Red kratom and red corvette: A case of mania induced by kratom withdrawal.

IF 1.1 4区医学 Q4 PSYCHIATRY

International Journal of Psychiatry in Medicine Pub Date : 2025-03-01 Epub Date: 2024-09-06 DOI:10.1177/00912174241281980

Mohammmad Abidali, Guitelle St Victor, Shady Mashaly, Pranab Dahal

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引用次数: 0

Abstract

Background: Kratom, derived from the Mitragyna speciose, a plant native to Southeast Asia, is a substance that is gaining popularity in the United States as a tool for self-medicating in opiate withdrawal and pain management. Its active compounds, mitragynine and 7-hydroxymitragynine, interact with various receptors in the body, resulting in a spectrum of clinical effects.

Case: A 56-year-old male with a history of depression and cannabis use disorder arrived at the emergency department in a state of severe agitation with erratic behavior and aggression. Further evaluation revealed a recent abrupt discontinuation of Kratom use. A psychiatric consultation was requested and performed by the consultation liaison team, diagnosing Kratom withdrawal as the most likely cause of his acute mania.

Conclusions: Neuropsychiatric symptoms arising from Kratom toxicity is a well-documented phenomenon. However, to our knowledge, this is the first documented case of acute mania induced by Kratom withdrawal.

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红色桔梗和红色雪佛兰一例由克来托戒断诱发的躁狂症。

背景：桔梗（Kratom）是从一种原产于东南亚的植物 Mitragyna speciose 中提取出来的，这种物质在美国越来越受欢迎，被用作戒断阿片类药物和止痛的自我治疗工具。它的活性化合物米曲盖宁（mitragynine）和 7-羟基米曲盖宁（7-hydroxymitragynine）与体内的各种受体相互作用，产生一系列临床效应：急诊科接诊了一名 56 岁的男性患者，他曾患有抑郁症和大麻使用障碍症，情绪严重躁动不安，行为古怪并具有攻击性。进一步评估显示，患者最近突然停止使用 Kratom。我们的会诊联络小组应患者要求进行了精神科会诊，诊断其急性躁狂症的最可能原因是 Kratom 戒断。Kratom 中毒引起的神经精神症状是一种有据可查的现象；然而，据我们所知，这可能是第一例有据可查的因 Kratom 戒断而诱发急性躁狂症的病例。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

International Journal of Psychiatry in Medicine 医学-精神病学

CiteScore

3.00

自引率

5.00%

发文量

审稿时长

6-12 weeks

期刊介绍： The International Journal of Psychiatry in Medicine (IJPM) bridges the gap between clinical psychiatry research and primary care clinical research. Providing a forum for addressing: The relevance of psychobiological, psychological, social, familial, religious, and cultural factors in the development and treatment of illness; the relationship of biomarkers to psychiatric symptoms and syndromes in primary care...