INTERNATIONAL JOURNAL OF MEDICAL SCIENCE AND CLINICAL RESEARCH STUDIES最新文献

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The Systematic Construction of Emergency Medical Security System in Long-Distance Walking Movement on Urban Paved Roads 城市铺装道路长途步行运动中紧急医疗保障系统的系统构建
INTERNATIONAL JOURNAL OF MEDICAL SCIENCE AND CLINICAL RESEARCH STUDIES Pub Date : 2024-03-16 DOI: 10.47191/ijmscrs/v4-i03-18
Dong Jing, Yang Zheng, Jialong Ruan, Jianing Chen, Xiaohong Song
{"title":"The Systematic Construction of Emergency Medical Security System in Long-Distance Walking Movement on Urban Paved Roads","authors":"Dong Jing, Yang Zheng, Jialong Ruan, Jianing Chen, Xiaohong Song","doi":"10.47191/ijmscrs/v4-i03-18","DOIUrl":"https://doi.org/10.47191/ijmscrs/v4-i03-18","url":null,"abstract":"Objective To explore the scope of building emergency medical security mechanism in urban paved road environment, and to provide reference, sample data and improvement suggestions for building emergency medical security mechanism in such specific environment. Methods The data of rescue personnel deployment, rescue materials allocation, rescue force monitoring, actual rescue situation, emergency plan and relevant regulations setting, training and other aspects of the emergency medical security mechanism in March and April 2023 were collected, and the data were analyzed. Results (1) The hiking distance was 40km and the road conditions were urban paved roads. There were 1150 official trekkers and 65 people were treated medically. (2) The most common symptoms of outdoor hiking included skeletal muscle injury (19.48%), foot skin and soft tissue injury (18.17%), fever (2.61%) and diarrhea (0.61%). (3) In March, 18.36% of the core medical team members and 20.41% of the first aid volunteers who underwent systematic training took up the task of supporting hiking activities. In April, the core medical team personnel who undertook the task of supporting hiking activities accounted for 1.23% of the total number of the security team, and the first aid volunteers who underwent systematic training accounted for 37.04%. (4) According to local conditions, the multi-vehicle rescue and transport mode was adopted, which was combined with the modified commercial rescue vehicle (42.86%) with the on-board emergency medical unit (EMU) and the ordinary ambulance (28.57%). (5) More than 700 pieces of 34 kinds of medical materials and 40 sets of mobile communication equipment, which were put into use after the feasibility study of the expert group and the technical group, guaranteed the competition from the hardware level. Conclusion The construction of emergency medical support mechanism in outdoor walking sports needs to pay attention to environmental characteristics, operation mode of support team, personnel and adaptability training, equipment and deployment of medical support materials, deployment and cooperation of communication and transport capacity, reasonable support plan and other factors. Medical volunteers who have been systematically trained can undertake part of outdoor medical rescue work. Pre-activity training and regular re-training of medical volunteers can ensure the safety of outdoor activities.","PeriodicalId":502774,"journal":{"name":"INTERNATIONAL JOURNAL OF MEDICAL SCIENCE AND CLINICAL RESEARCH STUDIES","volume":"35 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140236117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Monocytes and Fibrinogen as Biomarkers in Type 2 Diabetes Mellitus 作为 2 型糖尿病生物标志物的单核细胞和纤维蛋白原
INTERNATIONAL JOURNAL OF MEDICAL SCIENCE AND CLINICAL RESEARCH STUDIES Pub Date : 2024-03-15 DOI: 10.47191/ijmscrs/v4-i03-17
M. Crisci, Fabiana Flagiello, Giovanni Lepore, Federica Feleppa, A. Crisci
