International Journal of Psychiatry in Medicine最新文献_第10页

Dietary total antioxidant capacity and serum 8-OHdG in patients with schizophrenia. 精神分裂症患者的膳食总抗氧化能力和血清8-OHdG。

IF 2 4区医学

International Journal of Psychiatry in Medicine Pub Date : 2023-11-01 Epub Date: 2023-05-21 DOI: 10.1177/00912174231177638

Gülbin Karagöl, Emrah Songur, Neslişah Rakıcıoğlu

{"title":"Dietary total antioxidant capacity and serum 8-OHdG in patients with schizophrenia.","authors":"Gülbin Karagöl, Emrah Songur, Neslişah Rakıcıoğlu","doi":"10.1177/00912174231177638","DOIUrl":"10.1177/00912174231177638","url":null,"abstract":"Background: Dietary total antioxidant capacity serves as an indicator for dietary quality and reflects daily antioxidant intake. This study aimed to determine the oxidative stress status of patients with schizophrenia and to examine the relationship between dietary total antioxidant capacity (dTAC) and 8-hydroxy-2'-deoxyguanosine (8-OHdG), a marker for oxidative stress.Methods: This study was conducted in Turkey and involved 40 patients diagnosed with schizophrenia or schizoaffective disorder according to the Diagnostic and Statistical Manual of Mental Disorders, 5th ed., and 30 healthy controls matched for age and gender. The participants' sociodemographic characteristics and nutritional habits were determined through face-to-face interviews and through the use of questionnaires. The dTAC and dietary oxidative balance scores were calculated using a three-day dietary intake record. 8-OHdG levels were analyzed in the serum samples collected from the subjects.Results: Dietary ferric reducing antioxidant power (FRAP-1, FRAP-2), Trolox equivalence antioxidant capacity (TEAC), and oxygen radical absorbance capacity (H-ORAC) values were lower in patients with schizophrenia than in the healthy controls (P < 0.05). Serum 8-OHdG levels were found similar in both groups (P > 0.05).Conclusion: Nutritional interventions are needed in patients with schizophrenia given that insufficient antioxidant intake may increase oxidative stress, which in turn affects disease development. Therefore, healthy nutrition, especially sufficient intake of dietary antioxidants, should be encouraged in patients with schizophrenia.","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9490651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Insights on the treatment of anorexia nervosa, dietary factors in serious mental disorder, adverse childhood experiences and medication allergy, migraine in bipolar disorder and schizophrenia, spirituality and glycemic control in type II diabetes, and assessing burnout in primary care. 对神经性厌食症的治疗、严重精神障碍的饮食因素、不良童年经历和药物过敏、双相情感障碍和精神分裂症的偏头痛、II型糖尿病的精神和血糖控制的见解，以及对初级保健倦怠的评估。

IF 2 4区医学

International Journal of Psychiatry in Medicine Pub Date : 2023-11-01 Epub Date: 2023-09-22 DOI: 10.1177/00912174231205456

Harold G Koenig

引用次数: 0

Internalizing disorders as a mediator of the association between adverse childhood experiences and perceived medication intolerance or poly-allergy. 将疾病内化为儿童不良经历与感知的药物不耐受或多发性过敏之间联系的中介。

IF 2 4区医学

International Journal of Psychiatry in Medicine Pub Date : 2023-11-01 Epub Date: 2023-05-11 DOI: 10.1177/00912174231175742

