Journal of Clinical Sleep Medicine最新文献

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COVID-19 infection and sleep health: findings from the nationally representative COVID-19's Unequal Racial Burden survey. COVID-19感染和睡眠健康:来自全国代表性的COVID-19不平等种族负担调查的结果。
IF 3.5 3区 医学
Journal of Clinical Sleep Medicine Pub Date : 2025-06-01 DOI: 10.5664/jcsm.11638
Dana M Alhasan, Symielle A Gaston, Paula D Strassle, Anna María Nápoles, Chandra L Jackson
{"title":"COVID-19 infection and sleep health: findings from the nationally representative COVID-19's Unequal Racial Burden survey.","authors":"Dana M Alhasan, Symielle A Gaston, Paula D Strassle, Anna María Nápoles, Chandra L Jackson","doi":"10.5664/jcsm.11638","DOIUrl":"10.5664/jcsm.11638","url":null,"abstract":"<p><strong>Study objectives: </strong>To estimate overall and racial/ethnic-specific associations between COVID-19 infection status and sleep health.</p><p><strong>Methods: </strong>We analyzed online survey data collected from December 2020 to February 2021 among Asian, Black, Latino (English- and Spanish-speaking), and White adults (n = 1,000 each), along with American Indian/Alaska Native, Native Hawaiian/Pacific Islander, and multiracial adults (n = 500). COVID-19 infection (confirmed, probable, suspected), based on self-reported data on symptoms and infected contacts, was classified using World Health Organization definitions. Sleep disturbances were categorized as \"yes\" (mild/moderate/severe) vs \"no\" (normal). Weighted analyses were used to generate nationally representative estimates within each racial/ethnic group. Adjusting for sociodemographic and health behaviors, Poisson regression with robust variance estimated prevalence ratios and confidence intervals for sleep disturbances among individuals with vs without a COVID-19 infection in the overall population and by gender, ability to get health care, and race/ethnicity.</p><p><strong>Results: </strong>Among 5,359 eligible participants, 24% had a COVID-19 infection. COVID-19 infection was associated with a 32% higher prevalence of sleep disturbances (PR = 1.32 [95% confidence interval: 1.22-1.42]). The higher prevalence of sleep disturbances among women with vs without COVID-19 (PR = 1.32 [1.19-1.45]) was similar to men (PR = 1.34 [1.18-1.53]). COVID-19 infection was associated with an even higher prevalence of sleep disturbances among participants who reported being able vs unable to get needed health care. COVID-sleep associations were higher among American Indian/Alaska Native (PR = 1.64 [1.30-2.09]), Native Hawaiian/Pacific Islander (PR = 1.53 [1.24-1.90]), and English-speaking Latino (PR = 1.49 [1.20-1.86]) adults compared to White adults (PR = 1.14 [0.93-1.41]), although confidence intervals overlapped.</p><p><strong>Conclusions: </strong>COVID-19 infections may lead to sleep disturbances among US adults.</p><p><strong>Citation: </strong>Alhasan DM, Gaston SA, Strassle PD, Nápoles AM, Jackson CL. COVID-19 infection and sleep health: findings from the nationally representative COVID-19's Unequal Racial Burden survey. <i>J Clin Sleep Med.</i> 2025;21(6):1053-1063.</p>","PeriodicalId":50233,"journal":{"name":"Journal of Clinical Sleep Medicine","volume":" ","pages":"1053-1063"},"PeriodicalIF":3.5,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12134591/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143617750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The influence of an innovative inspiratory pressure relief accessory on continuous positive airway pressure profiles in a laboratory bench setting. 创新的吸气减压附件对实验室工作台上持续气道正压曲线的影响。
IF 3.5 3区 医学
Journal of Clinical Sleep Medicine Pub Date : 2025-06-01 DOI: 10.5664/jcsm.11624
Geoffery P Sleeper, Kimber A Catullo, Pai-Lien Chen, Susheel P Patil, Kingman P Strohl, Ambrose A Chiang