{"title":"Monocytes and Fibrinogen as Biomarkers in Type 2 Diabetes Mellitus","authors":"M. Crisci, Fabiana Flagiello, Giovanni Lepore, Federica Feleppa, A. Crisci","doi":"10.47191/ijmscrs/v4-i03-17","DOIUrl":"https://doi.org/10.47191/ijmscrs/v4-i03-17","url":null,"abstract":"Background: In the diagnosis of diabetic foot, in addition to the inflammatory biomarkers that have been widely interested and used, for example procalcitonin, C-reactive protein (CRP), ESR, leukocyte count, neutrophil count, Fibrinogen and Monocytes are considered as biomarkers in this study. possible. Methods: A prospective study was designed to examine the utility of fibrinogen and monocytes in estimating disease severity in patients with DFU (Diabetic Foot Ulcer). The severity of DFU was assessed using the Wagner criteria distinguishing between patients with diabetic foot without ulcer (WDFU) and with non-infected diabetic foot ulcer (NIDFU) or with infected ulcer (IDFU). In this study the AA also wanted to correlate HbA1c to the concentration of Fibrinogen and the appearance of DFU, as well as the level of lymphocytes and monocyte precursors of macrophages in the evolution of ulcerated and non-ulcerated diabetic feet. Results: Mean blood fibrinogen values were significantly higher in patients with DFU grade ≧2 compared to those with DFU grade ≤1 (424.4±138.8 mg/dL versus 395.3±130.0 mg/dL; p=0.091). Fibrinogen values were correlated with CRP levels, neutrophils, ESR and leukocyte count. Monocytes presented a significant difference between non-diabetic patients with ulcer and without ulcer (0.41 vs 0.29 k/L; p=0.000) and between the diabetic without ulcer (WDFU) and non-diabetic without ulcer (NDWU) groups (0.39 vs 0.29 k/L; p=0.000). The Procalcitonin (PCT) value was <0.5 ng/dl, therefore it had no diagnostic significance. Only 1% of the values found were higher than 0.5 with an average of 1.04 ng/dl (range: 0.52-2.5). Conclusions: Neither monocytes nor HbA1c can be considered biomarkers for the risk of ulcer formation in the diabetic foot, but only as biomarkers of type 2 Diabetes Mellitus. Differently, fibrinogenemia, its pre/post intervention ratio, the  angle and the k value of thromboelastography (TEG), have a clinical significance on the risk of onset and development of ulcerated diabetic foot. The cut-off for ulcer formation for both the pre/post intervention ratio of fibrinogenemia and monocythemia is 1.10, with a sensitivity of 84.1% and a specificity of 24.5% for fibrinogen and 93.8% and 14.8% for monocytes.","PeriodicalId":502774,"journal":{"name":"INTERNATIONAL JOURNAL OF MEDICAL SCIENCE AND CLINICAL RESEARCH STUDIES","volume":"60 S1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140238235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Use of Botulinum Toxin and Pneumoperitoneum for Hernias with Loss of Dominance 使用肉毒杆菌毒素和气腹术治疗伴有支配功能丧失的疝气
INTERNATIONAL JOURNAL OF MEDICAL SCIENCE AND CLINICAL RESEARCH STUDIES Pub Date : 2024-03-15 DOI: 10.47191/ijmscrs/v4-i03-16
Daniela Medina Correa, Oscar Gregorio Gonzalez Cambero, Raúl Manuel Cota García, Alhan Fernando Castillo Valencia, María Fernanda Lara Solórzano, Sonia Elena Azucar Organista, José Fernando Montiel Castañeda, Brayant López García Montero, Maria del Rocio Barrera Figueroa
{"title":"Use of Botulinum Toxin and Pneumoperitoneum for Hernias with Loss of Dominance","authors":"Daniela Medina Correa, Oscar Gregorio Gonzalez Cambero, Raúl Manuel Cota García, Alhan Fernando Castillo Valencia, María Fernanda Lara Solórzano, Sonia Elena Azucar Organista, José Fernando Montiel Castañeda, Brayant López García Montero, Maria del Rocio Barrera Figueroa","doi":"10.47191/ijmscrs/v4-i03-16","DOIUrl":"https://doi.org/10.47191/ijmscrs/v4-i03-16","url":null,"abstract":"When the abdominal cavity's material migrates to the hernial sac (HSV) and the HSV/abdominal cavity volume ratio exceeds 25%, systemic alterations known as \"loss of domain\" occur, resulting in an estimated 5–30% of cases of post-incisional ventral hernia. Usage of botulinum toxin appears to be a secure way to do a tension-free repair on treatment for hernias with loss of dominance.","PeriodicalId":502774,"journal":{"name":"INTERNATIONAL JOURNAL OF MEDICAL SCIENCE AND CLINICAL RESEARCH STUDIES","volume":"38 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140238611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Long QT Syndrome and the Risk of Sudden Death in Adult Patients: An In-depth Analysis of Clinical Correlates and Prognostic Factors 长 QT 综合征与成年患者的猝死风险:深入分析临床相关因素和预后因素
