International Journal of Psychiatry in Medicine最新文献

{"title":"Cross-Disciplinary Cardiovascular and Psychiatric Recommendations: A Systematic Review of Clinical Guidelines.","authors":"Marina Delli Colli, Kyle T Greenway, Michael Goldfarb","doi":"10.1177/00912174251348996","DOIUrl":"10.1177/00912174251348996","url":null,"abstract":"<p><p>IntroductionIndividuals with serious mental illness (SMI), including major depression, schizophrenia, and bipolar disorder, experience disproportionately high rates of cardiovascular (CV) risk and disease. Despite this well-established connection, it remains unclear how professional society guidelines across cardiology and psychiatry address this relationship.MethodsMajor American and European CV and psychiatric society guidelines published from 2013-2023 were reviewed. Included were guidelines on primary and secondary CV disease prevention, and disease-specific guidelines for schizophrenia, bipolar disorder, and major depressive disorder. Relevant text was extracted and classified as recommendations or supporting text.ResultsTwenty-six guidelines were included (13 CV; 13 psychiatric). Psychiatric considerations appeared in 5 CV guidelines (38%), most commonly addressing mental illness treatment to improve CV outcomes (n = 5), pharmacological considerations (n = 2), and recognition of mental illness as a CV risk factor (n = 2). Only 13% of American CV guidelines included psychiatric content, compared to 80% of European CV guidelines. In contrast, 10 psychiatric guidelines (77%) included CV-related recommendations, including CV screening (n = 16), pharmacological considerations (n = 8), and risk factor control (n = 7). Among psychiatric guidelines, 40% of U.S. and 100% of European documents included CV content.ConclusionsCV considerations are more frequently addressed in psychiatric than psychiatric considerations in CV guidelines. European guidelines showed greater cross-disciplinary integration. These findings highlight the need for more unified, interdisciplinary guidance to reduce CV risk in individuals with SMI.</p>","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":" ","pages":"699-717"},"PeriodicalIF":1.9,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144287005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardiovascular Disease and Bipolar Disorder: A Review of Pathophysiology and Treatment Implications.","authors":"Mayuresh Chaudhari, Luis Mendez, Rene L Olvera, Sudha Seshadri, Antonio L Teixeira","doi":"10.1177/00912174251316947","DOIUrl":"10.1177/00912174251316947","url":null,"abstract":"<p><p>ObjectiveDespite the well-established increased risk of cardiovascular mortality in individuals with bipolar disorder (BD), prevention and treatment of cardiovascular risk factors and diseases have been largely overlooked in this population. This manuscript reviews the pathophysiological basis of the connection between BD and cardiovascular diseases, highlighting their shared mechanisms, reciprocal interactions, and relevant prevention and treatment strategies.MethodsFor this narrative review, a search was carried out on PubMed using the keywords bipolar disorder, cardiovascular diseases, and cardiovascular risk factors.ResultsThe increased frequency of cardiovascular morbidity in BD can be attributed to overlapping biological and psychosocial mechanisms. These mechanisms are complex and involve both direct effects of BD and indirect effects mediated by lifestyle and pharmacological factors. Cardiovascular diseases also significantly exacerbate the clinical course of BD and increase morbidity and healthcare costs; thus, their effective management can improve psychiatric outcomes and vice versa. However, patients with BD frequently encounter healthcare barriers.ConclusionAwareness initiatives and research on integrated care are needed to determine the best strategies for improving cardiovascular and psychiatric outcomes in individuals with BD.</p>","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":" ","pages":"718-735"},"PeriodicalIF":1.9,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13627774/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143030279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychiatric Issues in Cardiovascular Disease, Chronic Kidney Disease, Lung Cancer, and Neurological Disorders.","authors":"","doi":"10.1177/00912174261480941","DOIUrl":"10.1177/00912174261480941","url":null,"abstract":"","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":" ","pages":"695-698"},"PeriodicalIF":1.9,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148808868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychosocial Support Needs of Small Cell Lung Cancer Patients in China: A Qualitative Study From a Cultural Adaptation Perspective.","authors":"Li-Li Zhang, Lu Tian, Yan-Hua Teng, Ning Ma, Ya-Jing