Journal of Clinical Sleep Medicine最新文献

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Reply to "Correspondence regarding 'Obstructive sleep apnea and primary snoring in children are associated with oropharyngeal dysbiosis and a mild compositional imbalance in the gastrointestinal tract'". 回复“关于‘儿童阻塞性睡眠呼吸暂停和原发性打鼾与口咽生态失调和胃肠道轻度成分失衡有关’的信函”。
IF 3.4 3区 医学
Journal of Clinical Sleep Medicine Pub Date : 2026-07-20 DOI: 10.1007/s44470-026-00141-4
Jennifer Hudson, Azleena Akhand, Moe Thant Nwe, Michael J Coffey, Josie van Dorst, Sandra Chuang, Chee Y Ooi
{"title":"Reply to \"Correspondence regarding 'Obstructive sleep apnea and primary snoring in children are associated with oropharyngeal dysbiosis and a mild compositional imbalance in the gastrointestinal tract'\".","authors":"Jennifer Hudson, Azleena Akhand, Moe Thant Nwe, Michael J Coffey, Josie van Dorst, Sandra Chuang, Chee Y Ooi","doi":"10.1007/s44470-026-00141-4","DOIUrl":"10.1007/s44470-026-00141-4","url":null,"abstract":"","PeriodicalId":50233,"journal":{"name":"Journal of Clinical Sleep Medicine","volume":"22 1","pages":""},"PeriodicalIF":3.4,"publicationDate":"2026-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13385557/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148537672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correction: Association between sleep inertia and cognitive performance among older adults in the Wisconsin Sleep Cohort study. 更正:威斯康星州睡眠队列研究中老年人睡眠惯性和认知表现之间的关系。
IF 3.4 3区 医学
Journal of Clinical Sleep Medicine Pub Date : 2026-07-20 DOI: 10.1007/s44470-026-00148-x
Jessica J Love, Jesse D Cook, Erika W Hagen, Amanda Rasmunon, Laurel A Ravelo, Mari Palta, Paul E Peppard, David T Plante
{"title":"Correction: Association between sleep inertia and cognitive performance among older adults in the Wisconsin Sleep Cohort study.","authors":"Jessica J Love, Jesse D Cook, Erika W Hagen, Amanda Rasmunon, Laurel A Ravelo, Mari Palta, Paul E Peppard, David T Plante","doi":"10.1007/s44470-026-00148-x","DOIUrl":"10.1007/s44470-026-00148-x","url":null,"abstract":"","PeriodicalId":50233,"journal":{"name":"Journal of Clinical Sleep Medicine","volume":"22 1","pages":""},"PeriodicalIF":3.4,"publicationDate":"2026-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13385528/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148537668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
From sleep health to insomnia: signal detection performance of the Ru-SATED scale. 从睡眠健康到失眠:ru - sas量表的信号检测性能。
IF 3.4 3区 医学
Journal of Clinical Sleep Medicine Pub Date : 2026-07-17 DOI: 10.1007/s44470-026-00126-3
Julia T Boyle, Spencer A Nielson, Jiale Xu, Runtang Meng, Junqi Zhang, Joseph M Dzierzewski
{"title":"From sleep health to insomnia: signal detection performance of the Ru-SATED scale.","authors":"Julia T Boyle, Spencer A Nielson, Jiale Xu, Runtang Meng, Junqi Zhang, Joseph M Dzierzewski","doi":"10.1007/s44470-026-00126-3","DOIUrl":"10.1007/s44470-026-00126-3","url":null,"abstract":"<p><strong>Purpose: </strong>This study examined the ability of the Ru-SATED scale to detect elevated insomnia symptoms, and explored whether signal detection varied by sex or age.</p><p><strong>Methods: </strong>U.S. adults ages 19-99 (N=3284; M<sub>age</sub>=42.7±16.7; 45% male) completed online versions of the Ru-SATED and Insomnia Severity Index (ISI) measures, measuring sleep health and insomnia symptom severity, respectively. Receiver operating characteristic (ROC) analyses, examining criterion-related validity, were performed to identify the optimal Ru-SATED score to identify elevated insomnia symptoms based on an ISI total score ≥10. The area under the curve, sensitivity, specificity, and accuracy were calculated to evaluate the model's performance at different values. Exploratory subgroup analyses evaluated performance across age and sex.</p><p><strong>Results: </strong>ROC analyses identified a Ru-SATED score of ≤8 had the strongest signal detection performance for detecting elevated insomnia symptoms. However, exploratory analyses suggested a lower score of ≤7 for young adults and a higher score of ≤9 for female participants.