International Journal of Psychiatry in Medicine最新文献_第9页

Psychosexual dysfunction in male patients with cannabis dependence and synthetic cannabinoid dependence. 大麻依赖和合成大麻素依赖男性患者的性心理功能障碍。

IF 1.1 4区医学

International Journal of Psychiatry in Medicine Pub Date : 2025-01-01 Epub Date: 2024-01-28 DOI: 10.1177/00912174241230886

Abdelrahman A Asal, Doaa R Ayoub, Mohamed E Mazen, Shirin M El Makawi

{"title":"Psychosexual dysfunction in male patients with cannabis dependence and synthetic cannabinoid dependence.","authors":"Abdelrahman A Asal, Doaa R Ayoub, Mohamed E Mazen, Shirin M El Makawi","doi":"10.1177/00912174241230886","DOIUrl":"10.1177/00912174241230886","url":null,"abstract":"Objective: There are inconsistent reports regarding the relationship between cannabis use and male sexual function with almost no data about synthetic cannabinoids (SC) and their effect on male sexual functions. This study investigated psychological concerns related to male sexual functions among cannabis and SC users. The research assessed different sexual functions and aspects of sexual psychopathology in cannabis and SCs dependent men compared to controls.Method: Thirty male patients with cannabis dependence, thirty male patients with SCs dependence, and thirty matched controls from the outpatient clinic at Kasr Al Ainy hospital, Egypt, were assessed using the Structured Clinical Interview for DSM-IV TR Axis I Disorders (SCID-I), International Index of Erectile Function (IIEF), and Sexuality scale.Results: The means of IIEF questionnaire in the cannabis and SC group were significant lower (worse) than the means of the control group (P < .001) except the orgasmic function in cannabis group (P = .052). In the SCs group, sexual depression was higher and preoccupation lower than in the cannabis group (P < .020; P < .003, respectively) and control groups (P < .001; P < .001, respectively). The duration and dose of cannabis and SCs correlated significantly with sexual esteem, sexual preoccupation and all domains of IIEF.Conclusion: Cannabis and SC dependence were associated with lower erectile function, sexual desire, intercourse satisfaction and overall satisfaction, and lower orgasmic functions in the SC group than controls. Both groups showed higher sexual depression, lower sexual esteem and sexual preoccupation than controls. SC has a higher negative impact on male sexual functions and psychopathology than does cannabis.","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":" ","pages":"44-56"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139571017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Spirituality and people with psychosis: A content analysis of influential primetime television programs. 精神与精神病患者：对有影响力的黄金时段电视节目的内容分析。

IF 1.1 4区医学

International Journal of Psychiatry in Medicine Pub Date : 2025-01-01 Epub Date: 2024-03-27 DOI: 10.1177/00912174241240305

David R Hodge, Patricia R Turner

{"title":"Spirituality and people with psychosis: A content analysis of influential primetime television programs.","authors":"David R Hodge, Patricia R Turner","doi":"10.1177/00912174241240305","DOIUrl":"10.1177/00912174241240305","url":null,"abstract":"Objective: This mixed methods study examined depictions of spirituality among people with psychosis in influential television programming. Spirituality is a central strength for many people with psychosis. Yet, despite the important role media plays in shaping perceptions, little research has examined the intersection between spirituality and psychosis in the popular media.Methods: To address this gap, we conducted a content analysis of the 50 most viewed primetime fictional television shows over a 10-year period as determined by the Nielsen rating organization. Characters with psychosis were identified via keyword searches of online sources (Wikis, IMDb, etc.) and subsequently independently coded by two individuals. Characters were rated on 18 items in three domains related to demographics, life status, and character framing. Inter-rater reliability ranged from good to excellent across variables.Results: Of 120 identified characters with psychosis, just 16% (n = 19) had a spiritual identity. Analysis revealed few differences between spiritual and secular characters on demographic and life status variables. Conversely, an examination of framing variables revealed spiritual characters were comparatively less attractive, exhibited a greater negative impact on society, and were more likely to be referred to pejoratively (as a psychopath) and engage in criminal activity. Trend analysis indicated portrayals of spiritual characters decreased over time.Conclusions: The results suggest media depictions of spirituality contribute to the stigmatization of spirituality among people with psychosis, potentially preventing access to important coping resources and discouraging professional help-seeking. Primary care physicians should consider incorporating a spiritual assessment into care to determine spiritual coping assets and then support these.","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":" ","pages":"71-86"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140295080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

