Fu Zhang, Tianying Tang, Jian Liu, Wei Wang, Yifan Wang, Yangtian Yan, Jiaming Liu, Huamin Liu
{"title":"Calcium and vitamin D supplements and burnout of anesthesiologists: National cross-sectional study from China.","authors":"Fu Zhang, Tianying Tang, Jian Liu, Wei Wang, Yifan Wang, Yangtian Yan, Jiaming Liu, Huamin Liu","doi":"10.1177/00912174241262120","DOIUrl":"https://doi.org/10.1177/00912174241262120","url":null,"abstract":"<p><strong>Objective: </strong>Job burnout among anesthesiologists has been consistently high. This study evaluated the association of calcium and vitamin D supplementation with burnout among Chinese anesthesiologists.</p><p><strong>Method: </strong>A cross-sectional online survey was conducted during April and May 2023. Burnout was evaluated using the Maslach Burnout Inventory, which assesses emotional exhaustion, depersonalization, and low personal accomplishment. Data on calcium and vitamin D supplementations were self-reported. Sociodemographic information and medical history were also assessed. Binary and ordinal logistic regression were used to evaluate the risk of burnout and burnout levels, respectively. The relative excess risk due to interaction and the attributable proportion due to interaction were examined to determine the synergistic effects of calcium and vitamin D supplementations on burnout risk.</p><p><strong>Results: </strong>Among the 4222 invited anesthesiologists, 3766 submitted eligible questionnaires. Approximately 49.8% met the criteria for general burnout. Among anesthesiologists with burnout, 58.4% experienced emotional exhaustion, 35.8% depersonalization, and 61.2% low personal accomplishment. Anesthesiologists receiving calcium supplementation had a decreased risk of emotional exhaustion (OR = .83, 95% CI = .70-.99). Supplementation of vitamin D with or without calcium was not associated with overall burnout and any of its dimensions. No additive interaction of calcium and vitamin D on burnout was observed.</p><p><strong>Conclusions: </strong>Job burnout among anesthesiologists is of concern in China. Burnout is negatively associated with calcium supplementation but not with vitamin D. Further research is warranted to confirm the mechanism and causal relationship.</p>","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":" ","pages":"912174241262120"},"PeriodicalIF":1.1,"publicationDate":"2024-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141433268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Psychosocial factors predicting symptoms of depression and anxiety in allogeneic hematopoietic stem cell transplant recipients in Japan.","authors":"Takashi Imamura, Takeshi Sudo, Yasushi Orihashi, Yuki Takahashi, Yuichi Onishi, Makoto Onizuka, Katsunaka Mikami, Yasunori Ueda, Kenji Yamamoto","doi":"10.1177/00912174231191672","DOIUrl":"10.1177/00912174231191672","url":null,"abstract":"<p><strong>Objective: </strong>We explored whether a patient's psychosocial background before allogeneic hematopoietic stem cell transplantation (allo-HSCT) could predict the occurrence of psychiatric symptoms during treatment and after hospital discharge.</p><p><strong>Method: </strong>Logistic regression analysis was performed using INTERMED, a scale that comprehensively evaluates psychological factors such as psychiatric history, current mental status, and coping skills, and social factors such as social participation status, relationships with others, and living environment, which were used as independent variables. The Center for Epidemiologic Studies Depression Scale was used to measure depression, while the Profile of Mood States was used to measure anxiety and other symptoms. Both measures were used as dependent variables and were administered upon clean room admission, during clean room stay, at clean room discharge, and at 3, 6, and 12 months after hospital discharge.</p><p><strong>Results: </strong>Participants included 70 patients (45 males and 25 females, mean age 53.3 ± 12.3 years). Thirty-eight patients participated in the program for the entire period, up to 12 months after hospital discharge. The total score on the Japanese version of the INTERMED and psychological factor scores assessed at baseline were significant predictors of depressed mood on discharge; however, there were no significant predictors of scores on the Profile of Mood States.