INTERNATIONAL JOURNAL OF MEDICAL SCIENCE AND CLINICAL RESEARCH STUDIES Pub Date : 2024-03-14 DOI: 10.47191/ijmscrs/v4-i03-15
Donaldo Emiliano Silva López, Pedro Luis Matus Rojo, Veronica Duran Jimenez, Sussan Irlanda Méndez Ynostroza, Alma Alejandra Solano Mendoza, Claudia Paola Contreras Sáenz
{"title":"Long QT Syndrome and the Risk of Sudden Death in Adult Patients: An In-depth Analysis of Clinical Correlates and Prognostic Factors","authors":"Donaldo Emiliano Silva López, Pedro Luis Matus Rojo, Veronica Duran Jimenez, Sussan Irlanda Méndez Ynostroza, Alma Alejandra Solano Mendoza, Claudia Paola Contreras Sáenz","doi":"10.47191/ijmscrs/v4-i03-15","DOIUrl":"https://doi.org/10.47191/ijmscrs/v4-i03-15","url":null,"abstract":"Long QT Syndrome (LQTS) is a hereditary or acquired cardiac disorder characterized by delayed ventricular repolarization, predisposing affected individuals to life-threatening arrhythmias. While extensively studied in the pediatric population, there is a paucity of comprehensive research focusing on the clinical implications and prognostic markers of LQTS in adults. This article aims to elucidate the association between Long QT Syndrome and the heightened risk of sudden death in adult patients, exploring pertinent clinical correlates and potential prognostic factors. A systematic literature review was conducted to identify relevant studies published between 2000 and 2024, utilizing databases such as PubMed, MEDLINE, and Cochrane Library. Eligible articles were critically appraised for methodological quality and relevance to adult populations with Long QT Syndrome. Data extraction encompassed demographics, genetic predispositions, clinical presentations, electrocardiographic findings, and outcomes, focusing on the incidence of sudden death. Preliminary findings underscore the significance of a prolonged QT interval as a critical marker for adverse cardiovascular events in adults with Long QT Syndrome. Additionally, the study examines the impact of genotype-phenotype correlations, gender-related differences, and the influence of comorbidities on the risk of sudden death. Furthermore, potential therapeutic interventions and risk stratification strategies will be discussed in light of recent advancements in the field. This review aims to bridge the existing knowledge gap regarding Long QT Syndrome in the adult population, emphasizing the need for heightened clinical awareness, risk stratification, and targeted interventions to mitigate the risk of sudden death in affected individuals. The synthesis of current evidence will contribute to a more nuanced understanding of the complex interplay between Long QT Syndrome and adverse outcomes in adults, facilitating the development of tailored therapeutic approaches and improved patient outcomes","PeriodicalId":502774,"journal":{"name":"INTERNATIONAL JOURNAL OF MEDICAL SCIENCE AND CLINICAL RESEARCH STUDIES","volume":"19 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140242855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fingertip Reconstruction Techniques: An Update 指尖重建技术:最新进展
INTERNATIONAL JOURNAL OF MEDICAL SCIENCE AND CLINICAL RESEARCH STUDIES Pub Date : 2024-03-14 DOI: 10.47191/ijmscrs/v4-i03-14
Sarahi Hazour i Venegas, Mariana Gutiérrez Neri Pérez, Lizbeth Paloma Herrera Alarcón, Julio César González González, Jose Roberto Gonzalez Soto, Jairo Isaih Mendoza Argáez, Christopher Junnoel Dominguez Gutierrez, Carlos Mario González Garcia, Adair Axe l Cruz Cruz
{"title":"Fingertip Reconstruction Techniques: An Update","authors":"Sarahi Hazour i Venegas, Mariana Gutiérrez Neri Pérez, Lizbeth Paloma Herrera Alarcón, Julio César González González, Jose Roberto Gonzalez Soto, Jairo Isaih Mendoza Argáez, Christopher Junnoel Dominguez Gutierrez, Carlos Mario González Garcia, Adair Axe l Cruz Cruz","doi":"10.47191/ijmscrs/v4-i03-14","DOIUrl":"https://doi.org/10.47191/ijmscrs/v4-i03-14","url":null,"abstract":"The hand portion that sustains injuries most frequently is the fingertip. For a practical and aesthetically acceptable result, flap repair can be required if replantation of a fingertip amputation is not feasible. This work examines frequently used reconstruction methods, emphasizing technical nuances and potential issues and how to prevent them.","PeriodicalId":502774,"journal":{"name":"INTERNATIONAL JOURNAL OF MEDICAL SCIENCE AND CLINICAL RESEARCH STUDIES","volume":"15 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140244027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diagnosis of Pulmonary Candida Non-albican in Immunocompetent Patient 免疫功能正常患者肺部非阿耳毕卡念珠菌的诊断
