepressant use in these patients. Therefore, this study assessed patient and clinical characteristics associated with receiving antidepressant prescriptions at discharge following hospital admission for acute stroke.MethodsIdentified were patients admitted with acute stroke or transient ischemic attack from the institutional stroke registry (October 1, 2019, through October 31, 2020). Electronic health record review was used to assess antidepressant prescription at discharge and predictors such as demographics, health behaviors, clinical comorbidities, and stroke prognostic characteristics.ResultsOut of 803 patients with stroke, 220 (27.4%) received an antidepressant prescription at discharge, including 82 (12.8%) patients who were started on antidepressants at discharge. A multivariable model indicated that sex (female vs male OR = 1.53; 95% CI = 1.09, 2.16), race (Black vs White: OR = 0.67; 95% CI = 0.47, 0.96), number of clinical comorbidities (OR = 1.16; 95% CI = 1.03, 1.32), history of depression (OR = 4.91; 95% CI = 2.59, 9.31), and discharge disposition (to inpatient rehabilitation facility vs home: OR = 1.52; 95% CI = 1.01, 2.30) were significantly associated with receipt of antidepressant prescriptions among all users. Discharge disposition (to an inpatient rehabilitation facility) was the only variable associated with initiating an antidepressant prescription at discharge (OR = 2.92; 95% CI = 1.62, 5.28).ConclusionAntidepressant prescriptions for poststroke patients were more frequent among females, White adults, and those discharged to an inpatient rehabilitation facility. These findings describing antidepressant prescription patterns underscore the need for specific guidelines aiding antidepressant use after stroke.","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":" ","pages":"912174251348329"},"PeriodicalIF":1.1,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144217432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Brain-derived neurotrophic factor as predictor of early-onset poststroke depression. 脑源性神经营养因子作为早发性脑卒中后抑郁的预测因子。

IF 1.1 4区医学

International Journal of Psychiatry in Medicine Pub Date : 2025-05-28 DOI: 10.1177/00912174251347410

Emine Yıldırım Uslu, Sevler Yildiz, Sevda Korkmaz

{"title":"Brain-derived neurotrophic factor as predictor of early-onset poststroke depression.","authors":"Emine Yıldırım Uslu, Sevler Yildiz, Sevda Korkmaz","doi":"10.1177/00912174251347410","DOIUrl":"https://doi.org/10.1177/00912174251347410","url":null,"abstract":"BackgroundPoststroke depression (PSD) with an approximately one third prevalence in stroke patients is associated with increased morbidity and mortality. This study aimed to investigate the potential relationship between brain-derived neurotrophic factor (BDNF) levels in serum and early-onset PSD as well as clinical variables.MethodsClinical data and radiological images of 88 patients diagnosed with acute ischemic stroke were examined. Serum BDNF levels were measured within the first 72 hours following stroke diagnosis. On the 14th day following stroke diagnosis, Montreal Cognitive Assessment (MoCA), Hamilton Depression Rating Scale (HAM-D17), and National Institutes of Health Stroke Scale (NIHSS) were applied to the patients.ResultsSerum BDNF levels (P = 0.022) and MoCA values (P = 0.004) of patients with early-onset PSD were significantly lower, and NIHSS values (P = 0.027) were significantly higher compared to patients without early-onset PSD. There was a significantly negative correlation between BDNF value and HAMD-17 score and lymphocytes. Receiver operating characteristic (ROC) analysis was used to investigate the extent the BDNF level could predict the occurrence of early-onset PSD and cut-off values were determined. For a BDNF cut-off value of 361.51, sensitivity and specificity values were 75% and 56.2%, respectively, which indicated that BDNF may be a useful indicator associated with early-onset PSD.ConclusionLower serum BDNF levels are associated with early-onset PSD and may serve as a potential biomarker, although causal or predictive conclusions are limited due to the study's cross-sectional design.","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":" ","pages":"912174251347410"},"PeriodicalIF":1.1,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144163679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0