COVID-19 and mental health treatment in primary care: Impact of a global pandemic on a psychopharmacological collaborative care management program. COVID-19 与初级保健中的心理健康治疗：全球大流行对精神药物合作护理管理计划的影响。

IF 1.1 4区医学

International Journal of Psychiatry in Medicine Pub Date : 2025-01-01 Epub Date: 2024-06-22 DOI: 10.1177/00912174241264592

Zachary D Zuschlag, Benjamin Lord, Teagan Smith, Alexander Lengerich, Kaitlin Leonard, Yvette Guereca, Ambuj Kumar, Vanessa A Milsom

{"title":"COVID-19 and mental health treatment in primary care: Impact of a global pandemic on a psychopharmacological collaborative care management program.","authors":"Zachary D Zuschlag, Benjamin Lord, Teagan Smith, Alexander Lengerich, Kaitlin Leonard, Yvette Guereca, Ambuj Kumar, Vanessa A Milsom","doi":"10.1177/00912174241264592","DOIUrl":"10.1177/00912174241264592","url":null,"abstract":"Objective: The COVID-19 pandemic has had a profound impact on individuals with mental health (MH) disorders and on the delivery of MH services. Few studies have examined treatment models not requiring substantial changes to the delivery of services during pandemic restrictions, such as collaborative care management (CoCM) programs. Therefore, a longitudinal retrospective cohort analysis was conducted to examine the impact of the COVID-19 pandemic on a psychopharmacological CoCM program.Method: Data were collected on all U.S. Veterans enrolled in a CoCM program at a large VA during the first 10 months of the COVID-19 pandemic and compared to a matched control group one-year prior to that date. Treatment in the program pre-COVID vs. treatment during the pandemic was compared in relation to baseline symptomatology, improvements in MH symptoms, and program adherence.Results: A total of 462 Veterans were referred during the control period, compared to 351 during the same time period during the pandemic. Veterans enrolled during the first four months of each study arm, to allow for a minimum of 6 months of follow up data, had no differences in baseline symptoms of depression or anxiety between groups. Veterans receiving care during the pandemic had higher rates of program completion than pre-pandemic controls. COVID-era Veterans also had higher rates of depression response compared to controls, but no differences were observed between groups on depression remission, anxiety response, or anxiety remission.Conclusions: Psychopharmacological CoCM treatment models can successfully manage depression and anxiety with no observed decrease in the effectiveness of this intervention even during periods of unprecedented disruptions to MH services.","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":" ","pages":"33-43"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141441056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prevalence and risk factors for chronic kidney disease among older adult patients with schizophrenia in Taiwan. 台湾老年精神分裂症患者中慢性肾病的患病率和风险因素。

IF 1.1 4区医学

International Journal of Psychiatry in Medicine Pub Date : 2025-01-01 Epub Date: 2024-05-19 DOI: 10.1177/00912174241256164

Shu-Ting Chang, Jiunn-Ying Liou, Bo-Jian Wu, Hsing-Kang Chen

{"title":"Prevalence and risk factors for chronic kidney disease among older adult patients with schizophrenia in Taiwan.","authors":"Shu-Ting Chang, Jiunn-Ying Liou, Bo-Jian Wu, Hsing-Kang Chen","doi":"10.1177/00912174241256164","DOIUrl":"10.1177/00912174241256164","url":null,"abstract":"Objectives: There is an increasing incidence and prevalence of patients with chronic kidney disease (CKD) worldwide. Little is known the prevalence of CKD among older patients with schizophrenia. The purpose of this study was to investigate the prevalence of CKD and its risk factors in older adults with schizophrenia.Methods: In this cross-sectional study, a convenience sample of 240 patients with schizophrenia age 50 or older was recruited. In addition to demographic and clinical data, participants' estimated glomerular filtration rate was calculated using the Modification of Diet in Renal Disease equation based on age, sex, ethnicity, and serum creatinine level determined from a blood sample taken from participants.Results: The overall prevalence of CKD was 11.3%. Those with CKD were older, had a longer duration of psychiatric illness, a higher body mass index (BMI), and diagnoses of hypertension compared to those in the non-CKD group. Independent of other risk factors, older age and BMI were significantly associated with CKD.Conclusions: This study found that the overall prevalence of CKD in older patients with schizophrenia was 11.3%. Independent risk factors for CKD in this population were older age and higher BMI. In addition to early identification and early treatment of CKD in older patients with schizophrenia, clinicians should actively manage the risk factors identified in this study.","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":" ","pages":"87-96"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141065582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Systematic review of long-acting injectable antipsychotic medications approved from 2008 to october 2024 and agents in phase 3. 2008年至2024年10月批准的长效注射抗精神病药物和iii期药物的系统回顾。

