{"title":"Analysis of Changes in Bone Mineral Density by Disability Level in Patients with Myotonic Dystrophy Myopathy","authors":"Askeri Türken , Haşim Çapar","doi":"10.1016/j.jocd.2025.101584","DOIUrl":"10.1016/j.jocd.2025.101584","url":null,"abstract":"<div><div><em>Purpose/introduction:</em> The aim of this study was to determine which method can determine bone mineral changes in patients with Myotonic Dystrophy at an early age by applying age classification and Modified Rankin Scale for Neurological Disability (MRSND).</div><div><em>Methods:</em> This descriptive, cross-sectional and retrospective study was conducted in 52 myopathy patients diagnosed with myotonic dystrophy. Analyses were performed using SPSS 25 and STATA 14. Frequency and percentage, mean and standard deviation values were reported and Pearson correlation, t-test, ANOVA and multiple linear regression analyses were performed. Confidence levels of 0.10, 0.05 and 0.01. The study complies with the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement guidelines for reporting cross-sectional studies (STROBE CHECKLIST).</div><div><em>Results:</em> According to the regression analysis results, body mass index had a positive effect on Femoral Z Score (<em>p</em> < 0.01). In addition, vitamin D had a positive effect on Femoral Z Score (<em>p</em> < 0.05). On the other hand, MRSND had a negative effect on Femoral Z Score (<em>p</em> < 0.01).</div><div><em>Conclusion:</em> Myotonic dystrophic myopathy has been shown to impair the mineral structure of bone. Patients with this condition have been shown to recognize possible changes in their bones earlier in using the MRSND scale.</div></div>","PeriodicalId":50240,"journal":{"name":"Journal of Clinical Densitometry","volume":"28 2","pages":"Article 101584"},"PeriodicalIF":1.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143761152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hoc Nguyen Van , Khanh Nguyen Manh , Hoang Le Xuan
{"title":"Periprosthetic Bone Mineral Density Change after Total Knee Arthroplasty in Vietnamese Population","authors":"Hoc Nguyen Van , Khanh Nguyen Manh , Hoang Le Xuan","doi":"10.1016/j.jocd.2025.101583","DOIUrl":"10.1016/j.jocd.2025.101583","url":null,"abstract":"<div><div><em>Objectives:</em> After total knee arthroplasty (TKA), bone structure changes around prosthetics gradually appear. Adverse changes, such as decreased bone mineral density (BMD) and bone remodeling, can lead to joint loosening, affecting surgical outcomes. The study aims to detect BMD changes in the bone around the artificial knee early after TKA.</div><div><em>Methods:</em> We performed a prospectively descriptive study on 54 patients who were operated at Viet Duc University Hospital from 4/2017 to 4/2019. Bone density was measured using dual-energy X-ray absorptiometry (DEXA) at the seventh days, 3,6,12, and 24 months post-surgery.</div><div><em>Results:</em> The BMD in the medial metaphyseal region of interest decreased by 10.36 %, 11.5 %, 11.88 %, and 12.13 % at 3, 6, 12, and 24 months respectively, compared to 7 days post-surgery. The lateral metaphyseal region of interest decreased by 6.09 %, 6.47 %, 6.97 %, and 7.1 % and the tibial diaphyseal region of interest decreased by 3.75 %, 4.66 %, 5.91 %, and 5.8 % over the same follow-up periods. The BMD in the femoral condyle region of interest decreased by 8.15 %, 8.62 %, 9.24 %, and 10.65 % compared to the corresponding 7-day period at 3,6,12, and 24 months post-surgery.</div><div><em>Conclusion:</em> The periprosthetic BMD rapidly reduced in the first 3 months, then gradually decreased. After 24 months of follow-up, the BMD in the medial metaphyseal region of interest decreased the most.</div></div>","PeriodicalId":50240,"journal":{"name":"Journal of Clinical Densitometry","volume":"28 3","pages":"Article 101583"},"PeriodicalIF":1.7,"publicationDate":"2025-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143760527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Optimal kidney-tonifying traditional chinese medicines for postmenopausal osteoporosis: A network meta-analysis of randomized controlled trials","authors":"Xin'e Zhong , Liyun Li , Weiliang Wan","doi":"10.1016/j.jocd.2025.101581","DOIUrl":"10.1016/j.jocd.2025.101581","url":null,"abstract":"<div><div><em>Objective:</em> To evaluate the efficacy and safety of different kidney-tonifying Chinese medicines (KTCMs) combined with bisphosphonates (BPs) in postmenopausal osteoporosis (PMOP) patients.