{"title":"Trends in the Prevalence of Osteoarthritis, Rheumatoid Arthritis, and Psoriatic Arthritis in U.S. Adults With Depression, 2005 to 2018.","authors":"Ji Yang, Jun Zhang","doi":"10.1177/00912174261435023","DOIUrl":"10.1177/00912174261435023","url":null,"abstract":"<p><p><b>Objective:</b> To investigate trends in osteoarthritis (OA), rheumatoid arthritis (RA), and psoriatic arthritis (PsA) among U.S. adults with depression from 2005 to 2018, and to evaluate their associations with demographic and metabolic factors. <b>Methods:</b> Cross-sectional data from seven cycles (2005-2018) of the National Health and Nutrition Examination Survey (NHANES) were analyzed. The study included 2068 adults with depression (PHQ-9 score ≥10) and 15 157 participants in total. Weighted prevalence trends were assessed using joinpoint regression, and propensity score weighting was applied to estimate arthritis risk. <b>Findings:</b> RA prevalence in depressed patients increased significantly from 7.8% (2005-2006) to 17.7% (2017-2018), making it the most prevalent type of arthritis. PsA prevalence declined sharply (from 7.2% to 1.7%), while the prevalence of OA remained stable (with a slight decrease from 11.7% to 10.7%). Depression was associated with a 40% higher risk of RA (OR = 1.40, 95% CI: 1.18-1.67) and a 44% higher risk of PsA (OR = 1.44, 95% CI: 1.13-1.85), but not with an increased risk of OA. RA prevalence was higher in women (18.9% vs 11.6% in men) and obese individuals (21.5% vs 11.1% in non-obese individuals). Racial disparities were observed, with non-Hispanic Black participants exhibiting the highest prevalence of RA (21.3%). <b>Conclusions:</b> The increasing burden of RA and PsA among depressed adults suggests shared inflammatory and metabolic mechanisms. Targeted screening in high-risk groups and integrated mental-metabolic care may improve early detection and longterm outcomes.</p>","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":" ","pages":"673-690"},"PeriodicalIF":1.9,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147460788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nirmit Shah, Edward Tran, Mohamed Aly, Vivian Phu, Ellie Laughlin, Monali S Malvankar-Mehta
{"title":"Depression and Anxiety in Patients With Irreversible Vision Loss: Meta-Analysis and Systematic Review.","authors":"Nirmit Shah, Edward Tran, Mohamed Aly, Vivian Phu, Ellie Laughlin, Monali S Malvankar-Mehta","doi":"10.1177/00912174251382653","DOIUrl":"10.1177/00912174251382653","url":null,"abstract":"<p><p>ObjectiveApproximately 295 million individuals globally live with moderate to severe irreversible vision loss, primarily due to conditions such as glaucoma, diabetic retinopathy, and age-related macular degeneration (AMD). Vision impairment diminishes quality of life leading to higher rates of depression and anxiety. This study investigated the prevalence of anxiety and depression in patients with irreversible vision loss, with a comparative analysis across the conditions of AMD, diabetic retinopathy, and glaucoma.MethodsA comprehensive literature search was conducted in Medline, Embase, CINAHL, and Cochrane databases, supplemented by manual searches of conference literature.ResultsThe prevalence of depression in patients with irreversible vision loss was found to be 21% (95% CI: 0.17-0.26) among 76 561 patients, with variations based on the cause: 27% (95% CI: 0.19-0.35) in AMD, 48% (95% CI: 0.32-0.64) in diabetic retinopathy, and 23% (95% CI: 0.16-0.29) in glaucoma. Anxiety prevalence was 22% (95% CI: 0.15-0.30) among 25 616 patients.ConclusionThe high prevalence of depression and anxiety underscores the need for comprehensive healthcare approaches that incorporate mental health support, including vision rehabilitation, psychotherapy, pharmacological interventions, and lifestyle modifications. Future research should explore factors that protect against anxiety and depression, as well as address the long-term effects of vision loss treatments on mental health outcomes.</p>","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":" ","pages":"574-602"},"PeriodicalIF":1.9,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13400842/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145253444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hayriye Dilek Hamurcu, Ahmet Kokurcan, Gülin Uçmak, Ali Çayköylü
