Journal of Clinical Densitometry最新文献

{"title":"Evaluation of AI-based spine segmentation (SpS) for the analysis of lumbar spine dual energy X-ray absorptiometry scans","authors":"Guillaume Gatineau Doctorant (Primary Author) ,&nbsp;El Hassen Ahmed Lebrahim (Contributing Author Data Scientist) ,&nbsp;Karen Hind (Contributing Author) ,&nbsp;Lamy Olivier Prof., MD, PhD (Contributing Author) ,&nbsp;Elena Gonzalez Rodriguez MD, PhD (Contributing Author) ,&nbsp;Lionel Beaugé CTO (Contributing Author) ,&nbsp;Didier Hans Prof., MD, PhD Professor (Contributing Author)","doi":"10.1016/j.jocd.2023.101410","DOIUrl":"10.1016/j.jocd.2023.101410","url":null,"abstract":"<div><h3>Purpose/Aims</h3><p>The aim of this study was to evaluate a new deep-learning artificial intelligence (AI) -based model for automated SpS. First, we compared bone mineral density (BMD), trabecular bone<span> score (TBS) and bone surface area outcomes across three methods for SpS: 1) the manufacturer default, 2) the clinical DXA expert (criterion) and 3) the new AI-application. Second, we examined longitudinal reproducibility for the measurement of spine surface area.</span></p></div><div><h3>Rationale/Background</h3><p>The antero-posterior (AP) lumbar spine<span> dual energy X-ray absorptiometry (DXA) scan is an important diagnostic measure, used for the assessment of osteoporosis. The quality of the scan is dependent on the accuracy of the vertebral bone mask, derived from bone edge detection and spine segmentation (SpS).</span></p><p>Reducing technical error requires manual validation of the default bone mask for each scan. However, this can be time-consuming in practice.</p></div><div><h3>Methods</h3><p>A sub-sample of 130 women (mean age: 67.1; BMI: 25.2; with no vertebral anomalies) were selected from the OsteoLaus population cohort, having previously received two LS DXA scans (GE Lunar iDXA, encore v 18), 2.5 years apart. Scans were analyzed according to each of the three methods (default, clinical expert and AI), and the primary outcomes (BMD, TBS and surface area) were compared using Student's t-tests and one-way repeated measures-ANOVA. The coefficient of variation (CV%) for bone surface area was also computed.</p></div><div><h3>Results</h3><p>There were significant differences in mean BMD and TBS outcomes derived from the default bone mask method compared to the DXA clinical expert (p=0.01, Table 1). There were no differences in BMD and TBS derived using the AI SpS bone mask method compared to the DXA clinical expert (p=0.67, Table 1).</p><p>Reproducibility for bone surface area was superior for the clinical expert and the AI model compared to the default method (Table 2).</p></div><div><h3>Implications</h3><p>The AI based model demonstrated improved accuracy and reproducibility for lumbar spine bone segmentation compared to the default analysis method, and in close agreement with the clinical criterion. Overall, these results suggest that the new AI-based model for automated SpS may be a valuable tool for reducing time and improving accuracy for the analysis of lumbar spine DXA scans.</p></div>","PeriodicalId":50240,"journal":{"name":"Journal of Clinical Densitometry","volume":"26 3","pages":"Article 101410"},"PeriodicalIF":2.5,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44682423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Abaloparatide or Placebo on Bone Mineral Density in Acetabular Regions Corresponding to DeLee and Charnley Zones in Postmenopausal Women with Osteoporosis","authors":"Neil P. Sheth MD (Contributing Author) ,&nbsp;Mathias P. Bostrom MD (Contributing Author) ,&nbsp;Renaud Winzenrieth PhD (Contributing Author Speaker Biography) ,&nbsp;Ludovic Humbert PhD (Contributing Author) ,&nbsp;Leny Pearman PhD (Contributing Author) ,&nbsp;John Caminis MD (Contributing Author) ,&nbsp;Yamei Wang PhD (Contributing Author) ,&nbsp;John I. Boxberger PhD (Primary Author) ,&nbsp;Kelly Krohn MD (Contributing Author)","doi":"10.1016/j.jocd.2023.101396","DOIUrl":"https://doi.org/10.1016/j.jocd.2023.101396","url":null,"abstract":"<div><h3>Purpose/Aims</h3><p>To evaluate the effects of 6 and 18 mo of abaloparatide<span> (ABL) compared with placebo (PBO) on bone mineral density (BMD) in the acetabular<span> regions of postmenopausal women<span> with osteoporosis (OP).</span></span></span></p></div><div><h3>Rationale/Background</h3><p><span>Acetabular bone loss<span><span>, as may occur in OP, increases risk of acetabular fragility fractures and is associated with significant morbidity. In total </span>hip arthroplasty (THA), low acetabular BMD adversely affects primary stability, </span></span>osseointegration<span><span>, and migration of acetabular cups<span>. ABL is an osteoanabolic agent for the treatment of men and postmenopausal women with OP at high risk for fracture that increases BMD of the total hip, </span></span>femoral neck<span>, trochanter, and lumbar spine. Effects of ABL on acetabular BMD are unknown.