{"title":"The influence of an innovative inspiratory pressure relief accessory on continuous positive airway pressure profiles in a laboratory bench setting.","authors":"Geoffery P Sleeper, Kimber A Catullo, Pai-Lien Chen, Susheel P Patil, Kingman P Strohl, Ambrose A Chiang","doi":"10.5664/jcsm.11624","DOIUrl":"10.5664/jcsm.11624","url":null,"abstract":"<p><strong>Study objectives: </strong>Despite its efficacy, long-term adherence to continuous positive airway pressure (CPAP) hovers around 50%. The V-Com (SleepRes, Murfreesboro, TN), an inspiratory pressure relief (IPR) accessory, claims to improve comfort by decreasing inspiratory pressures. We aim to independently assess its impact on fixed CPAP settings in a laboratory bench model.</p><p><strong>Methods: </strong>An ASL-5000 Breathing simulator (IngMar Medical, Pittsburgh, PA) with normal lung settings was employed. A ResMed AirSense 11 device was connected to ASL-5000 through a React Health Rio II exhalation vent and an elbow adapter. Mean inspiratory and expiratory pressures were measured at fixed CPAP settings (4, 6, 8, 10, 12, 14, 16, 18, and 20 cm H<sub>2</sub>O) at baseline, 1 IPR unit, and 2 IPR units in series, without and with expiratory pressure relief. Generalized linear models were applied to evaluate changes in pressure across CPAP settings.</p><p><strong>Results: </strong>With 1 IPR, mean inspiratory pressures decreased significantly from the baseline pressures (<i>P</i> < .001), with only a marginal reduction of mean expiratory pressures (<i>P</i> = .239). The inspiratory pressure reduction was consistently greater than the expiratory pressure drop across all settings (<i>P</i> < .001). Higher CPAP settings resulted in larger reductions in inspiratory and expiratory pressures (<i>P</i> < .001). Two IPR units in series led to a greater decrease in both pressures (<i>P</i> = .001). When expiratory pressure relief 3 was combined with IPR, a larger drop in pressure was noted (<i>P</i> < .001).</p><p><strong>Conclusions: </strong>This IPR accessory decreases inspiratory pressures but only marginally reduces expiratory pressures in this laboratory bench model. Two IPR units further decrease both inspiratory and expiratory pressures.</p><p><strong>Citation: </strong>Sleeper GP, Catullo KA, Chen P-L, Patil SP, Strohl KP, Chiang AA. The influence of an innovative inspiratory pressure relief accessory on continuous positive airway pressure profiles in a laboratory bench setting. <i>J Clin Sleep Med</i>. 2025;21(6):1073-1079.</p>","PeriodicalId":50233,"journal":{"name":"Journal of Clinical Sleep Medicine","volume":" ","pages":"1073-1079"},"PeriodicalIF":3.5,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12134585/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143617757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
When a trail leads to a highway: enhancing the understanding of hypertension in pediatric type 1 narcolepsy. 当一条小路通向一条高速公路:加强对儿童1型嗜睡症高血压的认识。
IF 3.5 3区 医学
Journal of Clinical Sleep Medicine Pub Date : 2025-06-01 DOI: 10.5664/jcsm.11720
Samson G Khachatryan, Elza A Balian, Lilit G Atabekyan
{"title":"When a trail leads to a highway: enhancing the understanding of hypertension in pediatric type 1 narcolepsy.","authors":"Samson G Khachatryan, Elza A Balian, Lilit G Atabekyan","doi":"10.5664/jcsm.11720","DOIUrl":"10.5664/jcsm.11720","url":null,"abstract":"","PeriodicalId":50233,"journal":{"name":"Journal of Clinical Sleep Medicine","volume":" ","pages":"971-972"},"PeriodicalIF":3.5,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12134581/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143797036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A case study on generative artificial intelligence to extract the fundamental sleep parameters from polysomnography notes. 生成式人工智能从多导睡眠记录中提取基本睡眠参数的案例研究。
IF 3.5 3区 医学
Journal of Clinical Sleep Medicine Pub Date : 2025-06-01 DOI: 10.5664/jcsm.11594
Arash Maghsoudi, Amir Sharafkhaneh, Mehrnaz Azarian, Amin Ramezani, Max Hirshkowitz, Javad Razjouyan
