International Journal of Psychiatry in Medicine最新文献

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Vitamin B Intake and Post-stroke Depression: Results From the US National Health and Nutrition Examination Survey (NHANES) 2007-2018. 维生素B摄入量与中风后抑郁:2007-2018年美国国家健康与营养检查调查(NHANES)的结果
IF 1.3 4区 医学
International Journal of Psychiatry in Medicine Pub Date : 2025-09-16 DOI: 10.1177/00912174251376110
Mei Liu, Yanyu Sun, Jin Wu
{"title":"Vitamin B Intake and Post-stroke Depression: Results From the US National Health and Nutrition Examination Survey (NHANES) 2007-2018.","authors":"Mei Liu, Yanyu Sun, Jin Wu","doi":"10.1177/00912174251376110","DOIUrl":"https://doi.org/10.1177/00912174251376110","url":null,"abstract":"<p><p>ObjectivePost-stroke depression (PSD) is the most frequent psychiatric disorder after stroke, occurring in about 30% of stroke survivors. Little is known about the influence of dietary B-vitamin intake on PSD risk. This analysis examined the relationship between dietary B-vitamin intake and depression among stroke patients.MethodsA total of 1080 patients aged ≥20 years and having suffered a stroke participating in the 2007-2018 National Health and Nutritional Examination Surveys (NHANES) were included in this cross-sectional study. Depressive symptoms were evaluated using the 9-item Patient Health Questionnaire (PHQ-9). The association between dietary B vitamins intake and PSD was examined using multiple logistic regression analysis.ResultsAfter controlling for potential confounders (sex, age, race, BMI, family PIR, education level, marital status, history of disease, hypertension, hypercholesterolemia, diabetes, smoking, alcohol use and energy), significant inverse associations were found between dietary vitamin B1 (<i>P</i> = 0.002) and B6 (<i>P</i> = 0.002) intake and PHQ-9 scores. These association were significantly modified by unhealthy lifestyle factors and inflammation-related indicators.ConclusionsDietary vitamin B1 and B6 intake were inversely associated with PSD risk. The association between vitamin B1 or B6 and PSD was modified by unhealthy lifestyle factors and inflammation-related indicators. Future prospective studies are needed to determine the causal relationship between higher dietary vitamin B1 and B6 intake and a lower risk of PSD.</p>","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":" ","pages":"912174251376110"},"PeriodicalIF":1.3,"publicationDate":"2025-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145070725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Probable Autoimmune Encephalitis Presenting With Catatonia in a Young Woman: A Case Report and Review of the Literature. 可能的自身免疫性脑炎表现为紧张症在一个年轻女性:一个病例报告和文献复习。
IF 1.3 4区 医学
International Journal of Psychiatry in Medicine Pub Date : 2025-09-15 DOI: 10.1177/00912174251380668
Nancy M Gonzalez, Vishwa S Shah, Dafe Jessa, Reza Safavi
{"title":"Probable Autoimmune Encephalitis Presenting With Catatonia in a Young Woman: A Case Report and Review of the Literature.","authors":"Nancy M Gonzalez, Vishwa S Shah, Dafe Jessa, Reza Safavi","doi":"10.1177/00912174251380668","DOIUrl":"https://doi.org/10.1177/00912174251380668","url":null,"abstract":"<p><p>ObjectiveTo present a case of probable autoimmune encephalitis initially misdiagnosed as a primary psychiatric disorder.MethodA case of probable autoimmune encephalitis presenting with catatonia in a young woman 6 months post-partum is described in this article.ResultsThe patient was admitted to an outside hospital, diagnosed with a primary psychiatric condition, and sent to psychiatric inpatient, where she was denied admission due to labile hypertension. After admission to the medical service (and ICU), she responded to a lorazepam challenge, and made a complete recovery within several weeks after combination treatment with IV methylprednisolone, IV immunoglobulin (IVIG), and rituximab.ConclusionAutoimmune encephalitis should be suspected in patients presenting with labile vital signs, family history of autoimmunity, and new psychosis without prior history of psychiatric problems. Other important diagnostic considerations include neuroleptic malignant syndrome, substance-induced psychosis, or catatonia secondary to post-infectious immune-mediated encephalitis. While a first psychotic break should always be considered, the presence of autonomic instability, catatonia, seizures, or dyskinesias in a young woman postpartum should prompt a thorough medical and neurological work-up.</p>","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":" ","pages":"912174251380668"},"PeriodicalIF":1.3,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145066622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of Metabolic and Bariatric Surgery on Physical Outcomes, Mental Health, and Quality of Life Among Obese Patients in China. 代谢和减肥手术对中国肥胖患者生理结局、心理健康和生活质量的影响