</span></span></p></div><div><h3>Methods</h3><p>Hip DXA scans were obtained at baseline, 6, and 18 mo from a random subgroup of postmenopausal women (aged 49–86 y) from the phase 3 ACTIVE trial randomized to either ABL 80 µg/d or PBO (n=250/group).</p><p>Anatomical landmarks were identified in each DXA scan to virtually place a hemispherical shell model of an acetabular cup and define regions of interest corresponding to DeLee &amp; Charnley zones 1 (R1), 2 (R2), and 3 (R3). BMD changes compared to baseline were calculated for each zone. Statistical P values were based on a mixed-effect repeated measure model adjusted for BMI, age, and baseline BMD, with covariates including DXA scanner type, treatment group, visit, and treatment/visit interaction. DXA scans were aligned via intensity-based registration onto a reference scan to depict local mean changes in BMD.</p></div><div><h3>Results</h3><p>BMD in all zones were similar at baseline in the ABL and PBO groups. BMD significantly increased in the ABL group at 6 and 18 mo compared with PBO (all P&lt; 0.0001 vs PBO; Figure), with mean BMD increasing from baseline by 8.38% in R1, 7.25% in R2, and 9.73% in R3 at 18 months. BMD in the PBO group was relatively stable over time.</p></div><div><h3>Implications</h3><p>Treatment with ABL resulted in rapid and progressive increases in BMD of all 3 acetabular zones. Increasing acetabular BMD has the potential to improve acetabular strength, which may reduce risk of acetabular fragility fractures. With bone health optimization prior to THA, increased acetabular BMD via ABL may provide better primary stability and longevity of acetabular cups in postmenopausal women with OP.</p></div>","PeriodicalId":50240,"journal":{"name":"Journal of Clinical Densitometry","volume":"26 3","pages":"Article 101396"},"PeriodicalIF":2.5,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49734896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"DXA Assessment in Gender Diverse Youth","authors":"Sooji Kim BS (Primary Author Research Coordinator) ,&nbsp;H. Theodore Harcke MD (Contributing Author Pediatric Radiologist) ,&nbsp;Evan Graber DO (Contributing Author) ,&nbsp;Heidi H. Kecskemethy MS Ed, RDN, CBDT (Contributing Author)","doi":"10.1016/j.jocd.2023.101411","DOIUrl":"10.1016/j.jocd.2023.101411","url":null,"abstract":"&lt;div&gt;&lt;h3&gt;Purpose/Aims&lt;/h3&gt;&lt;p&gt;Evaluate DXA in gender diverse youth and examine interpretation of results using male and female reference values.&lt;/p&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Rationale/Background&lt;/h3&gt;&lt;p&gt;Gender affirming care in the US has increased over the past decade. Positions on DXA interpretation in gender diverse (GD) adults exist; guidelines for GD youth are being developed. Standard practice for prepubescent children seeking gender affirming medical care is to start pubertal suppression (PS). Bone mass accrual in the growing skeleton occurs during puberty and the impact of PS on bone mineral density (BMD) is unclear. We examine the practice of reporting results using both male and female norms.&lt;/p&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Methods&lt;/h3&gt;&lt;p&gt;Retrospective review of clinically obtained DXAs and clinical information regarding gender affirming medical care including PS, hormonal replacement therapy (HRT), Tanner score at DXA, fracture history, serum 25(OD)D level, and other bone or nutritional issues in children (&lt; 18 years) seen at our children's hospital prior to 1/11/2023. All had at least one DXA. BMD and z-score for total body less head (TBLH), lumbar spine (LS), and lateral distal femurs (LDF) regions 1 – 3 for both sexes were evaluated. Height-adjusted z-score (HAZ) was used for TBLH and LS. Serial DXA was assessed if available. We evaluated z-score patterns at all body sites comparing natal norms to opposite sex norms.&lt;/p&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Results&lt;/h3&gt;&lt;p&gt;Twenty-four GD children (12 natal female) with a mean age at first DXA of 13.1 years (9.9 to 17) were identified. Twenty-three received PS and 12 received HRT. Half had insufficient/deficient 25(OH)D status, and 33% had history of fracture, consistent with the general pediatric population. All had TBLH and LS; 23 had LDF scans. At first DXA, 13 of 24 (6 natal female) were on PS. Mean age of PS initiation differed by natal sex with girls starting at 12.4 years and boys starting at 14.7 years. Three patients received HRT; all had received PS. When comparing z-scores using both sex normative standards, only the LS showed consistent differences between the sexes: z-scores were lower in natal males using female norms and higher in natal females using male norms. Difference in z-scores varied at all other body sites between the sexes with no trend.