International Journal of Psychiatry in Medicine最新文献

{"title":"Letter to the Editor; Regarding the Effects of Electroconvulsive Therapy on Optic Nerve Sheath Diameter, as a Proxy for Intracranial Pressure.","authors":"Rutger V A Hollestelle, Jochem K H Spoor, Iscander M Maissan, Maxine Dibué","doi":"10.1177/00912174251365490","DOIUrl":"https://doi.org/10.1177/00912174251365490","url":null,"abstract":"","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":" ","pages":"912174251365490"},"PeriodicalIF":1.3,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144762186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychological Distress and Major Adverse Cardiovascular Events in Post-PCI Acute Myocardial Infarction: Risk Profiling and Management Implications.","authors":"Lijun Sun, Yan Gao, Jing Wu, Lili Shao, Na Zheng","doi":"10.1177/00912174251364051","DOIUrl":"https://doi.org/10.1177/00912174251364051","url":null,"abstract":"<p><p>ObjectiveThis study examined the correlation between psychological status and major adverse cardiovascular events (MACE) in acute myocardial infarction (AMI) patients after percutaneous coronary intervention (PCI). Based on these results, health management strategies were discussed.MethodsA retrospective analysis was conducted in 200 AMI patients who underwent PCI between January 2020 and December 2023 at a tertiary care hospital in China. The incidence of MACE was calculated, and the correlation between Hospital Anxiety and Depression Scale (HADS) scores and MACE was determined.ResultsThree-quarters (75.0%) of patients scored above the threshold on significant anxiety (HADS-A >9) and 61.0% did so for depressive symptoms (HADS-D >9) post-PCI. Multivariate analysis identified higher education (OR: 1.754, 95% CI: 1.080∼2.851), lower income (OR: 0.229, 95% CI: 0.089∼0.589), and smoking (OR: 0.384, 95% CI: 0.159∼0.931) as independent risk factors for anxiety, while low income (OR: 0.236, 95% CI: 0.105∼0.529), smoking (OR: 5.125, 95% CI: 2.213∼11.867), and female gender (OR: 3.042, 95% CI: 0.260∼7.348) were significantly associated with depression (<i>P</i> < 0.05). MACE occurred in 21.5% of patients. First-time PCI (OR: 0.03, 95% CI: 0.003∼0.296) and depression scores were significantly associated with increased MACE risk (r = 0.207, OR: 47.79, 95% CI: 8.38∼272.47, <i>P</i> < 0.05), whereas anxiety scores showed no significant association (<i>P</i> > 0.05).ConclusionAnxiety and depression are common post-PCI symptoms in AMI patients, and depressive symptoms are significantly correlated with disease progression (MACE scores). Greater focus on patients' mental health, may help improve the prognosis of AMI patients after PCI.</p>","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":" ","pages":"912174251364051"},"PeriodicalIF":1.3,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144754973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors influencing the psychological health of pregnant women in advanced maternal age (AMA) during the peripartum period in China.","authors":"Jin Song, Zi-Long Ma, Hui-Shi Zhang, Ting Liang, Xiwen Zhang, Autumn Wang","doi":"10.1177/00912174251360100","DOIUrl":"https://doi.org/10.1177/00912174251360100","url":null,"abstract":"<p><p><b>Objective:</b> The age of childbirth for women has been significantly delayed in recent times, leading to an increase in the proportion of pregnant women in advanced maternal age (AMA). Due to increased physiological challenges and higher incidence of pregnancy complications, advanced maternal age women often face greater mental stress, including familial and societal pressures associated with latter-age childbirth. In order to investigate the psychological health of AMA pregnant women during the later stages of pregnancy and peripartum period and identify psychosocial predictors of mental health, we conducted a cross-sectional study on this issue.<b>Methods:</b> Selected primiparous women were assessed at three time points (at the 8th month prenatal examination, the day of delivery and 42 days postpartum). There were 125 eligible pregnant women for enrollment at each time points. Sociodemographic characteristics, psychological concerns, and mental health were measured at these timepoints.<b>Results:</b> The incidence of psychological distress among older peripartum women was significantly higher than among younger women. Increased psychological stress was correlated with concerns about maternal and infant health, fear of labor pain, apprehension regarding personal career development, and worries about family support and financial conditions.