</div><div><em>Methods:</em> This study included 15 randomized controlled trials (RCTs) involving a total of 1,360 PMOP patients to compare the efficacy and safety of various KTCMs combined with BPs. A systematic search was conducted in eight medical databases (CNKI, PUBMED, Web of Science, Cochrane, EMBASE, Wanfang, VIP, and TCM Online). The inclusion criteria were as follows: (1) participants were postmenopausal women with PMOP; (2) the intervention involved different KTCMs combined with BPs; (3) outcome measures included pain Visual Analog Scale (VAS) scores, lumbar spine bone mineral density (BMD), femoral neck BMD, serum osteocalcin levels, and the incidence of adverse events. A network meta-analysis was performed to integrate data, calculating mean differences (MD) with 95 % confidence intervals (CIs). SUCRA values were used to rank treatment efficacy and assess the relative advantages of different regimens. League tables were used to visually present direct and indirect comparisons of treatments, while funnel plots were used to evaluate publication bias. The quality of the included studies was assessed using the Cochrane risk-of-bias tool.</div><div><em>Results:</em> GSK + BPs and JWEX + BPs were the most effective in pain relief, while GSK + BPs showed the best efficacy in improving lumbar spine and femoral neck BMD. LWDH + BPs demonstrated superior performance in promoting bone metabolism. Safety analysis indicated a low incidence of adverse events, with no statistically significant difference between the experimental and control groups (<em>p</em> > 0.05).</div><div><em>Conclusion:</em> This study suggests that GSK + BPs and JWEX + BPs are the most effective combinations for pain relief and BMD improvement, while LWDH + BPs and GSK + BPs have advantages in promoting bone metabolism. The combination of KTCMs with BPs can effectively improve PMOP with high safety, offering significant clinical value.</div></div>","PeriodicalId":50240,"journal":{"name":"Journal of Clinical Densitometry","volume":"28 2","pages":"Article 101581"},"PeriodicalIF":1.7,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143684681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mina Ebrahimiarjestan , Miriam O'sullivan , Attracta Brennan , Erjiang E , Bryan Whelan , Lan Yang , Tingyan Wang , Carmel Silke , Ming Yu , Mary Dempsey , John J. Carey
{"title":"DXA and cardiovascular disease in rheumatoid arthritis: A scoping review","authors":"Mina Ebrahimiarjestan , Miriam O'sullivan , Attracta Brennan , Erjiang E , Bryan Whelan , Lan Yang , Tingyan Wang , Carmel Silke , Ming Yu , Mary Dempsey , John J. Carey","doi":"10.1016/j.jocd.2025.101582","DOIUrl":"10.1016/j.jocd.2025.101582","url":null,"abstract":"<div><div>DXA technology is widely available today in many regions of the world. There is a growing realization of the value of DXA not only for osteoporosis management but also for sports medicine, sarcopenia, and the assessment of cardiovascular disease and mortality. Such features may be of particular interest for populations with a greater risk of these outcomes such as those with diabetes mellitus or rheumatoid arthritis. Recent systematic reviews and meta-analyses show DXA can robustly predict fractures, cardiovascular disease, dementia and mortality. Rheumatoid arthritis (RA) is a chronic inflammatory disease affecting multiple organs including synovial joints, bone and other tissues. People suffering from RA have a greater propensity to osteoporotic fracture, cardiovascular disease, infection and premature death, which is well recognised. RA is the only unique disease included in some fracture risk algorithms such as FRAX, and so RA patients are often referred for a DXA scan to evaluate their risk of osteoporosis. We have previously shown vertebral fractures, aortic calcification and cardiovascular disease are prevalent in our RA population, with strong association. In this paper we performed a scoping review of published literature in Medline and Embase to better understand the current status of DXA and cardiovascular disease in RA populations. 