</p><p><strong>Conclusions: </strong>A comprehensive pretransplant evaluation of psychosocial background can help predict the appearance of psychiatric symptoms after allo-HSCT. In patients who are expected to develop psychiatric symptoms after allo-HSCT, it is important to consider early intervention by a specialist and close monitoring by a medical team.</p>","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":" ","pages":"287-302"},"PeriodicalIF":2.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10324851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Falmata Baba Shettima, Musa Abba Wakil, Taiwo Lateef Sheikh, Mohammed Abdulaziz, Isa Bukar Rabbebe, Ibrahim Abdu Wakawa, Ogualili Placidus
{"title":"Prevalence and correlates of sexual dysfunction among patients with schizophrenia spectrum disorder on antipsyhotic medications in Maiduguri, Northeastern Nigeria.","authors":"Falmata Baba Shettima, Musa Abba Wakil, Taiwo Lateef Sheikh, Mohammed Abdulaziz, Isa Bukar Rabbebe, Ibrahim Abdu Wakawa, Ogualili Placidus","doi":"10.1177/00912174231196612","DOIUrl":"10.1177/00912174231196612","url":null,"abstract":"<p><strong>Objectives: </strong>Despite the importance of a satisfying sexual life, most patients with schizophrenia spectrum disorders do not discuss sexual issue with their clinicians. The current study seeks to determine the prevalence and socio-clinical correlates of sexual dysfunction among patients with schizophrenia spectrum disorders receiving typical and atypical antipsychotic medications. The second objective is to determine the frequency and correlates of specific sexual dysfunction (desire, arousal, erection/lubrication and orgasm) by gender and drug type using the Arizona Sexual Experience Scale.</p><p><strong>Methodology: </strong>This cross-sectional study used standardized structured interviewer based survey to assess sexual dysfunction among patients with schizophrenia that are both sexually active and inactive at a tertiary hospital in Maiduguri from December 2020 to April 2021. Participants were also assayed for prolactin using ELISA Kit for a possible association with sexual dysfunction.</p><p><strong>Results: </strong>The overall prevalence of sexual dysfunction among patients with schizophrenia spectrum disorder receiving antipsychotics was 34% with patients on typical and atypical antipsychotics reporting rates of 36.8% and 24.6%, respectively. Among the typical and atypical antipsychotics, patients receiving haloperidol (40.3%) and risperidone (37.5%) reported a relatively higher frequency of sexual dysfunction compared to those receiving clozapine (18.2%). Independent correlates of sexual dysfunction were: female gender (OR = 1.89, 95% CI = 1.17-3.06; <i>P</i> = .010), being unmarried (OR = 1.51, 95% CI = 1.17-1.96; <i>P</i> = .001), pseudoparkinsonism (OR = 1.66, 95% CI = 1.02-2.69; <i>P</i> = .008), prolactin (OR = 2.15, 95% CI = 1.34-3.43; <i>P</i> = .001) and severity of illness (OR = 1.34, 95% CI = 1.03-1.75; <i>P</i> = .030).</p><p><strong>Conclusion: </strong>Sexual dysfunction is prevalent among patients with schizophrenia spectrum disorder receiving either typical or atypical antipsychotics.</p>","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":" ","pages":"373-392"},"PeriodicalIF":2.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10422269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sema Baykara, Aslı Kazğan, Hakan Yıldırım, Muhammed Fatih Tabara, Halim Ömer Kaşıkcı, Denizhan Danacı Keleş