Yang","doi":"10.1177/00912174251368077","DOIUrl":"10.1177/00912174251368077","url":null,"abstract":"<p><p>ObjectiveThis qualitative study examined the psychosocial support needs of small cell lung cancer (SCLC) patients within China's family-oriented cultural context. Guided by cultural adaptation theory, the study explored how cultural values shape patients' psychological experiences and treatment decision-making.MethodsUsing a phenomenological purposive sampling strategy, 32 SCLC patients from a tertiary oncology hospital in Tianjin, China (May 2024-March 2025) participated in semi-structured, in-depth interviews. Transcripts were managed with NVivo 12, and themes were identified using Colaizzi's phenomenological analysis.ResultsDistinct cultural factors influenced patient needs. Six major themes emerged: (1) dual psychological crises stemming from disease stigma and prognostic dread; (2) pervasive insecurity due to recurrence uncertainty; (3) heightened decision-making stress and information asymmetry; (4) ethical and familial complexities in treatment choices-patients struggled to balance personal survival with family responsibilities and financial constraints; (5) an imbalance between the desire for professional psychological support and reliance on informal peer networks; and (6) deliberate suppression of negative emotions to maintain family stability.ConclusionsThe findings revealed a conflict between medical imperatives and entrenched family-oriented cultural values, underscoring the complexity of providing psychosocial support as part of SCLC care to Chinese patients.</p>","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":" ","pages":"785-798"},"PeriodicalIF":1.9,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144859790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Acupuncture at HT-7 (Shenmen) and GV-20 (Baihui) on Anxiety and Cardiovascular Functions in Generalized Anxiety Disorder: A Randomized Controlled Trial.","authors":"G Dhanushya Devi, A Mooventhan, L Nivethitha, A Vijay, N Mangaiarkarasi","doi":"10.1177/00912174251391031","DOIUrl":"10.1177/00912174251391031","url":null,"abstract":"<p><p>ObjectiveGeneralized anxiety disorder (GAD) is a condition that causes persistent and excessive worry, leading to physical and emotional symptoms. Acupuncture, a traditional Chinese medicine practice, has been studied as a potential treatment for anxiety disorders, including GAD. Though acupuncture at HT-7 and GV-20 along with other acupuncture points reduce anxiety level, no study to our knowledge has examined the effect of acupuncture at HT-7 and GV-20 alone on GAD. Therefore, the purpose of this study was to examine the effect of needling at HT-7 (Shenmen) and GV-20 (Baihui) acupuncture points on anxiety levels and cardiovascular function in patients with GAD.MethodsA total of 60 participants ages 20-55 diagnosed with GAD were randomly assigned to either a study group or a control group. The study group received acupuncture at the HT-7 and GV-20 points, while the control group underwent breath awareness meditation in supine position. Both groups underwent 20 min of the practice daily for 10 days. Assessments included Hamilton Anxiety Rating Scale (HAM-A) score, blood pressure (BP) and pulse rate (PR), which were performed before and after the intervention.ResultsParticipants in the study group experienced a significant reduction in anxiety levels (<i>P</i> < .001) compared to the control group. No significant inter-group differences were observed in systolic BP (<i>P</i> = .686), diastolic BP (<i>P</i> = .998), or PR (<i>P</i> = .925).ConclusionThe present study suggests that needling at HT-7 and GV-20 acupuncture points (20 min/session for 10 days) reduces anxiety levels without affecting cardiovascular function in younger and middle-aged patients with GAD.</p>","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":" ","pages":"752-763"},"PeriodicalIF":1.9,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145309827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Revisiting the Association between Levetiracetam and Psychiatric Symptoms in People With Epilepsy.","authors":"İbrahim Halil Deniz","doi":"10.1177/00912174261448998","DOIUrl":"10.1177/00912174261448998","url":null,"abstract":"<p><p>This letter-to-the-editor comments on the recent study by Gammoh et al examining the relationship between psychiatric symptoms and levetiracetam use in people with epilepsy. While the study addresses an important clinical issue, several methodological considerations may influence the interpretation of the findings. These include the limitations of the cross-sectional design, the lack of adjustment for baseline psychiatric history, and the reliance on self-reported screening instruments. In addition, the conclusion that levetiracetam is not associated with psychiatric symptoms should be interpreted cautiously in light of existing literature reporting heterogeneous but clinically relevant psychiatric adverse effects. Further longitudinal studies incorporating baseline psychiatric assessment are needed to better clarify this relationship.