<b>Conclusions:</b> The mental health status of older peripartum women is concerning, suggesting the need for psychological support by primary care physicians and other healthcare providers.</p>","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":" ","pages":"912174251360100"},"PeriodicalIF":1.3,"publicationDate":"2025-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144745872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors associated with caregiver burden among family members of persons with schizophrenia in urban communities of China.","authors":"Fangling Liang, Hui Du, Xin Liu, Mengyao Zheng, Changjiu He","doi":"10.1177/00912174241292702","DOIUrl":"10.1177/00912174241292702","url":null,"abstract":"<p><p>ObjectiveFamily members bear a heavy burden when caring for those with schizophrenia. The present study examined the degree of caregiver burden and characteristics related to it among family caregivers of persons with schizophrenia in Chinese urban settings.MethodsBetween August 2023 and June 2024, a cross-sectional study was conducted involving 401 family caregivers of persons with schizophrenia living in metropolitan settings. The following measures were administered: the Zarit Burden interview (ZBI), General Self-Efficacy Scale (GSES), Social Support Rating Scale (SSRS), and Simplified Coping Style Questionnaire (SCSQ). Linear regression analyses were used to identify independent correlates of caregiver burden.ResultsFamily caregivers of persons with schizophrenia had an average ZBI score of 32.90(SD = 17.53) on a 0-88 scale, with the majority (80.0%) reporting moderate caregiver burden (scores of 21-39). Independent correlates of caregiver burden were the person with schizophrenia's marital status (not married), impulsive or aggressive conduct in the previous year, the caregiver's physical health (poor), and not having multiple caregivers.ConclusionsFamily caregivers of persons with schizophrenia experience a moderate level of caregiver burden. To lessen the psychological suffering of and strain on caregivers, it is important to intervene early on impulsive and aggressive conduct of persons with schizophrenia, effectively treat physical health problems of caregivers, and provide support and practical assistance to those caring for persons with schizophrenia.</p>","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":" ","pages":"378-394"},"PeriodicalIF":1.1,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142479628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors related to the treatment of patients with schizophrenia and other mental health problems in the setting of medical illness.","authors":"Harold G Koenig","doi":"10.1177/00912174251338094","DOIUrl":"10.1177/00912174251338094","url":null,"abstract":"","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":" ","pages":"359-362"},"PeriodicalIF":1.1,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144042397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Peripheral immune cell markers and cognitive function in patients with schizophrenia.","authors":"Aykut Karahan, Işılay Manzak Saka, Demet Sağlam Aykut, Filiz Civil Arslan, Ezgi Selçuk Özmen, Evrim Özkorumak Karagüzel","doi":"10.1177/00912174241266059","DOIUrl":"10.1177/00912174241266059","url":null,"abstract":"<p><p>ObjectivesThe purpose of this study was to investigate the relationship between peripheral immune cell markers and cognitive function in patients with schizophrenia and healthy controls.MethodsThirty-five patients diagnosed with schizophrenia with a stable course and a control group of 35 individuals matched by sex, education, and age were included in this cross-sectional study. The Wisconsin Card Sorting Test (WCST), the Rey Auditory Verbal Learning Test (RAVLT), and the Stroop Test were used for neuropsychological evaluation. Blood neutrophil and lymphocyte percentages, neutrophil-lymphocyte ratio (NLR), and systemic immune-inflammation index (SII) values were calculated.ResultsThe female patients exhibited significantly higher NLR and neutrophil percentages than the female controls. They also demonstrated higher NLR, neutrophil percentage, and SII when compared to male patients. The increased neutrophil percentages and NLR and decreased lymphocyte percentages in the female patients were significantly correlated with worsening Stroop interference and RAVLT 1 scores. Additionally, a longer duration of illness was significantly correlated with elevated NLR, SII, and neutrophil percentage, and decreased lymphocyte percentage. A higher number of previous hospitalizations was correlated with elevated SII and decreased lymphocyte percentage. Regression analysis showed a significant association between neutrophil percentage and Stroop interference scores used to evaluate attentional functions in patients with schizophrenia.ConclusionsThese results suggest that gender and course of illness may affect NLR and SII values. An elevated neutrophil percentage may be one of the factors affecting attentional dysfunction in patients with schizophrenia. Prospective studies are now needed to verify these findings.