IF 1.1 4区医学

International Journal of Psychiatry in Medicine Pub Date : 2024-12-19 DOI: 10.1177/00912174241310091

Ashley Meyer, Kyla Truman, Jayant Totlani, Catherine William, Haze Brown, Shaishav Shah, Drew Hirsch, Mohamed Salem, Tiffany Chang, Rasha Abdelsalam, Sabrina Renteria, Nathalie Murphy, Rebecca Hedrick, Itai Danovitch, Robert N Pechnick, Waguih William IsHak

{"title":"Systematic review of long-acting injectable antipsychotic medications approved from 2008 to october 2024 and agents in phase 3.","authors":"Ashley Meyer, Kyla Truman, Jayant Totlani, Catherine William, Haze Brown, Shaishav Shah, Drew Hirsch, Mohamed Salem, Tiffany Chang, Rasha Abdelsalam, Sabrina Renteria, Nathalie Murphy, Rebecca Hedrick, Itai Danovitch, Robert N Pechnick, Waguih William IsHak","doi":"10.1177/00912174241310091","DOIUrl":"https://doi.org/10.1177/00912174241310091","url":null,"abstract":"Objective: The purpose of this systematic review is to provide a detailed summary of the long-acting injectable antipsychotic medications approved by the Food and Drug Administration (FDA) between 2008 to October 2024. We aim to provide an overview of the mechanism of action, indications for both labeled and off-label uses, evidence for efficacy, dosing, and the adverse effects of each drug.Methods: Studies published from 2008 to October 1, 2024, were identified from the PubMed database, using the keywords: 'long-acting injectables' OR 'LAI*'AND 'psychopharm*\" OR 'schizophrenia' The authors conducted a focused analysis independently and reached a consensus on the recently approved long-acting injectable antipsychotic medications to be included in this systematic review. Key findings were derived from the full text in order to create the tables from selected studies.Results: A total of 13 long-acting injectable antipsychotic medications for the treatment of schizophrenia were FDA-approved between 2008 and October 1, 2024. One long-acting injectable antipsychotic is currently being investigated in a Phase 3 clinical trial. The indications, evidence, practical implementation issues, and adverse effects of each drug are discussed in this review.Conclusion: Improved understanding of newly approved long-acting injectables is critical in the management of patients with schizophrenia. The FDA approval of long-acting injectables in the past 15 years creates hopeful options for clinicians to improve clinical outcomes and quality of life for their patients.","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":" ","pages":"912174241310091"},"PeriodicalIF":1.1,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142866038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association between allostatic load and depression in patients with sleep disorders: Evidence from the National Health and Nutrition Examination Survey (NHANES). 睡眠障碍患者的异重负荷与抑郁之间的关系：来自全国健康与营养状况调查的证据。

IF 1.1 4区医学

International Journal of Psychiatry in Medicine Pub Date : 2024-11-01 Epub Date: 2024-04-01 DOI: 10.1177/00912174241244479

Yiru Li, Junli Yan, Yuhong Li

{"title":"Association between allostatic load and depression in patients with sleep disorders: Evidence from the National Health and Nutrition Examination Survey (NHANES).","authors":"Yiru Li, Junli Yan, Yuhong Li","doi":"10.1177/00912174241244479","DOIUrl":"10.1177/00912174241244479","url":null,"abstract":"Objective: Allostatic load (AL) is an indicator of the cumulative wear and tear on the body's physiological systems that can predict onset of a range of health problems. However, the relationship between AL and depression in patients with sleep disorders is unclear. This study explored the association between AL and depression in patients with sleep disorders.Methods: Using data from the 2015-2016 National Health and Nutrition Examination Survey, a total of 4618 adults aged 18 years and older in the United States were included in this cross-sectional analysis. AL was calculated using nine biological markers, with a score of ≥3 indicating a high level. Depression was assessed using the Patient Health Questionnaire-9 (PHQ-9), with a score of ≥10 indicating risk for depression. Logistic regression models were employed to analyze the relationship between AL and depression.Results: Among the 1309 participants diagnosed with sleep disorders, 212 (16.2%) were identified as being at risk for depression on the PHQ-9. A total of 55.2% (n = 117) of depressed persons had high AL levels. In the unadjusted model, AL levels were associated with depression in those with sleep disorders (OR=1.53, 95% CI = 1.14-2.05, p < 0.01). This relationship remained significant in the adjusted model (OR=1.52, 95% CI=1.11-2.10, p < 0.05), after controlling for potential confounders.Conclusion: High AL levels in patients with sleep disorders were positively associated with depression, indicating that elevated AL may increase the risk of depression in this population, or alternatively, depression may increase the risk of AL.","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":" ","pages":"670-684"},"PeriodicalIF":1.1,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140337474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Social connection and self-neglect: A case for broader exploration. 社会联系与自我忽视：需要更广泛的探索。