{"title":"Retinal changes in generalized anxiety disorder patients.","authors":"Sema Baykara, Aslı Kazğan, Hakan Yıldırım, Muhammed Fatih Tabara, Halim Ömer Kaşıkcı, Denizhan Danacı Keleş","doi":"10.1177/00912174231209771","DOIUrl":"10.1177/00912174231209771","url":null,"abstract":"<p><strong>Objective: </strong>Optical coherence tomography (OCT) is a method that allows high-resolution cross-sectional imaging of biological tissues. It was suggested that changes in the cranial structure or functions would be reflected in the retina. OCT has been an important method in the diagnosis and follow-up of diseases via morphometric or quantitative retinal measurements. Free radicals, inflammatory processes, and neurotransmission disorders play a role in the etiology of generalized anxiety disorder (GAD). The study aimed to demonstrate the retinal changes in GAD patients due to neurodegeneration based on the comparison of the OCT data of the GAD patients and controls, and the differences between OCT findings of GAD patients and those of controls.</p><p><strong>Methods: </strong>The study group included 21 GAD patients. The control group included 21 individuals without any known psychiatric or organic disease, including eye diseases.</p><p><strong>Results: </strong>There was a statistically significant difference between the macular volumes (MV) of the GAD and control groups, the macular volume was lower in the GAD group. There were positive correlations between BDI scores and MV, GCLT, RNFLT-i, RNFLT-n, between BAE scores and (RNFLT-n), and between the CGI severity scale scores and MV, RNFLT-n, and RNFLT-t.</p><p><strong>Conclusion: </strong>OCT analysis of the GAD patients demonstrated that MV values were lower when compared to the control group. Patients with GAD should be screened for these retinal changes. OCT, a simple, non-invasive, and relatively inexpensive method could be employed as a supplementary method in the follow-up of GAD patients.</p>","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":" ","pages":"270-286"},"PeriodicalIF":2.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49693510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Religious involvement and psychological well-being in the Middle East.","authors":"Harold G Koenig, Saad Al Shohaib","doi":"10.1177/00912174231197548","DOIUrl":"10.1177/00912174231197548","url":null,"abstract":"<p><strong>Objective: </strong>There is growing evidence that religious involvement is associated with better mental health in Christian Western countries. Whether the same is true in Middle Eastern countries whose populations are largely Muslim is less clear. The present study examined the association between religiosity and psychological well-being in the Middle East.</p><p><strong>Methods: </strong>This cross-sectional study involved nationally representative samples of adults aged 18 or older in Egypt (n = 3496), Tunisia (n = 3070), and Turkey (n = 3019) (Wave 1 of Middle Eastern Values Panel Study). Data on psychological well-being (life satisfaction, happiness, and optimism) were available on 8835-8886 participants. Bivariate analyses and multivariate analyses were conducted, controlling for age, gender, education, employment status, marital status, financial satisfaction, economic class, country, and Muslim religious affiliation. Interactions with gender were also examined.</p><p><strong>Results: </strong>Most participants (95%) reported a Muslim affiliation. Bivariate analyses indicated a positive association between overall religiosity (the primary predictor) and life satisfaction (r = .12), happiness (r = .13) and optimism (r = .19) (<i>P</i> < .0001). Multivariate analyses indicated a significant relationship between overall religiosity and life satisfaction (B = .046, SE = .005), happiness (OR = 1.03, 95% CI = 1.02-1.04), and optimism (B = .054, SE = .005). A significant interaction between gender and religiosity was found for life satisfaction (B = -.025, SE = .009, <i>P</i> = .007), such that the association was stronger in males than in females. For happiness and optimism, trends were in the same direction.</p><p><strong>Conclusions: </strong>Small but significant associations between overall religiosity (beliefs and practices) and psychological well-being were found in this largely Muslim Middle Eastern sample. Prospective studies are needed to determine the causal direction of these relationships.</p>","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":" ","pages":"341-359"},"PeriodicalIF":2.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10052198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
George U Eleje, Charlotte B Oguejiofor, Sunday O Oriji, Kingsley E Ekwuazi, Emmanuel O Ugwu, Emeka P Igbodike, Divinefavour E Malachy, Ekeuda U Nwankwo, Christian E Onah, Joseph O Ugboaja, Joseph I Ikechebelu, Uchenna I Nwagha
