免疫功能正常患者肺部非阿耳毕卡念珠菌的诊断

Yoki Citra Perwira, Resyana Santoso, Stevia Ariella Pasande
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摘要

背景知识:肺念珠菌病是由念珠菌属引起的真菌性气道感染,常发生于免疫力低下的患者,通过血源性或其他疾病传播。本病例报告旨在说明该病在免疫功能正常的患者中较为罕见,且难以诊断。研究方法通过病历检索,一名 40 岁的印度华裔男子主诉胸痛、咳嗽、气短和颈部肿块。治疗 6 个月后,填写了肺结核病史,无糖尿病。随后,在对肺部进行体检时听到了喘息和啰音。在进行造影剂 HRCT(高分辨率计算机断层扫描)检查时,发现双侧肺上叶纤维钙化,呈树枝状,远端支气管内有实性肿块,伴有肺不张和气管旁结节增大。随后,对右侧 BAL(支气管肺泡灌洗液)样本进行真菌培养,发现了念珠菌-非白念珠菌。结论是肺念珠菌病不仅常见于免疫力低下的患者,在免疫力正常的情况下也很常见;诊断时应使用带对比剂的 HRCT 和 BAL 真菌培养。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Diagnosis of Pulmonary Candida Non-albican in Immunocompetent Patient
Back ground: Pulmonary candidiasis is a fungal airway infection caused by the genus candida species, often in immunocompromised patients, and it spreads through hematogenous or other diseases. This case report aims to inform that the disease is rare in immunocompetent patients and difficult to diagnose. Methods: Through a medical record search, a 40-year-old Indo-Chinese man complained of chest pain, cough, shortness of breath, and a lump in the neck. A history of pulmonary tuberculosis was completed after six months of treatment with no diabetes mellitus. Then, wheezing and rhonchi were heard during the physical examination of the lungs. When a contrast HRCT (high resolution computed tomography) examination was performed, fibrocalcification with a tree in a bud was found in the bilateral superior lobes of the lung, solid mass in the distal bronchus with atelectasis and enlarged paratracheal nodules. Then, a fungal culture of the right BAL (bronchoalveolar lavage) sample was found candida-non albican. Conclusion: Pulmonary candidiasis is not only common in immunocompromised patients but also in immunocompetent conditions; diagnosis using HRCT with contrast and fungal culture from BAL.
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