{"title":"A case study on generative artificial intelligence to extract the fundamental sleep parameters from polysomnography notes.","authors":"Arash Maghsoudi, Amir Sharafkhaneh, Mehrnaz Azarian, Amin Ramezani, Max Hirshkowitz, Javad Razjouyan","doi":"10.5664/jcsm.11594","DOIUrl":"10.5664/jcsm.11594","url":null,"abstract":"<p><p>Generative artificial intelligence utilizing transformer technology is widely seen as a groundbreaking advancement in applied artificial intelligence. The technology creates a unique opportunity to extract unstructured data from medical notes. In the current experiments, we extracted fundamental sleep parameters from polysomnography notes of veterans in the Corporate Data Warehouse national database using large language models. The \"SOLAR-10.7B-Instruct\" model extracted values associated with total sleep time, sleep onset latency, and sleep efficiency from the polysomnography notes. The model's performance was evaluated using 464 human annotated notes. The analysis showed close accuracy for the large language model compared to the human total sleep time and sleep efficiency extraction, and a considerable accuracy improvement (7.6%) in extracting sleep onset latency for the machine compared to human annotation. The large language model shows negligible hallucination (no more than 3.6%), and it has the capability to perform complicated reasoning to extract the desired sleep parameter.</p><p><strong>Citation: </strong>Maghsoudi A, Sharafkhaneh A, Azarian M, Ramezani A, Hirshkowitz M, Razjouyan J. A case study on generative artificial intelligence to extract the fundamental sleep parameters from polysomnography notes. <i>J Clin Sleep Med</i>. 2025;21(6):1123-1127.</p>","PeriodicalId":50233,"journal":{"name":"Journal of Clinical Sleep Medicine","volume":" ","pages":"1123-1127"},"PeriodicalIF":3.5,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12134583/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143517183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Home sleep apnea testing in patients with continuous flow left ventricular assist device: is it feasible? 连续流LVAD患者的家庭睡眠呼吸暂停测试:可行吗?
IF 3.5 3区 医学
Journal of Clinical Sleep Medicine Pub Date : 2025-06-01 DOI: 10.5664/jcsm.11606
Pornthira Mutirangura, Tamas Alexy, Sophia E Airhart, Jenna E Kay, Antonio C Christophy, Dominic Emerson, David Raymer, Andrew W Shaffer, Anthony W Castleberry, Marshall P Hyden, Karol Mudy, Benjamin Sun, Snigdha Pusalavidyasagar
{"title":"Home sleep apnea testing in patients with continuous flow left ventricular assist device: is it feasible?","authors":"Pornthira Mutirangura, Tamas Alexy, Sophia E Airhart, Jenna E Kay, Antonio C Christophy, Dominic Emerson, David Raymer, Andrew W Shaffer, Anthony W Castleberry, Marshall P Hyden, Karol Mudy, Benjamin Sun, Snigdha Pusalavidyasagar","doi":"10.5664/jcsm.11606","DOIUrl":"10.5664/jcsm.11606","url":null,"abstract":"<p><strong>Study objectives: </strong>The incidence of sleep-related breathing disorder remains unclear in patients with a continuous flow left ventricular assist device. Polysomnography (PSG) remains the gold standard for diagnosis, but logistical challenges make home sleep apnea testing a more practical alternative. WatchPat has failed to accurately diagnose sleep-related breathing disorder in this population. In contrast, the NOX-T3 utilizes more channels to monitor physiological variables, potentially offering improved diagnostic accuracy. Therefore, we aimed to validate the NOX-T3 vs PSG in detecting sleep-related breathing disorder in patients with a durable left ventricular assist device.</p><p><strong>Methods: </strong>This is a single-center, prospective, observational pilot study. Patients with left ventricular assist device who screened positive on the STOP-BANG Sleep Apnea Questionnaire were referred to sleep clinic. Patients recommended for PSG by a sleep physician underwent PSG and NOX-T3 simultaneously. Apnea-hypopnea index with the PSG and the respiratory event index using the NOX-T3 were compared as well as time spent with oxygen saturation ≤ 88% using Spearman's correlation. <i>P</i> values less than .05 were considered statistically significant.