IF 1.3 4区 医学
International Journal of Psychiatry in Medicine Pub Date : 2025-09-13 DOI: 10.1177/00912174251379911
Su Wang, Ling-Ling Zhou, Cui Liu
{"title":"Effects of Metabolic and Bariatric Surgery on Physical Outcomes, Mental Health, and Quality of Life Among Obese Patients in China.","authors":"Su Wang, Ling-Ling Zhou, Cui Liu","doi":"10.1177/00912174251379911","DOIUrl":"https://doi.org/10.1177/00912174251379911","url":null,"abstract":"<p><p>ObjectiveTo examine the effects of metabolic and bariatric surgery on physical outcomes, mental health, and quality of life (QOL) among obese patients in China.MethodsIncluded were 182 patients who underwent laparoscopic sleeve gastroplasty (LSG, a form of metabolic and bariatric surgery). Effects on postoperative weight, waist circumference, hip circumference, BMI, and the percentage of excess weight loss (%EWL) were observed during the 12 months after surgery. Changes in physical comorbidities were also determined. Anxiety symptoms were assessed by the Self-rated Anxiety Scale (SAS); depressive symptoms by the Self-rated Depression Scale (SDS); and QOL by the SF-36 scale. Assessment points were at baseline and 3, 6, and 12 months after surgery.ResultsSignificant improvements were observed in weight, waist circumference, hip circumference, BMI, and %EWL after surgery (<i>P</i> < 0.05). The remission rates for hypertension, diabetes, fatty liver, hyperlipidemia, and obstructive sleep apnea-hypopnea syndrome (OSAHS) were 89.5%, 95.5%, 82.6%, 81.7%, and 61.7%, respectively, 1 year after surgery (<i>P</i> < 0.05). Anxiety (SAS) and depressive (SDS) symptoms decreased significantly over time (<i>P</i> < 0.05). SF-36 scores in the physical and psychological domains increased significantly (<i>P</i> < 0.05). However, overall SF-36 scores were higher at 6 months compared to 12 months (<i>P</i> < 0.05).ConclusionLaparoscopic sleeve gastroplasty results in significant weight loss in the short term, which can improve anxiety symptoms, depressive symptoms, and QOL in obese patients. However, some social and psychological improvements appear to plateau at 6 months following surgery.</p>","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":" ","pages":"912174251379911"},"PeriodicalIF":1.3,"publicationDate":"2025-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145058738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
ADHD Comorbidity in Women With Depression and Anxiety: Prevalence, Clinical Features and Hyperfocus Dynamics. 患有抑郁和焦虑的女性ADHD合并症:患病率、临床特征和过度聚焦动力学。
IF 1.3 4区 医学
International Journal of Psychiatry in Medicine Pub Date : 2025-09-11 DOI: 10.1177/00912174251376111
Hazal Yavuzlar Civan, Tonguc Demir Berkol
{"title":"ADHD Comorbidity in Women With Depression and Anxiety: Prevalence, Clinical Features and Hyperfocus Dynamics.","authors":"Hazal Yavuzlar Civan, Tonguc Demir Berkol","doi":"10.1177/00912174251376111","DOIUrl":"https://doi.org/10.1177/00912174251376111","url":null,"abstract":"<p><p>ObjectiveThis study investigated ADHD comorbidity and clinical features, including hyperfocus, in women with depressive or anxiety disorders, addressing the diagnostic complexities arising from symptom overlap and the underdiagnosis of ADHD in this population.MethodsFemale patients from outpatient psychiatric clinics (n = 170) were assessed using the Beck Depression Inventory and Beck Anxiety Inventory. Participants meeting threshold scores underwent further evaluation with the Wender-Utah Rating Scale, Hyperfocus Scale, and Adult ADHD DSM-IV-Based Diagnostic Screening Scale, complemented by structured clinical interviews.ResultsADHD was identified in 19.6% (n = 33) of patients, 45.5% (n = 15) of whom were previously undiagnosed. ADHD was most prevalent in patients with social anxiety disorder (46.4%) and double depression (40.6%). In non-ADHD participants, attention deficit correlated positively with depression (r = 0.236, p = 0.005), hyperactivity with anxiety (r = 0.187, p = 0.029), and hyperfocus with ADHD scores (r = 0.434, p < 0.001; r = 0.292, p = 0.001); no such correlations were seen in the ADHD group.ConclusionADHD is common and frequently overlooked in women presenting with depression or anxiety. While hyperfocus is a relevant clinical feature, it is not diagnostic alone and correlates with ADHD symptoms in the absence of ADHD. Clinicians should conduct thorough screenings for ADHD and carefully interpret hyperfocus within the broader clinical context to ensure accurate diagnosis and timely, appropriate treatment.</p>","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":" ","pages":"912174251376111"},"PeriodicalIF":1.3,"publicationDate":"2025-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145042313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reduced pineal gland volume in patients with obsessive-compulsive disorder. 强迫症患者松果体体积减少。
