{"title":"Prevalence of the generalized anxiety disorder in Tunisia: A study of 707 primary care outpatients.","authors":"Jihene Ben Thabet, Mariem Turki, Molka Mezghani, Asma Guermazi, Mohamed Mâalej, Nada Charfi, Manel Maalej","doi":"10.1177/00912174241263235","DOIUrl":"10.1177/00912174241263235","url":null,"abstract":"<p><strong>Objective: </strong>This study examined the prevalence and correlates of generalized anxiety disorder (GAD) among primary care outpatients.</p><p><strong>Method: </strong>A multicenter, cross-sectional study was conducted that included 707 primary care outpatients being seen at 20 primary healthcare centers in Tunis and Sfax, Tunisia. The Mini International Neuropsychiatric Interview was used to identify a diagnosis of GAD. The Beck Depression Inventory was used to assess depressive symptom severity, and the Sheehan Disability Scale (SDS) was used to measure functional impairment.</p><p><strong>Results: </strong>The prevalence of GAD was 11%. GAD was positively correlated with female gender (<i>P</i> = .005), family history of psychiatric disorder (<i>P</i> < .001), personal history of suicide attempt (<i>P</i> = .019), and depressive symptoms (<i>P</i> < .001). Based on the SDS, severe to very severe functional limitations were reported at work (56.4%), in social life (60.2%), and family life (73.1%) among GAD patients.</p><p><strong>Conclusion: </strong>This study indicated a relatively high prevalence of GAD among primary care patients in Tunisia. Risk factors were also determined that may help to identify these patients. This information may help primary care physicians recognize this diagnosis and provide timely referrals to mental health professionals to prevent complications and maximize quality of life.</p>","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":" ","pages":"187-202"},"PeriodicalIF":1.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141428159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Interrelationship between depression and low back pain-related disability among patients seen at orthopedic clinics in Al Qassim region, Saudi Arabia: Prevalence, severity, and determinants.","authors":"Naif Abdullah Alsughier","doi":"10.1177/00912174241287332","DOIUrl":"10.1177/00912174241287332","url":null,"abstract":"<p><strong>Objectives: </strong>Low back pain (LBP) is a widespread health problem that poses a severe economic burden on both affected patients and the societies in which they live. The purpose of this study was to examine the association between depression and low back pain among patients seen at an orthopedic clinic and determine the association with physical disability.</p><p><strong>Methods: </strong>A cross-sectional study was carried out in the orthopedic clinics of Al-Badaya General Hospital in the Qassim Region, Saudi Arabia. All patients with LBP seen in the clinic between April and June 2024 were included in the study. A questionnaire was administered that collected demographic information, asked about medical history and behaviors, and included the Arabic-validated version of the Roland-Morris Disability Questionnaire (RMDQ) and the Patient Health Questionnaire (PHQ-9; depression). Multivariate logistic regression analysis was performed to identify correlates of depression.</p><p><strong>Results: </strong>A total of 365 patients were included in the study. Age ranged between 18 and 85 years, with a mean of 47.9 years (55.6% female). The overall prevalence of depression was 56.2%; 40.3% was mild, 13.2% moderate, and 2.7% moderately severe or severe based on PHQ-9 cutoff scores. Patients with moderately severe/severe depression had the highest disability score, while those with no depression had the lowest disability score. Multivariate logistic regression analysis revealed that with each unit increase in disability score, there was a 20% increase in depression (adjusted odds ratio = 1.20, 95% CI = 1.14-1.26, <i>P</i> < 0.001).</p><p><strong>Conclusion: </strong>Depression, although mostly mild, was common in this clinic sample of orthopedic patients with chronic LBP and was frequently associated with disability. Disability can be a serious complication of chronic LBP and is often closely linked with depression. As a result, patients with chronic LBP seen at orthopedic clinics in Saudi Arabia (and likely other Middle Eastern countries) should be screened for depression and managed accordingly.</p>","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":" ","pages":"155-169"},"PeriodicalIF":1.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142299970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prevalence and correlates of insomnia and fatigue in patients with type 2 diabetes in Jordan.","authors":"Salam Shannag, Sereene Al-Jabari, Lana Sbitan, Jafar Alsheyyab, Sa'ed Zeitoon, Suzan Hanandeh, Mervat Alsous, Omar Gammoh","doi":"10.1177/00912174241269543","DOIUrl":"10.1177/00912174241269543","url":null,"abstract":"<p><strong>Objective: </strong>The present study examined the prevalence and correlates of insomnia and fatigue in patients with type-2 diabetes in Jordan.