</p><p><strong>Results: </strong>Ten patients (8 males, 2 females) were enrolled. The average age was 54 ± 15 years and 9 were implanted with a HeartMate III device. There was a strong correlation between the apnea-hypopnea index obtained from NOX-T3 and PSG (<i>R</i><sup>2</sup> = .984) but the time spent with oxygen saturation ≤ 88% correlated poorly (<i>r</i> = .168). The tests identified the same 3 patients meeting the diagnostic criteria for obstructive sleep apnea.</p><p><strong>Conclusions: </strong>Our results suggest that the NOX-T3 home sleep apnea testing device is a useful tool in the comprehensive evaluation of sleep-related breathing disorder in patients with left ventricular assist device.</p><p><strong>Citation: </strong>Mutirangura P, Alexy T, Airhart SE, et al. Home sleep apnea testing in patients with continuous flow left ventricular assist device: is it feasible? <i>J Clin Sleep Med</i>. 2025;21(6):999-1005.</p>","PeriodicalId":50233,"journal":{"name":"Journal of Clinical Sleep Medicine","volume":" ","pages":"999-1005"},"PeriodicalIF":3.5,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12134573/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143574516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Erratum. 勘误表。
IF 3.5 3区 医学
Journal of Clinical Sleep Medicine Pub Date : 2025-06-01 DOI: 10.5664/jcsm.11670
{"title":"Erratum.","authors":"","doi":"10.5664/jcsm.11670","DOIUrl":"10.5664/jcsm.11670","url":null,"abstract":"","PeriodicalId":50233,"journal":{"name":"Journal of Clinical Sleep Medicine","volume":"21 6","pages":"1145"},"PeriodicalIF":3.5,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12134584/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144210093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nasal biomarker inflammatory profile in response to intranasal corticosteroids in pediatric obstructive sleep apnea syndrome. 儿童阻塞性睡眠呼吸暂停综合征鼻内皮质类固醇反应的鼻生物标志物炎症谱。
IF 3.5 3区 医学
Journal of Clinical Sleep Medicine Pub Date : 2025-06-01 DOI: 10.5664/jcsm.11604
Ambika G Chidambaram, Christopher M Cielo, Inna Chervoneva, Jonathan M Spergel, Ignacio E Tapia
{"title":"Nasal biomarker inflammatory profile in response to intranasal corticosteroids in pediatric obstructive sleep apnea syndrome.","authors":"Ambika G Chidambaram, Christopher M Cielo, Inna Chervoneva, Jonathan M Spergel, Ignacio E Tapia","doi":"10.5664/jcsm.11604","DOIUrl":"10.5664/jcsm.11604","url":null,"abstract":"<p><strong>Study objectives: </strong>Nasopharyngeal inflammation contributes to pediatric obstructive sleep apnea syndrome (OSAS). Intranasal corticosteroids (INCS) are used to treat pediatric OSAS; a randomized controlled trial showed an improvement in OSAS symptoms but without polysomnography or neurobehavioral outcome differences. There is a lack of data demonstrating an objective decrease in the nasal inflammatory biomarker profile associated with INCS. Hence, we evaluated the association of nasal inflammatory biomarker profile and response to INCS.</p><p><strong>Methods: </strong>Secondary analysis of a randomized controlled trial of INCS vs placebo in pediatric OSAS (n = 134). The difference in intranasal biomarkers (interleukin (IL)-4, IL-13, tumor necrosis factor-alpha) between the groups after 3 and 12 months was evaluated. The association of the nasal inflammatory biomarker profile and response to INCS was assessed. Multiple regression analysis was performed to identify clinical predictors of response to INCS.</p><p><strong>Results: </strong>There were no statistically significant differences in the nasal IL-4, IL-13, and tumor necrosis factor-alpha levels between INCS and placebo groups after 3 and 12 months of treatment. Within the INCS group, there was no statistically significant change in the nasal IL-4, IL-13, and tumor necrosis factor-alpha levels after 3 months of therapy based on responder status. However, among those who received INCS, obesity and a higher obstructive apnea-hypopnea index at baseline were clinical predictors of greater obstructive apnea-hypopnea index after 3 months (<i>P</i> = .038 and .002, respectively).