{"title":"Anxiety, Depression, and Quality of Life Among Survivors of Differentiated Thyroid Cancer in Türkiye.","authors":"Hayriye Dilek Hamurcu, Ahmet Kokurcan, Gülin Uçmak, Ali Çayköylü","doi":"10.1177/00912174251413349","DOIUrl":"10.1177/00912174251413349","url":null,"abstract":"<p><p>ObjectiveDifferentiated thyroid cancer (DTC) is the most common endocrine malignancy. Despite excellent long-term survival, survivors often face an underrecognized psychosocial burden. This study examined how anxiety and depression relate to health-related quality of life (QoL) in DTC survivors, accounting for sociodemographic and clinical variables, to identify predictors of global health status and symptom burden.MethodIn this cross-sectional study, 518 biochemically stable DTC survivors (TSH 0.5-2.0 mIU/L) attending routine follow-up at a tertiary nuclear medicine clinic completed the Hospital Anxiety and Depression Scale (HADS) and the European Organisation for Research and Treatment of Cancer QoL Questionnaire-Core 30 (EORTC QLQ-C30).ResultsParticipants (mean age 46.6 ± 11.8 years; 86% female; mean time since diagnosis 6.8 ± 4.6 years) showed high rates of depression (51%) and anxiety (26%). Women had higher anxiety/depression and lower HRQoL than men. Those with depression had higher anxiety scores, lower global health/functioning, and higher overall symptoms (all <i>P</i> < .001). Anxiety showed broader, more consistent inverse associations with HRQoL than did depression. In multivariable linear regression, anxiety and depression were the strongest independent predictors of lower global health status and higher fatigue, whereas demographic (age, sex) and disease/treatment variables (time since diagnosis, number of radioactive iodine treatments) were not significant.ConclusionsPsychological distress-particularly anxiety-was more strongly associated with poorer HRQoL than disease/treatment indicators in DTC survivors. Routine psychosocial screening (eg, HADS), referral to psycho-oncology, targeted fatigue management, and gender-sensitive support should be integrated into endocrine follow-up to address this hidden survivor burden.</p>","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":" ","pages":"558-573"},"PeriodicalIF":1.9,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145851223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Psychological Distress and Major Adverse Cardiovascular Events in Post-PCI Acute Myocardial Infarction: Risk Profiling and Management Implications.","authors":"Lijun Sun, Yan Gao, Jing Wu, Lili Shao, Na Zheng","doi":"10.1177/00912174251364051","DOIUrl":"10.1177/00912174251364051","url":null,"abstract":"<p><p>ObjectiveThis study examined the correlation between psychological status and major adverse cardiovascular events (MACE) in acute myocardial infarction (AMI) patients after percutaneous coronary intervention (PCI).MethodsA retrospective analysis was conducted in 200 AMI patients who underwent PCI between January 2020 and December 2023 at a tertiary care hospital in China. The incidence of MACE was calculated, and the correlation between Hospital Anxiety and Depression Scale (HADS) scores and MACE was determined.ResultsThree-quarters (75.0%) of patients scored above the threshold on significant anxiety (HADS-A >9) and 61.0% did so for depressive symptoms (HADS-D >9) post-PCI. Multivariate analysis identified higher education (OR = 1.75, 95% CI = 1.08-2.85), lower income (OR = 0.23, 95% CI = 0.09-0.59), and smoking (OR = 0.38, 95% CI = 0.16-0.93) as independent risk factors for anxiety, while low income (OR = 0.24, 95% CI = 0.11-0.53), smoking (OR = 5.13, 95% CI = 2.21-11.87), and female gender (OR = 3.04, 95% CI = 0.26-7.35) were significantly associated with depression (<i>P</i> < 0.05). MACE occurred in 21.5% of patients. First-time PCI (OR = 0.03, 95% CI = 0.03-0.30) and depression scores were significantly associated with increased MACE risk (r = 0.21, OR = 47.80, 95% CI = 8.38-27.47, <i>P</i> < 0.05), whereas anxiety scores showed no significant association (<i>P</i> > 0.05).ConclusionAnxiety and depression are common post-PCI symptoms in AMI patients, and depressive symptoms are significantly correlated with disease progression (MACE scores). Greater focus on patients' mental health, may help improve the prognosis of AMI patients after PCI.</p>","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":" ","pages":"615-630"},"PeriodicalIF":1.9,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144754973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shiva Zamani, Mohammadreza Abed, Ali Amini, Atiye Ghorbanpour