&lt;/p&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Implications&lt;/h3&gt;&lt;p&gt;ISCD adult positions for transgender patients advises use of assigned gender reference values for calculation of z-scores. Utilizing this adult position creates problems for interpretation of DXA in children because z- scores are used in pediatrics and bone mass accrual and growth vary by sex and age. PS decreases growth trajectory and BMD further complicating interpretation of results and use of pediatric reference values.&lt;/p&gt;&lt;p&gt;Analyzing BMD results using both sex norms, using recommended size adjustments to BMD in pediatrics, and providing this information to the treating clinician for consideration of clinical context provides the ","PeriodicalId":50240,"journal":{"name":"Journal of Clinical Densitometry","volume":"26 3","pages":"Article 101411"},"PeriodicalIF":2.5,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47349992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bone Mineral Density and Dickkopf-1 in Adolescents with Non-Deletional Hemoglobin H Disease","authors":"Pattara Wiromrat ,&nbsp;Aree Rattanathongkom ,&nbsp;Napat Laoaroon ,&nbsp;Kunanya Suwannaying ,&nbsp;Patcharee Komwilaisak ,&nbsp;Ouyporn Panamonta ,&nbsp;Nantaporn Wongsurawat ,&nbsp;Nat Nasomyont","doi":"10.1016/j.jocd.2023.101379","DOIUrl":"10.1016/j.jocd.2023.101379","url":null,"abstract":"<div><p><em>Background:</em><span> Low bone mineral density (BMD) is prevalent in individuals with β-thalassemia and is associated with increased circulating dickkopf-1 concentration. These data are limited in α-thalassemia. Therefore, we aimed to determine the prevalence of low BMD and the association between BMD and serum dickkopf-1 in adolescents with non-deletional hemoglobin H disease, a form of α-thalassemia whose severity is comparable to β-thalassemia intermedia. </span><em>Methodology:</em><span><span> The lumbar spine and total body BMD were measured and converted into height-adjusted z-scores. Low BMD was defined as BMD z-score ≤ -2. Participant blood was drawn for measurement of dickkopf-1 and </span>bone turnover marker concentrations. </span><em>Results:</em><span><span><span> Thirty-seven participants with non-deletional hemoglobin H disease (59% female, mean age 14.6 ± 3.2 years, 86% Tanner stage ≥2, 95% regularly transfused, 16% taking prednisolone) were included. Over one year prior to the study, mean average pretransfusion hemoglobin, ferritin<span> and 25-hydroxyvitamin D concentrations were 8.8 ± 1.0 g/dL, and 958 ± 513 and 26 ± 6 ng/mL, respectively. When participants taking prednisolone were excluded, the prevalence of low BMD at the lumbar spine and total body was 42% and 17%, respectively. BMD at both sites was correlated positively with </span></span>body mass index z-score, and negatively with dickkopf-1 (all p-values &lt;0.05). There were no correlations among dickkopf-1, 25-hydroxyvitamin D, </span>osteocalcin<span><span> and C-telopeptide of type-I collagen. Multiple regression analysis showed dickkopf-1 inversely associated with total body BMD z-score adjusting for sex, bone age, body mass index, pre-transfusion hemoglobin, 25-hydroxyvitamin D, history of delayed puberty, type of </span>iron chelator and prednisolone use (p-value = 0.009). </span></span><em>Conclusions:</em> We demonstrated a high prevalence of low BMD in adolescents with non-deletional hemoglobin H disease. Moreover, dickkopf-1 inversely associated with total body BMD suggesting it may serve as a bone biomarker in this patient population.</p></div>","PeriodicalId":50240,"journal":{"name":"Journal of Clinical Densitometry","volume":"26 3","pages":"Article 101379"},"PeriodicalIF":2.5,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10287357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Associations of Lean Mass, Muscular Strength, and Physical Function with Trabecular Bone Score in Older Adults","authors":"Margaret P. Seaton ,&nbsp;Jeanne F. Nichols ,&nbsp;Mitchell J. Rauh ,&nbsp;Deborah M. Kado ,&nbsp;Julie Loebach Wetherell ,&nbsp;Eric J. Lenze ,&nbsp;David Wing","doi":"10.1016/j.jocd.2023.101370","DOIUrl":"10.1016/j.jocd.2023.101370","url":null,"abstract":"<div><p><em>Introduction/Background:</em><span><span> Trabecular bone score (TBS) is an indirect measurement of bone quality and