</p><p><strong>Conclusions: </strong>INCS did not affect the nasal inflammatory biomarker profile in children with OSAS, including the responders. In addition, INCS is not recommended as a treatment option in children with obesity or high obstructive apnea-hypopnea index at baseline.</p><p><strong>Clinical trial registration: </strong>Registry: ClinicalTrials.gov; Name: Steroids for Pediatric Apnea Research in Kids (SPARK); URL: https://clinicaltrials.gov/study/NCT02180672; Identifier: NCT02180672.</p><p><strong>Citation: </strong>Chidambaram AG, Cielo CM, Chervoneva I, Spergel JM, Tapia IE. Nasal biomarker inflammatory profile in response to intranasal corticosteroids in pediatric obstructive sleep apnea syndrome. <i>J Clin Sleep Med</i>. 2025;21(6):1033-1040.</p>","PeriodicalId":50233,"journal":{"name":"Journal of Clinical Sleep Medicine","volume":" ","pages":"1033-1040"},"PeriodicalIF":3.5,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12134589/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143574520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical significance of sleepiness: an American Academy of Sleep Medicine position statement. 嗜睡的临床意义:美国睡眠医学学会的立场声明。
IF 3.5 3区 医学
Journal of Clinical Sleep Medicine Pub Date : 2025-06-01 DOI: 10.5664/jcsm.11658
Thomas M Heffron, Indira Gurubhagavatula, Lynn Marie Trotti, Fariha Abbasi-Feinberg, Alexandre Rocha Abreu, Anuja Bandyopadhyay, Vishesh K Kapur, David Kuhlmann, Jennifer L Martin, Eric J Olson, Susheel P Patil, Anita V Shelgikar, Emerson M Wickwire, James A Rowley
{"title":"Clinical significance of sleepiness: an American Academy of Sleep Medicine position statement.","authors":"Thomas M Heffron, Indira Gurubhagavatula, Lynn Marie Trotti, Fariha Abbasi-Feinberg, Alexandre Rocha Abreu, Anuja Bandyopadhyay, Vishesh K Kapur, David Kuhlmann, Jennifer L Martin, Eric J Olson, Susheel P Patil, Anita V Shelgikar, Emerson M Wickwire, James A Rowley","doi":"10.5664/jcsm.11658","DOIUrl":"10.5664/jcsm.11658","url":null,"abstract":"<p><p>Alertness is a necessity for well-being and performance, and sleepiness is associated with cognitive and functional impairments that can have a negative impact on performance, health, mood, safety, and quality of life. In severe cases, sleepiness can lead to debilitation, injury, or death. Sleepiness is a marker of insufficient sleep and is the major patient-reported symptom associated with disorders of sleep and wakefulness such as narcolepsy and obstructive sleep apnea. Excessive sleepiness-the inability to stay awake and alert during the major waking episodes of the day-is reported by one third of US adults. It is the position of the American Academy of Sleep Medicine that sleepiness is a critical patient-reported outcome that is associated with increased risk for adverse health effects and diminished quality of life. The evaluation and management of sleepiness is essential for patient safety and patient-centered care. The health care system must support the evaluation and management of sleepiness so that patients can experience restorative sleep and daytime alertness. More research and innovation are needed to improve the treatment of sleep-wake disorders, including studies in diverse populations that support the development of tailored therapies for daytime sleepiness.</p><p><strong>Citation: </strong>Heffron TM, Gurubhagavatula I, Trotti LM, et al. Clinical significance of sleepiness: an American Academy of Sleep Medicine position statement. <i>J Clin Sleep Med.</i> 2025;21(6):1103-1107.</p>","PeriodicalId":50233,"journal":{"name":"Journal of Clinical Sleep Medicine","volume":" ","pages":"1103-1107"},"PeriodicalIF":3.5,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12134574/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143617744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Measuring hypoglossal nerve stimulator outcomes. 测量舌下神经刺激效果。
IF 3.5 3区 医学
Journal of Clinical Sleep Medicine Pub Date : 2025-06-01 DOI: 10.5664/jcsm.11608
Eric J Kezirian