{"title":"Depression, anxiety, and stress and adverse pregnancy outcomes in pregnant women with history of recurrent pregnancy loss in Nigeria.","authors":"George U Eleje, Charlotte B Oguejiofor, Sunday O Oriji, Kingsley E Ekwuazi, Emmanuel O Ugwu, Emeka P Igbodike, Divinefavour E Malachy, Ekeuda U Nwankwo, Christian E Onah, Joseph O Ugboaja, Joseph I Ikechebelu, Uchenna I Nwagha","doi":"10.1177/00912174231199215","DOIUrl":"10.1177/00912174231199215","url":null,"abstract":"<p><strong>Objective: </strong>The primary purpose of this study was to examine whether pregnant women with a history of recurrent pregnancy loss (RPL) are more likely to experience moderate-to-severe depression, anxiety, or stress symptoms than pregnant women without a history of RPL. The secondary purpose was to determine whether women with prior RPL experienced more unfavorable pregnancy outcomes if they had depression, anxiety, or stress.</p><p><strong>Methods: </strong>A prospective case-control study was conducted that included 47 pregnant women with a history of RPL and 94 pregnant women without prior RPL. Participants 20 weeks of gestation or earlier were included. Both groups completed the Depression, Anxiety, and Stress Scale (DASS-21), and were followed up until delivery to determine the pregnancy outcomes. Multivariate logistic regression was used to compare adverse pregnancy outcomes.</p><p><strong>Result: </strong>Among the 47 women with prior RPL, 10 had primary RPL (two or more miscarriages without a successful pregnancy) and 37 secondary RPL (two or more miscarriages with a history of successful pregnancy). RPL was significantly associated with moderate-to-severe levels of depression (<i>P</i> < .001), anxiety (<i>P</i> < .001), and stress (<i>P</i> < .001). Among the RPL group, high stress level was significantly associated with repeat miscarriage (adjusted odds ratio (AOR) = 5.28, 95%CI = 1.25-100.0, <i>P</i> = .03) and preterm labor (AOR = 6.07, 95%CI = 1.61-100.0, <i>P</i> = .04). Depression and anxiety were not associated with adverse pregnancy outcomes.</p><p><strong>Conclusion: </strong>Pregnant women with a history of RPL had considerably higher rates of moderate-to-severe depression, anxiety, and stress. Repeat miscarriage and preterm labor were considerably higher among pregnant women with RPL who were experiencing high stress levels at baseline.</p>","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":" ","pages":"303-324"},"PeriodicalIF":2.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10166650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sumayah A Aljhani, Razan A Almeshal, Emtenan A Almeshal, Alhanuf M Alofea, Adim S Alenizi
{"title":"Predictors of postpartum depression and its association with sleep quality among mothers in Qassim, Saudi Arabia: A descriptive cross-sectional study.","authors":"Sumayah A Aljhani, Razan A Almeshal, Emtenan A Almeshal, Alhanuf M Alofea, Adim S Alenizi","doi":"10.1177/00912174231202932","DOIUrl":"10.1177/00912174231202932","url":null,"abstract":"<p><strong>Objective: </strong>This cross-sectional study aims to examine the prevalence of postpartum depression (PPD) and sleep problems, their relationship, and the characteristics associated with depression/insomnia in Qassim, Saudi Arabia.</p><p><strong>Methods: </strong>An online survey was administered to a convenience sample of 395 mothers who had given birth within the preceding year. The survey comprised demographic characteristics, pregnancy and childbirth characteristics, depression (via the Edinburgh Postnatal Depression Scale; EPDS), and sleep quality (via the Pittsburgh Sleep Quality Index; PSQI).</p><p><strong>Results: </strong>Nearly two-thirds of respondents (62.3%) had PPD, while 92.2% experienced poor sleep quality. Both scales demonstrated a statistically significant positive correlation. Participants with previous PPD, peripartum depression, a personal or family history of other depression, those bottle-feeding their infants, or who had a change in sleep pattern scored significantly higher on the EPDS and had poorer PSQI scores. Respondents with a history of mental illness, pregnancy or delivery complications, those who lacked support, or gave birth to unhealthy newborns also had significantly higher EPDS scores.