{"title":"Examining the General Health and Mental Health of Individuals With Iron-Deficiency Anemia.","authors":"Shiva Zamani, Mohammadreza Abed, Ali Amini, Atiye Ghorbanpour","doi":"10.1177/00912174251382660","DOIUrl":"10.1177/00912174251382660","url":null,"abstract":"<p><p>ObjectiveIron deficiency anemia is one of the most common nutritional disorders in the world, particularly among women and children. This condition, caused by insufficient iron levels in the body, not only affects physical performance and reduces energy but can also have a significant impact on mental health. This study compared the general health and mental health of individuals with iron deficiency anemia with that of healthy individuals.MethodHealthy individuals and those with iron deficiency anemia were assessed at the Aramesh Pathobiology and Genetics Laboratory in Tehran, Iran. Participants were a convenience sample of 170 healthy individuals and 170 individuals with iron deficiency anemia. Data were collected using the General Health Questionnaire and the Irritability Questionnaire.ResultsIndividuals with iron deficiency anemia scored higher than healthy individuals on somatic symptoms, anxiety and insomnia, social dysfunction, and depression. Irritability was also significantly higher in this group, indicating a possible negative impact of iron deficiency anemia on emotional regulation. Furthermore, irritability and social dysfunction strongly predicted iron deficiency anemia.ConclusionIron deficiency anemia increases the risk of symptoms of mental disorder, including depression, anxiety, irritability, insomnia, social dysfunction, as well as symptoms of physical health problems.</p>","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":" ","pages":"631-649"},"PeriodicalIF":1.9,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145226216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Depression and Anxiety Symptoms in Acute and Chronic Medical Illness.","authors":"","doi":"10.1177/00912174261460277","DOIUrl":"10.1177/00912174261460277","url":null,"abstract":"","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":" ","pages":"535-538"},"PeriodicalIF":1.9,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148165338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Harun Yetkin, Mehmet Fatih Uzanulu, Onur Selçuk Yiğit, Zeynep Dilara Yetkin, İrem Dikilitaş, Hacı Mehmet Çitil, Hacı Bayram Berktaş, Mehtap Karaaslan
{"title":"Sleep Quality, Daytime Sleepiness, and Circadian Rhythm Characteristics in Chronic Kidney Disease: A Cross-Sectional Study Across Disease Stages.","authors":"Harun Yetkin, Mehmet Fatih Uzanulu, Onur Selçuk Yiğit, Zeynep Dilara Yetkin, İrem Dikilitaş, Hacı Mehmet Çitil, Hacı Bayram Berktaş, Mehtap Karaaslan","doi":"10.1177/00912174261485675","DOIUrl":"https://doi.org/10.1177/00912174261485675","url":null,"abstract":"<p><p>ObjectiveTo compare sleep quality, daytime sleepiness, and circadian rhythm characteristics across clinically defined chronic kidney disease (CKD) groups and to examine their relative contribution to global subjective sleep quality.MethodThis two-center, cross-sectional study enrolled 344 adults with CKD (response rate: 96.6%) from nephrology settings in Turkey. Participants were classified into three groups: mild-to-moderate CKD (KDIGO stages 2-3; n = 133), advanced CKD without dialysis (stages 4-5; n = 37), and dialysis-dependent CKD (stage 5D; n = 174). Sleep quality, daytime sleepiness, and circadian rhythm parameters were assessed using the Pittsburgh Sleep Quality Index (PSQI), Epworth Sleepiness Scale (ESS), and Munich Chronotype Questionnaire (MCTQ). Hierarchical regression identified predictors of PSQI global scores.ResultsESS total scores were significantly higher in the dialysis-dependent group compared with both other groups (ε<sup>2</sup> = 0.182, the only large effect size), whereas PSQI global scores were paradoxically lower in this group (adjusted <i>P</i> = 0.021). Biological chronotype (MSFsc) did not differ across groups. In hierarchical regression, ESS (β = 0.525) and dialysis-dependent status (β = -0.318) were the only significant predictors of PSQI global scores, with sleep-wake variables adding 24.3% explained variance beyond demographic and clinical factors.ConclusionsCKD-related sleep-wake burden is more prominently reflected in daytime sleepiness and social-circadian disorganization than in global subjective sleep quality. Assessment of daytime sleepiness may improve recognition of sleep-wake dysregulation in nephrology settings.</p>","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":" ","pages":"912174261485675"},"PeriodicalIF":1.9,"publicationDate":"2026-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148867785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chaitali Dagli, Charity J Morgan, Lori L Davis, Chen Lin