</p><p><strong>Conclusion: </strong>Ru-SATED scores contain an insomnia-related signal, consistent with a conceptual overlap between multidimensional sleep health and insomnia symptoms. These findings provide evidence of the scale's criterion-related validity and support its potential utility in population-based sleep-health research.</p><p><strong>Current knowledge/study rationale: </strong>The Ru-SATED assesses domains that conceptually overlap with insomnia symptoms, yet little is known about how well sleep-health scores capture insomnia symptoms. This study evaluated the criterion-related validity of the Ru-SATED scale by examining its ability to detect elevated insomnia symptom burden (ISI ≥10) in a large U.S. adult sample and explored whether performance varied by age or sex.</p><p><strong>Study impact: </strong>Ru-SATED scores demonstrated meaningful signal detection performance for identifying individuals with elevated insomnia symptoms, supporting the scale's criterion-related validity and highlighting conceptual links between sleep health and insomnia symptoms. Exploratory subgroup analyses suggested demographic variability in performance, underscoring the need for special attention in unique populations. These findings support the use of Ru-SATED in population-based sleep-health research and clarify how sleep-health dimensions relate to insomnia symptoms.</p>","PeriodicalId":50233,"journal":{"name":"Journal of Clinical Sleep Medicine","volume":"22 1","pages":""},"PeriodicalIF":3.4,"publicationDate":"2026-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13379525/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148473979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Objective and subjective adherence to oral appliance therapy in adults with obstructive sleep apnea: pilot data from a one-year longitudinal study. 成人阻塞性睡眠呼吸暂停患者对口腔器械治疗的客观和主观依从性:一项为期一年的纵向研究的试点数据
IF 3.4 3区 医学
Journal of Clinical Sleep Medicine Pub Date : 2026-07-17 DOI: 10.1007/s44470-026-00123-6
Wanxin Zhang, Min Yu, Xu Gong, Weijing Dang, Xuemei Gao
{"title":"Objective and subjective adherence to oral appliance therapy in adults with obstructive sleep apnea: pilot data from a one-year longitudinal study.","authors":"Wanxin Zhang, Min Yu, Xu Gong, Weijing Dang, Xuemei Gao","doi":"10.1007/s44470-026-00123-6","DOIUrl":"10.1007/s44470-026-00123-6","url":null,"abstract":"<p><strong>Objectives: </strong>To evaluate objective and subjective adherence to oral appliance (OA) therapy in obstructive sleep apnea (OSA) and identify predictors of adherence.</p><p><strong>Methods: </strong>Forty-nine adults with OSA (27 males, 22 females) underwent baseline polysomnography, sleep questionnaires, craniofacial measurements, and personality assessment. Objective adherence was monitored for 3 months using an embedded thermal microsensor. Subjective adherence was self-reported at 3 and 12 months. Predictors of adequate adherence (mean nightly use ≥ 4 h) were identified using multivariate logistic regression under a modified intention-to-treat approach.</p><p><strong>Results: </strong>OA therapy reduced AHI from 16.6 ± 10.3 to 4.16 ± 3.05 events/h. Forty-three participants (87.8%) completed the 3-month follow-up, and were all contacted at 12 months. During the first 3 months, mean use was 7.05 h on nights worn and 3.85 h/night overall, with OA used on 3.7 days/week and ≥ 4 h on 55.7% of nights. Participants overestimated use frequency (P < 0.001) but not nightly duration. At 3 months, 49% were adherent, showing stable use, whereas non-adherent users wore the appliance on fewer nights; at 12 months, 44% remained adherent, while most non-adherent users discontinued therapy. Older age and lower baseline ESS predicted 3-months adherent, while older age and smaller mandibular plane angle predicted 12-months adherent.</p><p><strong>Conclusion: </strong>Adherence to this type of OA was suboptimal in this study, with patients overestimating use frequency but accurately reporting nightly duration. Older age predicted adherence at both 3 and 12 months, while lower baseline sleepiness and smaller mandibular plane angle were associated with 3- and 12-month adherence, respectively.