INTERNATIONAL JOURNAL OF MEDICAL SCIENCE AND CLINICAL RESEARCH STUDIES Pub Date : 2024-03-13 DOI: 10.47191/ijmscrs/v4-i03-12
Yoki Citra Perwira, Resyana Santoso, Stevia Ariella Pasande
{"title":"Diagnosis of Pulmonary Candida Non-albican in Immunocompetent Patient","authors":"Yoki Citra Perwira, Resyana Santoso, Stevia Ariella Pasande","doi":"10.47191/ijmscrs/v4-i03-12","DOIUrl":"https://doi.org/10.47191/ijmscrs/v4-i03-12","url":null,"abstract":"Back ground: Pulmonary candidiasis is a fungal airway infection caused by the genus candida species, often in immunocompromised patients, and it spreads through hematogenous or other diseases. This case report aims to inform that the disease is rare in immunocompetent patients and difficult to diagnose. Methods: Through a medical record search, a 40-year-old Indo-Chinese man complained of chest pain, cough, shortness of breath, and a lump in the neck. A history of pulmonary tuberculosis was completed after six months of treatment with no diabetes mellitus. Then, wheezing and rhonchi were heard during the physical examination of the lungs. When a contrast HRCT (high resolution computed tomography) examination was performed, fibrocalcification with a tree in a bud was found in the bilateral superior lobes of the lung, solid mass in the distal bronchus with atelectasis and enlarged paratracheal nodules. Then, a fungal culture of the right BAL (bronchoalveolar lavage) sample was found candida-non albican. Conclusion: Pulmonary candidiasis is not only common in immunocompromised patients but also in immunocompetent conditions; diagnosis using HRCT with contrast and fungal culture from BAL.","PeriodicalId":502774,"journal":{"name":"INTERNATIONAL JOURNAL OF MEDICAL SCIENCE AND CLINICAL RESEARCH STUDIES","volume":"2007 23","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140246403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dupuytren's Disease: A Review with a Surgical Approach 杜普伊特伦氏病:手术方法综述
INTERNATIONAL JOURNAL OF MEDICAL SCIENCE AND CLINICAL RESEARCH STUDIES Pub Date : 2024-03-13 DOI: 10.47191/ijmscrs/v4-i03-13
Héctor Manuel Suárez Ortega, Angélica Bacilio Pomposo, Alejandro Morales Rubio, Daniela Fernanda Carpio Escobar, Francisco Alberto Montaño Vasquez del Mercado, Ariadna Martinez Becerril, Marisela Estefhanía Trejo Rubio, Álvaro Sebastián Gutiérrez Macklis, Sergio Domínguez Mercado
{"title":"Dupuytren's Disease: A Review with a Surgical Approach","authors":"Héctor Manuel Suárez Ortega, Angélica Bacilio Pomposo, Alejandro Morales Rubio, Daniela Fernanda Carpio Escobar, Francisco Alberto Montaño Vasquez del Mercado, Ariadna Martinez Becerril, Marisela Estefhanía Trejo Rubio, Álvaro Sebastián Gutiérrez Macklis, Sergio Domínguez Mercado","doi":"10.47191/ijmscrs/v4-i03-13","DOIUrl":"https://doi.org/10.47191/ijmscrs/v4-i03-13","url":null,"abstract":"One prevalent fibroproliferative hand disorder is Dupuytren's disease (DD). Observation, non-operative management, and operative management are the three types of DD management. Percutaneous needle fasciotomy (PNF), open fasciotomy (OF), injections of Clostridium collagenase histolyticum (CCH), limited fasciectomy (LF), and dermofasciectomy are examples of operative therapies (DF). A overview is given of the many approaches to treating DD. This page outlines the many DD treatment methods, their advantages and disadvantages, and procedural guidelines.","PeriodicalId":502774,"journal":{"name":"INTERNATIONAL JOURNAL OF MEDICAL SCIENCE AND CLINICAL RESEARCH STUDIES","volume":"57 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140247671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical Profile and Outcome of Covid-19 Intensive Care Patients with Nosocomial Infections: A Single-Centred Experience from India Covid-19重症监护患者的临床概况和非社会性感染结果:印度单中心经验
