{"title":"Hard road to climb: blunted academic and professional trajectories and effort-reward imbalance for people with narcolepsy type 1.","authors":"Madeleine Grigg-Damberger, Susan Muraida","doi":"10.5664/jcsm.11718","DOIUrl":"https://doi.org/10.5664/jcsm.11718","url":null,"abstract":"","PeriodicalId":50233,"journal":{"name":"Journal of Clinical Sleep Medicine","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143797025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Samson G Khachatryan, Elza Balian, Lilit Atabekyan
{"title":"When a trail leads to a highway: enhancing the understanding of hypertension in pediatric type 1 narcolepsy.","authors":"Samson G Khachatryan, Elza Balian, Lilit Atabekyan","doi":"10.5664/jcsm.11720","DOIUrl":"https://doi.org/10.5664/jcsm.11720","url":null,"abstract":"","PeriodicalId":50233,"journal":{"name":"Journal of Clinical Sleep Medicine","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143797036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Predictive modeling of obstructive sleep apnea using pharyngeal MRI radiomics and clinical data.","authors":"Yibin Chen, Heng Xiao, Min Huang, Yingying Zheng, Xiaoyu Dong, Guohao Chen","doi":"10.5664/jcsm.11706","DOIUrl":"https://doi.org/10.5664/jcsm.11706","url":null,"abstract":"<p><strong>Study objectives: </strong>This study aims to assess the predictive performance of models combining pharyngeal MRI radiomics and clinical data for distinguishing severe and non-severe obstructive sleep apnea (OSA).</p><p><strong>Methods: </strong>A total of 106 patients were included in the study, with 48 patients having an AHI < 30 events/h and 58 patients having an AHI ≥ 30 events/h. Radiomics features were extracted from MRI images. After applying Minimum Redundancy and Maximum Relevance and Lasso with Cross-Validation for dimensionality reduction, radiomics models were developed using logistic regression (LR), support vector machine (SVM), random forest (RF), and gradient boosting machine (GBM). Age and BMI were used as clinical features to construct a combined model with radiomics features. The performance of the models was evaluated using F1 scores and the area under the Receiver Operating Characteristic curve (AUC).</p><p><strong>Results: </strong>A total of 129 radiomics features were extracted from MRI images. Following dimensionality reduction and feature selection, two radiomics features with significant predictive value were identified. The combined model, incorporating SVM (AUC=0.78, F1=0.75), RF (AUC=0.78, F1=0.74), GBM (AUC=0.79, F1=0.75), and LR (AUC=0.82, F1=0.80), demonstrated superior performance compared to models based solely on radiomics features. The radiomics-only models included SVM (AUC=0.76, F1=0.72), RF (AUC=0.73, F1=0.67), GBM (AUC=0.76, F1=0.73), and LR (AUC=0.78, F1=0.76). Among the combined models, LR achieved the highest predictive accuracy and classification performance.</p><p><strong>Conclusions: </strong>The combined model, integrating radiomics features with clinical characteristics, demonstrates a superior ability to distinguish between severe and non-severe OSA. This approach offers a non-invasive and effective new perspective for clinical decision-making.</p>","PeriodicalId":50233,"journal":{"name":"Journal of Clinical Sleep Medicine","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143797033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Influence of sleep architectural disruptions on evolution of atrial fibrillation.","authors":"Catherine M Heinzinger, Reena Mehra","doi":"10.5664/jcsm.11722","DOIUrl":"https://doi.org/10.5664/jcsm.11722","url":null,"abstract":"","PeriodicalId":50233,"journal":{"name":"Journal of Clinical Sleep Medicine","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143797027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alexander Gomez, Kathleen F Sarmiento, Connor Smith, Michael Mitchell, Diane Lee, Annette Totten, Elizabeth Sanders, Armand M Ryden, Jiyeon Seo, Sarathi Bhattacharyya, Brian Harris, Roberto Mempin, Isabel Moghtaderi, Yameena Jawed, Nikita Jambulingam, Jennifer Martin, Michelle Zeidler