</p><p><strong>Current knowledge/study rationale: </strong>Subjective adherence to oral appliance (OA) therapy in patients with obstructive sleep apnea (OSA) may overestimate actual device use, whereas longitudinal adherence patterns and their clinical implications remain poorly understood.</p><p><strong>Study impact: </strong>Objective adherence to OA therapy was substantially lower than self-reported adherence, particularly among poorly adherent patients. Early adherence patterns may help clinicians identify patients who require additional adherence support. In the absence of regular adherence reminders, OA use frequency remained insufficient, potentially limiting the systemic benefits of OA therapy for OSA. Long-term, objective, and individualized adherence care and monitoring may be important in routine clinical practice.</p>","PeriodicalId":50233,"journal":{"name":"Journal of Clinical Sleep Medicine","volume":"22 1","pages":""},"PeriodicalIF":3.4,"publicationDate":"2026-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13379559/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148473954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Establishing polysomnographic criteria for initiation of non-invasive ventilation in children with neuromuscular diseases. 建立儿童神经肌肉疾病无创通气的多导睡眠图标准。
IF 3.4 3区 医学
Journal of Clinical Sleep Medicine Pub Date : 2026-07-17 DOI: 10.1007/s44470-026-00102-x
Vanessa Campes Dannenberg, Reshma Amin, Gregory Anagnostopoulos, Adetayo Adeleye, Glenda N Bendiak, Hanna Kolski, Maria L Castro-Codesal
{"title":"Establishing polysomnographic criteria for initiation of non-invasive ventilation in children with neuromuscular diseases.","authors":"Vanessa Campes Dannenberg, Reshma Amin, Gregory Anagnostopoulos, Adetayo Adeleye, Glenda N Bendiak, Hanna Kolski, Maria L Castro-Codesal","doi":"10.1007/s44470-026-00102-x","DOIUrl":"10.1007/s44470-026-00102-x","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Study objectives: &lt;/strong&gt;This study aims to (1) assess agreement for polysomnography (PSG)-based criteria for non-invasive ventilation (NIV) initiation between the American College of Chest Physicians (CHEST) neuromuscular guidelines, American Academy of Sleep Medicine (AASM) definitions for nocturnal hypoventilation and pediatric obstructive sleep apnea (OSA), and authors' proposed rapid eye movement (REM)-related criteria and (2) compare clinical outcomes and NIV adherence within 12 months in children with neuromuscular disorders (NMD).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;Multicenter retrospective study of children with NMD recommended NIV between 2010 and 2023. We classified participants in 3 groups based on described criteria. Kappa and Wilcoxon signed-rank were used to assess agreement and compare groups.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Of 115 participants (88 male, median age 11.8 years [IQR 7-15]), 71% met at least one NIV initiation criterion across all groups. Twenty-five percent had nocturnal hypoventilation by CHEST guidelines, 16% by REM-related criteria and 9% AASM-based criteria. Nocturnal hypoxemia was diagnosed in 22% (CHEST) and 19% (REM-related). Overall agreement was moderate between REM-related and CHEST criteria (k = 0.71; CI95% 0.47-0.95; p &lt; 0.001). Apnea-hypopnea index agreement was strong between CHEST and AASM-based criteria (k = 0.86, CI95% 0.74-0.98; p &lt; 0.001). Nocturnal hypoxemia agreement was moderate between CHEST and REM-related criteria (k = 0.69, CI95% 0.49-0.89; p &lt; 0.001). From the 96% (n = 111) of children that started NIV, 73% (n = 84) maintained its use for 6-12 months, with no differences in adherence or clinical outcomes across groups.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;Findings support new CHEST guidelines integrate disease and REM-specific criteria to enhance timely NIV initiation for early signs of nocturnal hypoventilation or hypoxemia in children with NMD.