Carissa van den Berk-Clark, Abigail Grant, Megan Ferber

{"title":"Internalizing disorders as a mediator of the association between adverse childhood experiences and perceived medication intolerance or poly-allergy.","authors":"Carissa van den Berk-Clark, Abigail Grant, Megan Ferber","doi":"10.1177/00912174231175742","DOIUrl":"10.1177/00912174231175742","url":null,"abstract":"Objectives: There is a well-established link between adverse childhood events, mental health, and physical health conditions. There is also a large literature showing the relationship between medication intolerance or allergies, and poor health outcomes. However, less is understood about the role of medication intolerance and adverse childhood events. Thus, the present study examines the relationship between adverse childhood events, internalizing disorders (depression, anxiety) and medication intolerance.Method: Three hundred forty-nine participants were recruited from 11 primary care practices and health networks located in a large, Midwestern metropolitan area. Unrelated linear and Poisson regression was used to determine whether internalizing disorders, such as depression and anxiety, mediated the relationship between adverse childhood experiences (ACEs) and allergies to medications, accounting for error terms in regression equations that were correlated.Results: Results indicated an association between ACEs and number of allergies to medication, whereby ACEs was associated with depression, anxiety and number of allergies. Sensitivity analysis confirmed these findings. There was a small but significant indirect effect of anxiety on allergies to medication after bootstrapping.Conclusion: This study found that inflammatory responses occurring because of trauma and depression may be increasing medication allergies. However, given the size of the sample, more research is needed to confirm these results. Implications for healthcare providers are discussed.","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9799377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prevalence and correlates of child maltreatment among mothers in the Kurdistan province, Western Iran. 伊朗西部库尔德斯坦省母亲虐待儿童的患病率及其相关因素。

IF 2 4区医学

International Journal of Psychiatry in Medicine Pub Date : 2023-09-01 DOI: 10.1177/00912174231163740

Sahel Khazaei, Alireza Salehi, Hossein Molavi Vardanjani

{"title":"Prevalence and correlates of child maltreatment among mothers in the Kurdistan province, Western Iran.","authors":"Sahel Khazaei, Alireza Salehi, Hossein Molavi Vardanjani","doi":"10.1177/00912174231163740","DOIUrl":"https://doi.org/10.1177/00912174231163740","url":null,"abstract":"Objective: Parental child maltreatment is a serious public health issue worldwide. As mothers take on a significant proportion of parenting duties in two-parent families, knowledge of maternal risk factors for child maltreatment is essential.Methods: In this cross-sectional study, 135 mothers with their last child under 18 years in Kurdistan province were enrolled. A validated Persian version of the ISPCAN Child Abuse Screening Tool-Parent version, Beck Anxiety Inventory, and Beck Depression Inventory were administered.Results: The prevalence of severe and moderate physical punishment was 78.5% and 71.9%, respectively. Psychological punishment was reported by 99.3% of respondents, and 48.9% reported neglect. A relationship was found between child physical and emotional abuse and low maternal education (p < 0.01), domestic violence (p = 0.02), maternal exposure to maltreatment during childhood (p = 0.03), maternal depression (p < 0.01), and maternal anxiety (p < 0.01). A relationship was also found between child neglect and residence in rural areas (p < 0.01), domestic violence, and low maternal education (p = 0.02).Conclusion: Maternal child maltreatment in Iran is increased in mothers with psychological disorders and those with certain demographic characteristics. Clinicians should be alert to these potential risk factors.","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9926645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Chronic use of benzodiazepines: The problem that persists. 长期使用苯二氮卓类药物:持续存在的问题。

IF 2 4区医学

International Journal of Psychiatry in Medicine Pub Date : 2023-09-01 DOI: 10.1177/00912174231166252

Dexter L Louie, Oluwole O Jegede, Gretchen L Hermes

引用次数: 0

Association of CTNND2 gene polymorphism with schizophrenia: Two-sample case-control study in Chinese Han population. CTNND2基因多态性与精神分裂症的关系:中国汉族人群的两样本病例对照研究

IF 2 4区医学

International Journal of Psychiatry in Medicine Pub Date : 2023-09-01 DOI: 10.1177/00912174231164669

Zhaonian Chen, Xiaojing Li, Xiangzheng Cui, Luwen Zhang, Qing Liu, Yanli Lu, Xiujuan Wang, Han Shi, Minli Ding, Yongfeng Yang, Wenqiang Li, Luxian Lv