INTERNATIONAL JOURNAL OF MEDICAL SCIENCE AND CLINICAL RESEARCH STUDIES Pub Date : 2024-03-11 DOI: 10.47191/ijmscrs/v4-i03-10
Dr. Mehul Shah, Dr. Ketan Kargiwar, Dr. Charmaine Almeida, Dr. Harshal Shah, Ms. Kavita Shalia, Mr. Shreyans Rai, Dr. Nirankar Bhutaka, Dr. Mayur Patel, Dr. Ayesha Tahsin Shaikh, Ms. Chandan i Parsani
{"title":"Clinical Profile and Outcome of Covid-19 Intensive Care Patients with Nosocomial Infections: A Single-Centred Experience from India","authors":"Dr. Mehul Shah, Dr. Ketan Kargiwar, Dr. Charmaine Almeida, Dr. Harshal Shah, Ms. Kavita Shalia, Mr. Shreyans Rai, Dr. Nirankar Bhutaka, Dr. Mayur Patel, Dr. Ayesha Tahsin Shaikh, Ms. Chandan i Parsani","doi":"10.47191/ijmscrs/v4-i03-10","DOIUrl":"https://doi.org/10.47191/ijmscrs/v4-i03-10","url":null,"abstract":"Background: Incidences of nosocomial infections in COVID-19 patients admitted to the intensive care unit (ICU) have become a common occurrence. Hospital-acquired infections (HAI) present increased mortality, cost-of-care, especially relevant in multidrug resistant (MDR) infections. Our study aimed to assess the clinical implications associated with HAI-infected COVID-19 patients. Patients and Methods: We conducted retrospective single-centred study on ICU-admitted adult COVID-19 patients for a year i.e., 2021-22 at a tertiary Indian institute and collated data of HAI epidemiological, clinical and microbiological reports. Results: Rate of HIA at our centre was estimated to be 10.29% and the mortality rate was 40.4%. 10 different organisms(Bacteria: 8, Fungi: 2) were detected in HAI, of which the incidence of Gram-negative infections (GNI) was highest i.e., 60% and that of Gram-positive infections (GPI)/Fungi (Fungi infected) were 20% each. Mortality was highest among GPI (36.67%), FI (13.46%), followed by and GPI (7.69%). Tocilizumab treatment decreased the risk of survivability with no significant difference in the treatment outcomes. Conclusion: This study provides a comprehensive picture of nosocomial infections characteristics among COVID-19patients and provides insights regarding the impact of treatment on the outcome of these patients with suggestions for strategies. We found that critically ill patients with COVID- 19 are at a high risk of developing HAI, especially MDR mediated CLABSI and CAUTI. Clinicians must therefore be cautious and mindful during implementing protocols for management of infectious complications with COVID-19 patients.","PeriodicalId":502774,"journal":{"name":"INTERNATIONAL JOURNAL OF MEDICAL SCIENCE AND CLINICAL RESEARCH STUDIES","volume":"19 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140254435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Liver Abscess Secondary to Acute Perforated Cholecystitis: Case Report and Literature Review 急性穿孔性胆囊炎继发肝脓肿:病例报告和文献综述
INTERNATIONAL JOURNAL OF MEDICAL SCIENCE AND CLINICAL RESEARCH STUDIES Pub Date : 2024-03-11 DOI: 10.47191/ijmscrs/v4-i03-11
Guerrero Barrera Octavio, Viurcos Sanabria Victoria Scarlett, Meza Sánchez Julio César
{"title":"Liver Abscess Secondary to Acute Perforated Cholecystitis: Case Report and Literature Review","authors":"Guerrero Barrera Octavio, Viurcos Sanabria Victoria Scarlett, Meza Sánchez Julio César","doi":"10.47191/ijmscrs/v4-i03-11","DOIUrl":"https://doi.org/10.47191/ijmscrs/v4-i03-11","url":null,"abstract":"Pyogenic liver abscess is a rare clinical entity, having a reported incidence of 1.1/100,000 to 3.6/100,000 people in western countries, and with a reported mortality between 5.6-10%, however, this mortality can increase up to 22% if there are multiple abscesses. The prevalence of acute cholecystitis is reported at 0.8-3.8%; Only 2% of all patients with cholelithiasis will present a gallbladder perforation, and the reported mortality in these cases has been reported between 12 to 16%. The most common site of perforation is the gallbladder fundus because it is the most distal