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Current knowledge/study rationale: &lt;/strong&gt;The American College of Chest Physicians (CHEST) guidelines recommend starting non-invasive ventilation (NIV) before advanced sleep-disordered breathing (SDB) develops. However, it remains unclear whether these criteria fully capture the progressive nature of SDB in children and youth with neuromuscular disorders (NMD), which often begins in rapid eye movement (REM) sleep and later affects all stages.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Study impact: &lt;/strong&gt;Our study demonstrated that CHEST and REM-related criteria detect more children with early sleep-disordered breathing (SDB), especially those with CO&lt;sub&gt;2&lt;/sub&gt; retention or hypoxemia not captured by American Academy of Sleep Medicine (AASM) standards. These findings support continued exploration of inclusive and physiologically grounded criteria for NIV initiation in pediatric NMD populations and align with growing recognition that current standard thresholds may be overly restrictive, potentially excluding children who experience progressive SDB","PeriodicalId":50233,"journal":{"name":"Journal of Clinical Sleep Medicine","volume":"22 1","pages":""},"PeriodicalIF":3.4,"publicationDate":"2026-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13379531/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148473943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Delayed school start times to improve sleep duration and mitigate depression in adolescents: a systematic review and meta-analysis. 延迟上学时间改善青少年睡眠时间和减轻抑郁:一项系统回顾和荟萃分析。
IF 3.4 3区 医学
Journal of Clinical Sleep Medicine Pub Date : 2026-07-14 DOI: 10.1007/s44470-026-00116-5
Richard C Wang, Maximilian I Lee, Guru S Aroul, Tinsley E Silcox, Daniel I Lipin
{"title":"Delayed school start times to improve sleep duration and mitigate depression in adolescents: a systematic review and meta-analysis.","authors":"Richard C Wang, Maximilian I Lee, Guru S Aroul, Tinsley E Silcox, Daniel I Lipin","doi":"10.1007/s44470-026-00116-5","DOIUrl":"10.1007/s44470-026-00116-5","url":null,"abstract":"<p><strong>Background and objectives: </strong>Delayed school start time (DSST) has been associated with prolonged sleep duration and reduced depressive symptoms. However, the overall magnitude of these effects remains unclear. We therefore conducted a systematic review and meta-analysis to assess the impact of DSST on sleep duration and depressive symptoms among middle and high school students.</p><p><strong>Methods: </strong>We systematically searched Medline, Google Scholar, and Science Direct for studies examining the relationship between DSST and both sleep duration and depression. Four independent reviewers conducted risk-of-bias and quality assessments for each study. For quantitative synthesis, we calculated the standardized mean difference (SMD) using Hedges's g to evaluate changes in sleep duration and depression.</p><p><strong>Results: </strong>A total of six studies were included in the final meta-analysis. The pooled analysis indicated that DSST was associated with an average increase in sleep duration of 69 min, with an SMD of 0.63, suggesting a moderate effect size. In contrast, analysis of depressive symptoms, based on five studies, produced a pooled SMD of - 0.20, indicating a smaller effect. Both analyses demonstrated high inter-study heterogeneity.</p><p><strong>Conclusions: </strong>Our findings suggest that DSST is associated with a moderate improvement in sleep duration among middle and high school students, with minimal evidence of publication bias and small-studies effect, while depressive symptoms showed a small reduction. Further research with larger sample sizes and standardized outcome measures is warranted to clarify these associations.</p>","PeriodicalId":50233,"journal":{"name":"Journal of Clinical Sleep Medicine","volume":"22 1","pages":""},"PeriodicalIF":3.4,"publicationDate":"2026-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13369063/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148450372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Limitations in study of actigraphic estimates of sleep. 睡眠活动图估计研究的局限性。
IF 3.4 3区 医学
Journal of Clinical Sleep Medicine Pub Date : 2026-07-13 DOI: 10.1007/s44470-026-00132-5
Ahad Wali Khan, Aisha Riaz