</p><p><strong>Conclusions: </strong>PPD and poor sleep quality were highly prevalent among mothers living in the Qassim region of Saudi Arabia. Not surprisingly, PPD was strongly correlated with poor sleep quality. Postpartum counseling for mothers during the first year after delivery is necessary to decrease the risk of developing depressive symptoms and poor sleep quality. Screening for sleep-related difficulties and depression in prenatal and postnatal programs may help prevent the development of depressive disorder among postpartum women in this region of Saudi Arabia (or other areas of the Middle East).</p>","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":" ","pages":"325-340"},"PeriodicalIF":2.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41162645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Omar Gammoh, Ahmed Al-Smadi, Mohammad Mansour, Wail Ennab, Suha Al Hababbeh, Ghaith Al-Taani, Mervat Alsous, Alaa Aa Aljabali, Murtaza M Tambuwala
{"title":"The relationship between psychiatric symptoms and the use of levetiracetam in people with epilepsy.","authors":"Omar Gammoh, Ahmed Al-Smadi, Mohammad Mansour, Wail Ennab, Suha Al Hababbeh, Ghaith Al-Taani, Mervat Alsous, Alaa Aa Aljabali, Murtaza M Tambuwala","doi":"10.1177/00912174231206056","DOIUrl":"10.1177/00912174231206056","url":null,"abstract":"<p><p><b>Background:</b> Mental health in people with epilepsy (PWE) is often overlooked, especially in developing countries.<b>Purpose:</b> Consequently, the current work had two objectives: (1) to estimate the burden of depression, anxiety, insomnia, and stress, and (2) to examine the association of these psychiatric/psychological symptoms with levetiracetam and other relevant clinical factors in a cohort of Jordanian PWE.<b>Research Design:</b> This is a cross-sectional study. The demographic and clinical data were recorded. Depression was measured by the Patient Health Questionnaire-9 (PHQ-9, Arabic-validated version) and anxiety by the General Anxiety Disorder-7 (GAD-7, Arabic-validated version). The insomnia severity index (ISI-A, Arabic version) was used to assess sleep quality, and the Perceived Stress Scale (PSS-A, Arabic version) was used to measure perceived stress.<b>Study Sample:</b> Data were analyzed from 280 patients, of which 178 (63.6%) received levetiracetam as monotherapy or as adjuvant.<b>Results:</b> Depression was reported in 150 (53.6%), anxiety in 110 (39.3%), insomnia in 131 (46.8%), and clinically significant stress in 211 (75.4%). At univariate analysis, levetiracetam was not associated with psychiatric symptoms. Multivariate logistic regression revealed that severe depressive symptoms were associated with family history (OR = 2.47, 95% CI = 1.42-4.33, <i>P</i> = .001) and seizure type (OR = 1.69, 95% CI = 1.01-2.80, <i>P</i> = .04), severe anxiety symptoms were associated with family history (OR = 1.90, 95% CI = 1.12-3.23, <i>P</i> = .01), severe insomnia was associated with seizure type (OR = 2.16, 95% CI = 1.33-3.5, <i>P</i> = .002) and severe stress was associated with marital status (OR = 2.37, 95% CI = 1.31-4.29, <i>P</i> = .004).<b>Conclusions:</b> The high psychological burden of PWE is a challenging issue that requires attention and prompt action to control its risk factors. Levetiracetam was not associated with psychiatric symptoms in this study.</p>","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":" ","pages":"360-372"},"PeriodicalIF":2.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11044508/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41219116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sebastian Schröder, Martin Schulze Westhoff, Tabea Pfister, Stefan Bleich, Felix Wedegärtner, Tillmann Hc Krüger, Johannes Heck, Adrian Groh