</p><p><strong>Methods: </strong>This was a cross-sectional online study involving a convenience sample of 390 patients with type-2 diabetes. Insomnia was assessed by the Insomnia-Severity Index (ISI-A) and fatigue by the Brief Fatigue Inventory (BFI-A).</p><p><strong>Results: </strong>Severe insomnia was present in 132 patients (33.8%), and was correlated with length of diabetes (diagnosis >5 years) (OR = 2.13, 95% CI = 1.19-3.81, <i>P</i> = 0.01), presence of uncontrolled diabetes (OR = 1.97, 95% CI = 1.45-2.69, <i>P</i> < 0.001), taking gabapentin (OR = 2.07, 95% CI = 1.07-4.01, <i>P</i> = 0.003), and age (<40 years) (OR = 0.30, 95% CI = 0.13-0.69, <i>P</i> = 0.005). Significant fatigue was also prevalent and correlated with gender (female) (B = 9.25, t = 4.48, <i>P</i> < 0.001), age (<40 years) (B = 7.56, t = 2.56, <i>P</i> = 0.01), a diagnosis of hypertension (B = 4.74, t = 2.03, <i>P</i> = 0.04), uncontrolled diabetes (B = 7.21, t = 4.82, <i>P</i> < 0.001), and taking a sulfonylurea (B = 8.03, t = 3.37, <i>P</i> < 0.001), carbamazepine (B = 10.93, t = 2.65, <i>P</i> = 0.008), or gabapentin (B = 12.60, t = 3.83, <i>P</i> < 0.001).</p><p><strong>Conclusion: </strong>Given the high prevalence of insomnia and fatigue in this population, increased attention by primary healthcare providers to these symptoms in diabetic patients is warranted, particularly in developing countries such as Jordan.</p>","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":" ","pages":"143-154"},"PeriodicalIF":1.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141767992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Omar Gammoh, Mohammad Mansour, Suha Al Hababbeh, Wail Ennab, Alaa A A Aljabali, Murtaza M Tambuwala, Ammena Y Binsaleh, Sireen Abdul Rahim Shilbayeh
{"title":"Insomnia and fibromyalgia-like symptoms among women diagnosed with relapsing remitting multiple sclerosis in Jordan: Prevalence and correlates.","authors":"Omar Gammoh, Mohammad Mansour, Suha Al Hababbeh, Wail Ennab, Alaa A A Aljabali, Murtaza M Tambuwala, Ammena Y Binsaleh, Sireen Abdul Rahim Shilbayeh","doi":"10.1177/00912174241255420","DOIUrl":"10.1177/00912174241255420","url":null,"abstract":"<p><strong>Objective: </strong>This study examined the prevalence and correlates of fibromyalgia and insomnia in a convenience sample of Women with Multiple Sclerosis (WMS).</p><p><strong>Methods: </strong>The study was cross-sectional in design and recruited a sample of 163 women with Relapsing-Remitting Multiple Sclerosis (RRMS). Fibromyalgia was assessed using the Patient Self-Report Survey (PSRS), which follows criteria outlined by the American College of Rheumatology. Insomnia was measured using the Arabic version of the Insomnia Severity Index (ISI-A).</p><p><strong>Results: </strong>The prevalence of fibromyalgia and insomnia was 28.2% (n = 46) and 46.3% (n = 76), respectively. Multivariate analyses were used to determine significant independent correlates. Fibromyalgia was associated with age above 40 years (OR = 2.29, 95% CI = 1.01-5.18, <i>P</i> = .04), high school education (OR = 3.69, 95% CI = 1.62-8.37, <i>P</i> = .002), and non-use of analgesics (OR = .02, 95% CI = .004-.21, <i>P</i> = .001). Insomnia symptoms were significantly associated only with age above 40 years (OR = 2.16, 95% CI = 1.16-4.04, <i>P</i> = .01).</p><p><strong>Conclusion: </strong>These findings highlight the need for increased attention by primary care physicians towards diagnosing and treating fibromyalgia and insomnia among women with RRMS in Jordan, particularly for older women.</p>","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":" ","pages":"131-142"},"PeriodicalIF":1.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141077097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sai Shashank Gudla, Siva Krishna Adithya Bhumireddy, Anil Kumar Vadaga
{"title":"Tramadol and mental health: A systematic review of case reports describing psychological side-effects.","authors":"Sai Shashank Gudla, Siva Krishna Adithya Bhumireddy, Anil Kumar Vadaga","doi":"10.1177/00912174251322356","DOIUrl":"https://doi.org/10.1177/00912174251322356","url":null,"abstract":"<p><strong>Objective: </strong>Tramadol is a synthetic opioid widely used in clinical practice to treat moderate to severe pain. While it is considered safer than traditional opioids, growing concerns have emerged regarding its adverse psychological effects. This systematic review examined tramadol-induced psychological side effects, identified risk factors, and evaluated possible underlying mechanisms that might help to guide safer clinical use.