{"title":"Limitations in study of actigraphic estimates of sleep.","authors":"Ahad Wali Khan, Aisha Riaz","doi":"10.1007/s44470-026-00132-5","DOIUrl":"10.1007/s44470-026-00132-5","url":null,"abstract":"","PeriodicalId":50233,"journal":{"name":"Journal of Clinical Sleep Medicine","volume":"22 1","pages":""},"PeriodicalIF":3.4,"publicationDate":"2026-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13365276/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148438740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Leveraging convenient wearable technology to assess adolescent sleep: physical and behavioral health correlates of single-channel sleep electroencephalogram in a community sample of youth. 利用方便的可穿戴技术评估青少年睡眠:社区青少年样本中单通道睡眠脑电图的身体和行为健康相关性
IF 3.4 3区 医学
Journal of Clinical Sleep Medicine Pub Date : 2026-07-13 DOI: 10.1007/s44470-026-00118-3
Jamie L Flannery, Matthew M Engelhard, Sujay Kansagra, Scott H Kollins, Andrew Krystal, Jessica R Lunsford-Avery
{"title":"Leveraging convenient wearable technology to assess adolescent sleep: physical and behavioral health correlates of single-channel sleep electroencephalogram in a community sample of youth.","authors":"Jamie L Flannery, Matthew M Engelhard, Sujay Kansagra, Scott H Kollins, Andrew Krystal, Jessica R Lunsford-Avery","doi":"10.1007/s44470-026-00118-3","DOIUrl":"10.1007/s44470-026-00118-3","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Study objectives: &lt;/strong&gt;Sleep disturbances during adolescence heighten risk for physical and behavioral health problems, yet sleep physiological markers critical to health outcomes are rarely assessed in pediatric care. Wearable single-channel electroencephalography (EEG) devices may offer scalable, ecologically valid methods for assessing sleep physiology in home settings. This study evaluated whether single-channel sleep-EEG metrics were associated with physical and behavioral health in adolescents.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;Eighty-five community-derived adolescents (ages 11-17, 50% female) completed seven consecutive nights of at-home, single-channel sleep-EEG, physical health assessments (i.e., body mass index and blood pressure), and subjective sleep and behavioral health measures. Parents provided psychiatric diagnosis history.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Odds of being overweight/obese decreased with greater REM duration (- 2.72% per minute) and higher REM percentage (- 100% per 1%). Odds of hypertension decreased with greater time spent in stage 3 (N3) (- 4.78% per minute). Multivariate analyses showed reduced N3 sleep was associated with parent-reported ADHD symptoms, whereas shorter total sleep time, lower sleep efficiency (SE), and longer sleep onset latency (SOL) were associated with higher adolescent-reported ADHD and conduct problems (p's &lt; .05). Odds of an ADHD diagnosis increased with longer SOL (+ 1.92% per minute) and slower N3 decline (+ 89.4% per 0.01 units) but decreased with higher SE (- 7.78% per 1%). Odds of an internalizing disorder increased with higher SE (+ 12.4% per 1%) and greater wake after sleep onset (+ 3.18% per minute), but decreased with more REM sleep (- 9.62% per minute).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;Findings highlight the clinical value of wearable sleep-EEG for detecting sleep-related risk processes during adolescence. By capturing physiological features not accessible through self-report, at-home sleep-EEG may flag youth who could benefit from sleep-focused interventions, complementing routine care in identifying risk of future health problems. Integrating such tools into pediatric settings could support more precise, developmentally informed approaches to prevention and intervention.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Current study/study rationale: &lt;/strong&gt;Sleep disturbances are common during adolescence and increase risk for physical conditions such as obesity and hypertension, as well as behavioral health problems, yet sleep physiology is rarely adequately assessed in pediatric care. Wearable single-channel EEG offers an accessible way to capture sleep architecture and continuity that subjective reports cannot provide. This study shows that EEG-derived sleep features, including REM, N3 sleep, sleep efficiency, and sleep-onset latency, are associated with physical and behavioral health outcomes above and beyond adolescent and caregiver reports.