IF 1.1 4区医学

International Journal of Psychiatry in Medicine Pub Date : 2024-11-01 Epub Date: 2024-06-19 DOI: 10.1177/00912174241240619

Jason Burnett, Gabrielle M Hoyumpa, Jennifer E S Beauchamp, Melba A Hernandez-Tejada, Ronald Acierno, Carla Perissinotto

{"title":"Social connection and self-neglect: A case for broader exploration.","authors":"Jason Burnett, Gabrielle M Hoyumpa, Jennifer E S Beauchamp, Melba A Hernandez-Tejada, Ronald Acierno, Carla Perissinotto","doi":"10.1177/00912174241240619","DOIUrl":"10.1177/00912174241240619","url":null,"abstract":"Objective: Self-neglect (SN) is the most common report to Adult Protective Services (APS) and is associated with significant morbidity and mortality risks for older adults. Lack of instrumental support is a well-evidenced etiologic factor in the development and continuation of SN, but little is known about other modifiable social connection characteristics. The social connection framework provides evidence-based characteristics across structure, function, and quality missing from SN studies that could be identified if explored. These factors could provide prevention and intervention targets related to poor health.Methods: A narrative case study is presented using quantitative and qualitative data to explore social connection across structure, function, and quality in the context of SN.Results: The findings highlight the complexity of social connection that may be observed in SN cases reported to APS. Strategic utilization of direct and indirect social interventions to support social connection in this case are presented.Conclusion: The results from this case give rise to considerations that may be generalizable to other SN cases. Recommendations for future research on social connection in this population are provided.","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":" ","pages":"644-654"},"PeriodicalIF":1.1,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141428160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Perspectives on elder mistreatment screening and responding in emergency departments: A qualitative study with survivors. 关于急诊科筛查和应对虐待老人行为的观点：对幸存者的定性研究。

IF 16.4 4区医学

International Journal of Psychiatry in Medicine Pub Date : 2024-11-01 Epub Date: 2024-01-09 DOI: 10.1177/00912174231225765

Jason Burnett, Randi Campetti, Ruthann Froberg, Jennifer Es Beauchamp, Kristin Lees-Haggerty

{"title":"Perspectives on elder mistreatment screening and responding in emergency departments: A qualitative study with survivors.","authors":"Jason Burnett, Randi Campetti, Ruthann Froberg, Jennifer Es Beauchamp, Kristin Lees-Haggerty","doi":"10.1177/00912174231225765","DOIUrl":"10.1177/00912174231225765","url":null,"abstract":"Objective: Elder Mistreatment (EM) occurs in approximately 10% of older adults and is associated with trauma-related outcomes including depression, anxiety, posttraumatic stress disorder, and early mortality. Low screening and older adult self-reporting, especially within emergency departments, represent missed opportunities for identify and mitigate future EM occurrences and consequences. To date, no studies have obtained EM survivors' perspectives on EM screening and response practices in emergency departments.Methods: Semi-structured interviews with 19 EM survivors of those with Adult Protective Services validated EM were completed in older adults' homes. The Elder Mistreatment Emergency Department Screening and Response Tool (EM-SART) was used to guide the interview questions. All interviews were recorded, transcribed, and analyzed using qualitative thematic analyses.Results: The participants were mostly female (63%) and white (58%) with an average age of 74 years. Physical abuse accounted for 67% of the EM incidents. Three themes emerged indicating the survivor preference for (1) building rapport and approaching the older adult with compassion and care, (2) setting the context before asking the EM questions, and (3) allowing mutuality, collaborative work, and shared decision-making during the response.Conclusions: Older adults are agreeable and willing to self-report and actively engage in the EM screening and response practices in the emergency department if trauma-informed care principles are utilized.","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":" ","pages":"633-643"},"PeriodicalIF":16.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139405032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Flourishing, religion, and burnout among caregivers working in pediatric palliative care. 从事儿科姑息关怀工作的护理人员的幸福感、宗教信仰和职业倦怠。