IF 1.3 4区 医学
International Journal of Psychiatry in Medicine Pub Date : 2025-09-01 Epub Date: 2024-09-24 DOI: 10.1177/00912174241287996
Murad Atmaca, Sevler Yildiz, Muhammed Fatih Tabara, Mehmet Gurkan Gurok, Mustafa Yildirim, Hanefi Yildirim
{"title":"Reduced pineal gland volume in patients with obsessive-compulsive disorder.","authors":"Murad Atmaca, Sevler Yildiz, Muhammed Fatih Tabara, Mehmet Gurkan Gurok, Mustafa Yildirim, Hanefi Yildirim","doi":"10.1177/00912174241287996","DOIUrl":"10.1177/00912174241287996","url":null,"abstract":"<p><p>ObjectivePatients with obsessive-compulsive disorder (OCD) may have changes in their hypothalamic-pituitary-adrenal axis, and as a result, have increased secretion of adrenocorticotropic hormone and cortisol and reduced secretion of melatonin. Examination of pineal gland volumes in patients with OCD compared to healthy controls, thus, is an important consideration and the focus of this study.MethodsA total of 20 patients with OCD and 20 healthy controls were enrolled in this study. Demographic and clinical characteristics of participants were assessed, and structural magnetic resonance imaging was performed.ResultsPatients with OCD had a statistically significant smaller pineal gland volumes compared to healthy controls.ConclusionIn this pilot study, patients with OCD exhibited smaller pineal gland volumes compared to healthy control subjects. While this finding suggests a potential link between the pineal gland and OCD pathophysiology, further research with larger sample sizes and measurement of hormonal changes is necessary.</p>","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":" ","pages":"508-516"},"PeriodicalIF":1.3,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142331576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Post-stroke anxiety, pineal gland in OCD, insomnia, exercise and cognitive function, childhood trauma in functional seizures, detection of child mental health problems, and sources of mental health care in the congo: Treatments and epidemiology. 中风后焦虑,强迫症中的松果体,失眠,运动和认知功能,功能性癫痫发作中的儿童创伤,儿童精神健康问题的检测,以及刚果精神卫生保健的来源:治疗和流行病学。
IF 1.3 4区 医学
International Journal of Psychiatry in Medicine Pub Date : 2025-09-01 Epub Date: 2025-06-01 DOI: 10.1177/00912174251348970
Harold G Koenig
{"title":"Post-stroke anxiety, pineal gland in OCD, insomnia, exercise and cognitive function, childhood trauma in functional seizures, detection of child mental health problems, and sources of mental health care in the congo: Treatments and epidemiology.","authors":"Harold G Koenig","doi":"10.1177/00912174251348970","DOIUrl":"10.1177/00912174251348970","url":null,"abstract":"","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":" ","pages":"491-494"},"PeriodicalIF":1.3,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144200730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Associations between violent/sexual childhood trauma and maladaptive coping in patients with functional seizures. 儿童期暴力和性创伤与功能性癫痫患者适应不良之间的关系。
IF 1.3 4区 医学
International Journal of Psychiatry in Medicine Pub Date : 2025-09-01 Epub Date: 2025-01-11 DOI: 10.1177/00912174251314216
Randi H Libbon, Meagan Watson, Sunita Ramocan, Abbie Pennetti, Laura Strom, Zachary Giano
{"title":"Associations between violent/sexual childhood trauma and maladaptive coping in patients with functional seizures.","authors":"Randi H Libbon, Meagan Watson, Sunita Ramocan, Abbie Pennetti, Laura Strom, Zachary Giano","doi":"10.1177/00912174251314216","DOIUrl":"10.1177/00912174251314216","url":null,"abstract":"<p><p>ObjectiveFunctional seizures (FS) are a highly debilitating symptom of functional neurological disorder (FND). FS require a multi-disciplinary approach to treatment because the patient's initial presentation may be to neurology, emergency medicine, or primary care, and the treatment consists of psychotherapy. People with FS commonly experience severe childhood trauma, particularly sexual trauma. The present study examined associations