{"title":"Effectiveness of mailed versus in-person PAP initiation in VA's TeleSleep program.","authors":"Alexander Gomez, Kathleen F Sarmiento, Connor Smith, Michael Mitchell, Diane Lee, Annette Totten, Elizabeth Sanders, Armand M Ryden, Jiyeon Seo, Sarathi Bhattacharyya, Brian Harris, Roberto Mempin, Isabel Moghtaderi, Yameena Jawed, Nikita Jambulingam, Jennifer Martin, Michelle Zeidler","doi":"10.5664/jcsm.11692","DOIUrl":"https://doi.org/10.5664/jcsm.11692","url":null,"abstract":"<p><strong>Study objectives: </strong>This study sought to evaluate whether telehealth set-up was non-inferior to in-person set-up for veterans initiating PAP therapy.</p><p><strong>Methods: </strong>PAP setups before and after the COVID-19 pandemic were identified at two VA health systems. Telehealth PAP set-ups occurred between March, 2020 and December 2021. The in-person PAP set ups occurred between January and December, 2019. PAP data was extracted for days 1-30 (month 1) and 60-90 (month 3). PAP use was compared between in-person and tele-medicine utilizing hours used per night, days used (out of 30 days), and residual AHI (among compliant users). Non-inferiority analyses were performed, using the following non-inferiority margins: 45 minutes for hours used, 4 days for days of usage, and 5 events per hour for residual AHI.</p><p><strong>Results: </strong>432 VA patients (93.5% male) who underwent PAP set up were included (224 in person; 208 telehealth). Non-inferiority was established for PAP usage at month 1 (90% CI=-0.31,0.53) and month 3 (90% CI=-0.18, 0.71), days used at month 1 (90% CI=-2.28, 1.33) and month 3 (90% CI=-1.75, 2.20), and residual AHI at month 1 (90% CI=-0.40, 1.62) and month 3 (90% CI=-0.69, 2.30).</p><p><strong>Conclusions: </strong>Initiation of PAP therapy via telehealth was non-inferior to in-person set up visits in terms of PAP adherence among Veterans who use VA care.</p>","PeriodicalId":50233,"journal":{"name":"Journal of Clinical Sleep Medicine","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143765703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Christian F Poets, Maite Aretxabaleta, Christina Weismann, Mirja Quante, Cornelia Wiechers, Bernd Koos
{"title":"Palatal plates for treating infants with Robin sequence.","authors":"Christian F Poets, Maite Aretxabaleta, Christina Weismann, Mirja Quante, Cornelia Wiechers, Bernd Koos","doi":"10.5664/jcsm.11480","DOIUrl":"10.5664/jcsm.11480","url":null,"abstract":"","PeriodicalId":50233,"journal":{"name":"Journal of Clinical Sleep Medicine","volume":" ","pages":"735-736"},"PeriodicalIF":3.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11965097/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142878601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"How adherent are children with Down syndrome and obstructive sleep apnea to positive airway pressure therapy?","authors":"Sanjeev V Kothare, Kristen Kelly-Pieper","doi":"10.5664/jcsm.11600","DOIUrl":"10.5664/jcsm.11600","url":null,"abstract":"","PeriodicalId":50233,"journal":{"name":"Journal of Clinical Sleep Medicine","volume":" ","pages":"617-618"},"PeriodicalIF":3.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11965106/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143257142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Stanford orthodontic airway plate treatment program for neonates with Pierre Robin sequence in the United States: nonsurgical alternative to neonatal mandibular distraction osteogenesis.","authors":"HyeRan Choo","doi":"10.5664/jcsm.11516","DOIUrl":"10.5664/jcsm.11516","url":null,"abstract":"","PeriodicalId":50233,"journal":{"name":"Journal of Clinical Sleep Medicine","volume":" ","pages":"737-738"},"PeriodicalIF":3.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11965101/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142865874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cost-utility analysis of a tiered diagnostic approach combining a screening model and polysomnography in pediatric obstructive sleep apnea.","authors":"Shenglong Xu, Yanru Li, Demin Han","doi":"10.5664/jcsm.11518","DOIUrl":"10.5664/jcsm.11518","url":null,"abstract":"<p><strong>Study objectives: </strong>Obstructive sleep apnea (OSA) is a common disorder in the pediatric population, primarily diagnosed through polysomnography (PSG). However, PSG can be expensive and is often limited in availability. This study aimed to develop a cost-effective diagnostic strategy by integrating a screening model with PSG.</p><p><strong>Methods: </strong>A retrospective analysis was conducted on children suspected of OSA. Screening models were initially constructed with machine learning techniques. Cost-utility analyses compared 3 diagnostic strategies: (1) PSG alone, (2) the screening model alone, and (3) the screening model-PSG combined, in the discovery and validation cohorts. Cost-utility was measured using the incremental net monetary benefit.