822 papers were identified in an initial search of which 7 papers reflecting 2,038 RA patients from 7 different countries were included. Study design included 4 cross-sectional, 2 longitudinal and 1 case-control. All included associations with various cardiovascular measures, while only 1 included clinical events as an outcome. Our results suggest this is an area which remains relatively unexplored but has substantial important clinical potential.</div></div>","PeriodicalId":50240,"journal":{"name":"Journal of Clinical Densitometry","volume":"28 2","pages":"Article 101582"},"PeriodicalIF":1.7,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143704219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marcus Vinícius de Oliveira Cattem, Josely Correa Koury
{"title":"Bioelectrical phase angle and impedance vectors are related to leg hip-femur density and bone geometry parameters in adolescent male soccer players","authors":"Marcus Vinícius de Oliveira Cattem, Josely Correa Koury","doi":"10.1016/j.jocd.2025.101579","DOIUrl":"10.1016/j.jocd.2025.101579","url":null,"abstract":"<div><div><em>Background:</em> Bone geometry parameters are essential for evaluating bone health and fracture risk in soccer players, whose physical demands affect their bone characteristics. However, studies on adolescent soccer players linking raw bioelectrical data to bone data are lacking, in addition to potential discrepancies in phase angle (PhA) values obtained using single-frequency (SF-BIA) and multifrequency (MF-BIA) bioelectrical impedance devices.</div><div><em>Aims:</em> In this cross-sectional study, we aimed to compare raw bioelectrical impedance data (resistance (R), reactance (Xc), and PhA values) obtained using SF-BIA and MF-BIA devices and test the relationships among PhA and bioelectrical impedance vector analysis (BIVA) with bone mineral density (BMD), and leg hip-femur geometry (HF-G) parameters in adolescent male soccer players.</div><div><em>Methods:</em> Raw bioelectrical impedance data were assessed using the SF-BIA and MF-BIA devices at a frequency of 50 kHz. The HF-G parameters were obtained by dual-energy X-ray absorptiometry. BIVA was used to compare bone data considering BMD and HF-G median values.</div><div><em>Results:</em> Overall, 59 adolescent male soccer players participated in this study. Raw SF-BIA data had lower R values (-19.3 %, <em>p</em> < 0.001), but higher Xc (+5.3 %, <em>p</em> < 0.001) and PhA values (+20.3 %, <em>p</em> < 0.001) than when using MF-BIA data. PhA values obtained using SF-BIA (<em>r</em> = 0.27, <em>p</em> = 0.04) or MF-BIA (<em>r</em> = 0.43, <em>p</em> < 0.001) were positively correlated with total hip-femur BMD. Considering BIVA, the ellipses differed for the total BMD (<em>p</em> = 0.0018), neck BMD (<em>p</em> = 0.026), and cross-sectional area (<em>p</em> = 0.024).</div><div><em>Conclusion:</em> The PhA and R values obtained using SF-BIA were higher than those obtained using MF-BIA, possibly because of the technological differences between the devices. However, the MF-BIA data suggests that PhA and BIVA can be used as tools for continuous use to warn of possible imbalances in bone tissue.</div></div>","PeriodicalId":50240,"journal":{"name":"Journal of Clinical Densitometry","volume":"28 2","pages":"Article 101579"},"PeriodicalIF":1.7,"publicationDate":"2025-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143725633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
John T. Schousboe , Neil Binkley , William D. Leslie