</p>","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":" ","pages":"405-419"},"PeriodicalIF":1.1,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141731612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Depressive symptoms, all-cause mortality, and cardiovascular-specific mortality among adults with different diabetic status in the United States.","authors":"Hua-Zhao Xu, Xiang-Da Meng, Qian Liu, Yu-Jun Xiong","doi":"10.1177/00912174241303099","DOIUrl":"10.1177/00912174241303099","url":null,"abstract":"<p><p>ObjectiveThe relationship between diabetes, depressive symptoms, and mortality is well established. However, the effect of depressive symptoms on mortality among people with prediabetes remains unclear. This study examined the effects of depressive symptoms on mortality across different diabetic statuses.MethodsData were analyzed from cross-sectional samples collected as part of the National Health and Nutrition Examination Survey (NHANES) from 1999 to 2018, with a final sample size of 36,246 participants. Mortality status and cause of death were prospectively determined by cross-referencing records with the publicly accessible National Death Index through 2019. Kaplan-Meier survival curves and Cox regression analysis were utilized to assess the relationship between depressive symptoms and mortality across different diabetic statuses from nondiabetic to prediabetic to diabetic.ResultsIn the non-diabetic group, no effect of depression severity on all-cause mortality or cardiovascular mortality was found in the final models. In the prediabetic group, however, the hazard ratios were increased for both mild depressive symptoms (HR = 1.35, 95% CI = 1.14-1.60) and moderate-to-severe depressive symptoms (HR = 1.65, 95% CI = 1.31-2.08). In the diabetic group, surprisingly, the all-cause mortality risk was somewhat lower than in the pre-diabetic group (HR = 1.28, 95% CI = 1.08-1.51 for mild and HR = 1.29, 95% CI = 1.06-1.56 for moderate-to-severe depressive symptoms). Similar patterns were noted for cardiovascular mortality, where risk of moderate-severe depressive symptoms was even greater in the prediabetic group (HR = 1.83, 95% CI = 1.18-2.85) than in the diabetic group.ConclusionIn this prospective cohort study of a nationally representative sample of U.S. adults, a positive association was found between depressive symptoms and mortality across different diabetic statuses. These findings highlight the importance of evaluating depressive symptoms across the glycemic spectrum, especially among individuals with prediabetes.</p>","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":" ","pages":"468-488"},"PeriodicalIF":1.1,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142693516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of six antipsychotic drug treatment regimens on short-term heart rate variability in patients with schizophrenia.","authors":"Lifen Huang, Chaoyang Wei, Qinghua Qin","doi":"10.1177/00912174241293650","DOIUrl":"10.1177/00912174241293650","url":null,"abstract":"<p><p>ObjectiveMany antipsychotic drugs have cardiac side effects. Heart rate variability (HRV) analysis can be used as a indicator of cardiotoxicity in cases where a decrease in HRV occurs after the administration of antipsychotics such as clozapine. The purpose of this study was to explore the effects of 6 antipsychotic drug regimens on short-term HRV in patients with schizophrenia.MethodsData from 164 patients with schizophrenia between January 2018 and June 2023 were retrospectively analyzed. Based on the drug used for treatment, patients were categorized into clozapine combination (clozapine combined with aripiprazole, risperidone or ziprasidone), clozapine alone, olanzapine, aripiprazole, ziprasidone, and risperidone groups. Heart rate variability indices were calculated using time domain analysis, including the standard deviation of the