</p>","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":" ","pages":"813-815"},"PeriodicalIF":1.9,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147787926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Psychosocial Interventions on Depression in Chronic Kidney Disease: A Systematic Review and Meta-Analysis.","authors":"Jivitesh Singh Chahal, Sumit Saini, Priyanka Bansal, Jivesh Arora, Pir Dutt Bansal, Bhavneesh Saini","doi":"10.1177/00912174251326009","DOIUrl":"10.1177/00912174251326009","url":null,"abstract":"<p><p>BackgroundDepression is prevalent among individuals with chronic kidney disease (CKD) and those undergoing dialysis, with significant impacts on morbidity and mortality. This systematic review and meta-analysis was done to evaluate the efficacy of psychosocial interventions in managing depressive symptoms in patients with CKD.MethodsThis systematic review and meta-analysis adhered to PRISMA guidelines. A literature search was conducted across PubMed, Embase, Google Scholar, and Cochrane Library databases from January 2007 to July 2024. Randomized controlled trials (RCTs) investigating psychosocial interventions in CKD patients (Stage 4 or 5 or on hemodialysis) were included. The primary outcome was the change in depressive symptoms, measured by standardized clinical tools. Quality of life was a secondary outcome. Data extraction and bias assessment were conducted using ROB-2 and GRADEpro GDT tools.ResultsTwelve studies with a total of 792 participants (420 in the intervention group and 372 in the control group) were included. Cognitive-behavioral therapy (CBT) was the most common intervention. Psychosocial interventions significantly reduced depressive symptoms compared to routine care (mean difference [MD]: -4.22; 95% CI: -6.67, -1.76; <i>P</i> = 0.0008). High heterogeneity (I² = 89%) was noted. Sensitivity analysis confirmed the robustness of the results. The impact on quality of life was not statistically significant (MD: 0.94; 95% CI: -0.61, 2.49; <i>P</i> = 0.24).ConclusionsModerate-quality evidence suggests that psychosocial interventions effectively reduce depressive symptoms in CKD patients. While no significant improvement in quality of life was observed, these interventions provide an alternative to pharmacological treatments, potentially minimizing drug-related side effects.</p>","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":" ","pages":"764-784"},"PeriodicalIF":1.9,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143558047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Combined Psychological and Functional Exercise Interventions on Emotion, Life Quality, and Brain-Derived Neurotrophic Factor Levels in Patients With Parkinson's Disease: A Randomized Controlled Trial.","authors":"Tao Ding, Jing Zhang, Xue Jiang, Huayu Chen","doi":"10.1177/00912174261422307","DOIUrl":"10.1177/00912174261422307","url":null,"abstract":"<p><p>ObjectiveTo evaluate the effects of a combined psychological and functional exercise intervention on emotion, quality of life, and brain-derived neurotrophic factor (BDNF) levels in patients with Parkinson's disease (PD).MethodsIn this randomized controlled trial, 172 patients with PD were randomly assigned into 2 groups with 86 patients in each group. The control group received routine care, while the intervention group received a 12-week intervention combining psychological support with functional exercise in addition to routine care. Hamilton Anxiety Scale (HAMA), Hamilton Depression Scale (HAMD), Parkinson's Disease Questionnaire-39 (PDQ-39), Barthel Index, Movement Disorder Society-Unified Parkinson's Disease Rating Scale (MDS-UPDRS), and serum BDNF levels were assessed before and after the intervention. Adherence rates were also determined for each group. Spearman correlation was used to examine associations between changes in BDNF levels (ΔBDNF) and changes in HAMA (ΔHAMA) and HAMD (ΔHAMD) scores.ResultsAt the end of the 12-week clinical trial, the intervention group demonstrated significantly lower HAMA, HAMD, PDQ-39, and MDS-UPDRS scores (<i>P</i> < 0.001), and higher Barthel Index scores and BDNF levels compared to the control group. The adherence rate in the intervention group was higher than in the control group (90.70% vs 76.74%, respectively, <i>P</i> = 0.01).ConclusionA combined psychological and functional exercise intervention significantly improved emotional well-being, quality of life, daily functioning, treatment adherence, and BDNF levels (compared to the control group) in patients with PD. Based on these findings, this multi-component intervention may have value in treating PD patients.