{"title":"The association of hip bone mineral density (BMD) with incident major osteoporotic and hip fractures varies by body mass index","authors":"John T. Schousboe , Neil Binkley , William D. Leslie","doi":"10.1016/j.jocd.2025.101577","DOIUrl":"10.1016/j.jocd.2025.101577","url":null,"abstract":"<div><div><em>Background:</em> Bone mineral density (BMD) measurement is less precise amongst those with body mass index (BMI) > 30 kg/m<sup>2</sup>. We hypothesized that the association of BMD with incident hip and major osteoporotic fractures (MOF; hip, clinical vertebral, forearm, or humerus) becomes weaker with increasing BMI.</div><div><em>Methodology:</em> Our study population was 75,391 individuals age ≥ 50 years who had a bone density test in the province of Manitoba 1998 to 2018. BMD of the total hip was assessed on GE Lunar densitometers. Incident MOF and hip fractures were ascertained using linked health claims data over a mean (SD) follow-up of 8.6 (5.3) years. The associations of total hip BMD with incident major osteoporotic and hip fractures were estimated with Cox proportional hazards models including an interaction term between BMI category and BMD to test if the association of BMD with incident fractures varies by BMI.</div><div><em>Result:</em> The multivariable adjusted associations of total hip BMD with incident MOF did not vary by BMI (hazard ratio [HR] 1.56, 95 % C.I. 1.30, 1.85 for BMI ≥ 40 kg/m<sup>2</sup>; HR 1.36, 95 % C.I. 1.17, 1.58 for BMI <18.5 kg/m<sup>2</sup>; p-value for interaction 0.14). However, the association of total hip BMD with incident hip fracture was stronger for those with BMI ≥ 35 kg/m<sup>2</sup> (HR 2.16, 95 % C.I. 1.71, 2.74) compared to those with BMI <18.5 kg/m<sup>2</sup> (HR 1.48, 95 % C.I. 1.19, 1.84, p-value 0.001 for interaction).</div><div><em>Conclusion:</em> The associations of total hip BMD with incident major osteoporotic and hip fracture are as strong for those with very high BMI as for those with normal BMI. However, total hip BMD may have a weaker association with incident hip fracture among underweight individuals. Further studies to confirm and explain this finding are warranted.</div></div>","PeriodicalId":50240,"journal":{"name":"Journal of Clinical Densitometry","volume":"28 2","pages":"Article 101577"},"PeriodicalIF":1.7,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143519721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Artificial intelligence for opportunistic osteoporosis screening with a Hounsfield Unit in chronic obstructive pulmonary disease patients","authors":"Yali Li, Yan Wu","doi":"10.1016/j.jocd.2025.101576","DOIUrl":"10.1016/j.jocd.2025.101576","url":null,"abstract":"<div><div><em>Introduction:</em> To investigate the accuracy of an artificial intelligence (AI) prototype in determining bone mineral density (BMD) in chronic obstructive pulmonary disease (COPD) patients using chest computed tomography (CT) scans.</div><div><em>Methodology:</em> This study involved 1276 health checkups and 1877 COPD patients who underwent chest CT scans from April 2020 to December 2021. Automated identification, segmentation, and Hounsfield Unit (HU) measurement of the thoracic vertebrae were performed using the musculoskeletal module of the AI-Rad Companion Chest CT (Siemens Healthineers, Er langen, Germany). Patients were divided into three groups: normal BMD, osteopenia, and osteoporosis, with quantitative CT (QCT) as the standard for analysis. The correlation between the HU and BMD values from T8 to T12 and T11-T12 vertebrae was analyzed using Linear regression analysis. The diagnostic performance of the HU values from T8 to T12 and T11-T12 vertebrae for osteoporosis was evaluated using the receiver operating characteristic curve.</div><div><em>Results:</em> The HU values strongly correlated with BMD values in health checkups and COPD patients (R<sup>2</sup>=0.881‒0.936 and 0.863‒0.927, <em>P</em> < 0.001). The Box-and-Whisker plot showed significant differences between HU and BMD values for T11-T12 vertebrae in normal BMD, osteopenia, and osteoporosis groups in two datasets (<em>P</em> < 0.001). The AUC was 0.970-0.982 and 0.944-0.961 in health checkups and COPD patients for detecting osteoporosis, with a sensitivity of 92.27 %‒97.42 % and 79.48 %‒90.24 % and a specificity of 86.35 %‒92.69 % and 82.81 %‒90.94 %. The optimal thresholds were 99.5‒120.5 HU and 104.5‒123.5 HU, respectively.</div><div><em>Conclusions:</em> The AI software achieved high accuracy for automatic opportunistic osteoporosis screening in COPD patients, which may be a complementary method for quickly screening the population at high risk of osteoporosis.</div></div>","PeriodicalId":50240,"journal":{"name":"Journal of Clinical Densitometry","volume":"28 2","pages":"Article 101576"},"PeriodicalIF":1.7,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143549597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ellen B. Fung , Iman Sarsour , Raquel Manzo , Ashutosh Lal