microarchitecture determined from dual-energy X-ray absorptiometry (DXA) imaging of the </span>lumbar spine. TBS predicts fracture risk independent of bone mass/density, suggesting this assessment of bone quality adds value to the understanding of patients’ bone health. While lean mass and muscular strength have been associated with higher bone density and lower fracture risk among older adults, the literature is limited regarding the relationship of lean mass and strength with TBS. The purpose of this study was to determine associations of DXA-determined total body and trunk lean mass, maximal muscular strength, and gait speed as a measure of physical function, with TBS in 141 older adults (65-84 yr, 72.5 +/- 5.1 yr, 74% women). </span><em>Methodology:</em><span> Assessments included lumbar spine (L1-L4) bone density and total body and trunk lean mass by DXA, lower body (leg press) and upper body (seated row) strength by one repetition maximum tests, hand grip strength, and usual gait speed. TBS was derived from the lumbar spine DXA scan. Multivariable linear regression determined the contribution of proposed predictors to TBS. </span><em>Results:</em> After adjusting for age, sex, and lumbar spine bone density, upper body strength significantly predicted TBS (unadjusted/adjusted <em>R</em>²= 0.16/ 0.11, β coefficient =0.378, <em>p</em><span>=0.005), while total body lean mass index showed a trend in the expected direction (β coefficient =0.243, </span><em>p</em>=0.053). Gait speed and grip strength were not associated with TBS (<em>p</em>&gt;0.05). <em>Conclusion:</em> Maximum strength of primarily back muscles measured as the seated row appears important to bone quality as measured by TBS, independent of bone density. Additional research on exercise <em>training</em><span> targeting back strength is needed to determine its clinical utility in preventing vertebral fractures among older adults.</span></p></div>","PeriodicalId":50240,"journal":{"name":"Journal of Clinical Densitometry","volume":"26 3","pages":"Article 101370"},"PeriodicalIF":2.5,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9932647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Collaborative Approach to Bone Health","authors":"SHIBI A. Kunjumon (Primary Author)","doi":"10.1016/j.jocd.2023.101391","DOIUrl":"10.1016/j.jocd.2023.101391","url":null,"abstract":"&lt;div&gt;&lt;h3&gt;Purpose/Aims&lt;/h3&gt;&lt;p&gt;Background: Osteoporosis is a global problem; people living with osteoporosis have increased dramatically in the last few decades due to the aging population and changes in lifestyle. The project aims to improve post-fracture care and use a preventative service for compromised bone quality patients in the Emergency Room (ER). The QI project aims to increase ER providers' awareness about osteoporosis and to refer appropriately to Bone Health Clinic (BHC) to prevent future fractures.&lt;/p&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Rationale/Background&lt;/h3&gt;&lt;p&gt;&lt;span&gt;Methods: Most fractures are first treated in the ER, making ER the gateway for treating fractures. A fragility fracture (FF) &lt;/span&gt;care pathway&lt;span&gt; was developed to help providers to identify patients at risk for osteoporosis and guide the providers in placing appropriate referrals to BHC. Educational sessions for providers, FF care pathway posters, and modified EPIC discharge smart phrases for fracture patients that prompted the ER providers to add Bone Health recommendations while discharging the FF patients were developed as part of the framework. The number of new fragility fracture patients, including spine fractures, wrist, humerus, and ankle fractures seen in ER with appropriate BH recommendations, ultimately determined the project's success.&lt;/span&gt;&lt;/p&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Brief Description of the Undertaking/Best Practice&lt;/h3&gt;&lt;p&gt;The Plan-Do-Study-Act (PDSA) model created a process change and improved patient outcomes. The conceptual framework helped to implement the proposed change, ensured leadership and management support, and established the feedback process to sustain the implemented change. Post-fracture care process improvement enabled ER physicians to recommend patients to BHC to ensure appropriate osteoporosis management, resulting in improved care from 2% to 66% of patients with fragility fractures.