{"title":"Feasibility, Safety, and Exploratory Outcomes of Methylphenidate for Posttraumatic Stress Disorder Among Patients With Ischemic Stroke.","authors":"Chaitali Dagli, Charity J Morgan, Lori L Davis, Chen Lin","doi":"10.1177/00912174261480441","DOIUrl":"10.1177/00912174261480441","url":null,"abstract":"<p><p>ObjectivePosttraumatic stress disorder (PTSD) is prevalent among veterans and is associated with increased stroke risk. This study examined the feasibility, safety, and preliminary efficacy of methylphenidate (MPH) for reducing PTSD symptom severity and improving functional outcomes among veterans with pre-existing PTSD recovering from stroke.MethodsA randomized, double-blind, placebo-controlled phase 2 pilot trial was conducted at a Veterans Affairs medical center. Veterans aged 40-75 years with ischemic stroke and pre-existing PTSD were randomized 1:1 to receive MPH or placebo for 12 weeks followed by a 2-week taper. The outcomes included clinician-rated PTSD symptom severity using the Clinician-Administered PTSD Scale for DSM-5 (CAPS-5), self-reported PTSD symptoms with the PTSD Checklist for DSM-5 (PCL-5), global functional disability via the modified Rankin Scale (mRS), and stroke-related quality of life and function measured by the Stroke Impact Scale-16 (SIS-16). Between-group differences in change scores were evaluated using two-sample tests.ResultsTwenty veterans were enrolled (mean age 63.7 years; 95% male). Baseline characteristics were similar between treatment groups. CAPS-5 and PCL-5 scores decreased over time in both groups, with no significant between-group differences, although greater reductions were observed in the MPH group at multiple time points. Both groups demonstrated modest improvements in functional outcomes, with trends toward greater gains in cognitive and participation-related domains among participants receiving MPH. MPH was generally well tolerated, with no unexpected safety concerns observed.ConclusionMPH was feasible and generally well tolerated. Exploratory analyses suggested possible improvements in selected cognitive and recovery-related domains that warrant confirmation in adequately powered studies.</p>","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":" ","pages":"912174261480441"},"PeriodicalIF":1.9,"publicationDate":"2026-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13664527/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148814771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Post-Traumatic Stress Disorder in Military Personnel: A Comparative Analysis of Rehabilitation Strategies in the Ukraine.","authors":"Inna Osadchenko, Nina Tverezovska, Iryna Demchenko, Oleksandra Drachuk, Nataliia Hrynova","doi":"10.1177/00912174261482023","DOIUrl":"https://doi.org/10.1177/00912174261482023","url":null,"abstract":"<p><p>ObjectiveThe psychological rehabilitation of military personnel with post-traumatic stress disorder (PTSD) gained critical importance during the armed conflict in Ukraine (2022-2026). This study compared the effectiveness of alternative approaches to PTSD rehabilitation for Ukrainian soldiers and provides recommendations for optimizing psychological assistance.MethodsA longitudinal study was conducted with 512 Ukrainian service members with clinically significant PTSD who received support in state rehabilitation centres and private psychological programs between 2022 and 2025. Participants were non-randomly divided into 3 groups: an experimental group (n = 204) receiving a comprehensive program, a group (n = 188) following a standardized international protocol, and a control group (n = 120), based on practical constraints related to the availability of specialized rehabilitation programs. PTSD symptoms were assessed before and after the interventions using the PCL-5.ResultsThose participating in the comprehensive program achieved the most significant reduction in PTSD symptoms, from 51.2 to 28.5 points on the PCL-5 scale (44.3% reduction), compared to a 36.3% reduction in the international protocol group and 5.4% in the control group. Additionally, the comprehensive program showed a 50.2% reduction in depressive symptoms, a 49.2% decrease in anxiety, and an 89.8% improvement in quality of life. The greatest impact was on avoidance symptoms, which decreased by 61.5%, linked to art therapy integrated into cognitive behavioural therapy.ConclusionThese results emphasize the need for a national clinical protocol for comprehensive PTSD rehabilitation and the training of specialists in trauma-informed care to support military personnel in the Ukraine.</p>","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":" ","pages":"912174261482023"},"PeriodicalIF":1.9,"publicationDate":"2026-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148819943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Response to Letter to the Editor: Decreased Risk of Mental Illness Worsening: Comment on \"Glucagon-like Peptide-1 Receptor Agonists in Individuals With Severe Mental Illness: A Systematic Review and Meta-Analysis of Randomized Controlled Trials\".","authors":"Manit Srisurapanont, Sirijit Suttajit, Benchalak Maneeton","doi":"10.1177/00912174261480243","DOIUrl":"https://doi.org/10.1177/00912174261480243","url":null,"abstract":"","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":" ","pages":"912174261480243"},"PeriodicalIF":1.9,"publicationDate":"2026-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148809184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}