portion, which leads to having less blood flow. Its clinical presentation is not specific, and the ultrasound is usually the first imaging tool for diagnosis. Treatment will depend on the clinical condition of each patient. Here we present an 88-year-old female case successfully treated with laparoscopic cholecystectomy and liver abscess drainage despite hemodynamic instabilityPyogenic liver abscess is a rare clinical entity, having a reported incidence of 1.1/100,000 to 3.6/100,000 people in western countries, and with a reported mortality between 5.6-10%, however, this mortality can increase up to 22% if there are multiple abscesses. The prevalence of acute cholecystitis is reported at 0.8-3.8%; Only 2% of all patients with cholelithiasis will present a gallbladder perforation, and the reported mortality in these cases has been reported between 12 to 16%. The most common site of perforation is the gallbladder fundus because it is the most distal portion, which leads to having less blood flow. Its clinical presentation is not specific, and the ultrasound is usually the first imaging tool for diagnosis. Treatment will depend on the clinical condition of each patient. Here we present an 88-year-old female case successfully treated with laparoscopic cholecystectomy and liver abscess drainage despite hemodynamic instability.","PeriodicalId":502774,"journal":{"name":"INTERNATIONAL JOURNAL OF MEDICAL SCIENCE AND CLINICAL RESEARCH STUDIES","volume":"57 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140253171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Beyond Traditional Boundaries: A Review on Calotropis gigantea’s Efficacy in Wound Healing 超越传统界限:石菖蒲在伤口愈合方面的功效综述
INTERNATIONAL JOURNAL OF MEDICAL SCIENCE AND CLINICAL RESEARCH STUDIES Pub Date : 2024-03-09 DOI: 10.47191/ijmscrs/v4-i03-08
Dea Permata, Daniel Adhie Saputra, Z. Meilawaty
{"title":"Beyond Traditional Boundaries: A Review on Calotropis gigantea’s Efficacy in Wound Healing","authors":"Dea Permata, Daniel Adhie Saputra, Z. Meilawaty","doi":"10.47191/ijmscrs/v4-i03-08","DOIUrl":"https://doi.org/10.47191/ijmscrs/v4-i03-08","url":null,"abstract":"Introduction: Wounds result from the disruption of cellular and anatomical continuity in living tissues due to external factors. Calotropis gigantea, also known as crown flower or giant milkweed (or \"biduri\" in Indonesia), is a small tree or shrub with white or purple flowers, widely used in traditional remedies. Its properties, including antimicrobial, cytotoxic, and wound-healing activities, have prompted this literature review to assess its efficacy in wound healing. Method: A thorough analysis of scientific findings and research conducted in the last 10 years, specifically after January 1, 2014, was undertaken. Data were collected from reputable databases, such as PubMed, Web of Science, and ScienceDirect. After applying publication limitations, three manuscripts were selected as the final outcomes of the review process. Result: The analysis of multiple studies reveals that C. gigantea possesses wound healing properties attributed to phytochemical constituents like flavonoids, tannins, alkaloids, and saponin. These constituents play vital roles in each stage of wound healing, including the inflammatory reaction, proliferation, and remodeling stages. Additionally, C. gigantea promotes wound healing, leaving minimal scar residues. Conclusion: Calotropis gigantea has demonstrated its ability to enhance wound healing through various mechanisms, including astringency, antibacterial activity, promotion of homeostasis, facilitation of collagen synthesis, enhancement of re-epithelialization, and stimulation of cell proliferation via its phytochemical constituents. However, due to the scarcity of recent studies, the plant's true efficacy in wound healing remains unclear.","PeriodicalId":502774,"journal":{"name":"INTERNATIONAL JOURNAL OF MEDICAL SCIENCE AND CLINICAL RESEARCH STUDIES","volume":"152 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140256685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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