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Study impact: &lt;/strong&gt;These finding","PeriodicalId":50233,"journal":{"name":"Journal of Clinical Sleep Medicine","volume":"22 1","pages":""},"PeriodicalIF":3.4,"publicationDate":"2026-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13365060/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148438725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Antidepressant medications have differential effects on REM sleep without atonia quantified by chin and upper extremity EMG. 抗抑郁药物对无张力的快速眼动睡眠有不同的影响,通过下巴和上肢肌电图量化。
IF 3.4 3区 医学
Journal of Clinical Sleep Medicine Pub Date : 2026-07-09 DOI: 10.1007/s44470-026-00127-2
Jad El Ahdab, Carlos L Rodriguez, Madeleine Grigg-Damberger, Matheus Lima Diniz Araujo, Noah D Andrews, Sikawat Thanaviratananich, Nancy Foldvary-Schaefer
{"title":"Antidepressant medications have differential effects on REM sleep without atonia quantified by chin and upper extremity EMG.","authors":"Jad El Ahdab, Carlos L Rodriguez, Madeleine Grigg-Damberger, Matheus Lima Diniz Araujo, Noah D Andrews, Sikawat Thanaviratananich, Nancy Foldvary-Schaefer","doi":"10.1007/s44470-026-00127-2","DOIUrl":"10.1007/s44470-026-00127-2","url":null,"abstract":"<p><strong>Objective: </strong>To determine associations between video polysomnography (vPSG)-quantified REM sleep without atonia (RSWA) and antidepressants (ADs) including selective serotonin reuptake inhibitors (SSRIs), serotonin norepinephrine reuptake inhibitors (SNRIs), and tricyclic antidepressants (TCAs).</p><p><strong>Methods: </strong>We analyzed 1474 vPSGs scored for possible REM sleep behavior disorder (RBD). RSWA scoring was based on submentalis and flexor digitorum superficialis (FDS) EMG using AASM criteria. Percent REM epochs meeting RSWA criteria (RSWA%) were compared by medication class in monotherapy or combination therapies using linear regression analysis, and adjusting for age, body mass index, gender, and race.</p><p><strong>Results: </strong>The sample included 1474 patients, 624 (42.3%) taking ADs and 850 (57.7%) non-users. Mean age was 53 ± 16.4 years, 53.1% male, and 73.1% White. Overall RSWA% was 11.9 ± 17.8. Compared to those medication-free, patients on SSRI or SNRI monotherapy had a 3.39% and 6.66% increase in RSWA%, respectively (p < 0.009 and p < 0.001); those on both SSRI and SNRI had a 10.44% increase (p = 0.089). In contrast, RSWA% did not increase in patients taking TCA monotherapy or the combination of SSRI + TCA or SNRI + TCA.</p><p><strong>Conclusion: </strong>Use of SSRIs and SNRIs, but not TCAs, is associated with increased RSWA% in a population with suspected parasomnia. The highest RSWA% estimates among combination groups were observed with SSRI + SNRI, although combination subgroup findings should be interpreted cautiously given small sample sizes. This study is the largest to quantify RSWA% and identify the differential impact of AD class, and monotherapy versus combination therapy on RSWA%. These findings should be interpreted within the context of the clinical criteria used for RSWA scoring.</p>","PeriodicalId":50233,"journal":{"name":"Journal of Clinical Sleep Medicine","volume":"22 1","pages":""},"PeriodicalIF":3.4,"publicationDate":"2026-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13350564/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148425961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reply to "The question of whether narcolepsy increases mortality should be answered based on reliable studies". 回复“发作性睡病是否会增加死亡率的问题应该基于可靠的研究来回答”。
IF 3.4 3区 医学
Journal of Clinical Sleep Medicine Pub Date : 2026-07-09 DOI: 10.1007/s44470-026-00121-8
Amir Sharafkhaneh, Ahmed S BaHammam, Yves Dauvilliers, Mehnaz Azarian, Michael Thorpy, Fang Han, Gulcin Benbir Senel, Murat Aksu, Javad Razjouyan
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