</p><p><strong>Results: </strong>A total of 690 children were included. The logistic regression model using age, tonsil scale, OSA questionnaire-18 questions 1 and 2, and oxygen desaturation index 3% predicted OSA with an area under the curve of 0.91. In the cost-utility analysis, the \"PSG alone\" strategy, as the baseline, was the most beneficial (utility 0.9557) at Chinese yuan (CNY) 4,523.98. The \"screening model alone\" had 91.6% sensitivity and 59.3% specificity, offering lesser value (utility 0.9337) at CNY 6,071.51 (incremental net monetary benefit CNY -3,966.43) when compared to \"PSG alone.\" The \"screening model-PSG combined\" strategy increased sensitivity to 100%, specificity to 99.2%, and utility to 0.9554 at CNY 4,463.36, establishing it as the most cost-effective option with an incremental net monetary benefit of CNY 34.22. One-way sensitivity analyses and adaptation to United States cost parameters confirmed the robustness of these results.</p><p><strong>Conclusions: </strong>Using the screening model as a triage tool for PSG enhances the cost-effectiveness of pediatric OSA management.</p><p><strong>Citation: </strong>Xu S, Li Y, Han D. Cost-utility analysis of a tiered diagnostic approach combining a screening model and polysomnography in pediatric obstructive sleep apnea. <i>J Clin Sleep Med</i>. 2025;21(4):655-665.</p>","PeriodicalId":50233,"journal":{"name":"Journal of Clinical Sleep Medicine","volume":" ","pages":"655-665"},"PeriodicalIF":3.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11965090/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142820039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pei Chen, Yueying Wang, Jinjin Yuan, Ghada Bourjeily, Chang G Park, Bingqian Zhu, Bilgay Izci-Balserak
{"title":"Effectiveness of non-pharmacological sleep interventions in pregnancy: a systematic review and meta-analysis.","authors":"Pei Chen, Yueying Wang, Jinjin Yuan, Ghada Bourjeily, Chang G Park, Bingqian Zhu, Bilgay Izci-Balserak","doi":"10.5664/jcsm.11696","DOIUrl":"https://doi.org/10.5664/jcsm.11696","url":null,"abstract":"<p><strong>Study objectives: </strong>Sleep problems are common during pregnancy. Maintaining good sleep is critical to maternal and fetal health. The objective of this study was to evaluate the effectiveness of non-pharmacological interventions in improving sleep quality and duration during pregnancy, using objective and subjective sleep measures.</p><p><strong>Methods: </strong>This meta-analysis was conducted ensuring compliance with the Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines. We systematically searched five major electronic databases, PubMed, Cumulative Index to Nursing and Allied Health Literature, Embase, Web of Science, and Cochrane. Only randomized-control trials of non-pharmacological interventions to improve sleep in pregnancy were included. We used random or fixed effect models and pooled estimates as standardized mean differences with 95% confidence intervals (CI). Funnel plots and sensitivity analysis were used to assess publication bias and result robustness.</p><p><strong>Results: </strong>A total of 31 studies (N=3,307) were included. Meta-analysis revealed that non-pharmacological interventions significantly improved self-reported overall sleep quality (SMD=-0.99; 95% CI =-1.40, -0.58; I<sup>2</sup> = 96.3%). Subgroup analysis indicated that interventions initiated in late pregnancy (SMD=-0.88; 95% CI=-1.16, -0.60; I<sup>2</sup> =85.6%) or spanning different pregnancy stages were effective (SMD=-1.10; 95% CI=-1.97, -0.24; I<sup>2</sup>=98.1%). However, these interventions did not significantly affect sleep duration or efficiency, whether self-reported or objectively measured.</p><p><strong>Conclusions: </strong>Non-pharmacological interventions can improve self-reported sleep quality in pregnant women. Clinicians can tailor interventions based on pregnancy period and individual needs to manage their sleep disturbances.</p><p><strong>Systematic review registration: </strong>Registry: PROSPERO; Identifier: CRD42022372289.</p>","PeriodicalId":50233,"journal":{"name":"Journal of Clinical Sleep Medicine","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143755611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}