</p>","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":" ","pages":"799-812"},"PeriodicalIF":1.9,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146088055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Causal Association Between Atrial Fibrillation and Depression: Evidence From Mendelian Randomization Analyses.","authors":"ZhiFei Sun, XiaoDing Wang, QingHe Zhao, Li Xin, PingPing Zhao, XiaoQing Wang, DaCheng Liu","doi":"10.1177/00912174251393073","DOIUrl":"10.1177/00912174251393073","url":null,"abstract":"<p><p>BackgroundThis research assessed the causal influence of atrial fibrillation (AF) on depression.MethodsA two-sample Mendelian randomization (MR) approach was utilized along with data from additional databases. A genome-wide association study (GWAS) involving 463,010 participants allowed for the exploration of genetic variations associated with AF. Another GWAS with 215,644 individuals offered insights into the relationship between gene variants and depression. Data on the correlation between gene variants and depression were obtained from another GWAS encompassing 449,414 individuals. Effect sizes were assessed utilizing the inverse-variance weighted technique. Sensitivity analysis was conducted by weighted median, outlier, MR pleiotropy residual sum, weighted mode, and MR-Egger. A meta-analysis of the inverse-variance weighted (IVW) results from the two datasets was conducted.ResultsA significant association was found between genetically predicted AF and increased incidence of depression using 15 single nucleotide polymorphisms (SNPs) as markers. No evidence of gene pleiotropy was detected, as indicated by MR-Egger. Sensitivity analyses employing alternative Mendelian randomization techniques consistently yielded robust results. The combined odds ratio for depression was estimated at 29.19 (95% CI = 4.43-192.13, <i>P</i> < 0.001).ConclusionThis study found a causal relationship between genetically predicted AF and a heightened risk of depression.</p>","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":" ","pages":"736-751"},"PeriodicalIF":1.9,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146013243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy and Safety of Integrated Chinese and Western Medicine for Depression With Anxiety and Somatic Symptoms: A Meta-Analysis.","authors":"Yuhang Feng, Wenjie Liu","doi":"10.1177/00912174261494401","DOIUrl":"https://doi.org/10.1177/00912174261494401","url":null,"abstract":"<p><p>ObjectiveSomatic symptoms are often linked with depression and anxiety, making diagnosis difficult and limiting treatment effectiveness. Integrated Traditional Chinese and Western medicine has been studied as a complementary approach; however, its efficacy and safety have not been systematically evaluated. This review and meta-analysis examined the effectiveness and safety of integrated Traditional Chinese and Western medicine in patients diagnosed with depression with or without comorbid anxiety and somatic symptoms.MethodsThis systematic review and meta-analysis followed PRISMA 2020 guidelines. English-language studies published from 2014 to 2026 were searched in PubMed, Web of Science, and Scopus. Randomized controlled trials comparing integrated therapy with control interventions were included. The primary outcome was depression severity assessed by HAMD scores. Secondary outcomes included anxiety symptoms, somatic symptoms, and adverse events. A random-effects model was used, and heterogeneity was assessed using the I² statistic.ResultsEleven studies met review criteria. Integrated therapy significantly reduced depression severity compared with the standard Western medicine control condition (MD = -3.95, 95% CI: -4.71 to -3.19; I² = 59%). Anxiety symptoms were also significantly reduced (MD = -3.95, 95% CI: -4.65 to -3.26; I² = 50%). Somatic symptoms, including sleep disturbances and pain-related outcomes, improved but were assessed descriptively because of reporting variability. Adverse events were lower or similar in combined treatment groups, indicating a favorable safety profile. Funnel plot analysis suggested minimal publication bias.ConclusionIntegrated Traditional Chinese and Western medicine was associated with greater improvements in depression and anxiety symptoms than the included control interventions, which comprised Western medicine alone, placebo/sham interventions, or usual care, while showing generally good tolerability. However, given the methodological limitations, heterogeneity of comparator conditions, and low certainty of the available evidence, these findings should be interpreted cautiously.</p>","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":" ","pages":"912174261494401"},"PeriodicalIF":1.9,"publicationDate":"2026-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149217341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}