between reported trauma and maladaptive coping mechanisms in the FS population.MethodsThis retrospective, observational study reports on 137 patients enrolled in the FS Clinic at the University of Colorado between March 2020 - March 2021. Linear regression was used to examine associations between self-reported childhood sexual and violent trauma and maladaptive coping mechanisms of self-blame and disengagement based on the Brief COPE. A quantile regression was generated for each of these outcomes.ResultsResults indicated that violent trauma and sexual trauma were reported by 47.5% and 61.6% of the sample, respectively. Of those exposed to violent trauma, 27.2% perceived it as extremely severe while 43.4% of those exposed to sexual trauma perceived it as extremely severe. Quantile regression for self-blame and disengagement showed significance for the 25th percentile of those who experienced violent trauma. Self-blame was significantly associated with the 50th and 75th percentile of those exposed to sexual trauma.ConclusionsThese findings supports the value of identifying trauma experienced by individuals with FS as it is associated with specific coping mechanisms that may affect treatment. Identifying prior trauma and current coping responses may assist in individualizing care for people with FS.</p>","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":" ","pages":"553-568"},"PeriodicalIF":1.3,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142967139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Heart rate during moderate exercise and cognitive function among adolescents: An experimental study. 适度运动时的心率与青少年的注意力:一项实验研究。
IF 1.3 4区 医学
International Journal of Psychiatry in Medicine Pub Date : 2025-09-01 Epub Date: 2024-12-18 DOI: 10.1177/00912174241309712
Krzysztof Janota, Bertrand Janota
{"title":"Heart rate during moderate exercise and cognitive function among adolescents: An experimental study.","authors":"Krzysztof Janota, Bertrand Janota","doi":"10.1177/00912174241309712","DOIUrl":"10.1177/00912174241309712","url":null,"abstract":"<p><p>ObjectiveExisting studies on the effects of physical activity on cognitive function have predominantly focused on pre- or post-exercise effects, leaving a gap in understanding with regard to immediate cognitive impacts during physical exertion. Understanding cognitive performance during activity could have significant implications for improving productivity and the development of therapeutic strategies.MethodsThis study examined the relationship between heart rate and cognitive performance, specifically attention, using the D2 attention test among 32 adolescents aged 12-18 years. Participants underwent attention assessments at rest and while moving at target heart rates of 100 bpm, 120 bpm, and 140 bpm. The influence of body mass index (BMI) and sleep quality on attention was also analyzed.ResultsA positive correlation between heart rate and attention was observed (r = 0.39, <i>P</i> < .005), indicating enhanced cognitive performance with increased heart rate. Furthermore, a negative correlation was found between BMI and attention (r = -0.37, <i>P</i> = .039) and a positive correlation was found between sleep quality and attention (r = 0.66, <i>P</i> = .014).ConclusionThese findings suggest that moderate physical activity can enhance attention, which could inform the design of educational, therapeutic, and occupational strategies. Future research should explore the generalizability of these findings across different cognitive domains, age group, and setting.</p>","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":" ","pages":"543-552"},"PeriodicalIF":1.3,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142848265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of chamomile oil inhalation on sleep quality in young adults with insomnia: A randomized controlled trial. 吸入洋甘菊精油对失眠症青少年睡眠质量的影响:随机对照试验
IF 1.3 4区 医学
International Journal of Psychiatry in Medicine Pub Date : 2025-09-01 Epub Date: 2024-11-15 DOI: 10.1177/00912174241301279
Y Deepa, A Vijay, L Nivethitha, G Nandhakumar, S Sathiya, A Mooventhan