{"title":"Association of CTNND2 gene polymorphism with schizophrenia: Two-sample case-control study in Chinese Han population.","authors":"Zhaonian Chen, Xiaojing Li, Xiangzheng Cui, Luwen Zhang, Qing Liu, Yanli Lu, Xiujuan Wang, Han Shi, Minli Ding, Yongfeng Yang, Wenqiang Li, Luxian Lv","doi":"10.1177/00912174231164669","DOIUrl":"https://doi.org/10.1177/00912174231164669","url":null,"abstract":"Objectives: Genetic factors play an important role in the etiology of schizophrenia (SZ). Catenin Delta 2 (CTNND2) is one of the genes regulating neuronal development in the brain. It is unclear whether CTNND2 is involved in SZ. With the hypothesis that CTNND2 may be a risk gene for SZ, we performed a case-control association analysis to investigate if CTNND2 gene single nucleotide polymorphisms (SNPs) are implicated in SZ in a Han Chinese population.Materials and methods: We recruited subjects from 2010 to 2022 from the Han population of northern Henan and divided them into two case-control samples, including a discovery sample (SZ = 528 and controls = 528) and replication sample (SZ = 2458 and controls = 6914). Twenty-one SNPs were genotyped on the Illumina BeadStation 500G platform using GoldenGate technology and analyzed by PLINK. The Positive and Negative Syndrome Scale (PANSS) was used to assess clinical symptoms.Results: Rs16901943, rs7733427, and rs2168878 SNPs were associated with SZ (Chi2 = 7.484, 11.576, and 5.391, respectively, df = 1; p = 0.006, 0.00067, and 0.02, respectively) in the two samples. Rs10058868 was associated with SZ in male patients in the discovery sample (Chi2 = 6.264, df = 1, p = .044). Only the relationship with rs7733427 survived Bonferroni correction. Linkage disequilibrium block three haplotypes were associated with SZ in the discovery and total sample. PANSS analysis of the four SNPs implicated rs10058868 and rs2168878 in symptoms of depression and excitement, respectively, in the patients with SZ.Conclusion: Four SNPs of the CTNND2 gene were identified as being correlated with SZ. This gene may be involved in susceptibility to SZ.","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9920872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of COVID-19 anxiety and obsession on fear of childbirth in high-risk pregnancy during the pandemic in Turkey. 2019冠状病毒病焦虑和痴迷对土耳其大流行期间高危妊娠患者分娩恐惧的影响

IF 2 4区医学

International Journal of Psychiatry in Medicine Pub Date : 2023-09-01 DOI: 10.1177/00912174231183925

Sena D Aksoy, Suzi Ozdemir, Esra Akbal

{"title":"Effects of COVID-19 anxiety and obsession on fear of childbirth in high-risk pregnancy during the pandemic in Turkey.","authors":"Sena D Aksoy, Suzi Ozdemir, Esra Akbal","doi":"10.1177/00912174231183925","DOIUrl":"https://doi.org/10.1177/00912174231183925","url":null,"abstract":"Objective: The COVID-19 pandemic may have significant effects on fear of childbirth among women undergoing a high-risk pregnancy. This study sought to determine the relationship between the COVID-19 obsession and anxiety levels of women with high-risk pregnancies and their fear of childbirth.Methods: A total of 326 hospitalized women with high-risk pregnancies were evaluated between March 2021 and March 2022. The COVID-19 Anxiety Scale (CAS), COVID-19 Obsession Scale (OCS), and Fear of Birth Scale (FOBS, composed of two subscales, FOBS1-anxiety and FOBS2-fear) were administered.Results: Positive correlations were found between the FOBS1 and FOBS2 scores and CAS and OCS total scores (p < .001). The participants with secondary school degrees, those who had not given birth before, those who had an unfavorable previous childbirth experience, and those who were planning to have vaginal delivery had significantly higher average FOBS1 and FOBS2 scores (p < .05). Those living in an extended family were 3.22 times more likely to experience FOBS1 and 2.23 times more likely to experience FOBS2 than those living in a nuclear family. Women following COVID-19 information were 3.69 times more likely than others to experience these symptoms. In addition, those scheduled for vaginal delivery were 1.80 times more likely to experience FOBS2 than those scheduled for caesarean section.Conclusion: Women with high-risk pregnancies may experience COVID-19 anxiety, which may worsen their fear of childbirth. Psychosocial interventions focused on addressing COVID-19 anxiety are warranted for women with high-risk pregnancies in Turkey and for those living in other areas of the world as well.","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10273047/pdf/10.1177_00912174231183925.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9927656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correlates of poor clinical outcomes related to COVID-19 among older people with psychiatric illness - a mixed methods study. 老年精神疾病患者与COVID-19相关的不良临床结果的相关性——一项混合方法研究