{"title":"Characteristics of clinical-pharmacological recommendations in psychiatry in Germany.","authors":"Sebastian Schröder, Martin Schulze Westhoff, Tabea Pfister, Stefan Bleich, Felix Wedegärtner, Tillmann Hc Krüger, Johannes Heck, Adrian Groh","doi":"10.1177/00912174231177230","DOIUrl":"10.1177/00912174231177230","url":null,"abstract":"<p><strong>Objective: </strong>Psychiatric patients in general, and elderly psychiatric patients in particular, are at risk of adverse drug reactions due to comorbidities and inappropriate polypharmacy. Interdisciplinary and clinical-pharmacologist-led medication reviews may contribute to medication safety in the field of psychiatry. In this study, we reported the frequency and characteristics of clinical-pharmacological recommendations in psychiatry, with a particular focus on geriatric psychiatry.</p><p><strong>Method: </strong>A clinical pharmacologist, in collaboration with the attending psychiatrists and a consulting neurologist, conducted interdisciplinary medication reviews in a general psychiatric ward with a geropsychiatric focus at a university hospital over a 25-week period. All clinical and pharmacological recommendations were recorded and evaluated.</p><p><strong>Results: </strong>A total of 316 recommendations were made during 374 medication reviews. Indications/contraindications of drugs were the most frequently discussed topics (59/316; 18.7 %), followed by dose reductions (37/316; 11.7 %), and temporary or permanent discontinuation of medications (36/316; 11.4 %). The most frequent recommendations for dose reduction <b>involved</b>benzodiazepines (9/37; 24.3 %). An unclear or absent indication was the most common reason for recommending temporary or permanent discontinuation of the medication (6/36; 16.7 %).</p><p><strong>Conclusion: </strong>Interdisciplinary clinical pharmacologist-led medication reviews represented a valuable contribution to medication management in psychiatric patients, particularly the elderly ones.</p>","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":" ","pages":"393-405"},"PeriodicalIF":2.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11044510/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9847922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The association between psychological resilience and hair cortisol concentration in adults: A systematic review and meta-analysis.","authors":"LiWen Xiang, Xia Zeng, YinXia Luo, SuFang Tan, Fang Wang, XiaoRong Mao","doi":"10.1177/00912174231178108","DOIUrl":"10.1177/00912174231178108","url":null,"abstract":"<p><strong>Background: </strong>Resilience measures are typically based on subjective self-assessment, which is prone to bias. Objective biological/physiological measures of resilience are therefore needed. Hair cortisol concentration is a particularly promising candidate as a biomarker for resilience.</p><p><strong>Methods: </strong>We conducted a meta-analytic review from inception to April 2023 in PubMed, EMBASE, Cochrane Library, and Psych Info databases. All data were analyzed using a random-effects model.</p><p><strong>Results: </strong>Eight studies were identified that included a total of 1,064 adults. The random effects model demonstrated that resilience and hair cortisol concentration were inversely correlated (r = -0.18, 95% confidence interval [CI] = -0.27 to -0.09) with substantial heterogeneity (<i>I</i><sup>2</sup> = 54.2%, <i>p</i> = 0.03). The inverse association was stronger in those who were age 40 years or younger compared to those who were over 40 years. The correlation coefficients between psychological resilience and hair cortisol concentration among adults assessed by different resilience measures were r = -0.29 (95% CI = -0.49 to -0.08) for the CD-RISC-10; r = -0.21 (95% CI = -0.31 to -0.11) for the CDRISC- 25, and r = -0.08 (95% CI = -0.22 to 0.06) for the BRS. Six of eight studies examined the connection between resilience and perceived stress, where the weighted mean correlation coefficient was r = -0.45 (95% CI = -0.56 to -0.33), with considerable heterogeneity (<i>I</i><sup>2</sup> = 76.2%, <i>p</i> = 0.001).</p><p><strong>Conclusions: </strong>There is a negative association between psychological resilience and hair cortisol concentration based on these eight studies. Additional research, particularly prospective studies, is needed to determine whether hair cortisol concentration can be used as a biomarker for psychological resilience.</p>","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":" ","pages":"182-198"},"PeriodicalIF":2.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9503807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}