RR intervals (SDNN), the root mean square of successive RR interval differences (RMSSD), and the percentage of successive RR intervals over 50 ms (PNN50).ResultsCompared with the pretreatment period, the SDNN, RMSSD, and PNN50 were significantly lower in the clozapine combination, clozapine, olanzapine and aripiprazole groups at the end of weeks 2 and 4 of treatment (<i>P</i> < 0.05). However, those indicators in ziprasidone and risperidone groups did not show this decrease (<i>P</i> > 0.05).ConclusionThe effects of clozapine combination and clozapine on HRV were greater than for olanzapine, aripiprazole, ziprasidone, or risperidone. Attention should be paid to controlling the dose of clozapine combination and clozapine alone and monitoring the patient's electrocardiogram during administration.</p>","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":" ","pages":"363-377"},"PeriodicalIF":1.1,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142512221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of uremic toxins and systemic inflammation with depression and anxiety among hemodialysis patients in Montenegro.","authors":"Batric Babovic, Natasa Belada Babovic, Filip Tomovic, Snezana Radovanovic, Mladen Debeljevic, Jelena Djordjevic, Olgica Mihaljevic","doi":"10.1177/00912174241298837","DOIUrl":"10.1177/00912174241298837","url":null,"abstract":"<p><p>ObjectiveThe purpose of this study was to examine the association between uremic toxins, inflammation, depression and anxiety among hemodialysis patients in Montenegro.MethodThe cross-sectional study included 88 patients undergoing hemodialysis. Depression symptoms were assessed by Patient Health Questionnaire (PHQ-9), and anxiety symptoms were measured by the Beck Anxiety Inventory (BAI). Standard laboratory methods were used to measure uremic toxins and systemic inflammation (C-reactive protein, Neutrophil-to-Lymphocyte Ratio [NLR] and Platelet-to-Lymphocyte Ratio [PLR]).ResultsClinically significant depression (PHQ-9 ≥ 10) and anxiety (BAI ≥16) were found in 55.7% and 27.2%, respectively. Logistic regression analyses revealed that serum urea, beta 2-microglobulin (B2M), and systemic inflammation (CRP, NLR, PLR) were significantly and independently associated with depressive symptoms, whereas serum urea, creatinine, uric acid, B2M, and systemic inflammation (CRP nad NLR) were associated with anxiety symptoms.ConclusionsDepressive symptoms and anxiety are common among hemodialysis patients in Montenegro, and are associated with increased levels of systematic inflammation, serum urea, and beta 2-microglobulin.</p>","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":" ","pages":"443-455"},"PeriodicalIF":1.1,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142584885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of cognitive behavioral therapy in relieving tinnitus.","authors":"Fatih Bal","doi":"10.1177/00912174241272674","DOIUrl":"10.1177/00912174241272674","url":null,"abstract":"<p><p>ObjectiveThis study examined the effects of Cognitive Behavioral Therapy (CBT) on tinnitus in individuals aged 18-60 years.MethodsThirty participants with subjective tinnitus for at least six months were included in a randomized controlled trial. Randomized were 15 participants in the experimental group and 15 in the control group, with pre-test and post-test measurements. The experimental group received eight CBT sessions over eight weeks. Data were collected using Tinnitus Handicap Inventory (THI) and Visual Analog Scale (VAS). The Mann-Whitney and Wilcoxon Signed Rank Test were used to compare scores between experimental and control groups at baseline and after the intervention.ResultsA within-group difference was found between total scores on THI and VAS before and after CBT in the experimental (z = -3.241, <i>P</i> = 0.001), but not in the control group (z = -1.764, <i>P</i> = 0.078). Following the intervention, there was a significant between-group difference on the THI Emotional, Catastrophic, and Functional tinnitus subscale scores, favoring the experimental group.ConclusionsCBT significantly reduced tinnitus level, severity, duration, frequency, discomfort, tinnitus-related attention deficit, and sleep problems. Further studies are needed to replicate these findings in larger samples and other populations.</p>","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":" ","pages":"420-442"},"PeriodicalIF":1.1,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141996809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}