{"title":"Bone quality is associated with fragility fracture in patients with hemoglobinopathies","authors":"Ellen B. Fung , Iman Sarsour , Raquel Manzo , Ashutosh Lal","doi":"10.1016/j.jocd.2025.101565","DOIUrl":"10.1016/j.jocd.2025.101565","url":null,"abstract":"<div><div><em>Background:</em> Low bone mass, defined as a bone mineral density (BMD) Z-score ≤-2.0, is common in adults with thalassemia (Thal) and sickle cell disease (SCD), though disease-specific artifacts may contribute to inaccuracies in BMD assessment. Trabecular bone score (TBS), an indicator of bone quality, is not susceptible to these challenges and may improve fracture risk prediction.</div><div><em>Methods:</em> A retrospective chart review was conducted in patients with Thal or SCD who had at least one spine BMD scan by DXA in the past 10 years. The most recent scan was reanalyzed for bone quality with abnormal defined as TBS <1.2. Fracture prevalence was determined by patient report with medical record validation. Patients were compared to healthy controls who participated in previous research.</div><div><em>Results:</em> Data were abstracted from 126 patients with Thal (31.7 ± 11.9 yrs, 51 % Male), 170 with SCD (24.6 ± 13.5 yrs, 43 % Male), and 64 controls (25.9 ± 8.0 yrs, 17 % Male). Abnormal TBS was more common in Thal (26 %) or SCD (7 %) compared to controls (0 %, <em>p</em> < 0.001). Fracture prevalence was greater in Thal (36 %) compared to SCD (23 %) and controls (16 %, <em>p</em> = 0.005). Fragility fractures were not observed in controls but constituted 21 % of fractures in Thal and 15 % in SCD. After adjusting for age and hypogonadism, low bone mass was associated with an increased fracture prevalence (OR: 1.8, 95 % CI: 1.03, 3.23; <em>p</em> = 0.041), but not with fragility fracture. In contrast, abnormal TBS was strongly associated with fragility fracture after adjustment for age, sex, and BMI (OR: 11.4, 95 % CI: 2.2, 59.1, <em>p</em> = 0.004).</div><div><em>Conclusions:</em> Bone quality by TBS may be a valuable tool in predicting the risk of fragility fractures in young adults with hemoglobinopathies and should be considered when making decisions for anti-resorptive therapy in those with low BMD naive to fracture or where disease-specific artifacts complicate accurate spine assessment by BMD alone.</div></div>","PeriodicalId":50240,"journal":{"name":"Journal of Clinical Densitometry","volume":"28 2","pages":"Article 101565"},"PeriodicalIF":1.7,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143142900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tamara Hew-Butler , Edward Kerr III , Gloria Martinez Perez , Jordan Sabourin , Valerie Smith-Hale , Ruben Mendoza
{"title":"Evaluating lower limits of body fat percentage in athletes using DXA","authors":"Tamara Hew-Butler , Edward Kerr III , Gloria Martinez Perez , Jordan Sabourin , Valerie Smith-Hale , Ruben Mendoza","doi":"10.1016/j.jocd.2025.101564","DOIUrl":"10.1016/j.jocd.2025.101564","url":null,"abstract":"<div><div>Body fat percentage (BF%) is routinely measured in athletes to monitor training and dietary interventions. Dual energy x-ray absorptiometry (DXA) is widely considered the gold standard body composition measurement technique, but DXA BF% values measure consistently higher than other techniques. Therefore, the main purpose of this study is to determine the lowest DXA-estimated whole-body fat mass in free-living athletes with unrestricted access to food. In this cross-sectional analyses, 732 participants across 18 competitive sports (643 athletes; 88 %) plus two (male and female) “non-athlete” male and female cohorts (89 non-athletes; 12 %) underwent a whole-body DXA scan using a Horizon A Hologic™ device (software version 13.6.0.5; TBAR 1209), performed and analyzed by a