Periprosthetic Bone Mineral Density Change after Total Knee Arthroplasty in Vietnamese Population

IF 1.7 4区医学 Q4 ENDOCRINOLOGY & METABOLISM

Journal of Clinical Densitometry Pub Date : 2025-03-22 DOI:10.1016/j.jocd.2025.101583

Hoc Nguyen Van , Khanh Nguyen Manh , Hoang Le Xuan

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引用次数: 0

Abstract

Objectives: After total knee arthroplasty (TKA), bone structure changes around prosthetics gradually appear. Adverse changes, such as decreased bone mineral density (BMD) and bone remodeling, can lead to joint loosening, affecting surgical outcomes. The study aims to detect BMD changes in the bone around the artificial knee early after TKA.

Methods: We performed a prospectively descriptive study on 54 patients who were operated at Viet Duc University Hospital from 4/2017 to 4/2019. Bone density was measured using dual-energy X-ray absorptiometry (DEXA) at the seventh days, 3,6,12, and 24 months post-surgery.

Results: The BMD in the medial metaphyseal region of interest decreased by 10.36 %, 11.5 %, 11.88 %, and 12.13 % at 3, 6, 12, and 24 months respectively, compared to 7 days post-surgery. The lateral metaphyseal region of interest decreased by 6.09 %, 6.47 %, 6.97 %, and 7.1 % and the tibial diaphyseal region of interest decreased by 3.75 %, 4.66 %, 5.91 %, and 5.8 % over the same follow-up periods. The BMD in the femoral condyle region of interest decreased by 8.15 %, 8.62 %, 9.24 %, and 10.65 % compared to the corresponding 7-day period at 3,6,12, and 24 months post-surgery.

Conclusion: The periprosthetic BMD rapidly reduced in the first 3 months, then gradually decreased. After 24 months of follow-up, the BMD in the medial metaphyseal region of interest decreased the most.

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来源期刊

Journal of Clinical Densitometry 医学-内分泌学与代谢

CiteScore

4.90

自引率

8.00%

发文量

审稿时长

90 days

期刊介绍： The Journal is committed to serving ISCD''s mission - the education of heterogenous physician specialties and technologists who are involved in the clinical assessment of skeletal health. The focus of JCD is bone mass measurement, including epidemiology of bone mass, how drugs and diseases alter bone mass, new techniques and quality assurance in bone mass imaging technologies, and bone mass health/economics. Combining high quality research and review articles with sound, practice-oriented advice, JCD meets the diverse diagnostic and management needs of radiologists, endocrinologists, nephrologists, rheumatologists, gynecologists, family physicians, internists, and technologists whose patients require diagnostic clinical densitometry for therapeutic management.