IF 1.1 4区医学

International Journal of Psychiatry in Medicine Pub Date : 2024-11-01 Epub Date: 2024-01-27 DOI: 10.1177/00912174241229926

Annemarie E Oberholzer, Benjamin R Doolittle

{"title":"Flourishing, religion, and burnout among caregivers working in pediatric palliative care.","authors":"Annemarie E Oberholzer, Benjamin R Doolittle","doi":"10.1177/00912174241229926","DOIUrl":"10.1177/00912174241229926","url":null,"abstract":"Introduction: Providers working with children who are dying are especially prone to burnout. The enhancement of human flourishing in providers may mitigate burnout and improve quality of care. However, the relationship between job satisfaction and human flourishing has not been well studied. This project explores factors that promote human flourishing among caregivers working with children in pediatric palliative care in South Africa.Methods: A convenience sample of caregivers working in pediatric palliative care were invited to complete an anonymous, confidential survey . The survey also included open-ended questions to explore opinions and attitudes about job satisfaction, struggles, and coping.Results: Twenty-nine people from a variety of occupations and work environments completed the survey. The prevalence of burnout was 3/29 (10%). Life satisfaction (an indicator of flourishing) was associated with private religious activities (r = .38, P < .05), and carrying religion into all aspects of life (r = .44, P < .05). Burnout was not associated with life satisfaction, although power was limited. Qualitative analysis of open-ended questions revealed the following themes as factors contributing to satisfaction at work (flourishing): being able to make a difference, finding meaning and purpose, having a relationship with the children and their families, and working within the context of a multi-disciplinary team. A number of challenges to this work were also identified, including lack of resources, problems within the team, and the emotional demands of care.Conclusions: Despite job stress and the difficult work of caring for terminally ill children, several factors were associated with flourishing. These findings may help to enhance the flourishing of caregivers in the resource-challenged setting of pediatric palliative care in South Africa.","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":" ","pages":"727-739"},"PeriodicalIF":1.1,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11453028/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139566933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The association between lipid accumulation products and depression in U.S. adults: A cross-sectional study from NHANES 2005-2018. 美国成年人脂质累积产物与抑郁症之间的关系：2005-2018年美国国家健康调查（NHANES）横断面研究。

IF 1.1 4区医学

International Journal of Psychiatry in Medicine Pub Date : 2024-11-01 Epub Date: 2024-07-23 DOI: 10.1177/00912174241265559

Mengyao Dai, Yuyang Zhang, Yang Chen, Long Wang, Yanghua Tian

{"title":"The association between lipid accumulation products and depression in U.S. adults: A cross-sectional study from NHANES 2005-2018.","authors":"Mengyao Dai, Yuyang Zhang, Yang Chen, Long Wang, Yanghua Tian","doi":"10.1177/00912174241265559","DOIUrl":"10.1177/00912174241265559","url":null,"abstract":"Objective: The purpose of this study was to investigate the correlation between lipid accumulation products (LAP) and depression among adults in the United States.Methods: We analyzed data from 13,051 persons participating in the NHANES 2005-2018 cycle. The LAP index was calculated using the waist circumference (WC) and serum triglyceride (TG) levels, which reflect lipid toxicity. Participants who scored ≥10 on the Patient Health Questionnaire-9 (PHQ-9) were considered depressed. Multivariate logistic regression analyses were conducted to explore the association between the LAP index and depression. Subgroup analysis was also conducted to identify sensitive populations. Smoothed curve fitting and generalized additive model (GAM) regression were performed to verify the association between the LAP index and depression.Results: After adjusting for all potential confounders, the risk of depression increased with increasing LAP index (odds ratio [OR]=1.0011, 95% confidence interval [CI]= 1.0001-1.0021). Compared to participants in LAP quartile 1, participants in LAP quartile 3 exhibited the highest risk for depression (OR=1.43, 95% CI: 1.03-1.99). Subgroup analysis demonstrated a stronger association between the LAP index and depression in men (OR= 1.002, 95% CI= 1.001-1.004) and in those with hypertension (OR=1.002, 95% CI=1.000-1.003). Additionally, smoothed curve fitting and GAM regression demonstrated a positive linear correlation between the LAP index and depression.Conclusions: These findings suggest that individuals with a higher LAP index may be at greater risk for depression, particularly among men and those with hypertension. Further studies are required to confirm these findings.","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":" ","pages":"685-701"},"PeriodicalIF":1.1,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141753275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0