&lt;/p&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Outcomes achieved/documented&lt;/h3&gt;&lt;p&gt;The outcome measure of the intervention is the percentage of bone health recommendations made by ER providers for fragility fracture patients. The ICD code with fragility fracture patients analyzed in ER data found that 0% to 25% percent of patients were recommended to the BHC through ER providers after the intervention. The process measures report the validity of the intervention and tracked 30% of ER providers who attended the educational session; 10% to 20% of ER providers adhered to the fragility fracture pathway recommendations. Ten percent of patients accepted the BHC referrals. In contrast, 10% of patients were admitted as in-patients after surgery, and 5% of patients were discharged to skilled nursing facilities or hospice for further care without accepting the bone health referrals. Balancing measures increase patient waiting time for BHC appointments to see the provider, estimated three to four weeks from discharge. The conceptual framework emphasizes sustaining improvements; thus, upon QI completion, weekly reports w","PeriodicalId":50240,"journal":{"name":"Journal of Clinical Densitometry","volume":"26 3","pages":"Article 101391"},"PeriodicalIF":2.5,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43490165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fragility Fracture Network Malaysia (FFNM) Fracture Liaison Service (FLS) Framework FFNM promotes multidisciplinary approach on fragility fracture care. It aims to create a national network of fragility fracture care. FLS is a relatively new approach fragility fracture care in Malaysia. The Framework functions as a systematic guide to achieve these goals. It provides a common platform for all FLS to work together for a successful outcome and sustainability. Minimum Common Dataset (MCD) has been incorporated into the Framework to have standardized data collection.","authors":"JOON KIONG LEE (Primary Author Speaker Biography) ,&nbsp;ELIZABETH GAR MIT CHONG (Contributing Author) ,&nbsp;JULIA PATRICK ENGKASAN (Contributing Author) ,&nbsp;SITI NURBAYA MOHD NAWI (Contributing Author Consultant Geriatrician) ,&nbsp;TERENCE ONG (Contributing Author Consultant Geriatrician) ,&nbsp;SANKARA KUMAR CHANDRASEKARAN (Contributing Author) ,&nbsp;PAUL JAMES MITCHELL (Contributing Author Consultant Orthopedic Surgeon)","doi":"10.1016/j.jocd.2023.101388","DOIUrl":"https://doi.org/10.1016/j.jocd.2023.101388","url":null,"abstract":"<div><h3>Purpose/Aims</h3><p>FFNM aims to create a national network of fragility fracture care, with the participation of various clinical specialists, allied health and primary care physician from different states throughout Malaysia. Fracture Liaison Service (FLS) is a relatively new approach and platform promoting fragility fracture care in Malaysia.</p></div><div><h3>Rationale/Background</h3><p>The Fragility Fracture Network of Malaysia (FFNM) which was formed in 2018, is a national organization aiming to promote multidisciplinary input on the three pillars of fragility fracture care which include post- fracture acute care, post-fracture rehabilitation and secondary fracture prevention.</p></div><div><h3>Brief Description of the Undertaking/Best Practice</h3><p>FFNM FLS Framework functions as a systematic guide to achieve these goals. It provides a common platform for all FLS to work together for a successful outcome and sustainability. It highlights the rationale and importance of an FLS to all who are interested in the initiation of FLS in their practice. The Framework provides a guide on how to initiate a new FLS or improve an existing FLS in their practice. It also illustrates the different models of care available and the success stories of some regional and global FLS models as a guide. A Minimum Common Dataset (MCD) has been designed and added into the Framework in order to assist all the FLS in Malaysia to have standardized data captured for comparison and assessment of Key Performance Indicators (KPI) that is crucial to improve services and optimize the benefit for patients.</p></div><div><h3>Outcomes achieved/documented</h3><p>In 2017, there was only one FLS service available (Beacon Hospital). In 2022, four years FFNM was formed, there are twenty FLS services available throughout the country, with eight being mapped on the International Osteoporosis Foundation (IOF) Capture the Fracture World Map. By establishing a framework, guidelines and standard of best practice in managing various fragility fractures, our patients presenting with fragility fractures will be allowed to return to their best functional status possible.</p></div><div><h3>Conclusions</h3><p>FFNM FLS Framework has been recognized and accepted as the guide for all existing FLS services to improve their outcome and also for all potential FLS services to initiate their FLS services in their hospitals.