</p><p><strong>Methods: </strong>A systematic search was conducted in PubMed, Scopus, Web of Science, and Google Scholar using the related keywords of tramadol and psychological effects. This review primarily focused on case reports, which were included if they provided detailed accounts of tramadol-induced mental health side-effects. Two independent reviewers screened the studies, and data was extracted on patient demographics, details of tramadol usage, psychological outcomes, and risk factors. The quality of the case reports was assessed using the Joanna Briggs Institute (JBI) scale.</p><p><strong>Results: </strong>The review found that tramadol is associated with a range of psychological symptoms, including manic episodes, hypomania, serotonin syndrome, psychosis, and cognitive impairment. Risk factors included age, pre-existing psychiatric conditions, polydrug use, and prolonged tramadol use. Elderly individuals and those with psychiatric histories were particularly vulnerable.</p><p><strong>Conclusion: </strong>Tramadol has the potential to cause serious psychological side effects, prompting cautious prescription, especially in vulnerable populations. Clinicians should closely monitor patients for these adverse effects, and further research is needed to understand the mechanisms involved and to reduce the psychological site-effects resulting from tramadol use.</p>","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":" ","pages":"912174251322356"},"PeriodicalIF":1.1,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143450893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Addressing severe alcohol withdrawal with bromocriptine: A case series.","authors":"Sayantan Chattopadhyay, Ayan Basak, Sukriti Mukherjee","doi":"10.1177/00912174251321962","DOIUrl":"https://doi.org/10.1177/00912174251321962","url":null,"abstract":"<p><strong>Objective: </strong>Alcohol withdrawal syndrome poses a significant health burden worldwide, with its prevalence steadily rising in countries like India due to high rates of alcohol use disorders. The treatment landscape for alcohol withdrawal syndrome is evolving with the introduction of bromocriptine offering a promising adjunctive treatment for patients resistant to standard benzodiazepine therapy.</p><p><strong>Methods: </strong>We report two cases from India of severe alcohol withdrawal syndrome successfully treated with bromocriptine.</p><p><strong>Results: </strong>There were clinically significant improvements in both patients with regard to Alcohol Withdrawal Symptoms in a relatively short time span.</p><p><strong>Conclusions: </strong>Bromocriptine represents an addition to the therapeutic options for alcohol withdrawal syndrome management, offering symptom relief, improving clinical outcomes, and addressing the neuropsychiatric burden associated with the condition.</p>","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":" ","pages":"912174251321962"},"PeriodicalIF":1.1,"publicationDate":"2025-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143434308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mayuresh Chaudhari, Luis Mendez, Rene L Olvera, Sudha Seshadri, Antonio L Teixeira
{"title":"Cardiovascular disease and bipolar disorder: A review of pathophysiology and treatment implications.","authors":"Mayuresh Chaudhari, Luis Mendez, Rene L Olvera, Sudha Seshadri, Antonio L Teixeira","doi":"10.1177/00912174251316947","DOIUrl":"https://doi.org/10.1177/00912174251316947","url":null,"abstract":"<p><strong>Objective: </strong>Despite the well-established increased risk of cardiovascular mortality in individuals with bipolar disorder (BD), prevention and treatment of cardiovascular risk factors and diseases have been largely overlooked in this population. This manuscript reviews the pathophysiological basis of the connection between BD and cardiovascular diseases, highlighting their shared mechanisms, reciprocal interactions, and relevant prevention and treatment strategies.</p><p><strong>Methods: </strong>For this narrative review, a search was carried out on PubMed using the keywords bipolar disorder, cardiovascular diseases, and cardiovascular risk factors.</p><p><strong>Results: </strong>The increased frequency of cardiovascular morbidity in BD can be attributed to overlapping biological and psychosocial mechanisms. These mechanisms are complex and involve both direct effects of BD and indirect effects mediated by lifestyle and pharmacological factors. Cardiovascular diseases also significantly exacerbate the clinical course of BD and increase morbidity and healthcare costs; thus, their effective management can improve psychiatric outcomes and vice versa. However, patients with BD frequently encounter healthcare barriers.</p><p><strong>Conclusion: </strong>Awareness initiatives and research on integrated care are needed to determine the best strategies for improving cardiovascular and psychiatric outcomes in individuals with BD.</p>","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":" ","pages":"912174251316947"},"PeriodicalIF":1.1,"publicationDate":"2025-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143030279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Psychiatric problems in medical patients relevant to primary care physicians and mental health providers.","authors":"Harold G Koenig","doi":"10.1177/00912174241297503","DOIUrl":"10.1177/00912174241297503","url":null,"abstract":"","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":" ","pages":"3-6"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142512222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abdi Mahamed Muhummed, Meka Kedir Jibril, Ahmed Adem Yimam, Seid Yimam Ali