{"title":"Measuring hypoglossal nerve stimulator outcomes.","authors":"Eric J Kezirian","doi":"10.5664/jcsm.11608","DOIUrl":"10.5664/jcsm.11608","url":null,"abstract":"","PeriodicalId":50233,"journal":{"name":"Journal of Clinical Sleep Medicine","volume":" ","pages":"1143"},"PeriodicalIF":3.5,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12134592/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143411383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The effectiveness of high-flow nasal cannula therapy in comparison with continuous positive airway pressure therapy in patients with obstructive sleep apnea: an open-label randomized crossover trial. 高流量鼻插管治疗与持续气道正压治疗在阻塞性睡眠呼吸暂停患者中的有效性比较:一项开放标签随机交叉试验
IF 3.5 3区 医学
Journal of Clinical Sleep Medicine Pub Date : 2025-06-01 DOI: 10.5664/jcsm.11640
Siraj Wali, Ghadah Batawi, Ghufran Bin Afeef, Ahmad A Bamagoos, Arwa Jamal, Omar Kanbr, Ranya Alshumrani, Faris Alhejaili, M Safwan Badr
{"title":"The effectiveness of high-flow nasal cannula therapy in comparison with continuous positive airway pressure therapy in patients with obstructive sleep apnea: an open-label randomized crossover trial.","authors":"Siraj Wali, Ghadah Batawi, Ghufran Bin Afeef, Ahmad A Bamagoos, Arwa Jamal, Omar Kanbr, Ranya Alshumrani, Faris Alhejaili, M Safwan Badr","doi":"10.5664/jcsm.11640","DOIUrl":"10.5664/jcsm.11640","url":null,"abstract":"<p><strong>Study objectives: </strong>Continuous positive airway pressure (CPAP) is the most effective treatment for obstructive sleep apnea (OSA). However, its effectiveness is limited by poor long-term adherence. A few recent studies have investigated the effectiveness of high-flow nasal cannula (HFNC) in treating OSA; however, its role remains uncertain. This study aimed to determine the effectiveness of HFNC, compared with CPAP, in the treatment of patients with OSA.</p><p><strong>Methods: </strong>This prospective, open-label, randomized crossover trial was conducted on treatment-naïve, newly diagnosed patients with OSA. Participants underwent CPAP and HFNC titration studies in 1 of 2 crossover sequences. The American Academy of Sleep Medicine guidelines for CPAP titration were followed for titration of both CPAP and HFNC. The initial flow rate of HFNC was set at 10 L/min, and the flow rate was increased by 10 L/min, up to a maximum of 60 L/min, to eliminate all respiratory events.</p><p><strong>Results: </strong>Sixty-eight participants completed the study. Compared with the diagnostic polysomnography, the apnea-hypopnea index decreased by a median of 52% with HFNC therapy (18-77%, <i>P</i> value < .001). Clinically acceptable titration was observed in 48% of patients receiving HFNC therapy, whereas 53% experienced a ≥ 50% reduction in the apnea-hypopnea index. The efficacy of HFNC decreased as OSA severity increased. However, CPAP therapy provided superior control of OSA, with a lower apnea-hypopnea index (5.8 vs 16.6 events/h, <i>P</i> values < .001). Sleep architecture significantly improved with CPAP but declined with HFNC.</p><p><strong>Conclusions: </strong>HFNC serves as a viable option for patients intolerant to CPAP, although careful patient selection is essential.</p><p><strong>Clinical trial registration: </strong>Registry: ClinicalTrials.gov; Name: Effect of High Flow Nasal Cannula Versus Continues Positive Airway Pressure in Adults With Obstructive Sleep Apnea; URL: https://clinicaltrials.gov/study/NCT05475119; Identifier: NCT05475119.</p><p><strong>Citation: </strong>Wali S, Batawi G, Bin Afeef G, et al. The effectiveness of high-flow nasal cannula therapy in comparison with continuous positive airway pressure therapy in patients with obstructive sleep apnea: an open-label randomized crossover trial. <i>J Clin Sleep Med.</i> 2025;21(6):1023-1031.</p>","PeriodicalId":50233,"journal":{"name":"Journal of Clinical Sleep Medicine","volume":" ","pages":"1023-1031"},"PeriodicalIF":3.5,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12134588/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143574522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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