</p></div>","PeriodicalId":50240,"journal":{"name":"Journal of Clinical Densitometry","volume":"26 3","pages":"Article 101388"},"PeriodicalIF":2.5,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49737309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Medical imaging measurement of visceral adipose tissue thresholds associated with increased risk of cardiometabolic disease","authors":"J. Bennett, M. Wong, Carla Prado, S. Heymsfield, J. Shepherd","doi":"10.1016/j.jocd.2023.101387","DOIUrl":"https://doi.org/10.1016/j.jocd.2023.101387","url":null,"abstract":"","PeriodicalId":50240,"journal":{"name":"Journal of Clinical Densitometry","volume":"1 1","pages":""},"PeriodicalIF":2.5,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54678736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bibliometric Analysis of Geriatric Sarcopenia Therapies: Highlighting Publication Trends and Leading-Edge Research Directions","authors":"Kaixi Ding ,&nbsp;Wei Jiang ,&nbsp;Dingqi Li,&nbsp;Chaofang Lei,&nbsp;Chunping Xiong,&nbsp;Ming Lei","doi":"10.1016/j.jocd.2023.101381","DOIUrl":"10.1016/j.jocd.2023.101381","url":null,"abstract":"<div><p><span>The bibliometric analysis assesses the productivity of scholarship in a given field and provides information on the frontiers of relevant developments. However, no bibliometric analysis study has quantitatively analyzed publications in geriatric </span>sarcopenia<span><span> therapies. This study investigates the scholarly productivity and frontiers of publications in geriatric sarcopenia therapies. The bibliometric data came from English-language Web of Science Core Collection articles published between 1995 and October 19, 2022. Three software programs, R version 3.5.6, VOSviewer, and CiteSpace, were applied for this bibliometric analysis. In twenty-eight years, the annual publications in geriatric sarcopenia therapies have increased yearly, with an annual growth rate of 21.23 %. A total of 1379 publications have been published. The United States was the country with the highest number of publication signatures (n=1,537) (including joint publication releases), followed by Japan (n=1099). Journal of </span>Cachexia, Sarcopenia, and Muscle contributed the best journal publications (n=80). The newest hot subjects in the study about geriatric sarcopenia therapy include malnutrition, obesity, insulin resistance, and cancer. This bibliometric study presents a comprehensive overview of the current and future research directions in geriatric sarcopenia therapies over the past 28 years. Overall, this study has complemented the gaps in bibliometric analysis in geriatric sarcopenia therapies. This paper will provide a valuable reference for future research in geriatric sarcopenia therapies.</span></p></div>","PeriodicalId":50240,"journal":{"name":"Journal of Clinical Densitometry","volume":"26 3","pages":"Article 101381"},"PeriodicalIF":2.5,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9984583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effects of a 1-Year Recreational Kung Fu Protocol on Bone Health Parameters in a Group of Healthy Inactive Young Men","authors":"Nour Khalil ,&nbsp;Antonio Pinti ,&nbsp;Rawad El Hage","doi":"10.1016/j.jocd.2023.101418","DOIUrl":"10.1016/j.jocd.2023.101418","url":null,"abstract":"<div><p>The main aim of the current study was to explore the effects of a 1-year recreational Kung Fu protocol on bone health parameters (bone mineral content (BMC), bone mineral density (BMD), femoral neck geometry and composite indices of femoral neck strength) in a group of healthy inactive young men. 54 young inactive men voluntarily participated in this study, but only 51 of them completed it. The participants were assigned to 2 different groups: control group (n=31) and Kung Fu group (n=20). The Kung Fu group performed two sessions of recreational Kung Fu per week; the duration of each session was 45 minutes. The current study has demonstrated that whole body (WB) BMC, ultra-distal (UD) radius BMD, 1/3 radius BMD, total radius BMD, total forearm BMD, maximal strength, maximum oxygen consumption and jumping performance increased in the Kung Fu group but not in the control group. The percentages of variations in WB BMC, forearm BMD and physical performance parameters were significantly different between the two groups. In conclusion, this study suggests that recreational Kung Fu is an effective method to improve WB BMC, forearm BMD and physical performance parameters in young inactive men.</p></div>","PeriodicalId":50240,"journal":{"name":"Journal of Clinical Densitometry","volume":"26 3","pages":"Article 101418"},"PeriodicalIF":2.5,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10306155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}