single operator. The average BF % in 454 males (20.9 ± 3.8 years) was 18.2 ± 4.9 % (range 10.3 - 37.2 %), with basketball players having the lowest BF% (15.3 ± 2.6 %) and non-athletes having the highest BF% (21.6 ± 5.4 %) (1-way ANOVA between 10 teams: F = 12.3; p < 0.0001). The average BF% in 278 females (21.3 ± 5.5 years) was 27.1 ± 5.1 % (range 16.2 - 45.3 %), with runners having the lowest BF% (23.5 ± 3.5 %) and non-athletes having the highest BF% (31.7 ± 6.3 %) (1-way ANOVA between 10 teams F = 12.9; p < 0.0001). In absolute values (kg), the average body fat for males was 19.9 ± 8.0 kg (range 6.7 - 62.0 kg) and 18.9 ± 6.4 kg (range 9.2 - 49.7 kg) for females. These data suggest that the lower limits of whole-body fat mass in free-living competitive athletes is approximately 10 % for males and 16 % for females. Whether these DXA-derived fat thresholds represent “healthy” levels, or how much of these DXA-derived fat depots represent essential fat stores located within lean soft tissue mass, remains unclear.</div></div>","PeriodicalId":50240,"journal":{"name":"Journal of Clinical Densitometry","volume":"28 2","pages":"Article 101564"},"PeriodicalIF":1.7,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143054071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Amal Antoun , Eric Watelain , Antonio Pinti , Nour Khalil , Abdel-Jalil Berro , Elie Maliha , Youssef Bassim , Rawad El Hage
{"title":"Influence of two strength training modalities (hypertrophy vs. contrast training) on muscular strength, bone health parameters and quality of life in a group of older adults with low skeletal muscle mass index","authors":"Amal Antoun , Eric Watelain , Antonio Pinti , Nour Khalil , Abdel-Jalil Berro , Elie Maliha , Youssef Bassim , Rawad El Hage","doi":"10.1016/j.jocd.2025.101563","DOIUrl":"10.1016/j.jocd.2025.101563","url":null,"abstract":"<div><div>The main aim of the current study was to compare the effects of two strength training modalities (hypertrophy vs. contrast training) on bone health parameters, physical performance and quality of life in a group of subjects aged 60 and above with low skeletal muscle mass index (SMI). 45 older adults voluntarily participated in this study, but only 41 (22 women and 19 men) completed it. The participants were assigned to 3 different groups: control group (CG; <em>n</em> = 15), contrast training group (CTG; <em>n</em> = 13) and hypertrophy training group (HTG; <em>n</em> = 13). The duration of the training protocol was six months. The experimental groups performed two sessions of strength training per week; the duration of each session was forty-five minutes. Several measurements (which included anthropometrics, body composition, bone parameters, maximal strength parameters, physical performance parameters, fracture risk and quality of life) were performed in the three groups before and after the six-month training period. The different measurements of the protocol were carried out under the same conditions with identical materials and investigators for all the participants and for each approach. The current study has demonstrated that the two training modalities show common benefits such as improving maximal strength, physical performance and quality of life parameters but have no significant effects on bone mineral density (BMD) and bone mineral content (BMC). The influence of training was marked more for improving maximal strength and reducing fracture risk for the contrast training group (who performs movements at high speed) compared to the hypertrophy training group (who performs movements at spontaneous speed). In conclusion, this study shows that both resistance training programs are effective in improving maximal strength, physical performance and quality of life in older adults with low SMI. However, this 6-month intervention was not sufficient to significantly increase BMC nor BMD values in this population.</div></div>","PeriodicalId":50240,"journal":{"name":"Journal of Clinical Densitometry","volume":"28 2","pages":"Article 101563"},"PeriodicalIF":1.7,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143048455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}