IF 2 4区医学

International Journal of Psychiatry in Medicine Pub Date : 2023-09-01 DOI: 10.1177/00912174231171220

Surajudeen Abdulrahman, Naser Al-Balushi, Jason Holdcroft-Long, Uzma Khan, Bipin Ravindran, Sujata Das, Anto P Rajkumar

{"title":"Correlates of poor clinical outcomes related to COVID-19 among older people with psychiatric illness - a mixed methods study.","authors":"Surajudeen Abdulrahman, Naser Al-Balushi, Jason Holdcroft-Long, Uzma Khan, Bipin Ravindran, Sujata Das, Anto P Rajkumar","doi":"10.1177/00912174231171220","DOIUrl":"https://doi.org/10.1177/00912174231171220","url":null,"abstract":"Objective: COVID-19 may lead to a range of clinical outcomes among older people with psychiatric and medical conditions. Evidence guiding management of future outbreaks among this vulnerable population in psychiatric hospital settings are sparse. In this study, we examined the correlates of poor clinical outcomes related to COVID-19 and explored the perspectives of COVID-19 survivors hospitalized in psychiatry settings.Method: The correlates of poor clinical outcomes related to COVID-19 were examined using a retrospective chart review of 81 older people hospitalized in psychiatry settings. Correlates of clinical outcomes related to COVID-19 were assessed by multiple logistic regression models. In addition, the perspectives of 10 COVID-19 survivors were explored by qualitative interviews. The qualitative data was subject to thematic analysis.Results: Although 25.9% (n = 21) participants were asymptomatic, there was high COVID-19 related mortality (14.8%; n = 12). Vitamin-D deficiency, anticholinergic burden, and isolation policies within psychiatric wards were significantly (p < 0.05) related to COVID-19 related deaths. In qualitative interviews, participants emphasized the importance of strengthening local support networks and making vaccination centers more accessible.Conclusions: Reducing anticholinergic prescriptions and improving isolation policies may help to mitigate poor clinical outcomes. Future research investigating the impact of vitamin-D supplementation on COVID-19 related outcomes is warranted.","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/64/62/10.1177_00912174231171220.PMC10111158.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10289456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Coping strategies, emotion regulation and quality of life among psoriasis patients. 银屑病患者应对策略、情绪调节与生活质量的关系。

IF 2 4区医学

International Journal of Psychiatry in Medicine Pub Date : 2023-09-01 DOI: 10.1177/00912174231170204

Aaisha Shaukat, Samina Rashid, Mahmood Sadiq

引用次数: 0

Genetic origins of schizophrenia, child maltreatment in Kurdistan (Iran), coping strategies in psoriasis patients, problematic benzodiazepine use, and COVID-19 pandemic effects on pregnant women, older adults with psychiatric illness, and physician training. 精神分裂症的遗传起源、库尔德斯坦(伊朗)儿童虐待、牛皮癣患者的应对策略、苯二氮卓类药物使用问题、COVID-19大流行对孕妇、患有精神疾病的老年人的影响以及医生培训。

IF 2 4区医学

International Journal of Psychiatry in Medicine Pub Date : 2023-09-01 DOI: 10.1177/00912174231191051

Harold G Koenig

引用次数: 0