{"title":"Effects of chamomile oil inhalation on sleep quality in young adults with insomnia: A randomized controlled trial.","authors":"Y Deepa, A Vijay, L Nivethitha, G Nandhakumar, S Sathiya, A Mooventhan","doi":"10.1177/00912174241301279","DOIUrl":"10.1177/00912174241301279","url":null,"abstract":"<p><p>ObjectiveInsomnia is characterized by difficulty falling asleep, staying sleep, or both. Aromatherapy is a commonly used complementary and alternative medicine practice by persons with insomnia. Previous studies have shown that use of chamomile oil during massage therapy improves the quality of sleep (QoS). However, to our knowledge, no randomized controlled trials have examined the effects of chamomile oil inhalation on the treatment of insomnia. The present study evaluated the effect of chamomile oil inhalation on QoS and insomnia severity in persons with insomnia.MethodsA total of 80 participants ages 18-35 with insomnia were randomly assigned to aromatherapy group (AG; n = 40) or a control group (CG; n = 40). Those in the AG group received chamomile oil inhalation, while those in the CG group engaged in their normal routine for 10 minutes a day, daily for 15 days. The Pittsburgh Sleep Quality Index (PSQI) and Insomnia Severity Index (ISI) were administered before and after the intervention.ResultsWithin-group analysis showed a significant reduction both in PSQI and ISI scores among those in the AG (<i>P</i> < 0.001 for both scores), whereas the CG reported a significant reduction in PSQI score (<i>P</i> = 0.033) and no significant changes in ISI score (<i>P</i> = 0.068). The between-group analysis after the intervention demonstrated a significant reduction in PSQI and ISI scores in the AG group (<i>P</i> < 0.001 for both) compared to the CG group. No participant in either group reported adverse events during or after the study.ConclusionFifteen days of chamomile oil inhalation before bedtime reduced insomnia severity and enhanced the quality of sleep for young adults suffering from insomnia. Further studies are needed to replicate the results of this study using an active control group.</p>","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":" ","pages":"533-542"},"PeriodicalIF":1.3,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142631861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of sertraline combined with psychological hotline-based Naikan therapy in the treatment of adolescents with depressive disorder. 舍曲林联合心理热线奈坎疗法治疗青少年抑郁症的疗效观察。
IF 1.3 4区 医学
International Journal of Psychiatry in Medicine Pub Date : 2025-09-01 Epub Date: 2025-04-21 DOI: 10.1177/00912174251337180
Ziming Zhang, Liping He, Panchun Dong, Yu Tian, Tairong Ai, Zhixuan Wang, Hongli Wang, Cheng Ma, Fuqiang Mao, Lijie Zhang
{"title":"Effect of sertraline combined with psychological hotline-based Naikan therapy in the treatment of adolescents with depressive disorder.","authors":"Ziming Zhang, Liping He, Panchun Dong, Yu Tian, Tairong Ai, Zhixuan Wang, Hongli Wang, Cheng Ma, Fuqiang Mao, Lijie Zhang","doi":"10.1177/00912174251337180","DOIUrl":"10.1177/00912174251337180","url":null,"abstract":"<p><p>ObjectiveThis study examined the effect of sertraline combined with psychological hotline-based Naikan therapy (a structured form of self-reflection) in the treatment of adolescents with depressive disorder. Hotline-based Naikan therapy is where telephone operators who have been trained in this form of therapy help address psychological distress for callers through telephone counselling.MethodsA randomized controlled trial was conducted involving 93 adolescent outpatients with depressive disorder, with 47 participants assigned to the combined group and 46 to the sertraline alone group. Adolescents in the combined group received treatment using sertraline at the same dose as those in the sertraline alone group. Depression and anxiety levels in both groups were evaluated using the Self-Rating Depression Scale (SDS) and Self-Rating Anxiety Scale (SAS) at baseline and after the 2nd, 4th and 12th week of treatment.ResultsThere were no significant differences between the groups at baseline in terms of demographic or clinical characteristics. Participants in both the combined and sertraline groups reported no serious adverse reactions. By the end of the 12th week of treatment, significant between-group differences were found on the SDS and the SAS scores, favoring the combined treatment group (χ<sup>2</sup> = 6.68, <i>P</i> = 0.010 and χ<sup>2</sup> = 5.68, <i>P</i> = 0.017, respectively).ConclusionSertraline combined with psychological hotline-based Naikan therapy is more effective in reducing depressive and anxiety symptoms in adolescents with depressive disorder than in those receiving sertraline alone.</p>","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":" ","pages":"517-532"},"PeriodicalIF":1.3,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144046072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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