{"title":"Prevalence and correlates of post-traumatic stress disorder among internal displaced people in Qoloji Camps, Somali regional state, Eastern Ethiopia.","authors":"Abdi Mahamed Muhummed, Meka Kedir Jibril, Ahmed Adem Yimam, Seid Yimam Ali","doi":"10.1177/00912174241232001","DOIUrl":"10.1177/00912174241232001","url":null,"abstract":"<p><strong>Objectives: </strong>This study assessed the prevalence and correlates of post-traumatic stress disorder (PTSD) among internally displaced people (IDP) in the Qoloji Camp, Somali Regional State, Eastern Ethiopia.</p><p><strong>Methods: </strong>A community-based cross-sectional study was conducted from October 20 to November 5, 2021. The study utilized systematic random sampling to identify 410 IDP participants from the Qoloji Camp. PTSD was measured using the PTSD Check-list for DSM-5 (PCL-5). Bivariate analysis was performed to determine the crude odds ratio, and multivariate analysis was used to calculate adjusted odds ratios for associations between PTSD and independent variables.</p><p><strong>Results: </strong>A total of 404 participants were interviewed (98.5% response rate). The estimated prevalence of PTSD symptoms was 41.1%. In the multivariate logistic regression analysis, several factors were significantly associated with PTSD: being female (AOR = 2.5, 95% CI = 1.39-4.44), lack of food and water (AOR = 2.2, 95% CI = 1.17, 4.23), destruction of personal property (AOR = 3.1, 95% CI = 1.62-6.09), and experiencing torture or beatings (AOR = 1.8, 95% CI = 1.01-3.28).</p><p><strong>Conclusion: </strong>This study found a high prevalence of PTSD symptoms among IDPs, with factors such as female sex, property destruction, deprivation of essential goods and services, and experiences of torture or beatings significantly associated with those symptoms. To address these findings, prioritizing the well-being of IDPs with a specific focus on women, on-site screening, and the establishment of a referral system to facilitate access to specialized care are essential to enhance the overall mental health of such persons.</p>","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":" ","pages":"17-32"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139730898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Omar Gammoh, Esam Qnais, Hanan Abu Alshaikh, Mohammad Mansour, Suha Al-Habahbeh, Feras Weshah, Wail Ennab, Badriyah S Alotaibi, Abdelrahim Alqudah
{"title":"PTSD symptoms among patients with multiple sclerosis in Jordan during October 7th Gaza war outbreak.","authors":"Omar Gammoh, Esam Qnais, Hanan Abu Alshaikh, Mohammad Mansour, Suha Al-Habahbeh, Feras Weshah, Wail Ennab, Badriyah S Alotaibi, Abdelrahim Alqudah","doi":"10.1177/00912174241272680","DOIUrl":"10.1177/00912174241272680","url":null,"abstract":"<p><strong>Objective: </strong>Clinicians have noted that the ongoing war on Gaza has had a psychological impact on people with multiple sclerosis (PwMS) whose mental health is particularly vulnerable during stressful times such as these. The present study sought to examine the prevalence and correlates of posttraumatic stress disorder (PTSD) symptoms among PwMS in Jordan during the Gaza war outbreak.</p><p><strong>Methods: </strong>This was a cross-sectional study involving 171 patients (PwMS) out of 372 patients approached (46% response rate) who were being seen in the MS unit at Al Bashir Hospital, Ammann, Jordan. Inclusion criteria required that participants had been following daily news updates of the October 7 war in Gaza during a period of 4 months.</p><p><strong>Results: </strong>Of participants, 125 (73.1%) were female, 98 (57.3%) were on therapy for less than five years, and 30 (17.5%) reported having a relapse during the past 6 months. Significant PTSD symptoms were identified in 58.5% (100 of 171 participants). Those at higher risk were the unemployed (OR = 2.14, 95% CI = 1.13-4.07, <i>P</i> = 0.02), whereas patients receiving dimethyl fumarate (19.9%) were at lower risk (OR = 0.43, 95% CI = 0.19-0.94, <i>P</i> = 0.02).</p><p><strong>Conclusion: </strong>The high rate of significant PTSD symptoms among people with MS in this study underscores the need for attention by primary care providers and the implementation of a comprehensive multidisciplinary approach to optimize the mental well-being of this fragile population.</p>","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":" ","pages":"7-16"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141898764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}